Cell Biology and Physiology

  1. Published

    K+, Cl- AND WATER CHANNELS IN REGULATION OF CELL VOLUME AND CELL SURVIVAL

    Hoffmann, E. K., 2009, In: Journal of Physiological Sciences. Suppl. 1, p. 93-93

    Research output: Contribution to journalConference abstract in journalResearch

  2. Published

    KCa3.1 (IK) modulates pancreatic cancer cell migration, invasion and proliferation: anomalous effects on TRAM-34

    Bonito, B., Sauter, D. R. P., Schwab, A., Djamgoz, M. B. A. & Novak, Ivana, 2016, In: Pfluegers Archiv. 468, 11, p. 1865-1875 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    KCNK5 in Physiology and Pathophysiology: Focus on Cell Volume Control

    Kirkegaard, S. S., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 120 p.

    Research output: Book/ReportPh.D. thesisResearch

  4. Published

    KCNK5 is functionally down-regulated upon long-term hypotonicity in Ehrlich ascites tumor cells

    Kirkegaard, S. S., Wulff, T., Gammeltoft, S. & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 32, 5, p. 1238-1246 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.

    Schou, K. B., Mogensen, J. B., Morthorst, Stine Kjær, Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 30 Jan 2017, In: Nature Communications. 8, 15 p., 14177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Kif7 keeps cilia tips in shape

    Pedersen, Lotte Bang & Akhmanova, A., 2014, In: Nature Cell Biology. 16, 7, p. 623-625 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Kinesin-3 motor protein KIF13B localizes to centrosomes and primary cilia and regulates ciliary length and signaling

    Schou, K. B., Mogensen, J. B., Aleliunaite, A., Morthorst, Stine Kjær, Veland, I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., O3.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  8. Published

    Kinesins 1 and 3 Cooperate on the Same Vesicle to Transport Exocytotic Carriers

    Serra-Marques, A., Martin, M., Katrukha, E., Grigoriev, I., Liu, Q., Pedersen, Lotte Bang, Kapitein, L. & Akhmanova, A., 2019, In: Biophysical Journal. 116, 3, Suppl. 1, p. 309a 1526-Plat.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    Kinetic analysis of interleukin 2 (IL-2) production and expression of IL-2 receptors by uraemic and normal lymphocytes

    Langhoff, E., Hofmann, B., Ødum, Niels, Ladefoged, J., Platz, P., Ryder, L. P., Svejgaard, A. & Ødum, Niels, 1987, In: Scandinavian Journal of Immunology. 25, 1, p. 29-36 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Kinetic and Thermodynamic Aspects of Cellular Thiol-Disulfide Redox Regulation

    Jensen, K. S., Hansen, R. E. & Winther, Jakob R., 2009, In: Antioxidants & Redox Signaling. 11, 5, p. 1047-1058

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Kinetics of lactate transport in sarcolemmal giant vesicles obtained from human skeletal muscle

    Juel, C., Kristiansen, S., Pilegaard, Henriette, Wojtaszewski, Jørgen F P & Richter, Erik A., 1994, In: Journal of Applied Physiology. 76, 3, p. 1031-1036 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter

    Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, 4, p. 1137-46 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Lack of skeletal muscle IL-6 affects pyruvate dehydrogenase activity at rest and during prolonged exercise

    Gudiksen, Anders, Schwartz, C. L., Bertholdt, L., Joensen, E., Knudsen, Jakob Grunnet & Pilegaard, Henriette, 2016, In: P L o S One. 11, 6, 17 p., e0156460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Lactate transport studied in sarcolemmal giant vesicles from human muscle biopsies: relation to training status

    Pilegaard, Henriette, Bangsbo, Jens, Richter, Erik A. & Juel, C., 1994, In: Journal of Applied Physiology. 77, 4, p. 1858-1862 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinoma

    Pedersen, T. X., Leethanakul, C., Patel, V., Mitola, D., Lund, L. R., Danø, K., Johnsen, M., Gutkind, J. S. & Bugge, T. H., 2003, In: Oncogene. 22, 25, p. 3964-76 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system: expression, release and interactions with 5-HT1 receptors

    Edvinsson, J. C. A., Maddahi, A., Christiansen, I. M., Reducha, Philip Victor, Warfvinge, K., Sheykhzade, Majid, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: The Journal of Headache and Pain. 23, 19 p., 26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane

    Geisler, Carsten, Dietrich, J., Nielsen, B. L., Kastrup, J., Lauritsen, J. P. H., Ødum, Niels & Bartels, Mette Damkjær, 1998, In: Journal of Biological Chemistry. 273, 33, p. 21316-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle

