Cell Biology and Physiology

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  1. 2021
  2. Published

    Taxonomic Description and Genome Sequence of Christensenella intestinihominis sp. nov., a Novel Cholesterol-Lowering Bacterium Isolated From Human Gut

    Zou, Y., Xue, W., Lin, X., Hu, T., Liu, S., Sun, C., Luo, G., Lv, M., Dai, Y., Kristiansen, Karsten & Xiao, L., 2021, In: Frontiers in Microbiology. 12, 13 p., 632361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer

    Pedersen, Stine Helene Falsig, Flinck, M. & Pardo, L. A., 2021, In: International Journal of Molecular Sciences. 22, 10, 27 p., 5209.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells

    Magni, Lara, Bouazzi, R., Heredero Olmedilla, H., Petersen, P. S. S., Tozzi, M. & Novak, Ivana, 2021, In: Cells. 10, 8, 20 p., 1928.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells

    Doray, A., Lemoine, R., Severin, M., Chadet, S., Lopez-Charcas, O., Héraud, A., Baron, C., Besson, P., Monteil, A., Pedersen, Stine Helene Falsig & Roger, S., 2021, In: Cells. 10, 7, 15 p., 1624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The heart arrhythmia-linked D130G calmodulin mutation causes premature inhibitory autophosphorylation of CaMKII

    Berchtold, Martin Werner, Munk, M., Kulej, K., Porth, I., Lorentzen, Lasse Gøbel, Panina, S., Zacharias, T., Larsen, M. R. & la Cour, J. M., 2021, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1868, 12, 9 p., 119119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

    Sun, C., Wang, H., Ma, Q., Chen, C., Yue, J., Li, B. & Zhang, X., 2021, In: Cell and Bioscience. 11, 12 p., 24.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment

    Fontenete, S., Lerche, Catharina Margrethe, Paasch, U., Perez-Moreno, Mirna, Olesen, U. H. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2022
  10. Published

    3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines

    Frikstad, K. M., Schink, K. O., Gilani, S., Pedersen, Lotte Bang & Patzke, S., 2022, In: Bio-protocol. 12, 6, 14 p., 4360.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Ex vivo Release of Calcitonin Gene-Related Peptide from the Trigeminovascular System in Rodents

    Rasmussen, R. H., Jansen-Olesen, I., Kristensen, D. M. & Christensen, S. L., 2022, In: Journal of Visualized Experiments. 183, 19 p., e63723.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    In Vitro Characterization of a Threonine-Ligated Molybdenyl-Sulfide Cluster as a Putative Cyanide Poisoning Antidote: Intracellular Distribution, Effects on Organic Osmolyte Homeostasis, and Induction of Cell Death

    Gretarsdottir, J. M., Lambert, Ian Henry, Stürup, Stefan & Suman, S. G., 2022, In: ACS Pharmacology and Translational Science. 5, 10, p. 907–918

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Setaphyes algarvensis sp. nov., the first description of an allomalorhagid mud dragon (Kinorhyncha: Allomalorhagida) from Portugal (Eastern Atlantic Ocean)

    Gonzalez-Casarrubios, A., Cepeda, D., Pardos, F., Neves, R. C. & Sanchez, N., 2022, In: European Journal of Taxonomy. 821, p. 150-165 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A Bacterial Genome and Culture Collection of Gut Microbial in Weanling Piglet

    Dong, B., Lin, X., Jing, X., Hu, T., Zhou, J., Chen, J., Xiao, L., Wang, B., Chen, Z., Liu, J., Hu, Y., Liu, G., Liu, S., Liu, J., Wei, W. & Zou, Y., 2022, In: Microbiology Spectrum. 10, 1, 13 p., e02417-21.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling

