Cell Biology and Physiology

  1. 2010
  2. Published

    The primary cilium at a glance

    Satir, P., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2010, In: Journal of Cell Science. 123, Pt 4, p. 499-503 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Vitamin D controls T cell antigen receptor signaling and activation of human T cells

    von Essen, Marina Rode, Kongsbak-Wismann, Martin, Schjerling, Peter, Ølgaard, Klaus, Ødum, Niels & Geisler, Carsten, 2010, In: Nature Immunology. 11, 4, p. 344-349 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Immunoflourescence and mRNA analysis of human embryonic stem cells (hESCs) grown under feeder-free conditions

    Awan, A., Oliveri, R. S., Jensen, P. L., Christensen, Søren Tvorup & tcg964, tcg964, 1 Jan 2010, In: Methods in Molecular Biology. 584, p. 195-210 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pinpointing differences in cisplatin-induced apoptosis in adherent and non-adherent cancer cells

    Tastesen, H. S., Holm, J. B., Poulsen, K. A., Møller, C., Stürup, Stefan, Hoffmann, E. K. & Lambert, Ian Henry, 1 Jan 2010, In: Cellular Physiology and Biochemistry. 26, 6, p. 809-820 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Role of BK channels in the apoptotic volume decrease in native eel intestinal cells

    Lionetto, M. G., Giordano, M. E., Calisi, A., Caricato, R., Hoffmann, E. & Schettino, T., 1 Jan 2010, In: Cellular Physiology and Biochemistry. 25, 6, p. 733-44 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

    Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Prolactin and oestrogen synergistically regulate gene expression and proliferation of breast cancer cells

    Rasmussen, L. M., Frederiksen, K. S., Din, N., Galsgaard, E., Christensen, L., Berchtold, Martin Werner & Panina, S., 16 Aug 2010, In: Endocrine - Related Cancer. 17, 3, p. 809-822

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Monovalent ions control proliferation of Ehrlich Lettre ascites cells

    Klausen, T. K., Preisler, S., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 1 Sep 2010, In: American Journal of Physiology (Consolidated). 299, 3, p. C714-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance

    Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Activation of the TASK-2 channel after cell swelling is dependent on tyrosine phosphorylation

    Kirkegaard, S. S., Lambert, Ian Henry, Gammeltoft, S. & Hoffmann, E. K., 1 Oct 2010, In: American Journal of Physiology (Consolidated). 299, 4, p. C844-53

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Ion transport proteins control pancreatic ductal adenocarcinoma

    Schwab, A., Stock, C., Swietach, P., Hulikova, A., Vaughan-Jones, R., Pedersen, S. H. F., Andersen, A. D., Hoffmann, E., Novak, I., Reshkin, S., Prevarskaya, N., Lemonnier, L., A-S, B., Fraser, S. P., Arcangeli, A., Zanieri, F., D'Amico, M., Kalthoff, H., Djamgoz, M. B., Alves, F. & 2 others, Pardo, L. & Stuehmer, W., 1 Oct 2010, In: Onkologie. 33, Suppl. 6, p. 269 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Programmed cell death-10 enhances proliferation and protects malignant T cells from apoptosis

    Lauenborg, B., Kopp, K., Krejsgaard, T., Eriksen, K. W., Geisler, Carsten, Dabelsteen, Sally, Gniadecki, R., Zhang, Q., Wasik, M. A., Woetmann, Anders & Odum, N., 1 Oct 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 10, p. 719-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Acute cholesterol depletion leads to net loss of the organic osmolyte taurine in Ehrlich Lettré tumor cells

    Villumsen, Kasper Rømer, Duelund, L. & Lambert, Ian Henry, 1 Nov 2010, In: Amino Acids. 39, 5, p. 1521-36 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    COX-2 is a novel target in therapy of mycosis fungoides

    Kopp, K. L. M., Dabelsteen, Sally, Krejsgaard, T., Eriksen, K. W., Geisler, Carsten, Becker, J. C., Wasik, M., Ødum, Niels & Danielsen, A. L. W., 1 Dec 2010, In: Leukemia. 24, 12, p. 2127-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Stability, accumulation and cytotoxicity of an albumin-cisplatin adduct

    Møller, C., Tastesen, H. S., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 1 Dec 2010, In: Metallomics. 2, 12, p. 811-818 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2011
  18. Published

