Functional Genomics

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  1. 2019
  2. Published

    Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1

    Papathanasiou, P., Erdmann, S., Leon-Sobrino, C., Sharma, K., Urlaub, H., Garrett, Roger Antony & Peng, Xu, 2019, In: RNA Biology. 16, 4, p. 557-565

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

    Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, Guillermo, 2019, In: Nature Communications. 10, 14 p., 4302.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Structure-Activity Study of an All-D Antimicrobial Octapeptide D2D

    Lone, A., Thomsen, T. T., Nielsen, J. E., Thulstrup, Peter Waaben, Klitgaard, R. N., Løbner-Olesen, Anders, Lund, R., Jenssen, H. & Hansen, Paul Robert, 2019, In: Molecules. 24, 24, 17 p., 4571.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Sulfolobus and SIRV2: An Enduring Love Story

    Bhoobalan, Yuvaraj, 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  6. Published

    Synthesis of Shld Derivatives, Their Binding to the Destabilizing Domain, and Influence on Protein Accumulation in Transgenic Plants

    Jørgensen, F. P., Madsen, D., Meldal, Morten Peter, Olsen, J. V., Petersen, Morten, Granhøj, J. & Bols, Mikael, 2019, In: Journal of Medicinal Chemistry. 62, 10, p. 5191-5216 26 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain

    Manav, M. C., Turnbull, K. J., Jurėnas, D., Garcia-Pino, A., Gerdes, K. & Brodersen, D. E., 2019, In: Structure. 27, 11, p. 1675-1685, e1-e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The Draft Genome of Hariotina reticulata (Sphaeropleales, Chlorophyta) Provides Insight into the Evolution of Scenedesmaceae

    Xu, Y., Li, L., Liang, H., Melkonian, B., Lorenz, M., Friedl, T., Petersen, Morten, Liu, Huan, Melkonian, M. & Wang, S., 2019, In: Protist. 170, 6, 6 p., 125684.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The Draft Genome of the Small, Spineless Green Alga Desmodesmus costato-granulatus (Sphaeropleales, Chlorophyta)

    Wang, S., Li, L., Xu, Y., Melkonian, B., Lorenz, M., Friedl, T., Petersen, Morten, Sahu, S. K., Melkonian, M. & Liu, Huan, 2019, In: Protist. 170, 6, 5 p., 125697.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The FANCM family Mph1 helicase localizes to the mitochondria and contributes to mtDNA stability

    Bernal, M., Yang, X., Lisby, Michael & Mazón, G., 2019, In: DNA Repair. 82, 11 p., 102684.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The PCNA interaction motifs revisited: thinking outside the PIP-box

    Prestel, Andreas, Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter & Kragelund, Birthe Brandt, 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD+

    Skjerning, R. B., Senissar, M., Winther, K. S., Gerdes, K. & Brodersen, D. E., 2019, In: Molecular Microbiology. 111, 1, p. 221-236

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus

    Guo, T., Han, W. & She, Q., 2019, In: RNA Biology. 16, 4, p. 549-556 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex

    Qian, H., Yu, H., Li, P., Zhu, E., Yao, Q., Tai, C., Deng, Z., Gerdes, K., He, X., Gan, J. & Ou, H., 2019, In: Nucleic Acids Research. 47, 14, p. 7690-7702

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2018
  16. Published

    Chromosome replication as a measure of bacterial growth rate during Escherichia coli infection in the mouse peritonitis model

    Haugan, M. S., Charbon, Godefroid, Frimodt-Møller, N. & Løbner-Olesen, Anders, 1 Dec 2018, In: Scientific Reports. 8, p. 1-13 14961.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    HipA-Mediated Phosphorylation of SeqA Does not Affect Replication Initiation in Escherichia coli

    Riber, Leise, Koch, B. M., Kruse, L. R., Germain, E. & Løbner-Olesen, Anders, 2 Nov 2018, In: Frontiers in Microbiology. 9, p. 1-9 2637.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    DNA Damage Repair and Drug Efflux as Potential Targets for Reversing Low or Intermediate Ciprofloxacin Resistance in E. coli K-12

    Klitgaard, R. N., Jana, B., Guardabassi, Luca, Nielsen, K. L. & Løbner-Olesen, Anders, 2 Jul 2018, In: Frontiers in Microbiology. 9, 6 p., 1438.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology

    Harms, A., Brodersen, D. E., Mitarai, Namiko & Gerdes, K., 7 Jun 2018, In: Molecular Cell. 70, 5, p. 768-784 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Update on non-typeable Haemophilus influenzae-mediated disease and vaccine development

    Jalalvand, F. & Riesbeck, K., 3 Jun 2018, In: Expert Review of Vaccines. 17, 6, p. 503-512

