Ivana Novak

Ivana Novak

Professor

ORCID: 0000-0002-8917-8010

Publication year:
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1 - 50 out of 141Page size: 50
  1. 2024
  2. Published

    Editorial overview: New and revitalized old targets in metabolic disease

    Hansen, Jacob B. & Novak, Ivana, 2024, In: Current Opinion in Pharmacology. 75, 3 p., 102434.

    Research output: Contribution to journal › Editorial › Research › peer-review

  3. Published

    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer

    Magni, Lara, Yu, Haoran, Christensen, Nynne, Poulsen, Mette Homann, Frueh, A., Deshar, Ganga, Johansen, A. Z., Johansen, Julia Sidenius, Pless, Stephan, Jørgensen, Niklas Rye & Novak, Ivana, 2024, In: Cancer Cell International. 24, 1, 16 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Imaging of extracellular and intracellular ATP in pancreatic beta cells reveals correlation between glucose metabolism and purinergic signalling

    Ghiasi, S. M., Christensen, Nynne, Pedersen, Per Amstrup, Skovhøj, Emil Zeng & Novak, Ivana, 2024, In: Cellular Signalling. 117, 12 p., 111109.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2023
  6. Published

    An insulin hypersecretion phenotype precedes pancreatic β cell failure in MODY3 patient-specific cells

    Hermann, F. M., Kjærgaard, M. F., Tian, C., Tiemann, Ulf, Jackson, Abigail Laura, Olsen, L. R., Kraft, M., Carlsson, P. O., Elfving, I. M., Kettunen, J. L. T., Tuomi, T., Novak, Ivana & Semb, Tor Henrik, 2023, In: Cell Stem Cell. 30, 1, p. 38-51.e8 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Synergistic effects of agonists and two-pore-domain potassium channels on secretory responses of human pancreatic duct cells Capan-1

    Sørensen, Christiane Elisabeth, Trauzold, A., Christensen, Nynne, Tawfik, D., Szczepanowski, M. & Novak, Ivana, 2023, In: Pflügers Archiv - European Journal of Physiology. 475, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2022
  9. Published

    ATP signaling in pancreatic cancer: the P2X7 receptor

    Magni, Lara, Bouazzi, R., Christensen, Nynne, Tozzi, M., Poulsen, M., Johansen, J., Pless, Stephan & Novak, Ivana, 2022, In: Acta Physiologica. 236, S725, p. 661-661

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  10. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2021
  12. Published

    The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells

    Magni, Lara, Bouazzi, R., Heredero Olmedilla, H., Petersen, P. S. S., Tozzi, M. & Novak, Ivana, 2021, In: Cells. 10, 8, 20 p., 1928.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2020
  14. Published

    Fundamentals of Bicarbonate Secretion in Epithelia

    Novak, Ivana & Praetorius, J., 2020, Basic Epithelial Ion TransportPrinciples and Function: Ion Channels and Transporters of Epitheliain Health and Disease. Hamilton, K. L. & Devor, D. C. (eds.). 2. ed. Springer, Vol. 1. p. 461-541 (Physiology in Health and Disease).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration

    Tozzi, M., Hansen, Jacob B. & Novak, Ivana, 2020, In: Acta Physiologica. 228, 2, 18 p., e13360.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Proton Pump Inhibitors Reduce Pancreatic Adenocarcinoma Progression by Selectively Targeting H+, K+-ATPases in Pancreatic Cancer and Stellate Cells

    Tozzi, M., Sørensen, Christiane Elisabeth, Magni, Lara, Christensen, Nynne, Bouazzi, R., Buch, C. M., Stefanini, M., Duranti, C., Arcangeli, A. & Novak, Ivana, 2020, In: Cancers. 12, 3, 22 p., 640.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Purinergic Signaling in Pancreas - From Physiology to Therapeutic Strategies in Pancreatic Cancer

    Novak, Ivana, Yu, Haoran, Magni, Lara & Deshar, Ganga, 2020, In: International Journal of Molecular Sciences (Online). 21, 22, 21 p., 8781.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    The Vacuolar H+ ATPase α3 Subunit Negatively Regulates Migration and Invasion of Human Pancreatic Ductal Adenocarcinoma Cells

    Flinck, M., Hagelund, S., Gorbatenko, A., Severin, M., Pedraz-Cuesta, E., Novak, Ivana, Stock, C. & Pedersen, Stine Helene Falsig, 2020, In: Cells. 9, 2, 22 p., 465.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Update of P2Y receptor pharmacology: IUPHAR Review 27

    Jacobson, K. A., Delicado, E. G., Gachet, C., Kennedy, C., von Kügelgen, I., Li, B., Miras-Portugal, M. T., Novak, Ivana, Schöneberg, T., Perez-Sen, R., Thor, D., Wu, B., Yang, Z. & Müller, C. E., 2020, In: British Journal of Pharmacology. 177, 11, p. 2413-2433 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. 2019
  21. Published

    Role of the P2X7 receptor in the pathogenesis of type 2 diabetes and its microvascular complications

    Solini, A. & Novak, Ivana, 2019, In: Current Opinion in Pharmacology. 47, p. 75-81 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. 2018
  23. Published

    Deconstructing the principles of ductal network formation in the pancreas

    Dahl-Jensen, Svend Bertel, Yennek, S., Flasse, L., Larsen, Hjalte List, Sever, D., Karremore, G., Novak, Ivana, Sneppen, Kim & Botton, A., 2018, In: PLOS Biology. 16, 7, 25 p., e2002842.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    P2X receptor-ion channels in the inflammatory response in adipose tissue and pancreas-potential triggers in onset of type 2 diabetes?