    Pseudomonas aeruginosa and Saccharomyces cerevisiae biofilm in flow cells

    Weiss Nielsen, M., Sternberg, C., Molin, S. & Regenberg, Birgitte, 2011, In: Journal of Visualized Experiments. 47, p. pii:2383

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cell Volume Regulation and Signaling in 3T3-L1 Pre-adipocytes and Adipocytes: on the Possible Roles of Caveolae, Insulin Receptors, FAK and ERK1/2

    Eduardsen, K., Larsen, S., Novak, Ivana, Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1231-46 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Characterization of an ex vivo femoral head model assessed by markers of bone and cartilage turnover

    Madsen, S. H., Goettrup, A. S., Thomsen, G., Christensen, Søren Tvorup, Schultz, N., Henriksen, K., Bay-Jensen, A. & Karsdal, M. A., 2011, In: Cartilage. 2, 3, p. 265-278 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

    Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Litman, Thomas, Woetmann, Anders , Glue, C., Røpke, M. A., Skov, Lone & Ødum, Niels, 2011, In: Blood. 118, 22, p. 5891-5900 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Differential role for ERK2 in anoxia-induced activation of transcription and translation of Hsp70 in NIH 3T3 cells

    Ossum, C., Lauritsen, A. N., Karottki, D. G. & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 27, 2, p. 109-120 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

    Schrøder, J. M., Larsen, J., Komarova, Y., Akhmanova, A., Thorsteinsson, R. I., Grigoriev, I., Manguso, R., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Geimer, S. & Pedersen, Lotte Bang, 2011, In: Journal of Cell Science. 124, p. 2539-51 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Fatty acid composition in organs.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  25. Published

    Fatty acid composition in red blood cells.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  26. Published

    Fatty acid composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  27. Published

    Function and oligomerization of various TMEM16 members

    Hoffmann, E. K. & Holm, Niels B.; Jacobsen, Kari S.; Zeeberg, Katrine , H. N. B. ;. J. K. S. ;. Z. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1300-1300 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. Published

    Glucocorticoids exert context-dependent effects on cells of the joint in vitro

    Madsen, S. H., Andreassen, K. V., Christensen, Søren Tvorup, Karsdal, M. A., Sverdrup, F. M., Bay-Jensen, A. & Henriksen, K., 2011, In: Steroids. 76, 13, p. 1474-82 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Hyperosmotic stress strongly potentiates serum response factor (SRF)-dependent transcriptional activity in ehrlich lettré ascites cells through a mechanism involving p38 mitogen-activated protein kinase

    Gorbatenko, A., Wiwel, M., Klingberg, H., Nielsen, A. B., Kapus, A. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Cellular Physiology. 226, 11, p. 2857-2868 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    In human granulosa cells from small antral follicles, androgen receptor mRNA and androgen levels in follicular fluid correlate with FSH receptor mRNA

    Nielsen, M. E., Rasmussen, I. A., Kristensen, S. G., Christensen, Søren Tvorup, Møllgård, Kjeld, Andersen, Elisabeth Anne Wreford, Byskov, A. G. S. & tcg964, tcg964, 2011, In: Molecular Human Reproduction. 17, 1, p. 63-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Intracellular pH gradients in migrating cells

    Martin, C., Pedersen, Stine Helene Falsig, Schwab, A. & Stock, C., 2011, In: American Journal of Physiology: Cell Physiology. 300, 3, p. C490-C495 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Ion Channels Involved in Cell Volume Regulation: Effects on Migration, Proliferation, and Programmed Cell Death in Non Adherent EAT Cells and Adherent ELA Cells

    Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1061-78 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Macronutrient composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  34. Published

    Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway

    Krejsgaard, T. F., Ralfkiær, U., Clasen-Linde, E., Eriksen, K. W. K., Kopp, K. L. M., Bonefeld, Charlotte Menne, Geisler, Carsten, Dabelsteen, Sally, Wasik, M. A., Ralfkiaer, E. M., Woetmann, Anders & Ødum, Niels, 2011, In: Journal of Investigative Dermatology. 131, 6, p. 1331-1338 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Mammary gland stem cells: current status and future challenges

    Fridriksdottir, A. J. R., Petersen, Ole William & Rønnov-Jessen, Lone, 2011, In: International Journal of Developmental Biology. 55, 7-9, p. 719-29 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Mechanisms of gemcitabine-resistance in pancreatic cancer cells

