Cell Biology and Physiology

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  1. Published

    Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer

    Magni, Lara, Yu, Haoran, Christensen, Nynne, Poulsen, Mette Homann, Frueh, A., Deshar, Ganga, Johansen, A. Z., Johansen, Julia Sidenius, Pless, Stephan, Jørgensen, Niklas Rye & Novak, Ivana, 2024, In: Cancer Cell International. 24, 1, 16 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Role of ATP and P2X7 receptor in pancreatic cancer

    Magni, Lara, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 151 p.

    Research output: Book/Report › Ph.D. thesis › Research

  3. Published

    The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells

    Magni, Lara, Bouazzi, R., Heredero Olmedilla, H., Petersen, P. S. S., Tozzi, M. & Novak, Ivana, 2021, In: Cells. 10, 8, 20 p., 1928.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

    Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    GSK3 is a negative regulator of the thermogenic program in brown adipocytes

    Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Lipolysis regulates major transcriptional programs in brown adipocytes

    Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas

    Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Patient-specific three-dimensional explant spheroids derived from human nasal airway epithelium: a simple methodological approach for ex vivo studies of primary ciliary dyskinesia

    Marthin, J. K., Stevens, E. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Nielsen, Kim G., 23 Mar 2017, In: Cilia. 6, 9 p., 3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Intracellular pH gradients in migrating cells

    Martin, C., Pedersen, Stine Helene Falsig, Schwab, A. & Stock, C., 2011, In: American Journal of Physiology: Cell Physiology. 300, 3, p. C490-C495 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

    Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes

    Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Inhibition of allostimulated HLA-DQ and DP-specific T cells by staphylococcal enterotoxin A

    Masewicz, S., Ledbetter, J. A., Martin, P., Mickelson, E., Hansen, J. A. & Ødum, Niels, 1993, In: Human Immunology. 36, 3, p. 142-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation

    Mathiasen, D. P., Egebjerg, C., Andersen, S. H., Rafn, B., Puustinen, P., Khanna, A., Daugaard, M., Valo, E., Tuomela, S., Bøttzauw, T., Nielsen, Christian Friberg, Willumsen, Berthe Marie, Hautaniemi, S., Lahesmaa, R., Westermarck, J., Jäättelä, M. & Kallunki, T., 2012, In: Oncogene. 31, p. 390-401 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes

    Maurer, J., Zhao, X., Irmler, M., Gudiksen, Anders, Pilmark, N. S., Li, Q., Goj, T., Beckers, J., Hrabě De Angelis, M., Birkenfeld, A. L., Peter, A., Lehmann, R., Pilegaard, Henriette, Karstoft, Kristian, Xu, G. & Weigert, C., 2023, In: American Journal of Physiology: Cell Physiology. 325, 4, p. C1131-C1143 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism

    McLaughlin, K., Acreman, S., Nawaz, S., Cutteridge, J., Clark, A., Knudsen, Jakob Grunnet, Denwood, G., Spigelman, A. F., Fox, J. E. M., Singh, S. P., MacDonald, P. E., Hastoy, B. & Zhang, Q., 2022, In: Diabetic Medicine. 39, 12, 13 p., e14984.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells

    Meng, Signe, Sørensen, E. E., Ponniah, M., Thorlacius-Ussing, J., Crouigneau, R., Larsen, T., Borre, M. T., Willumsen, N., Flinck, M. & Pedersen, Stine Helene Falsig, 2024, In: Journal of Cell Science. 137, 8, 15 p., jcs261608.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Ceramide-induced TCR up-regulation

    Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

    Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5

    Merklinger, L., Bauer, J., Pedersen, Per Amstrup, Damgaard, R. B. & Morth, J. P., 2022, In: Life Science Alliance. 5, 8, 13 p., e202101309.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients

    Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Intake of farmed Atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

    Midtbø, L. K., Ibrahim, M. M., Myrmel, L. S., Aune, U. L., Alvheim, A. R., Liland, N. S., Torstensen, B. E., Rosenlund, G., Liaset, B., Brattelid, T., Kristiansen, Karsten & Madsen, L., 2013, In: P L o S One. 8, 1, 11 p., e53094.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Primary cilia as dynamic and diverse signalling hubs in development and disease

    Mill, P., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2023, In: Nature Reviews. Genetics. 24, 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Effect of cytochalasins on F-actin and morphology of Ehrlich ascites tumor cells.

