Cell Biology and Physiology

  1. Published

    Dynamic localization of the Na+-HCO3- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia

    Severin, M., Pedersen, E. L., Borre, M. T., Axholm, I., Christiansen, F. B., Ponniah, M., Czaplinska, D., Larsen, T., Pardo, L. A. & Pedersen, Stine Helene Falsig, 2023, In: Journal of Cell Science. 136, 7, 20 p., jcs260687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The enormous repetitive Antarctic krill genome reveals environmental adaptations and population insights

    Shao, C., Sun, S., Liu, K., Wang, J., Li, S., Liu, Q., Deagle, B. E., Seim, I., Biscontin, A., Wang, Q., Liu, X., Kawaguchi, S., Liu, Y., Jarman, S., Wang, Y., Wang, H. Y., Huang, G., Hu, J., Feng, B., De Pittà, C. & 29 others, Liu, S., Wang, R., Ma, K., Ying, Y., Sales, G., Sun, T., Wang, X., Zhang, Y., Zhao, Y., Pan, S., Hao, X., Wang, Y., Xu, J., Yue, B., Sun, Y., Zhang, H., Xu, M., Liu, Y., Jia, X., Zhu, J., Liu, S., Ruan, J., KU, thw266, Yang, H., Xu, X., Wang, J., Zhao, X., Meyer, B. & Fan, G., 2023, In: Cell. 186, 6, p. 1279-1294.e19 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis

    Shen, J. X., Couchet, M., Dufau, J., de Castro Barbosa, T., Ulbrich, M. H., Helmstädter, M., Kemas, A. M., Zandi Shafagh, R., Marques, M., Hansen, Jacob B., Mejhert, N., Langin, D., Rydén, M. & Lauschke, V. M., 2021, In: Advanced Science. 8, 16, 17 p., 2100106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The FASTQ+ format and PISA

    Shi, Quan, Liu, S., Kristiansen, Karsten & Liu, L., 2022, In: Bioinformatics. 38, 19, p. 4639-4642 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

    Sigurðsson, H. H., Olesen, C. W., Dybboe, R., Lauritzen, G. & Pedersen, Stine Helene Falsig, 2015, In: Molecular Cancer Research. 13, 1, p. 63-77 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pharmacological Nature of the Purinergic P2Y Receptor Subtypes That Participate in the Blood Pressure Changes Produced by ADPβS in Rats

    Silva-Velasco, R. C., Villanueva-Castillo, B., Haanes, Kristian Agmund, MaassenVanDenBrink, A. & Villalón, C. M., 2023, In: Pharmaceuticals. 16, 12, 19 p., 1683.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism

    Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published

    Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

    Skjørringe, T., Pedersen, Per Amstrup, Thorborg, S. S., Nissen, P., Gourdon, Pontus Emanuel & Møller, L. B., 7 Apr 2017, In: Scientific Reports. 7, 18 p., 757.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Activation of Stat-3 is involved in the induction of apoptosis after ligation of major histocompatibility complex class I molecules on human Jurkat T cells

    Skov, S., Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, 10, p. 3566-73 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    MHC class I signaling in T cells leads to tyrosine kinase activity and PLC-gamma 1 phosphorylation

    Skov, S., Ødum, Niels & Claesson, Mogens Helweg, 1995, In: Journal of Immunology. 154, 3, p. 1167-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells

    Skov, S., Bonyhadi, M., Ødum, Niels & Ledbetter, J. A., 2000, In: Journal of Immunology. 164, 7, p. 3500-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B

    Skov, Søren, Pedersen, M. T., Andresen, Lars, Straten, P. T., Woetmann, Anders & Ødum, Niels, 2005, In: Cancer Research. 65, 23, p. 11136-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Combined speed endurance and endurance exercise amplify the exercise-induced PGC-1α and PDK4 mRNA response in trained human muscle

    Skovgaard, C., Brandt, N., Pilegaard, Henriette & Bangsbo, Jens, 2016, In: Physiological Reports. 4, 14, 14 p., e12864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Role of the P2X7 receptor in the pathogenesis of type 2 diabetes and its microvascular complications

    Solini, A. & Novak, Ivana, 2019, In: Current Opinion in Pharmacology. 47, p. 75-81 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

