Lotte Bang Pedersen

Lotte Bang Pedersen

Professor

ORCID: 0000-0002-9749-3758

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  1. Published

    Cellular signalling by primary cilia in development, organ function and disease

    Anvarian, Zeinab, Mykytyn, K., Mukhopadhyay, S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2019, In: Nature Reviews Nephrology. 15, p. 199-219

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Functional characterization of the first missense variant in CEP78, a founder allele associated with cone-rod dystrophy, hearing loss and reduced male fertility

    Ascari, G., Peelman, F., Farinelli, P., Rosseel, T., Lambrechts, N., Wunderlich, K. A., Wagner, M., Nikopoulos, K., Martens, P., Balikova, I., Derycke, L., Holtappels, G., Krysko, O., Van Laethem, T., De Jaegere, S., Guillemyn, B., De Rycke, R., De Bleecker, J., Creytens, D., Van Dorpe, J. & 11 others, Gerris, J., Bachert, C., Neuhofer, C., Walraedt, S., Bischoff, A., Pedersen, Lotte Bang, Klopstock, T., Rivolta, C., Leroy, B. P., De Baere, E. & Coppieters, F., 2020, In: Human Mutation. 41, 5, p. 998-1011 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

    Benmerah, A., Durand, B., Giles, R. H., Harris, T., Kohl, L., Laclef, C., Meilhac, S. M., Mitchison, H. M., Pedersen, Lotte Bang, Roepman, R., Swoboda, P., Ueffing, M. & Bastin, P., 2015, In: Cilia. 4, 5, 14 p.

    Research output: Contribution to journal › Conference article › Research

  4. Published

    Sensory cilia and integration of signal transduction in human health and disease.

    Christensen, Søren Tvorup, Pedersen, Lotte Bang, Schneider, L. & Satir, P., 2007, In: Traffic - International Journal of Intracellular Transport. 8, 2, p. 97-109 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) signaling

    Christensen, Søren Tvorup, Clement, C. A., Satir, P. & Pedersen, Lotte Bang, 2012, In: Journal of Pathology. 226, 2, p. 172-184 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) and transforming growth factor β (TGF-β) signaling

    Christensen, Søren Tvorup, Morthorst, Stine Kjær, Mogensen, J. B. & Pedersen, Lotte Bang, 2017, In: Cold Spring Harbor Perspectives in Biology. 9, 6, 18 p., a028167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Interaction between the Chlamydia trachomatis histone H1-like protein (Hc1) and DNA.

    Christiansen, G., Pedersen, Lotte Bang, Koehler, J. E., Lundemose, A. G. & Birkelund, S., 1993, In: Journal of Bacteriology. 175, 6, p. 1785-95 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

    Clement, C. A., Ajbro, K. D., Koefoed, K., Vestergaard, M. L., Veland, I. R., Perestrello Ramos H de Jesus, M., Pedersen, Lotte Bang, Benmerah, A., tcg964, tcg964, Larsen, Lars Allan & Christensen, Søren Tvorup, 2013, In: Cell Reports. 3, 6, p. 1806-1814 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Primary cilia and aberrant cell signaling in epithelial ovarian cancer

    Egeberg, D. L., Lethan, M., Manguso, R., Schneider, L., Awan, A., Jørgensen, T. S., Byskov, A. G., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Cilia. 1, 15, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

    Farooq, M., Lindbæk, L., Krogh, N., Doganli, C., Keller, C., Mönnich, M., Gonçalves, A. B., Sakthivel, S., Mang, Y., Fatima, A., Andersen, V. S., Hussain, M. S., Eiberg, H., Hansen, L., Kjaer, K. W., Gopalakrishnan, J., Pedersen, L. B., Møllgård, K., Nielsen, H., Baig, S. M. & 3 others, Tommerup, Niels, Christensen, Søren Tvorup & Larsen, Lars Allan, 2020, In: Nature Communications. 11, 16 p., 5816.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling

    Frikstad, K. M., Molinari, E., Thoresen, M., Ramsbottom, S. A., Hughes, F., Letteboer, S. J. F., Gilani, S., Schink, K. O., Stokke, T., Geimer, S., Pedersen, Lotte Bang, Giles, R. H., Akhmanova, A., Roepman, R., Sayer, J. A. & Patzke, S., 2019, In: Cell Reports. 28, 7, p. 1907-1922, e1-e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines

    Frikstad, K. M., Schink, K. O., Gilani, S., Pedersen, Lotte Bang & Patzke, S., 2022, In: Bio-protocol. 12, 6, 14 p., 4360.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome

    G. Aslanyan, M., Doornbos, C., D. Diwan, G., Anvarian, Zeinab, Beyer, T., Junger, K., E. C. van Beersum, S., Russell, R., Ueffing, M., Ludwig, A., Boldt, K., Pedersen, Lotte Bang & Roepman, R., 2023, In: Frontiers in Cell and Developmental Biology. 11, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis

    Goggolidou, P., L. Stevens, J., Agueci, F., Keynton, J., Wheway, G., T. Grimes, D., H. Patel, S., Hilton, H., Morthorst, S. K., DiPaolo, A., J. Williams, D., Sanderson, J., V. Khoronenkova, S., Powles-Glover, N., Ermakov, A., T. Esapa, C., Romero, R., L. Dianov, G., Briscoe, J., A. Johnson, C. & 2 others, Pedersen, Lotte Bang & P. Norris, D., 2014, In: Development. 141, p. 3966-3977 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

    Gonçalves, A. B., Hasselbalch, S. K., Joensen, B. B., Patzke, S., Martens, P., Ohlsen, S. K., Quinodoz, M., Nikopoulos, K., Suleiman, R., Jeppesen, M. P. D., Weiss, C., Christensen, Søren Tvorup, Rivolta, C., Andersen, J. S., Farinelli, P. & Pedersen, Lotte Bang, 2021, In: eLife. 10, 34 p., e63731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins

    Jiang, K., Toedt, G., Gouveia, S. M., Davey, N. E., Hua, S., Vaart, B. V. D., Grigoriev, I., Larsen, J., Pedersen, Lotte Bang, Bezstarosti, K., Lince-Faria, M., Demmers, J., Steinmetz, M. O., Gibson, T. J. & Akhmanova, A., 2012, In: Current biology : CB. 22, 19, p. 1800-1807 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Transient accumulation and bidirectional movement of KIF13B in primary cilia

    Juhl, A. D., Anvarian, Zeinab, Kuhns, S., Berges, J., Andersen, J. S., Wüstner, D. & Pedersen, Lotte Bang, 2023, In: Journal of Cell Science. 136, 5, 8 p., jcs259257.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Cilia and coordination of signaling networks during heart development

    Koefoed, K., Veland, I. R., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2014, In: Organogenesis. 10, 1, p. 108-125 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Endogenous Tagging of Ciliary Genes in Human RPE1 Cells for Live-Cell Imaging

    Kuhns, S., Juhl, A. D., Anvarian, Zeinab, Wüstner, D., Pedersen, Lotte Bang & Andersen, J. S., 2024, Methods in Molecular Biology. Humana Press, p. 147-166 20 p. (Methods in Molecular Biology, Vol. 2725).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis

    Kypri, E., Christodoulou, A., Maimaris, G., Lethan, M., Markaki, M., Lysandrou, C., Lederer, C., Tavernarakis, N., Geimer, S., Pedersen, Lotte Bang & Santama, N., 2014, In: Cellular and molecular life sciences : CMLS. 71, 3, p. 517-538 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Analysis of microtubule plus-end-tracking proteins in cilia

    Larsen, J., Grigoriev, I., Akhmanova, A. & Pedersen, Lotte Bang, 2013, Cilia, Part A. Marshall, W. F. (ed.). Elsevier, p. 105-122 18 p. (Methods in Enzymology, Vol. 524).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  23. Published

    Coordination of TGFβ/BMP signaling is associated with the primary cilium

    Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Primary cilia as dynamic and diverse signalling hubs in development and disease

    Mill, P., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2023, In: Nature Reviews. Genetics. 24, 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    ATP Production in Chlamydomonas reinhardtii Flagella by Glycolytic Enzymes

    Mitchell, B. F., Pedersen, Lotte Bang, Feely, M., Rosenbaum, J. L. & Mitchell, D. R., 2005, In: Molecular Biology of the Cell. 16, 10, p. 4509-18 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Analysis of caveolin in primary cilia

    Morthorst, Stine Kjær, Mogensen, J. B., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2020, Caveolae: Methods and Protocols. Blouin, C. M. (ed.). Humana Press, p. 27-41 (Methods in Molecular Biology, Vol. 2169).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  28. Published

    Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

    Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2018, In: F E B S Journal. 285, 24, p. 4535-4564

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling

    Morthorst, Stine Kjær, Nielsen, C., Farinelli, P., Anvarian, Zeinab, Rasmussen, C. B. R., Serra-Marques, A., Grigoriev, I., Altelaar, M., Fürstenberg, N., Ludwig, A., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2022, In: Journal of Cell Science. 135, 12, 10 p., jcs259471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Expression of the oncogenic, constitutive active Platelet-Derived Growth Factor Receptor alpha D842V mutant induces loss of primary cilia

    Nielsen, B. S., Schmid, F., Malinda, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., P63.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  32. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Analysis of the Function of a Putative 2,3-Diphosphoglyceric Acid-Dependent Phosphoglycerate Mutase from Bacillus subtilis

    Pearson, C. L., Loshon, C. A., Setlow, P., Pedersen, Lotte Bang & Setlow, B., 2000, In: Journal of Bacteriology. 182, 14, p. 4121-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Dissecting the molecular mechanisms of intraflagellar transport in Chlamydomonas.