    Alphonse, N., Wanford, J. J., Voak, A. A., Gay, J., Venkhaya, S., Burroughs, O., Mathew, S., Lee, T., Evans, S. L., Zhao, W., Frowde, K., Alrehaili, A., Dickenson, R. E., Munk, M., Panina, S., Mahmood, I. F., Llorian, M., Stanifer, M. L., Boulant, S., Berchtold, M. W. & 4 others, Bergeron, J. R. C., Wack, A., Lesser, C. F. & Odendall, C., 2022, In: Cell. 185, 13, p. 2354-2369.e17

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    ATP signaling in pancreatic cancer: the P2X7 receptor

    Magni, Lara, Bouazzi, R., Christensen, Nynne, Tozzi, M., Poulsen, M., Johansen, J., Pless, Stephan & Novak, Ivana, 2022, In: Acta Physiologica. 236, S725, p. 661-661

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  17. Published

    Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferation and Migration through Ca2+ Entry and Interaction with PI3K/CaM

    Schnipper, J., Kouba, S., Hague, F., Girault, A., Telliez, M., Guenin, S., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: Cancers. 14, 19, 27 p., 4946.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Ameliorating effects of lifelong physical activity on healthy aging and mitochondrial function in human white adipose tissue

    Gudiksen, Anders, Qoqaj, A., Jørgensen, Stine Ringholm, Wojtaszewski, Jørgen F P, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2022, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 77, 6, p. 1101-1111 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs

    Alvarez-Dominguez, J. R., Winther, Sally, Hansen, Jacob B., Lodish, H. F. & Knoll, M., 2022, In: iScience. 25, 1, 25 p., 103680.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling

    Morthorst, Stine Kjær, Nielsen, C., Farinelli, P., Anvarian, Zeinab, Rasmussen, C. B. R., Serra-Marques, A., Grigoriev, I., Altelaar, M., Fürstenberg, N., Ludwig, A., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2022, In: Journal of Cell Science. 135, 12, 10 p., jcs259471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Beta2-agonist increases skeletal muscle interleukin 6 production and release in response to resistance exercise in men

    Hostrup, Morten, Knudsen, Jakob Grunnet, Maag Kristensen, C., Jessen, Søren Kaare, Pilegaard, Henriette & Bangsbo, Jens, 2022, In: Scandinavian Journal of Medicine & Science in Sports. 32, 7, p. 1099-1108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Cell transcriptomic atlas of the non-human primate Macaca fascicularis

    Han, L., Wei, X., Liu, C., Volpe, G., Zhuang, Z., Zou, X., Wang, Z., Pan, T., Yuan, Y., Zhang, X., Fan, P., Guo, P., Lai, Y., Lei, Y., Liu, X., Yu, F., Shangguan, S., Lai, G., Deng, Q., Liu, Y. & 57 others, Wu, L., Shi, Quan, Yu, H., Huang, Y., Cheng, M., Xu, J., Liu, Y., Wang, M., Wang, C., Zhang, Y., Xie, D., Yang, Y., Yu, Y., Zheng, H., Wei, Y., Huang, F., Lei, J., Huang, W., Zhu, Z., Lu, H., Wang, B., Wei, X., Chen, F., Yang, T., Du, W., Chen, J., Xu, S., An, J., Ward, C., Wang, Z., Pei, Z., Wong, C., Liu, X., Zhang, H., Liu, M., Qin, B., Schambach, A., Isern, J., Feng, L., Liu, Y., Guo, X., Liu, Z., Sun, Q., Maxwell, P. H., Barker, N., Muñoz-Cánoves, P., Gu, Y., Mulder, J., Uhlen, M., Tan, T., Liu, S., Yang, H., Wang, J., Hou, Y., Xu, X., Esteban, M. A. & Liu, L., 2022, In: Nature. 604, p. 723-731

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor

    La Cour, S. H., Juhler, K., Kogelman, L. J. A., Olesen, Jes, Klærke, Dan Arne, Kristensen, D. M. & Jansen-Olesen, I., 2022, In: Journal of Headache and Pain. 23, 12 p., 59.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Could Experimental Inflammation Provide Better Understanding of Migraines?