    Sommer, V. H., Clemmensen, O. J., Nielsen, O., Wasik, M., Lovato, P., Brender, C., Eriksen, K. W., Woetmann, Anders , Kaestel, C. G., Nissen, Mogens Holst, Ropke, C., Skov, Søren & Ødum, Niels, 2004, In: Leukemia. 18, 7, p. 1288-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Analysis of SOX2 expression in developing human testis and germ cell neoplasia

    Sonne, Si Brask, Perrett, R. M., Nielsen, J. E., Baxter, M. A., Kristensen, D. M., Leffers, H., Hanley, N. A. & Rajpert-De-Meyts, E., 2010, In: International Journal of Developmental Biology. 54, 4, p. 755-760

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Optimizing Staining Protocols for Laser Microdissection of Specific Cell Types from the Testis Including Carcinoma In Situ

    Sonne, Si Brask, Dalgaard, M. D., Nielsen, J. E., Hoei-Hansen, C. E., Rajpert-De Meyts, E., Gjerdrum, L. M. & Leffers, H., 2009, In: PLoS ONE. 4, 5, p. e5536

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Fatty acid composition in organs.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  20. Published

    Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours

    Sonne, Si Brask, Herlihy, A. S., Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Marks, A., Leffers, H. & Rajpert-De Meyts, E., 2006, In: Virchows Archiv. 449, 2, p. 200-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Fatty acid composition in red blood cells.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  22. Published

    Fatty acid composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  23. Published

    Testicular dysgenesis syndrome and the origin of carcinoma in situ testis

    Sonne, Si Brask, Kristensen, D. M., Novotny, G. W., Olesen, I. A., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 2008, In: International Journal of Andrology. 31, 2, p. 275-87 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Do environmental factors play a role in the aetiology of carcinoma in situ testis and the testicular dysgenesis syndrome?

    Sonne, Si Brask, Hoei-Hansen, C. E., Fisher, J. S., Leffers, H., Rajpert-de Meyts, E. & Skakkebæk, Niels Erik, 2004, In: Verhandlungen der Deutschen Gesellschaft fur Pathologie. 88, p. 144-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression

    Sonne, Si Brask, Yadav, R., Yin, G., Dalgaard, M. D., Myrmel, L. S., Gupta, R., Wang, J., Madsen, L., Kajimura, S. & Kristiansen, Karsten, 2017, In: Adipocyte. 6, 2, p. 124-133 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Macronutrient composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  27. Published

    The ABA/LANCL1/2 Hormone/Receptor System Controls Adipocyte Browning and Energy Expenditure

    Spinelli, S., Cossu, V., Passalacqua, M., Hansen, Jacob B., Guida, L., Magnone, M., Sambuceti, G., Marini, C., Sturla, L. & Zocchi, E., 2023, In: International Journal of Molecular Sciences. 24, 4, 27 p., 3489.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans

    Stattin, E., Wiklund, F., Lindblom, K., Onnerfjord, P., Jonsson, B., Tegner, Y., Sasaki, T., Struglics, A., Lohmander, S., Dahl, N., Heinegård, D. & Aspberg, A., 2010, In: American Journal of Human Genetics. 86, 2, p. 126-37 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells

    Stein, U., Lage, H., Jordan, A., Walther, W., Bates, S. E., Litman, Thomas, Hohenberger, P. & Dietel, M., 20 Feb 2002, In: International journal of cancer. Journal international du cancer. 97, 6, p. 751-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Differential expression of cell adhesion genes: implications for drug resistance

    Stein, W. D., Litman, Thomas, Fojo, T. & Bates, S. E., 1 Mar 2005, In: International journal of cancer. Journal international du cancer. 113, 6, p. 861-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Data on the recurrence of breast tumors fit a model in which dormant cells are subject to slow attrition but can randomly awaken to become malignant

    Stein, W. D. & Litman, Thomas, 2006, In: Cell Cycle. 5, 20, p. 2348-53 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published

    CSPP-L and EB3 localize to centriolar satellites and are required for satellite-dependent recruitment of ciliopathy proteins to the centrosome

    Sternemalm, J., Geimer, S., Aarnes, E. K., Frikstad, K. M., Stokke, T., Pedersen, Lotte Bang & Patzke, S., 2015, In: Cilia. 4, Suppl. 1, 1 p., P76.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  34. Published

    Ciliary Localization of the Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis

    Stevens, E. M., Vladar, E. K., Alanin, M. C., Christensen, Søren Tvorup, von Buchwald, Christian & Milla, C., Jan 2020, In: American Journal of Respiratory Cell and Molecular Biology. 62, 1, p. 120-123 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Roles of pH and the Na+/H+ exchanger NHE1 in cancer: from cell biology and animal models to an emerging translational perspective?

