Cell Biology and Physiology

  1. Published

    RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.

    Carton, I., Trouet, D., Hermans, D., Barth, H., Aktories, K., Droogmans, G., Jorgensen, N. K., Hoffmann, E. K., Nilius, B. & Eggermont, J., 2002, In: American Journal of Physiology: Cell Physiology. 283, 1, p. C115-C125

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Rodent behavior following a dural inflammation model with anti-CGRP migraine medication treatment

    Reducha, Philip Victor, Bömers, J. P., Edvinsson, L. & Haanes, Kristian Agmund, 2023, In: Frontiers in Neurology. 14, 13 p., 1082176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Role of ATP and P2X7 receptor in pancreatic cancer

    Magni, Lara, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 151 p.

    Research output: Book/ReportPh.D. thesisResearch

  4. Published

    Role of BK channels in the apoptotic volume decrease in native eel intestinal cells

    Lionetto, M. G., Giordano, M. E., Calisi, A., Caricato, R., Hoffmann, E. & Schettino, T., 1 Jan 2010, In: Cellular Physiology and Biochemistry. 25, 6, p. 733-44 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Role of H+,K+ -ATPase and pH-sensitive K2P channels in pancreatic cancer

    Deshar, Ganga, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 114 p.

    Research output: Book/ReportPh.D. thesisResearch

  6. Published

    Role of ion transport in control of apoptotic cell death

    Lang, F. & Hoffmann, E. K., 2012, Comprehensive physiology. Wiley, p. 2037-2061 25 p. (Comprehensive Physiology; No. 3, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. Published

    Role of phospholipase A2 in the induction of drip loss in porcine muscle.

    Poulsen, K. A., Young, J. F., Theil, P., Kolko, Miriam, Oksbjerg, N. & Lambert, Ian Henry, 2007, In: Journal of Agricultural and Food Chemistry. 55, 5, p. 1970-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Role of phylogenetically conserved amino acids in folding of Na,K-ATPase

    Jørgensen, J. R. & Pedersen, Per Amstrup, 19 Jun 2001, In: Biochemistry. 40, 24, p. 7301-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Role of the P2X7 receptor in the pathogenesis of type 2 diabetes and its microvascular complications

    Solini, A. & Novak, Ivana, 2019, In: Current Opinion in Pharmacology. 47, p. 75-81 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance

    Hoffmann, E. K., Sørensen, B. H., Sauter, D. R. P. & Lambert, Ian Henry, 2015, In: Channels (Austin). 9, 6, p. 380-396 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts.

    Rentsch, M. L., Ossum, C. G., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: Pflügers Archiv: European Journal of Physiology. 454, 4, p. 649-62 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment

    Andersen, Anne Poder, Flinck, M., Oernbo, E. K., Pedersen, N. B., Viuff, B. M. & Pedersen, Stine Helene Falsig, 2016, In: Molecular Cancer. 15, 18 p., 45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Roles of pH and the Na+/H+ exchanger NHE1 in cancer: from cell biology and animal models to an emerging translational perspective?

    Stock, C. & Pedersen, Stine Helene Falsig, Apr 2017, In: Seminars in Cancer Biology. 43, p. 5-16 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Roles of pH in control of cell proliferation

    Flinck, M., Kramer, S. H. & Pedersen, Stine Helene Falsig, 2018, In: Acta Physiologica. 223, 3, p. 1-17 e13068.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts.

    Pedersen, Stine Helene Falsig, Poulsen, K. A. & Lambert, Ian Henry, 2006, In: American Journal of Physiology: Cell Physiology. 291, 6, p. C 1286-1296

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Roles of the cytoskeleton and of Protein Phosphorylation Events in the Osmotic Stress Response in EEL Intestinal Epithelium

    Lionetto, M. G., Pedersen, Stine Helene Falsig, Hoffmann, E. K., Giordano, M. E. & Schettino, T., 2002, In: Cellular Physiology and Biochemistry. 12, 4, p. 163-178 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    SHP2 regulates IL-2 induced MAPK activation, but not Stat3 or Stat5 tyrosine phosphorylation, in cutaneous T cell lymphoma cells

    Lundin Brockdorff, J., Woetmann, Anders , Mustelin, T., Kaltoft, K., Zhang, Q., Wasik, M. A., Röpke, C. & Ødum, Niels, 2002, In: Cytokine. 20, 4, p. 141-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function

    Brender, C., Columbus, R., Metcalf, D., Handman, E., Starr, R., Huntington, N., Tarlinton, D., Ødum, Niels, Nicholson, S. E., Nicola, N. A., Hilton, D. J. & Alexander, W. S., 2004, In: Molecular and Cellular Biology. 24, 13, p. 6094-103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides

    Fredholm, S., Gjerdrum, Lise Mette Rahbek, Willerslev-Olsen, A., Petersen, D. L., Nielsen, I. Ø., Kauczok, C., Wobser, M., Ralfkiaer, U., Bonefeld, Charlotte Menne, Wasik, M. A., Krejsgaard, T., Geisler, Carsten, Ralfkiaer, E., Gniadecki, R., Woetmann, Anders & Ødum, Niels, 2014, In: Anticancer Research. 34, 10, p. 5277-5286 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

    Zhang, Q., Wang, H. Y., Woetmann, Anders , Raghunath, P. N., Ødum, Niels & Wasik, M. A., 2006, In: Blood. 108, 3, p. 1058-64 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

    Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Selective modulation of the CD4 molecular complex by Pseudomonas aeruginosa alkaline protease and elastase

    Pedersen, Bente Klarlund, Kharazmi, A., Theander, Thor Grundtvig, Ødum, Niels, Andersen, V. & Bendtzen, K., 1987, In: Scandinavian Journal of Immunology. 26, 1, p. 91-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Sensors and signal transduction pathways in vertebrate cell volume regulation.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: Contributions to Nephrology. 152, p. 54-104 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Sensory cilia and integration of signal transduction in human health and disease.

    Christensen, Søren Tvorup, Pedersen, Lotte Bang, Schneider, L. & Satir, P., 2007, In: Traffic - International Journal of Intracellular Transport. 8, 2, p. 97-109 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure

    Chen, W., Weng, Z., Xie, Z., Xie, Y., Zhang, C., Chen, Z., Ruan, F., Wang, J., Sun, Y., Fang, Y., Guo, M., Tong, Y., Li, Y. & Tang, C., 2021, In: Epigenetics & Chromatin. 14, 11 p., 40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Serological identification of neoantigens on mouse fibroblasts which have undergone "spontaneous" malignant alteration in vitro.

    Willumsen, Berthe Marie, Ulrich, K. & Kieler, J., 1979, In: International Journal of Cancer. 23, 2, p. 209-16 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson’s disease

    Ferreira, S. A., Li, Conghui, Klæstrup, I. H., Vitic, Z., Rasmussen, R. K., Kirkegaard, A., Toft, G. U., Betzer, C., Svendsen, P., Jensen, P. H., Luo, Y., Etzerodt, A., Moestrup, S. K. & Romero-Ramos, M., 2023, In: npj Parkinson's Disease. 9, 1, 21 p., 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: American Journal of Physiology: Cell Physiology. 292, 5, p. C1854-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase

    Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    Signal transduction by HLA class II antigens expressed on activated T cells

    Ødum, Niels, Martin, P. J., Schieven, G. L., Hansen, J. A. & Ledbetter, J. A., 1991, In: European Journal of Immunology. 21, 1, p. 123-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Signal transduction by HLA class II molecules in human T cells: induction of LFA-1-dependent and independent adhesion

    Ødum, Niels, Yoshizumi, H., Okamoto, Y., Kamikawaji, N., Kimura, A., Nishimura, Y. & Sasazuki, T., 1992, In: Human Immunology. 35, 2, p. 71-84 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Signal transduction by HLA-DR is mediated by tyrosine kinase(s) and regulated by CD45 in activated T cells

    Ødum, Niels, Martin, P. J., Schieven, G. L., Norris, N. A., Grosmaire, L. S., Hansen, J. A. & Ledbetter, J. A., 1991, In: Human Immunology. 32, 2, p. 85-94 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Significance of calcium binding, tyrosine phosphorylation, and lysine trimethylation for the essential function of calmodulin in vertebrate cells analyzed in a novel gene replacement system

    Panina, S., Stephan, A., la Cour, J. M., Jacobsen, K., Kallerup, L. K., Bumbuleviciute, R., Knudsen, K. V. K., Sanchez-Gonzalez, P., Villalobo, A., Olesen, U. H. & Berchtold, Martin Werner, 2012, In: Journal of Biological Chemistry. 287, 22, p. 18173-18181 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

    Klausen, T. K., Janssens, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig & Nilius, B., 2014, In: Cell Calcium. 55, 1, p. 38-47 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Single-Channel Recordings of K+ Channels Expressed in Saccharomyces Cerevisiae

    Tejada, M. D. L. A., Molbaek, K., Cazimi, H., Ellekvist, P., Callø, Kirstine, Nielsen, C. H., Pedersen, Per Amstrup & Klærke, Dan Arne, 2017, In: Biophysical Journal. 112, 3, Suppl. 1, p. 406A 1 p., 2002-Pos Board B322.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  36. Published