    Reducha, Philip Victor, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: Cells. 11, 15, 17 p., 2444.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Differential expression of the three independent CaM genes coding for an identical protein: Potential relevance of distinct mRNA stability by different codon usage

    Munk, M., Villalobo, E., Villalobo, A. & Berchtold, Martin Werner, 2022, In: Cell Calcium. 107, 20 p., 102656.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Differential expression profiling of heat stressed tardigrades reveals major shift in the transcriptome

    Neves, R. C., Møbjerg, A., Kodama, M., Ramos Madrigal, Jazmin, Gilbert, M Thomas P & Møbjerg, Nadja, 2022, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 267, 7 p., 111169.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Distribution of protoporphyrin IX in erythrocytes in a case of acquired erythropoietic protoporphyria

    Heerfordt, I. M., Fontenete, S., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 37, 3 p., 102629.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Dual action of the cannabinoid receptor 1 ligand arachidonyl-2′-chloroethylamide on calcitonin gene-related peptide release

    Christiansen, I. M., Edvinsson, J. C. A., Reducha, Philip Victor, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: Journal of Headache and Pain. 23, 11 p., 30.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature

    Kohler, Katharina Theresa, Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René & Kim, Jiyoung, 2022, In: npj Breast Cancer. 8, 1, 12 p., 81.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Effect of perfluoroalkyl exposure in pregnancy and infancy on intrauterine and childhood growth and anthropometry. Sub study from COPSAC2010 birth cohort

    Sevelsted, A., Gürdeniz, G., Rago, D., Pedersen, C. T., Lasky-Su, J. A., Checa, A., Zhang, P., Wheelock, C. E., Normann, S. S., Kristensen, D. M., Rasmussen, Morten Arendt, Schullehner, J., Sdougkou, K., Martin, J. W., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2022, In: EBioMedicine. 83, 12 p., 104236.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Entanglement in a qubit-qubit-tardigrade system

    Lee, K. S., Tan, Y. P., Nguyen, L. H., Budoyo, R. P., Park, K. H., Hufnagel, C., Yap, Y. S., Møbjerg, Nadja, Vedral, V., Paterek, T. & Dumke, R., 2022, In: New Journal of Physics. 24, 13 p., 123024.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Extreme freeze-tolerance in cryophilic tardigrades relies on controlled ice formation but does not involve significant change in transcription: [Corrigendum]

    Møbjerg, A., Kodama, M., Ramos Madrigal, Jazmin, Neves, R. C., Jørgensen, Aslak, Schiøtt, M., Gilbert, M Thomas P & Møbjerg, Nadja, 2022, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 271, 8 p., 111245.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans

    Plomgaard, Peter Stendahl, Hansen, J. S., Townsend, L. K., Gudiksen, Anders, Secher, Niels H., Clemmesen, J. O., Støving, R. K., Goetze, Jens P. , Wright, D. C. & Pilegaard, Henriette, 2022, In: Frontiers in Endocrinology. 13, 1037948.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression

    Elingaard-Larsen, L. O., Rolver, M. G., Sørensen, E. E. & Pedersen, Stine Helene Falsig, 2022, From Malignant Transformation to Metastasis: Ion Transport in Tumor Biology. Stock, C. & Pardo, L. A. (eds.). Springer, p. 1-38 38 p. (Reviews of Physiology, Biochemistry and Pharmacology, Vol. 182).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  35. Published

    Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism

    Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Hypothesis: Metformin is a potential reproductive toxicant

    Tavlo, M., Skakkebæk, Niels Erik, Mathiesen, Elisabeth, Kristensen, D. M., Kjær, Kurt H., Andersson, A. & Lindahl-Jacobsen, R., 2022, In: Frontiers in Endocrinology. 13, 8 p., 1000872.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Isolation and Crystallization of the D156C Form of Optogenetic ChR2