    Stock, C. & Pedersen, Stine Helene Falsig, Apr 2017, In: Seminars in Cancer Biology. 43, p. 5-16 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    p21-ras effector domain mutants constructed by "cassette" mutagenesis.

    Stone, J. C., Vass, W. C., Willumsen, Berthe Marie & Lowy, D. R., 1988, In: Molecular and Cellular Biology. 8, 8, p. 3565-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Ion channels in control of pancreatic stellate cell migration

    Storck, H., Hild, B., Schimmelpfennig, S., Sargin, S., Nielsen, N., Zaccagnino, A., Budde, T., Novak, Ivana, Kalthoff, H. & Schwab, A., 3 Jan 2017, In: OncoTarget. 8, 1, p. 769-784 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A unifying mechanism for Cancer cell death through ion channel activation by HAMLET

    Storm, P., Klausen, T. K., Trulsson, M., Ho CS, J., Dosnon, M., Westergren, T., Chao, Y., Rydström, A., Yang, H., Pedersen, Stine Helene Falsig & Svanborg, C., 2013, In: P L o S One. 8, 3, 18 p., e58578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effects of protein kinase C activators and staurosporine on protein kinase activity, cell survival, and proliferation in Tetrahymena thermophila.

    Straarup, E., Schousboe, P., Hansen, H., Kristiansen, K., Hoffmann, E. K., Rasmussen, L. & Christensen, Søren Tvorup, 1997, In: Microbios. 91, 368-369, p. 181-90

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    TASK-2 AND ACTIVATION OF HUMAN T-CELLS

    Strøm, P. D., Kirkegaard, S. S. & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1302-1303 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  41. Published

    Swelling-activated ion channels: functional regulation in cell-swelling, proliferation and apoptosis.

    Stutzin, A. & Hoffmann, E. K., 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 27-42 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Mitigating Cyanide Poisoning

    Suman, S. G., Gretarsdottir, J. M., Lambert, Ian Henry & Stürup, Stefan, Jul 2017, p. S261-S261.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  43. Published

    Deconstructing transcriptional variations and their effects on immunomodulatory function among human mesenchymal stromal cells

    Sun, C., Zhang, K., Yue, J., Meng, S. & Zhang, X., 2021, In: Stem Cell Research & Therapy. 12, 16 p., 53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

    Sun, C., Wang, H., Ma, Q., Chen, C., Yue, J., Li, B. & Zhang, X., 2021, In: Cell and Bioscience. 11, 12 p., 24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Time-dependent regulation of hepatic cytochrome P450 mRNA in male liver-specific PGC-1α knockout mice

    Sundekilde, U. K., Kristensen, C. M., Olsen, M. A., Pilegaard, Henriette & Rasmussen, M. K., 2022, In: Toxicology. 469, 8 p., 153121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    How protons pave the way to aggressive cancers

    Swietach, P., Boedtkjer, E. & Pedersen, Stine Helene Falsig, 2023, In: Nature Reviews Cancer. 23, p. 825-841 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation

    Szabo, R., Uzzun Sales, K., Kosa, P., Shylo, N. A., Godiksen, S., Hansen, K. K., Friis, S., Gutkind, J. S., Vogel, Lotte, Hummler, E., Camerer, E. & Bugge, T. H., 2012, In: PLoS Genetics. 8, 8, 17 p., e1002937.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor

    Sønder, S. U. S., Woetmann, Anders , Ødum, Niels & Bendtzen, K., 2006, In: Apoptosis. 11, 12, p. 2159-65 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors

    Søndergaard, H., Frederiksen, K. S., Thygesen, P., Galsgaard, E. D., Skak, K., Kristjansen, P. E. G., Ødum, Niels & Kragh, M., 2007, In: Cancer Immunology, Immunotherapy. 56, 9, p. 1417-28 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review