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Dissection of the antimicrobial and hemolytic activity of Cap18: generation of Cap18 derivatives with enhanced specificity

    Ebbensgaard, Anna Elisabeth, Mordhorst, H., Overgaard, M. T., Aarestrup, F. M. & Hansen, E. B., May 2018, In: PLOS ONE. 13, 5, p. 1-25 e0197742.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe

    Maki, T., Ogura, N., Haber, J. E., Iwasaki, H. & Thon, Genevieve, May 2018, In: PLOS Genetics. 14, 5, p. 1-25 e1007424.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Erratum: Formation of a viral replication focus in Sulfolobus cells infected by the rudivirus Sulfolobus islandicus rod-shaped virus 2 [Journal of Virology, 91, 13, (2017), (e00486-17)] DOI:10.1128/JVI.00486-17

    Martinez Alvarez, Laura, Deng, Ling & Peng, Xu, 1 Apr 2018, In: Journal of Virology. 92, 7, e01991-17.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  24. Published

    Long-term industrial metal contamination unexpectedly shaped diversity and activity response of sediment microbiome

    Jacquiod, S. J. A., Cyriaque, V., Riber, Leise, Al-Soud, W. A., Gillan, D. C., Wattiez, R. & Sørensen, Søren Johannes, 15 Feb 2018, In: Journal of Hazardous Materials. 344, p. 299-307 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Type III CRISPR-Cas System: Introduction And Its Application for Genetic Manipulations

    Liu, T., Pan, S., Li, Y., Peng, N. & She, Q., 1 Jan 2018, In: Current Issues in Molecular Biology. 26, p. 1-14 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    A Critical Role for Dna2 at Unwound Telomeres

    Markiewicz-Potoczny, M., Lisby, Michael & Lydall, D., 2018, In: Genetics. 209, 1, p. 129-141 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel

    Santner, P., Martins, J. M. D. S., Laursen, J. S., Behrendt, L., Riber, Leise, Olsen, Christian Adam, Arkin, I. T., Winther, Jakob R., Willemoës, Martin & Lindorff-Larsen, Kresten, 2018, In: Biochemistry. 57, 41, p. 5949-5956

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding

    Han, W., Stella, S., Zhang, Y., Guo, T., Sulek, K., Peng-Lundgren, L., Montoya, Guillermo & She, Q., 2018, In: Nucleic Acids Research. 46, 19, p. 10319-10330 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A Unified Resource for Tracking Anti-CRISPR Names

    Bondy-Denomy, J., Davidson, A. R., Doudna, J. A., Fineran, P. C., Maxwell, K. L., Moineau, S., Peng, Xu, Sontheimer, E. J. & Wiedenheft, B., 2018, In: CRISPR Journal. 1, 5, p. 304-305

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  30. Published

    A transcriptional factor B paralog functions as an activator to DNA damage-responsive expression in archaea

    Feng, X., Sun, M., Han, W., Liang, Y. X. & She, Q., 2018, In: Nucleic Acids Research. 46, 14, p. 7085-7096

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment

    la Cour, J. M., Gojkovic, P. W., Ambjorner, S. E. B., Bagge, J., Jensen, S. M., Panina, S. & Berchtold, Martin Werner, 2018, In: PLOS ONE. 13, 9, p. 1-13 e0204520.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Activation of the Stringent Response by Loading of RelA-tRNA Complexes at the Ribosomal A-Site

    Winther, K. S., Roghanian, Mohammad & Gerdes, K., 2018, In: Molecular Cell. 70, 1, p. 95-105, e1-e4 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea

    Sun, M., Feng, X., Liu, Z., Han, W., Liang, Y. X. & She, Q., 2018, In: Nucleic Acids Research. 46, 13, p. 6697-6711

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    An intriguing relationship between the cyclic diguanylate signaling system and horizontal gene transfer

    Madsen, Jonas Stenløkke, Hylling, Ole, Jacquiod, S. J. A., Pécastaings, S., Hansen, L. H., Riber, Leise, Vestergaard, G. A. & Sørensen, Søren Johannes, 2018, In: ISME Journal. 12, 9, p. 2330-2334 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity

    He, F., Bhoobalan, Yuvaraj, Van, L. B., Kjeldsen, A. L., Dedola, M., Makarova, K. S., Koonin, E. V., Brodersen, D. E. & Peng, Xu, 2018, In: Nature Microbiology. 3, 4, p. 461-469 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Anti-CRISPR-Based and CRISPR-Based Genome Editing of Sulfolobus islandicus Rod-Shaped Virus 2