    Rasmussen, L. J. H., Ossum, C. G., Tvingsholm, S., Lambert, Ian Henry & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1321-1322 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  37. Published

    Optimisation of the Factor VIII yield in mammalian cell cultures by reducing the membrane bound fraction

    Kolind, M. P., Nørby, P. L., Berchtold, Martin Werner & Johnsen, L. B., 2011, In: Journal of Biotechnology. 151, 4, p. 357-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Osmosensory mechanisms in cellular and systemic volume regulation

    Pedersen, Stine Helene Falsig, Kapus, A. & Hoffmann, E. K., 2011, In: Journal of the American Society of Nephrology. 22, 9, p. 1587-97 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Possible role of integrins as cell volume regulators in adherent, non-adherent and multidrug resistant Ehrlich cells

    Broberg, B., Aspberg, A. & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1318-1318 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Regulation of taurine homeostasis by protein kinase CK2 in mouse fibroblasts

    Hansen, D. B., Guerra, B., Jacobsen, J. H. & Lambert, Ian Henry, 2011, In: Amino Acids. 40, 4, p. 1091-1106 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Regulation of taurine transport systems by protein kinase CK2 in mammalian cells

    Lambert, Ian Henry & Hansen, D. B., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1099-1110 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Response to Schushan et al.: Two conflicting NHE1 model structures: compatibility with experimental data and implications for the transport mechanism

    Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Biological Chemistry. 286, 21, p. le10 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. Published

    Structural modeling and electron paramagnetic resonance spectroscopy of the human Na+/H+ exchanger isoform 1, NHE1

    Nygaard, E. B., Lagerstedt, J. O., Bjerre, G., Shi, B., Budamagunta, M., Poulsen, K. A., Lundby, S. M., Rigor, R. R., Voss, J. C., Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: The Journal of Biological Chemistry. 286, 1, p. 634-48 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    TASK-2 AND ACTIVATION OF HUMAN T-CELLS

    Strøm, P. D., Kirkegaard, S. S. & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1302-1303 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  45. Published

    TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections

    Hansen, A. K., Regner, M., Bonefeld, Charlotte Menne, Boding, L., Kongsbak-Wismann, Martin, Ødum, Niels, Müllbacher, A., Geisler, Carsten & von Essen, Marina Rode, 2011, In: European Journal of Immunology. 41, 7, p. 1948-1957 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    THE ROLE OF TMEM16F AND TMEM16K IN CELL MIGRATION

    Jacobsen, K. S., Poulsen, K. A., Schwab, A. & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1301-1301 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    TMEM16F-A CA(2+)- ACTIVATED CL- CHANNEL: ROLES IN VOLUME REGULATION, CELL MIGRATION AND APOPTOSIS

    Grubb, S., Poulsen, K. A., Jacobsen, K., Kyed, T., Klausen, T. K., Schwab, A., Larsen, E. H. & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1298-1299 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking

    Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na+/H+ exchanger NHE1

    Andersen, A., Bentzen, Bo Hjorth, Salling, H., Klingberg, H., Kanneworff, M., Grunnet, Morten & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 1, p. 13-24 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The level of claudin-7 is reduced as an early event in colorectal carcinogenesis

    Lange, Jette Bornholdt, Friis, S., Godiksen, S., Poulsen, Steen Seier, Santoni Rugiu, Eric, Bisgaard, Hanne Cathrine, Lothe, I. M. B., Ikdahl, T., Tveit, K. M., Johnson, E., Kure, E. H. & Vogel, Lotte, 2011, In: B M C Cancer. 11, p. 65 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Cell volume homeostatic mechanisms: effectors and signalling pathways

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 27 Jan 2011, In: Acta Physiologica. 202, 3, p. 465–485

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53

    Zandi, R., Selivanova, G., Christensen, C. L., Gerds, Thomas Alexander, Willumsen, Berthe Marie & Poulsen, H. S., 1 May 2011, In: Clinical Cancer Research. 17, 9, p. 2830-2841 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2012
  54. Published

    A fluorescent probe which allows highly specific thiol labeling at low pH

    Nielsen, J. W., Jensen, K. S., Hansen, R. R. E., Gotfredsen, C. H. & Winther, Jakob R., 2012, In: Analytical Biochemistry. 421, 1, p. 115-120 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    A proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins

    Jiang, K., Toedt, G., Gouveia, S. M., Davey, N. E., Hua, S., Vaart, B. V. D., Grigoriev, I., Larsen, J., Pedersen, Lotte Bang, Bezstarosti, K., Lince-Faria, M., Demmers, J., Steinmetz, M. O., Gibson, T. J. & Akhmanova, A., 2012, In: Current biology : CB. 22, 19, p. 1800-1807 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Cartilage oligomeric matrix protein specific antibodies are pathogenic

    Geng, H., Nandakumar, K. S., Pramhed, A., Aspberg, A., Mattsson, R. & Holmdahl, R., 2012, In: Arthritis Research & Therapy. 14, 4, 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Comparison of microRNA expression using different preservation methods of matched psoriatic skin samples

    Løvendorf, M. B., Zibert, J. R., Hagedorn, P. H., Glue, C., Ødum, Niels, Røpke, M. A. & Skov, L., 2012, In: Experimental Dermatology. 21, 4, p. 299-301 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Cytotoxicity of CD56bright NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A

    Nielsen, N., Ødum, Niels, Ursø, B., Lanier, L. L. & Spee, P., 2012, In: PLoS ONE. 7, 2, 10 p., e31959.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Downregulation of the taurine transporter TauT during hypo-osmotic stress in NIH3T3 mouse fibroblasts

    Hansen, D. B., Friis, M. B., Hoffmann, E. K. & Lambert, Ian Henry, 2012, In: Journal of Membrane Biology. 245, 2, p. 77-87 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Expression patterns of the immunosuppressive proteins PD-1/CD279 and PD-L1/CD274 at different stages of cutaneous T-Cell lymphoma/mycosis fungoides

    Kantekure, K., Yang, Y., Raghunath, P., Schaffer, A., Woetmann, Anders , Zhang, Q., Ødum, Niels & Wasik, M., 2012, In: American Journal of Dermatopathology. 34, 1, p. 126-128 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  61. Published

    Gram-scale solution-phase synthesis of selective sodium bicarbonate Co-transport Inhibitor S0859: in vitro efficacy studies in breast cancer cells

    Larsen, A. M., Krogsgaard-Larsen, N., Lauritzen, G., Olesen, C. W., Hansen, S. H., Bødtkjer, E., Pedersen, Stine Helene Falsig & Bunch, Lennart, 2012, In: ChemMedChem. 7, 10, p. 1808-1814 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation

    Mathiasen, D. P., Egebjerg, C., Andersen, S. H., Rafn, B., Puustinen, P., Khanna, A., Daugaard, M., Valo, E., Tuomela, S., Bøttzauw, T., Nielsen, Christian Friberg, Willumsen, Berthe Marie, Hautaniemi, S., Lahesmaa, R., Westermarck, J., Jäättelä, M. & Kallunki, T., 2012, In: Oncogene. 31, p. 390-401 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle

    Madsen, C. P., Klausen, T. K., Fabian, A., Hansen, B. J., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2012, In: American Journal of Physiology: Cell Physiology. 303, 6, p. C625-C634 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy

    Bødtkjer, E., Bunch, Lennart & Pedersen, Stine Helene Falsig, 2012, In: Current Pharmaceutical Design. 18, 10, p. 1345-1371 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Primary cilia and aberrant cell signaling in epithelial ovarian cancer

    Egeberg, D. L., Lethan, M., Manguso, R., Schneider, L., Awan, A., Jørgensen, T. S., Byskov, A. G., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Cilia. 1, 15, 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) signaling

    Christensen, Søren Tvorup, Clement, C. A., Satir, P. & Pedersen, Lotte Bang, 2012, In: Journal of Pathology. 226, 2, p. 172-184 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation

    Szabo, R., Uzzun Sales, K., Kosa, P., Shylo, N. A., Godiksen, S., Hansen, K. K., Friis, S., Gutkind, J. S., Vogel, Lotte, Hummler, E., Camerer, E. & Bugge, T. H., 2012, In: PLoS Genetics. 8, 8, 17 p., e1002937.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Regulating intraflagellar transport

    Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Nature Cell Biology. 14, 9, p. 904-906 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Regulation of the ligand-dependent activation of the epidermal growth factor receptor by calmodulin