    Zhang, L., Wang, Kaituo, Ning, S., Pedersen, Per Amstrup, Duelli, A. S. & Gourdon, Pontus Emanuel, 2022, In: Cells. 11, 5, 11 p., 895.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system: expression, release and interactions with 5-HT1 receptors

    Edvinsson, J. C. A., Maddahi, A., Christiansen, I. M., Reducha, Philip Victor, Warfvinge, K., Sheykhzade, Majid, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: The Journal of Headache and Pain. 23, 19 p., 26.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Lipolysis regulates major transcriptional programs in brown adipocytes

    Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism

    McLaughlin, K., Acreman, S., Nawaz, S., Cutteridge, J., Clark, A., Knudsen, Jakob Grunnet, Denwood, G., Spigelman, A. F., Fox, J. E. M., Singh, S. P., MacDonald, P. E., Hastoy, B. & Zhang, Q., 2022, In: Diabetic Medicine. 39, 12, 13 p., e14984.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Massively targeted evaluation of therapeutic CRISPR off-targets in cells

    Pan, X., Qu, K., Yuan, H., Xiang, X., Anthon, C., Pashkova, L., Liang, X., Han, P., Corsi, G. I., Xu, F., Liu, P., Zhong, J., Zhou, Y., Ma, T., Jiang, H., Liu, J., Wang, J., Jessen, N., Bolund, L., Yang, H. & 5 others, Xu, X., Church, G. M., Gorodkin, Jan, Lin, L. & Luo, Y., 2022, In: Nature Communications. 13, 14 p., 4049.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation

    Goldhammer, N., Kim, Jiyoung, Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2022, In: Communications Biology . 5, 1, 13 p., 219.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Novel Sequencing Approaches for the High-Throughput Identification of Full-length Poly(A) RNA Transcripts at the Single-cell Level

    XIE, Z., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 88 p.

    Research output: Book/Report › Ph.D. thesis › Research

  44. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Paracetamol Use During Pregnancy - A Call for Precautionary Action

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2022, In: Obstetrical and Gynecological Survey. 77, 3, p. 133-134 2 p.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Peter Satir (1936-2022), cell biology pioneer and mentor

    Sale, W. S. & Christensen, Søren Tvorup, 2022, In: Journal of Cell Science. 135, 23

    Research output: Contribution to journal › Comment/debate › Research

  47. Published

    Phase I study of adjuvant immunotherapy with autologous tumor-infiltrating lymphocytes in locally advanced cervical cancer

    Huang, H., Nie, C-P., Liu, X., Song, B., Yue, J., Xu, J., He, J., Li, K., Feng, Y., Wan, T., Zheng, M., Zhang, Y-N., Ye, W-J., Li, J-D., Li, Y-F., Li, J., Cao, X-P., Liu, Z., Zhang, X., Liu, Q. & 3 others, Zhang, X., Liu, J. & Li, J., 2022, In: Journal of Clinical Investigation. 132, 15, 15 p., e157726.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5

    Merklinger, L., Bauer, J., Pedersen, Per Amstrup, Damgaard, R. B. & Morth, J. P., 2022, In: Life Science Alliance. 5, 8, 13 p., e202101309.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Production of an Active, Human Membrane Protein in Saccharomyces cerevisiae: Full-Length FICD

    Virolainen, M. S., Søltoft, C. L., Pedersen, Per Amstrup & Ellgaard, Lars, 2022, In: International Journal of Molecular Sciences. 23, 5, 17 p., 2458.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Reply to ‘Paracetamol use in pregnancy — caution over causal inference from available data’; ‘Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy’

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., M. Andrade, A., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 3, p. 192 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  51. Published

    Reply to ‘Paracetamol use in pregnancy — neglecting context promotes misinterpretation’

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 1 p., 386.

    Research output: Contribution to journal › Letter › Research › peer-review

  52. Published

    Role of ATP and P2X7 receptor in pancreatic cancer

    Magni, Lara, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 151 p.

    Research output: Book/Report › Ph.D. thesis › Research

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