    Novak, Ivana & Solini, A., 2018, In: Current Opinion in Immunology. 52, p. 1-7 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    The P2X7 receptor and pannexin-1 are involved in glucose-induced autocrine regulation in β-cells

    Tozzi, M., Larsen, A. T., Lange, S. C., Giannuzzo, A., Andersen, M. N. & Novak, Ivana, 2018, In: Scientific Reports. 8, 15 p., 8926.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2017
  27. Published

    Purinergic receptors in adipose tissue as potential targets in metabolic disorders

    Tozzi, M. & Novak, Ivana, 24 Nov 2017, In: Frontiers in Pharmacology. 8, 8 p., 878.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Normal and malignant cells exhibit differential responses to calcium electroporation

    Frandsen, S. K., Krüger, M. B., Mangalanathan, U. M., Tramm, T., Mahmood, F., Novak, Ivana & Gehl, Julie, Aug 2017, In: Cancer Research. 77, 16, p. 4389-4401 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Alternating pH landscapes shape epithelial cancer initiation and progression: focus on pancreatic cancer

    Pedersen, Stine Helene Falsig, Novak, Ivana, Alves, F., Schwab, A. & Pardo, L. A., Jun 2017, In: BioEssays. 39, 6, 10 p., 1600253.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Ion channels in control of pancreatic stellate cell migration

    Storck, H., Hild, B., Schimmelpfennig, S., Sargin, S., Nielsen, N., Zaccagnino, A., Budde, T., Novak, Ivana, Kalthoff, H. & Schwab, A., 3 Jan 2017, In: OncoTarget. 8, 1, p. 769-784 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2016
  32. Published

    ATP signals

    Novak, Ivana, 2016, In: PEN: Science & Technology. 2016, 21, p. 174-174 1 p.

    Research output: Contribution to journal › Comment/debate › Communication

  33. Published

    Difference in membrane repair capacity between cancer cell lines and a normal cell line

    Frandsen, S. K., McNeil, A. K., Novak, Ivana, McNeil, P. L. & Gehl, J., 2016, In: Journal of Membrane Biology. 249, 4, p. 569-576 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Fundamentals of bicarbonate secretion in epithelia

    Novak, Ivana & Prætorius, J., 2016, Ion channels and transporters of epithelia in health and disease. Hamilton, K. L. & Devor, D. C. (eds.). New York, NY: Springer, p. 187-263 77 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  35. Published

    Identification of KCa3.1 channel as a novel regulator of Oxidative phosphorylation in a subset of pancreatic carcinoma cell lines

    Kovalenko, I., Glasauer, A., Schöckel, L., Sauter, D. R. P., Ehrmann, A., Sohler, F., Hägebarth, A., Novak, Ivana & Christian, S., 2016, In: P L o S One. 11, 8, 20 p., e0160658.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    In silico analysis of the transportome in human pancreatic ductal adenocarcinoma

    Zaccagnino, A., Pilarsky, C., Tawfik, D., Sebens, S., Trauzold, A., Novak, Ivana, Schwab, A. & Kalthoff, H., 2016, In: European Biophysics Journal. 45, 7, p. 749-763 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    KCa3.1 (IK) modulates pancreatic cancer cell migration, invasion and proliferation: anomalous effects on TRAM-34

    Bonito, B., Sauter, D. R. P., Schwab, A., Djamgoz, M. B. A. & Novak, Ivana, 2016, In: Pfluegers Archiv. 468, 11, p. 1865-1875 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Monocarboxylate transporters MCT1 and MCT4 regulate migration and invasion of pancreatic ductal adenocarcinoma cells

    Kong, S. C., Nøhr-Nielsen, A., Zeeberg, K., Reshkin, S. J., Hoffmann, E. K., Novak, Ivana & Pedersen, Stine Helene Falsig, 2016, In: Pancreas. 45, 7, p. 1036-1047 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Targeting of the P2X7 receptor in pancreatic cancer and stellate cells

    Giannuzzo, A., Saccomano, M., Napp, J., Ellegaard, M., Alves, F. & Novak, Ivana, 2016, In: International Journal of Cancer. 139, 11, p. 2540-2552 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The adenosine A2B receptor is involved in anion secretion in human pancreatic duct Capan-1 epithelial cells