    Pedersen, Lotte Bang, Geimer, S. & Rosenbaum, J. L., 2006, In: Current Biology. 16, 5, p. 450-459

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The lissencephaly protein Lis1 is present in motile mammalian cilia and requires outer arm dynein for targeting to Chlamydomonas flagella.

    Pedersen, Lotte Bang, Rompolas, P., Christensen, Søren Tvorup, Rosenbaum, J. L. & King, S. M., 2007, In: Journal of Cell Science. 120, Pt 5, p. 858-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Assembly of primary cilia.

    Pedersen, Lotte Bang, Veland, I. R., Schrøder, J. M. & Christensen, Søren Tvorup, 2008, In: Developmental Dynamics. 237, p. 1993-2006 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. The Microtubule plus end-tracking protein EB1 is localized to the flagellar tip and basal bodies in Chlamydomonas reinhardtii.

    Pedersen, Lotte Bang, Geimer, S., Sloboda, R. D. & Rosenbaum, J. L., 2003, In: Current Biology. 13, 22, p. 1969-74 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Chlamydomonas IFT172 is encoded by FLA11, interacts with CrEB1, and regulates IFT at the flagellar tip.

    Pedersen, Lotte Bang, Miller, M. S., Geimer, S., Leitch, J. M., Rosenbaum, J. L. & Cole, D. G., 2005, In: Current Biology. 15, 3, p. 262-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Intraflagellar Transport (IFT) Role in Ciliary Assembly, Resorption and Signalling

    Pedersen, Lotte Bang & Rosenbaum, J. L., 2008, In: Current Topics in Developmental Biology. 85, p. 23-61 38 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Characterization of ywhE, which encodes a putative high-molecular-weight class A penicillin-binding protein in Bacillus subtilis

    Pedersen, Lotte Bang, Ragkousi, K., Cammett, T. J., Melly, E., Sekowska, A., Schopick, E., Murray, T. & Setlow, P., 2000, In: Gene. 246, 1-2, p. 187-96 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Kif7 keeps cilia tips in shape

    Pedersen, Lotte Bang & Akhmanova, A., 2014, In: Nature Cell Biology. 16, 7, p. 623-625 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Tubulin transport in cilia: how many tubulin cargo-binding sites per IFT particle? (retrospective on DOI 10.1002/bies.201400007)

    Pedersen, Lotte Bang, 2017, In: BioEssays. 39, 1, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  43. Published

    The ciliary cytoskeleton

    Pedersen, Lotte Bang, Schrøder, J. M., Satir, P. & Christensen, Søren Tvorup, 2012, In: Comprehensive Physiology. 2, 1, p. 779-803 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Cilia and flagella

    Pedersen, Lotte Bang, Jurisch-Yaksi, N., Schmid, F. M. & Christensen, Søren Tvorup, 2023, Encyclopedia of Cell Biology, Second Edition. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Oxford: Elsevier, Vol. 3. p. 164-188 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  45. Published

    Regulating intraflagellar transport

    Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Nature Cell Biology. 14, 9, p. 904-906 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Purification of recombinant Chlamydia trachomatis histone H1-like protein Hc2, and comparative functional analysis of Hc2 and Hc1.

    Pedersen, Lotte Bang, Birkelund, S. & Christiansen, G., 1996, In: Molecular Microbiology. 20, 2, p. 295-311 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Most of the propeptide is dispensable for stability and autoprocessing of the zymogen of the germination protease of spores of Bacillus species.

    Pedersen, Lotte Bang, Nessi, C. & Setlow, P., 1997, In: Journal of Bacteriology. 179, 5, p. 1824-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The 18-kilodalton Chlamydia trachomatis histone H1-like protein (Hc1) contains a potential N-terminal dimerization site and a C-terminal nucleic acid-binding domain.

    Pedersen, Lotte Bang, Birkelund, S., Holm, A., Ostergaard, S. & Christiansen, G., 1996, In: Journal of Bacteriology. 178, 4, p. 994-1002 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Penicillin-Binding Protein-Related Factor A Is Required for Proper Chromosome Segregation in Bacillus subtilis

    Pedersen, Lotte Bang & Setlow, P., 2000, In: Journal of Bacteriology. 182, 6, p. 1650-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Endocytic control of cellular signaling at the primary cilium

    Pedersen, Lotte Bang, Mogensen, J. B. & Christensen, Søren Tvorup, 2016, In: Trends in Biochemical Sciences. 41, 9, p. 784-797 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

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