    Sailani, M. R., Halling, Jens Frey, Møller, H. D., Lee, H., Plomgaard, Peter Stendahl, Pilegaard, Henriette, Snyder, M. P. & Regenberg, Birgitte, 2019, In: Scientific Reports. 9, p. 1-11 3272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling

    Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Lipolysis regulates major transcriptional programs in brown adipocytes

    Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs

    Teilmann, S. C. & Christensen, Søren Tvorup, 2005, In: Cell Biology International. 29, 5, p. 340-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma

    Witkiewicz, A., Raghunath, P., Wasik, A., Junkins-Hopkins, J. M., Jones, D., Zhang, Q., Ødum, Niels & Wasik, M. A., 2007, In: Human Pathology. 38, 3, p. 462-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism

    McLaughlin, K., Acreman, S., Nawaz, S., Cutteridge, J., Clark, A., Knudsen, Jakob Grunnet, Denwood, G., Spigelman, A. F., Fox, J. E. M., Singh, S. P., MacDonald, P. E., Hastoy, B. & Zhang, Q., 2022, In: Diabetic Medicine. 39, 12, 13 p., e14984.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients

    Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair

    Schreml, S., Meier, R. J., Kirschbaum, M., Kong, S. C., Gehmert, S., Felthaus, O., Kuechler, S., Sharpe, J. R., Woeltje, K., Weiss, K. T., Albert, M., Seidl, U., Schroeder, J., Morsczeck, C., Prantl, L., Duschl, C., Pedersen, S. H. F., Gosau, M., Berneburg, M., Wolfbeis, O. S. & 2 others, Landthaler, M. & Babilas, P., 2014, In: Theranostics. 4, 7, p. 721-735 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Lymph Vessels Associate with Cancer Stem Cells from Initiation to Malignant Stages of Squamous Cell Carcinoma

    Cazzola, Anna, Calzón Lozano, D., Menne, D. H., Dávila Pedrera, R., Liu, J., Peña-Jiménez, D., Fontenete, S., Halin, C. & Perez-Moreno, Mirna, 2023, In: International Journal of Molecular Sciences. 24, 17, 20 p., 13615.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo

    Peña-Jimenez, D., Fontenete, S., Megias, D., Fustero-Torre, C., Graña-Castro, O., Castellana, D., Loewe, R. & Perez-Moreno, Mirna, 2019, In: EMBO Journal. 38, 19, 17 p., e101688.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Lymphocyte transformation response to pokeweed mitogen as a predictive marker for development of AIDS and AIDS related symptoms in homosexual men with HIV antibodies

    Hofmann, B., Lindhardt, B. O., Gerstoft, J., Petersen, C. S., Platz, P., Ryder, L. P., Ødum, Niels, Dickmeiss, E., Nielsen, P. B. & Ullman, S., 1987, In: British medical journal (Clinical research ed.). 295, 6593, p. 293-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism

    Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, Marie Sophie, Markussen, L. K., Viuff, B. M., Lambert, Ian Henry, Hansen, Jacob B. & Pedersen, Stine Helene Falsig, 12 Oct 2017, In: Scientific Reports. 7, 1, 13 p., 13101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells

    Meng, Signe, Sørensen, E. E., Ponniah, M., Thorlacius-Ussing, J., Crouigneau, R., Larsen, T., Borre, M. T., Willumsen, N., Flinck, M. & Pedersen, Stine Helene Falsig, 2024, In: Journal of Cell Science. 137, 8, 15 p., jcs261608.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    MHC class I signaling in T cells leads to tyrosine kinase activity and PLC-gamma 1 phosphorylation

    Skov, S., Ødum, Niels & Claesson, Mogens Helweg, 1995, In: Journal of Immunology. 154, 3, p. 1167-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors

    Ødum, Niels, Kanner, S. B., Ledbetter, J. A. & Svejgaard, A., 1993, In: Journal of Immunology. 150, 12, p. 5289-98 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    MHC class II molecules regulate growth in human T cells

    Nielsen, M., Ødum, Niels, Bendtzen, K., Ryder, L. P., Jakobsen, B. K. & Svejgaard, A., 1994, In: Experimental and Clinical Immunogenetics. 11, 1, p. 23-32 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Macronutrient composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  37. Published

    Malignant T cells exhibit CD45 resistant Stat 3 activation and proliferation in cutaneous T cell lymphoma.