    Mayo-Muñoz, D., He, F., Jørgensen, J. B., Madsen, P. K., Bhoobalan, Yuvaraj & Peng, Xu, 2018, In: Viruses. 10, 12, p. 1-17 695.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Common Chromosomal Fragile Sites - Conserved Failure Stories

    Voutsinos, Vasileios, Munk, S. H. N. & Østergaard, Vibe Hallundbæk, 2018, In: Genes. 9, 12, p. 1-16 580.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Comparative Effectiveness of Low-Volume Time-Efficient Resistance Training Versus Endurance Training in Patients With Heart Failure

    Munch, G. W., Rosenmeier, J. B., Petersen, Morten, Rinnov, A. R., Iepsen, U. W., Pedersen, Bente Klarlund & Mortensen, S. P., 2018, In: Journal of Cardiopulmonary Rehabilitation and Prevention. 38, 3, p. 175-181 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Coping with Reactive Oxygen Species to Ensure Genome Stability in Escherichia coli

    Mendoza-Chamizo, B., Løbner-Olesen, Anders & Charbon, Godefroid, 2018, In: Genes. 9, 11, 565.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Countermeasures to survive excessive chromosome replication in Escherichia coli

    Charbon, Godefroid, Riber, Leise & Løbner-Olesen, Anders, 2018, In: Current Genetics. 64, 1, p. 71-79 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    DNA damage as a consequence of NLR activation

    Rodriguez, Eleazar, Chevalier, J., El Ghoul, H., Voldum-Clausen, K., Mundy, J. & Petersen, Morten, 2018, In: PLOS Genetics. 14, 2, 17 p., e1007235.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Dependency of Heterochromatin Domains on Replication Factors

    Jahn, L. J., Mason, B., Brøgger, Peter, Toteva, T., Nielsen, D. K. & Thon, Genevieve, 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 2, p. 477-489 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Discovering novel hydrolases from hot environments

    Wohlgemuth, R., Littlechild, J., Monti, D., Schnorr, K., van Rossum, T., Siebers, B., Menzel, P., Kublanov, I. V., Rike, A. G., Skretas, G., Szabo, Z., Peng, Xu & Young, M. J., 2018, In: Biotechnology Advances. 36, 8, p. 2077-2100

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Diversity and Contributions to Nitrogen Cycling and Carbon Fixation of Soil Salinity Shaped Microbial Communities in Tarim Basin

    Ren, M., Zhang, Z., Wang, X., Zhou, Z., Chen, D., Zeng, H., Zhao, S., Chen, L., Hu, Y., Zhang, C., Liang, Y., She, Q., Zhang, Y. & Peng, N., 2018, In: Frontiers in Microbiology. 9, 14 p., 431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells

    Brunati, C., Thomsen, T. T., Gaspari, E., Maffioli, S., Sosio, M., Jabes, D., Løbner-Olesen, Anders & Donadio, S., 2018, In: The Journal of antimicrobial chemotherapy. 73, 2, p. 414-424 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells

    Pentzold, C., Shah, S. A., Hansen, Niels Richard, Le Tallec, B., Seguin-Orlando, A., Debatisse, M., Lisby, Michael & Østergaard, Vibe Hallundbæk, 2018, In: Nucleic Acids Research. 46, 3, p. 1280-1294 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Fluorescence recovery allows theimplementation of a fluorescence reporter gene platform applicable for the detection and quantification of horizontal gene transfer in anoxic environments

    Pinilla Redondo, Rafael, Riber, Leise & Sørensen, Søren Johannes, 2018, In: Applied and Environmental Microbiology. 84, 6, 9 p., e02507-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2

    Leshets, M., Ramamurthy, D., Lisby, Michael, Lehming, N. & Pines, O., 2018, In: Current Genetics. 64, 3, p. 697-712 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Functional and Expression Analyses of the Pneumocystis MAT Genes Suggest Obligate Sexuality through Primary Homothallism within Host Lungs

    Richard, S., Almeida, J. M. G. C. F., Cissé, O. H., Luraschi, A., Nielsen, Olaf, Pagni, M. & Hauser, P. M., 2018, In: mBio. 9, 1, 10 p., e02201-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Functional study of PAT mRNA decapping factors in Arabidopsis

    Zuo, Zhangli Thomsen, 2018, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  51. Published

    Identification of the archaeal regulatory network in DNA damage response

    Feng, X., 2018, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  52. Published

    Imaging of DNA Ultrafine Bridges in Budding Yeast

    Quevedo Rodriguez, O. & Lisby, Michael, 2018, Genome Instability: Methods and Protocols. Muzi-Falconi, M. & Brown, G. W. (eds.). Humana Press, p. 483-493 11 p. (Methods in Molecular Biology, Vol. 1672).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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