    Hayashi, M., Inagaki, A., Novak, Ivana & Matsuda, H., 2016, In: Pfluegers Archiv. 468, 7, p. 1171-1181 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    pH-sensitive K+ channel TREK-1 is a novel target in pancreatic cancer

    Sauter, D. R. P., Sørensen, Christiane Elisabeth, Rapedius, M., Brüggemann, A. & Novak, Ivana, 2016, In: B B A - Molecular Basis of Disease. 1862, 10, p. 1994-2003 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2015
  43. Published

    ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)

    Sauter, D. R. P., Novak, Ivana, Pedersen, Stine Helene Falsig, Larsen, Erik Hviid & Hoffmann, E. K., 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1495-1508 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    ATP release, generation and hydrolysis in exocrine pancreatic duct cells

    Kowal, J. M., Yegutkin, G. G. & Novak, Ivana, 2015, In: Purinergic Signalling. 11, 4, p. 533-550 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells

    Kowal, J. M., Haanes, Kristian Agmund, Christensen, Nynne & Novak, Ivana, 2015, In: Cell Communication and Signaling. 13, 16 p., 28 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Fine-tuned ATP signals are acute mediators in osteocyte mechanotransduction

    Kringelbach, T. M., Aslan, D., Novak, Ivana, Ellegaard, M., Syberg, S., Andersen, C. K. B., Kristiansen, K. A., Vang, O., Schwarz, Peter & Jørgensen, N. R., 2015, In: Cellular Signalling. 27, 12, p. 2401-2409 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Proton pump inhibitors inhibit pancreatic secretion: role of gastric and non-gastric H+/K+-ATPases

    Wang, J., Barbuskaite, Dagne, Tozzi, M., Giannuzzo, A., Sørensen, Christiane Elisabeth & Novak, Ivana, 2015, In: PloS one. 10, 5, 20 p., e0126432.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells

    Giannuzzo, A., Pedersen, Stine Helene Falsig & Novak, Ivana, 2015, In: Molecular Cancer. 14, 15 p., 203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2014
  50. Published

    Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential

    Kong, S. C., Giannuzzo, A., Novak, Ivana & Pedersen, Stine Helene Falsig, 2014, In: Biochemistry and Cell Biology. 92, 6, p. 449-459 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Role of vesicular nucleotide transporter VNUT (SLC17A9) in release of ATP from AR42J cells and mouse pancreatic acinar cells

    Haanes, Kristian Agmund, Kowal, J. M., Arpino, G., Lange, S. C., Moriyama, Y., Pedersen, Per Amstrup & Novak, Ivana, 2014, In: Purinergic Signalling. 10, 3, p. 431-440 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    UTP-induced ATP release is a fine-tuned signalling pathway in osteocytes

    Kringelbach, T. M., Aslan, D., Novak, Ivana, Schwarz, Peter & Jørgensen, N. R., 2014, In: Purinergic Signalling. 10, 2, p. 337-347 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2013
  54. Published

    Purinergic regulation of CFTR and Ca2+ -activated Cl- channels and K+ channels in human pancreatic duct epithelium

    Wang, J., Haanes, Kristian Agmund & Novak, Ivana, 1 Apr 2013, In: American Journal of Physiology: Cell Physiology. 304, 7, p. C673-84 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Acid-base transport in pancreas-new challenges

    Novak, Ivana, Haanes, Kristian Agmund & Wang, J., 2013, In: Frontiers in Physiology. 4, 7 p., 380.

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    Cell volume regulation in epithelial physiology and cancer

    Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Novak, Ivana, 2013, In: Frontiers in Physiology. 4, 12 p., 233.

    Research output: Contribution to journal › Review › Research › peer-review

  57. Published

    Ion Transport in Human Pancreatic Duct Epithelium, Capan-1 Cells, Is Regulated by Secretin, VIP, Acetylcholine, and Purinergic Receptors

    Wang, J. & Novak, Ivana, 2013, In: Pancreas. 42, 3, p. 452-460 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Molecular basis of potassium channels in pancreatic duct epithelial cells

    Hayashi, M. & Novak, Ivana, 2013, In: Channels (Austin). 7, 6, p. 432-441 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges

    Bomholtz, Sofia Hammami, Willumsen, N. J., Meinild, A., Klærke, Dan Arne & Novak, Ivana, 2013, In: Acta Physiologica (Print). 207, 3, p. 503-515 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Purinergic signalling and diabetes

    Burnstock, G. & Novak, Ivana, 2013, In: Purinergic Signalling. 9, 3, p. 307-324 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    The cystic fibrosis of exocrine pancreas

    Wilschanski, M. & Novak, Ivana, 2013, In: Cold Spring Harbor Perspectives in Medicine. 3, 5, p. 1-17 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. 2012
  63. Published

    An intermediate-conductance Ca2+-activated K+ channel is important for secretion in pancreatic duct cells

    Hayashi, M., Wang, J., Hede, S. E. & Novak, Ivana, 2012, In: American Journal of Physiology: Cell Physiology. 303, 2, p. C151-C159 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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