    Krejsgaard, T., Helvad, R., Ralfkiær, E., Astvad, K., Grønbæk, K., Eriksen, K., Geisler, C., Kopp, K. L. M., Zhang, Q., Ødum, Niels, Woetmann, Anders , Katharina, K., Wasik, M., Odum, N. & Woetmann, A., 2010, In: The Open Leukemia Journal. 3, p. 9-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Malignant T cells exhibit CD45 resistant Stat3 activation and proliferation in cutaneous

    Krejsgaard, T. F., Helvad, R., Ralfkiaer, E., Astvad, K., Grønbæk, K., Eriksen, K. W., Geisler, C., Kopp, K. L. M., Zhang, Q., Ødum, Niels & Woetmann, Anders , 2010, In: The Open Leukemia Journal. 3, p. 9-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome

    Krejsgaard, T., Gjerdrum, L. M., Ralfkiaer, E., Lauenborg, B., Eriksen, K. W., Mathiesen, A., Bovin, L. F., Gniadecki, R., Geisler, Carsten, Ryder, L. P., Zhang, Q., Wasik, M. A., Ødum, Niels & Woetmann, Anders , 2008, In: Leukemia. p. 2230-2239 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway

    Krejsgaard, T. F., Ralfkiær, U., Clasen-Linde, E., Eriksen, K. W. K., Kopp, K. L. M., Bonefeld, Charlotte Menne, Geisler, Carsten, Dabelsteen, Sally, Wasik, M. A., Ralfkiaer, E. M., Woetmann, Anders & Ødum, Niels, 2011, In: Journal of Investigative Dermatology. 131, 6, p. 1331-1338 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Mammary gland stem cells: current status and future challenges

    Fridriksdottir, A. J. R., Petersen, Ole William & Rønnov-Jessen, Lone, 2011, In: International Journal of Developmental Biology. 55, 7-9, p. 719-29 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression

    Lauritsen, J. P. H., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Nielsen, M. W., Rasmussen, A. B., Ødum, Niels, Dietrich, J. & Geisler, Carsten, 2004, In: Traffic - International Journal of Intracellular Transport. 5, 9, p. 672-84 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Massively targeted evaluation of therapeutic CRISPR off-targets in cells

    Pan, X., Qu, K., Yuan, H., Xiang, X., Anthon, C., Pashkova, L., Liang, X., Han, P., Corsi, G. I., Xu, F., Liu, P., Zhong, J., Zhou, Y., Ma, T., Jiang, H., Liu, J., Wang, J., Jessen, N., Bolund, L., Yang, H. & 5 others, Xu, X., Church, G. M., Gorodkin, Jan, Lin, L. & Luo, Y., 2022, In: Nature Communications. 13, 14 p., 4049.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Mechanisms Regulating Acid-Base Transporter Expression in Breast- and Pancreatic Cancer: Contributions to the Cancer Phenotype

    Gorbatenko, A., 2015, Department of Biology, Faculty of Science, University of Copenhagen. 180 p.

    Research output: Book/ReportPh.D. thesisResearch

  45. Published

    Mechanisms Underlying Profibrotic Epithelial Phenotype and Epithelial-Mesenchymal Crosstalk

    Bialik, J. F., 2017, Department of Biology, Faculty of Science, University of Copenhagen. 182 p.

    Research output: Book/ReportPh.D. thesisResearch

  46. Published

    Mechanisms of activation of NHE by cell shrinkage and by calyculin A in Ehrlich ascites tumor cells.

    Pedersen, Stine Helene Falsig, Varming, C., Christensen, Søren Tvorup & Hoffmann, E. K., 2002, In: Journal of Membrane Biology. 189, 1, p. 67-81 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Mechanisms of gemcitabine-resistance in pancreatic cancer cells

    Rasmussen, L. J. H., Ossum, C. G., Tvingsholm, S., Lambert, Ian Henry & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1321-1322 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    Mechanisms of irreversible aquaporin-10 inhibition by organogold compounds studied by combined biophysical methods and atomistic simulations

    Pimpão, C., Wragg, D., Bonsignore, R., Aikman, B., Pedersen, Per Amstrup, Leoni, S., Soveral, G. & Casini, A., 2021, In: Metallomics. 13, 9, 11 p., mfab053.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Metabolic regulation of glucagon secretion

    Armour, Sarah Louise, Stanley, J. E., Cantley, J., Dean, E. D. & Knudsen, Jakob Grunnet, 2023, In: The Journal of endocrinology. 259, 1, 15 p., e230081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Metabolic reprogramming by driver mutation-tumor microenvironment interplay in pancreatic cancer: new therapeutic targets

    Andersen, Henriette Berg, Ialchina, Renata, Pedersen, Stine Helene Falsig & Czaplinska, D., 2021, In: Cancer and Metastasis Reviews. 40, 4, p. 1093-1114 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

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