Back to the roots: deep view into the evolutionary history of ADP-ribosylation opened by the DNA-targeting toxin-antitoxin module DarTG

Research output: Contribution to journalComment/debateResearch

  • Alexander Harms
  • Kenn Gerdes

In this issue of Molecular Cell, Jankevicius et al. (2016) characterize the DarTG toxin-antitoxin module in which the DarT toxin ADP-ribosylates single-stranded DNA and the DarG antitoxin counteracts DarT by direct binding and by enzymatic removal of the ADP-ribosylation.

Original languageEnglish
JournalMolecular Cell
Volume64
Issue number6
Pages (from-to)1020-1021
Number of pages2
ISSN1097-2765
DOIs
Publication statusPublished - 15 Dec 2016

    Research areas

  • ADP-ribosylation, bacterial persistence, DarG, DarT, restriction-modification system, toxin-antitoxin module

ID: 174176314