    Mills, J. W., Pedersen, Stine Helene Falsig, Walmod, P. S. & Hoffmann, E. K., 2000, In: Experimental Cell Research. 261, 1, p. 209-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism

    Miranda, M. Z., Bialik, J. F., Speight, P., Dan, Q., Yeung, T., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2017, In: Journal of Biological Chemistry. 292, 36, p. 14902-14920 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    ATP Production in Chlamydomonas reinhardtii Flagella by Glycolytic Enzymes

    Mitchell, B. F., Pedersen, Lotte Bang, Feely, M., Rosenbaum, J. L. & Mitchell, D. R., 2005, In: Molecular Biology of the Cell. 16, 10, p. 4509-18 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

    Miyake, K., Mickley, L., Litman, Thomas, Zhan, Z., Robey, R., Cristensen, B., Brangi, M., Greenberger, L., Dean, M., Fojo, T. & Bates, S. E., 1 Jan 1999, In: Cancer Research. 59, 1, p. 8-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Characterization of membrane protein trafficking and cellular signaling at the primary cilium: implications for cardiomyogenesis

    Mogensen, J. B., 2016, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  29. Published

    Purification and initial characterization of Plasmodium falciparum K+ channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae

    Molbaek, K., Tejada, M., Ricke, C. H., Scharff-Poulsen, P., Ellekvist, P., Helix-Nielsen, C., Kumar, N., Klærke, Dan Arne & Pedersen, Per Amstrup, 2020, In: Microbial Cell Factories. 19, 1, 183.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Homologous desensitisation of the mouse leukotriene B4 receptor involves protein kinase C-mediated phosphorylation of serine 127.

    Mollerup, J., Eriksen, H. N., Albertsen, J., Wulff, T., Lambert, Ian Henry & Hoffmann, E. K., 2007, In: Cellular Physiology and Biochemistry. 20, 1-4, p. 143-56 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    DNA polymorphism of HLA class II genes in pauciarticular juvenile rheumatoid arthritis

    Morling, Niels, Friis, J., Fugger, L., Georgsen, J., Heilmann, C., Pedersen, F. K., Ødum, Niels & Svejgaard, A., 1991, In: HLA. 38, 1, p. 16-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    DNA polymorphism of HLA class II genes in primary biliary cirrhosis

    Morling, Niels, Dalhoff, K., Fugger, L., Georgsen, J., Jakobsen, B., Ranek, L., Ødum, Niels & Svejgaard, A., 1992, In: Immunogenetics. 35, 2, p. 112-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Evidence of two distinct functionally specialized fibroblast lineages in breast stroma

    Morsing, M., Klitgaard, M. C., Jafari Kermani, Abbas, Villadsen, René, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2016, In: Breast Cancer Research (Online). 18, 11 p., 108.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Fibroblasts direct differentiation of human breast epithelial progenitors

    Morsing, M., Kim, Jiyoung, Villadsen, René, Goldhammer, N., Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2020, In: Breast Cancer Research. 22, 16 p., 102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Possible link between FSH and RANKL release from adipocytes in men with impaired gonadal function including Klinefelter syndrome

    Mortensen, L. J., Lorenzen, M., Jørgensen, N., Andersson, A., Nielsen, J. E., Petersen, L. I., Lanske, B., Juul, Anders, Hansen, Jacob B. & Jensen, M. B., 2019, In: Bone. 123, p. 103-114