    Skeletal Muscle Interleukin-6 Regulates Hepatic Cytochrome P450 Expression: Effects of 16-Week High-Fat Diet and Exercise

    Knudsen, Jakob Grunnet, Bertholdt, L., Gudiksen, Anders, Gerbal-Chaloin, S. & Rasmussen, M. K., 2018, In: Toxicological Sciences. 162, 1, p. 309-317 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Skeletal muscle IL-6 and regulation of liver metabolism during high-fat diet and exercise training

    Knudsen, Jakob Grunnet, Joensen, E., Bertholdt, L., Jessen, H., van Hauen, L., Hidalgo, J. & Pilegaard, Henriette, 2016, In: Physiological Reports. 4, 9, 9 p., e12788.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials

    Pilmark, N. S., Oberholzer, L., Halling, Jens Frey, Kristensen, Jonas Møller, Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, Jesper Bratz, Larsen, E. L., Meinild-Lundby, A., Wojtaszewski, Jørgen F P, Pilegaard, Henriette, Poulsen, H., Pedersen, Bente Klarlund, Hansen, K. B. & Karstoft, Kristian, 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Skeletal muscle interleukin 6 in fasting and exercise-induced metabolic regulation in liver and adipose tissue

    Bertholdt, L., 2019, Department of Biology, Faculty of Science, University of Copenhagen. 179 p.

    Research output: Book/ReportPh.D. thesisResearch

  40. Published

    Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training

    Knudsen, Jakob Grunnet, Bertholdt, L., Joensen, E., Lassen, S. B., Hidalgo, J. & Pilegaard, Henriette, 2015, In: Obesity. 23, 8, p. 1616-1624 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Skeletal muscle to pancreatic β-cell cross-talk: the effect of humoral mediators liberated by muscle contraction and acute exercise on β-cell apoptosis

    Christensen, C. S., P. Christensen, D., Lundh, M., Dahllöf, M. S., Haase, T. N., Velasquez, J. M., Laye, M. J., Mandrup-Poulsen, Thomas & Solomon, T. P. J., Oct 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. E1289-E1298 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Sliding doors: heteromeric, volume-sensitive osmolyte channels

    Lambert, Ian Henry, 15 Nov 2017, In: The Journal of Physiology. 595, 22, p. 6807-6807 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Sodium, Glucose and Dysregulated Glucagon Secretion: The Potential of Sodium Glucose Transporters

    Armour, Sarah Louise, Früh, Alexander Erwin & Knudsen, Jakob Grunnet, 2022, In: Frontiers in Pharmacology. 13, 6 p., 837664.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers

    Xie, Y., Ruan, F., Li, Y., Luo, M., Zhang, C., Chen, Z., Xie, Z., Weng, Z., Chen, W., Chen, W., Fang, Y., Sun, Y., Guo, M., Wang, J., Xu, S., Wang, H. & Tang, C., 2024, In: eLife. 12, 20 p., RP87868.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Spatially resolved analysis of microenvironmental gradient impact on cancer cell phenotypes

    Auxillos, Jamie Yam, Crouigneau, R., Li, Y. F., Dai, Yifan, Stigliani, Arnaud, Tavernaro, I., Resch-Genger, U., Sandelin, Albin Gustav, Marie, R. & Pedersen, Stine Helene Falsig, 2024, In: Science Advances. 10, 18, 17 p., eadn3448.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Specific proliferative response of human lymphocytes to purified soluble antigens from Plasmodium falciparum in vitro cultures and to antigens from malaria patients' sera

    Bygbjerg, Ib Christian, Jepsen, S., Theander, Thor Grundtvig & Ødum, Niels, 1985, In: Clinical and Experimental Immunology. 59, 2, p. 421-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Spironolactone induces apoptosis and inhibits NF-kappaB independent of the mineralocorticoid receptor

    Sønder, S. U. S., Woetmann, Anders , Ødum, Niels & Bendtzen, K., 2006, In: Apoptosis. 11, 12, p. 2159-65 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

    Nielsen, M., Nissen, Mogens Holst, Gerwien, J., Zocca, M., Rasmussen, H. M., Nakajima, K., Röpke, C., Geisler, Carsten, Kaltoft, K. & Ødum, Niels, 2002, In: Blood. 99, 3, p. 973-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Spontaneous metastasis in congenic mice with transgenic breast cancer is unaffected by plasminogen gene ablation

    Almholt, K., Juncker-Jensen, A., Lærum, O. D., Johnsen, M., Rømer, J. & Lund, L. R., 2013, In: Clinical and Experimental Metastasis. 30, 3, p. 277-288 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review