    Li, H., Panina, S., Kaur, A., Ruano, M. J., Sánchez-González, P., la Cour, P. J. M., Stephan, A., Olesen, U. H., Berchtold, Martin Werner & Villalobo, A., 2012, In: Journal of Biological Chemistry. 287, 5, p. 3273-3281 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Regulatory T cells and immunodeficiency in mycosis fungoides and Sézary syndrome

    Krejsgaard, T. F., Ødum, Niels, Geisler, Carsten, Wasik, M. A. & Woetmann, Anders , 2012, In: Leukemia. 26, p. 424-432 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Role of ion transport in control of apoptotic cell death

    Lang, F. & Hoffmann, E. K., 2012, Comprehensive physiology. Wiley, p. 2037-2061 25 p. (Comprehensive Physiology; No. 3, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  72. Published

    Significance of calcium binding, tyrosine phosphorylation, and lysine trimethylation for the essential function of calmodulin in vertebrate cells analyzed in a novel gene replacement system

    Panina, S., Stephan, A., la Cour, J. M., Jacobsen, K., Kallerup, L. K., Bumbuleviciute, R., Knudsen, K. V. K., Sanchez-Gonzalez, P., Villalobo, A., Olesen, U. H. & Berchtold, Martin Werner, 2012, In: Journal of Biological Chemistry. 287, 22, p. 18173-18181 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2

    Lauritzen, G., Stock, C., Lemaire, J., Lund, S. F., Jensen, M. F., Damsgaard, B., Petersen, K. S., Wiwel, M., Rønnov-Jessen, Lone, Schwab, A. & Pedersen, Stine Helene Falsig, 2012, In: Cancer Letters. 317, 2, p. 172-183 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    The ciliary cytoskeleton

    Pedersen, Lotte Bang, Schrøder, J. M., Satir, P. & Christensen, Søren Tvorup, 2012, In: Comprehensive Physiology. 2, 1, p. 779-803 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    The different roles of aggrecan interaction domains

    Aspberg, A., 2012, In: Journal of Histochemistry and Cytochemistry. 60, 12, p. 987-996 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity

    Kim, Jiyoung, Villadsen, René, Sørlie, T., Fogh, L., Grønlund, S. Z., Fridriksdóttir, A. J. R., Kuhn, I., Rank, F., Wielenga, V. T., Solvang, H., Edwards, P. A. W., Børresen-Dale, A., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6124-6129 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    FoxP3 mRNA splice forms in synovial CD4+ T cells in rheumatoid arthritis and psoriatic arthritis

    Ryder, L. R., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Bliddal, H., Danneskiold-Samsøe, B., Ribel-Madsen, S. & Ryder, L. P., May 2012, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 120, 5, p. 387-396 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. 2013
  79. Published

    A Matriptase-Prostasin Reciprocal Zymogen Activation Complex with Unique Features: PROSTASIN AS A NON-ENZYMATIC CO-FACTOR FOR MATRIPTASE ACTIVATION

    Friis, S., Uzzun Sales, K., Godiksen, S., Peters, D. E., Lin, C., Vogel, Lotte & Bugge, T. H., 2013, In: The Journal of Biological Chemistry. 288, 26, p. 19028-19039 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    A unifying mechanism for Cancer cell death through ion channel activation by HAMLET

    Storm, P., Klausen, T. K., Trulsson, M., Ho CS, J., Dosnon, M., Westergren, T., Chao, Y., Rydström, A., Yang, H., Pedersen, Stine Helene Falsig & Svanborg, C., 2013, In: P L o S One. 8, 3, 18 p., e58578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex

    la Cour, J. M., Schindler, A. J., Berchtold, Martin Werner & Schekman, R., 2013, In: P L o S One. 8, 9, 8 p., e75309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Analysis of microtubule plus-end-tracking proteins in cilia

    Larsen, J., Grigoriev, I., Akhmanova, A. & Pedersen, Lotte Bang, 2013, Cilia, Part A. Marshall, W. F. (ed.). Elsevier, p. 105-122 18 p. (Methods in Enzymology, Vol. 524).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  83. Published

    Analysis of primary cilia in directional cell migration in fibroblasts

    Christensen, Søren Tvorup, Veland, I., Schwab, A., Cammer, M. & Satir, P., 2013, In: Methods in Enzymology. 525, p. 45-58 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Cell volume regulation in epithelial physiology and cancer

    Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Novak, Ivana, 2013, In: Frontiers in Physiology. 4, 12 p., 233.