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Analysis of caveolin in primary cilia

    Morthorst, Stine Kjær, Mogensen, J. B., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2020, Caveolae: Methods and Protocols. Blouin, C. M. (ed.). Humana Press, p. 27-41 (Methods in Molecular Biology, Vol. 2169).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  37. Published

    Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

    Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2018, In: F E B S Journal. 285, 24, p. 4535-4564

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Regulation of vesicle trafficking at the primary cilium

    Morthorst, Stine Kjær, 2018, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  39. Published

    Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling

    Morthorst, Stine Kjær, Nielsen, C., Farinelli, P., Anvarian, Zeinab, Rasmussen, C. B. R., Serra-Marques, A., Grigoriev, I., Altelaar, M., Fürstenberg, N., Ludwig, A., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2022, In: Journal of Cell Science. 135, 12, 10 p., jcs259471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The intraflagellar transport machinery in ciliary signaling

    Mourão, A., Christensen, Søren Tvorup & Lorentzen, E., 2016, In: Current Opinion in Structural Biology. 41, p. 98-108 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    HLA-DP antigens in patients with chronic autoimmune thrombocytopenia (AITP)

    Mueller-Eckhardt, G., Pawelec, G., Haas, R., Otto, C., Kiefel, V., Ødum, Niels & Mueller-Eckhardt, C., 1989, In: HLA. 34, 2, p. 121-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Characterization of Hailey-Hailey Disease-mutants in presence and absence of wild type SPCA1 using Saccharomyces cerevisiae as model organism

    Muncanovic, D., Justesen, M. H., Preisler, Sarah Spruce & Pedersen, Per Amstrup, 2019, In: Scientific Reports. 9, 25 p., 12442.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

    Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The impact of calmodulin on the cell cycle analyzed in a novel human cellular genetic system

    Munk, M., Alcalde, J., Lorentzen, Lasse Gøbel, Villalobo, A., Berchtold, Martin Werner & Panina, S., 2020, In: Cell Calcium. 88, 8 p., 102207.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Differential expression of the three independent CaM genes coding for an identical protein: Potential relevance of distinct mRNA stability by different codon usage

    Munk, M., Villalobo, E., Villalobo, A. & Berchtold, Martin Werner, 2022, In: Cell Calcium. 107, 20 p., 102656.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Gene duplications and losses among vertebrate deoxyribonucleoside kinases of the non-TK1 Family

    Mutahir, Z., Christiansen, L. S., Clausen, A. R., Berchtold, Martin Werner, Gojkovic, Z., Munch-Petersen, B., Knecht, W. & Piškur, J., 2016, In: Nucleosides, Nucleotides and Nucleic Acids. 35, 10-12, p. 677-690 14 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  47. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Extreme freeze-tolerance in cryophilic tardigrades relies on controlled ice formation but does not involve significant change in transcription: [Corrigendum]

    Møbjerg, A., Kodama, M., Ramos Madrigal, Jazmin, Neves, R. C., Jørgensen, Aslak, Schiøtt, M., Gilbert, M Thomas P & Møbjerg, Nadja, 2022, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 271, 8 p., 111245.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Morphology of the Nephron in the mesonephros of Bufo bufo (Amphibia, Anura, Bufonidae)

    Møbjerg, Nadja, Larsen, Erik Hviid & Jespersen, Å., 1 Jan 1998, In: Acta Zoologica. 79, 1, p. 31-50 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Ongoing revision of Echiniscoididae (Heterotardigrada: Echiniscoidea), with the description of a new interstitial species and genus with unique anal structures

    Møbjerg, Nadja, Jørgensen, Aslak & Kristensen, Reinhardt Møbjerg, 2020, In: Zoological Journal of the Linnean Society . 188, 3, p. 663-680 18 p., zlz122.

    Research output: Contribution to journal › Journal article › Research › peer-review

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