    Research output: Contribution to journalReviewResearchpeer-review

  85. Published

    Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    CrossTalk proposal: cell volume changes are an essential step in the cell death machinery

    Lang, F. & Hoffmann, E. K., 2013, In: Journal of Physiology. 591, 24, p. 6119-6121 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  87. Published

    Differential effects of decoy receptor- and antibody-mediated tumour necrosis factor blockage on FoxP3 expression in responsive arthritis patients

    Ryder, L. R., Ryder, L. P., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bliddal, Henning, 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 4, p. 337-347 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo controlled bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown and increased IL-6 release

    Bach, E., Nielsen, R. R., Vendelbo, M., Møller, A. B., Jessen, N., Buhl, M., Hafstrøm, T. K., Holm, L., Pedersen, S. B., Pilegaard, Henriette, Biensøe, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Diabetes. 62, 12, p. 4023-4029

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

    Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

    Ly, D. L., Waheed, F., Lodyga, M., Speight, P., Masszi, A., Nakano, H., Hersom, M. N. S., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2013, In: American Journal of Physiology: Cell Physiology. 304, 2, p. C115-C127 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Intake of farmed Atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

    Midtbø, L. K., Ibrahim, M. M., Myrmel, L. S., Aune, U. L., Alvheim, A. R., Liland, N. S., Torstensen, B. E., Rosenlund, G., Liaset, B., Brattelid, T., Kristiansen, Karsten & Madsen, L., 2013, In: P L o S One. 8, 1, 11 p., e53094.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential

    Pedersen, Stine Helene Falsig & Stock, C., 2013, In: Cancer Research. 73, 6, p. 1658-1661 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Isolation and differentiation of stromal vascular cells to beige/brite cells

    Aune, U. L., Ruiz, L. & Kajimura, S., 2013, In: Journal of Visualized Experiments. 73, e50191.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    KCNK5 in Physiology and Pathophysiology: Focus on Cell Volume Control

    Kirkegaard, S. S., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 120 p.

    Research output: Book/ReportPh.D. thesisResearch

  96. Published

    KCNK5 is functionally down-regulated upon long-term hypotonicity in Ehrlich ascites tumor cells

    Kirkegaard, S. S., Wulff, T., Gammeltoft, S. & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 32, 5, p. 1238-1246 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Primary Cilia, Signaling Networks and Cell Migration

    Veland, I. R., 2013, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  99. Published

    Proteomic analysis of human blastocoel fluid and blastocyst cells

    Jensen, P., Beck, H. C., Petersen, J., Hreinsson, J., Wånggren, K., Laursen, S. B., Sørensen, P. D., Christensen, Søren Tvorup & tcg964, tcg964, 2013, In: Stem Cells and Development. 22, 7, p. 1126-1135 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Quantifying changes in the cellular thiol-disulfide status during differentiation of B cells into antibody-secreting plasma cells

    Hansen, R. R. E., Otsu, M., Braakman, I. & Winther, Jakob R., 2013, In: International Journal of Cell Biology. 2013, 10 p., 898563.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Rebuttal from Florian Lang and Else K. Hoffmann

    Lang, F. & Hoffmann, E. K., 2013, In: Journal of Physiology. 591, 24, p. 6127 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  102. Published

    Reevaluation of the proposed autocrine proliferative function of prolactin in breast cancer

    Nitze, L. M., Galsgaard, E. D., Din, N., Lund, V. L., Rasmussen, B. B., Berchtold, Martin Werner, Christensen, L. & Panina, S., 2013, In: Breast Cancer Research and Treatment. 142, 1, p. 31-44 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Spontaneous metastasis in congenic mice with transgenic breast cancer is unaffected by plasminogen gene ablation

    Almholt, K., Juncker-Jensen, A., Lærum, O. D., Johnsen, M., Rømer, J. & Lund, L. R., 2013, In: Clinical and Experimental Metastasis. 30, 3, p. 277-288 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

    Clement, C. A., Ajbro, K. D., Koefoed, K., Vestergaard, M. L., Veland, I. R., Perestrello Ramos H de Jesus, M., Pedersen, Lotte Bang, Benmerah, A., tcg964, tcg964, Larsen, Lars Allan & Christensen, Søren Tvorup, 2013, In: Cell Reports. 3, 6, p. 1806-1814 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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