Cell Biology and Physiology

  1. Published

    The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity

    Hendus-Altenburger, R., Vogensen, J., Pedersen, E. S., Luchini, A., Araya-Secchi, R., Bendsoe, A. H., Prasad, N. S., Prestel, Andreas, Cardenas, M., Pedraz-Cuesta, E., Arleth, Lise, Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 3 Dec 2020, In: Communications Biology . 3, 1, 18 p., 731.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The intraflagellar transport machinery in ciliary signaling

    Mourão, A., Christensen, Søren Tvorup & Lorentzen, E., 2016, In: Current Opinion in Structural Biology. 41, p. 98-108 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    The level of claudin-7 is reduced as an early event in colorectal carcinogenesis

    Lange, Jette Bornholdt, Friis, S., Godiksen, S., Poulsen, Steen Seier, Santoni Rugiu, Eric, Bisgaard, Hanne Cathrine, Lothe, I. M. B., Ikdahl, T., Tveit, K. M., Johnson, E., Kure, E. H. & Vogel, Lotte, 2011, In: B M C Cancer. 11, p. 65 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The lissencephaly protein Lis1 is present in motile mammalian cilia and requires outer arm dynein for targeting to Chlamydomonas flagella.

    Pedersen, Lotte Bang, Rompolas, P., Christensen, Søren Tvorup, Rosenbaum, J. L. & King, S. M., 2007, In: Journal of Cell Science. 120, Pt 5, p. 858-67 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The major basement membrane components localize to the chondrocyte pericellular matrix--a cartilage basement membrane equivalent?

    Kvist, A. J., Nyström, A., Hultenby, K., Sasaki, T., Talts, J. F. & Aspberg, A., 2007, In: Matrix Biology. 27, 1, p. 22-33 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer

    Berchtold, Martin Werner & Villalobo, A., 2014, In: B B A - Molecular Cell Research. 1843, 2, p. 398-435 38 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

    Benmerah, A., Durand, B., Giles, R. H., Harris, T., Kohl, L., Laclef, C., Meilhac, S. M., Mitchison, H. M., Pedersen, Lotte Bang, Roepman, R., Swoboda, P., Ueffing, M. & Bastin, P., 2015, In: Cilia. 4, 5, 14 p.

    Research output: Contribution to journalConference articleResearch

  9. Published

    The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

    Litman, Thomas, Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. & Bates, S. E., Jun 2000, In: Journal of Cell Science. 113 ( Pt 11), p. 2011-21 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

    Andersen, Anne Poder, Samsøe-Petersen, Jacob, Ørnbo, E. K., Bødtkjer, E., Moreira, José, Kveiborg, Marie & Pedersen, Stine Helene Falsig, 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis

    Kypri, E., Christodoulou, A., Maimaris, G., Lethan, M., Markaki, M., Lysandrou, C., Lederer, C., Tavernarakis, N., Geimer, S., Pedersen, Lotte Bang & Santama, N., 2014, In: Cellular and molecular life sciences : CMLS. 71, 3, p. 517-538 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The origin of myofibroblasts in breast cancer: Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells in conversion

    Rønnov-Jessen, Lone, Petersen, Ole William, Koteliansky, V. & Bissell, M. J., 1995, In: Journal of Clinical Investigation. 95, p. 859-873

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The p21 ras C-terminus is required for transformation and membrane association.

    Willumsen, Berthe Marie, Christensen, A., Hubbert, N. L., Papageorge, A. G. & Lowy, D. R., 1984, In: Nature. 310, 5978, p. 583-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion

    Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Bissell, M. J., 2001, In: Breast Cancer Research (Online Edition). 3, p. 213-217

    Research output: Contribution to journalReviewResearch

  15. Published

    The primary cilium at a glance

    Satir, P., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2010, In: Journal of Cell Science. 123, Pt 4, p. 499-503 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

    Clement, C. A., Kristensen, S. G., Møllgård, Kjeld, Pazour, G. J., Yoder, B. K., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, In: Journal of Cell Science. 122, Pt 17, p. 3070-82 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The primary cilium is a sensory organelle that regulates growth control and tissue homeostasis

    Christensen, Søren Tvorup, Schneider, L., Clement, C. A., Pazour, G., Hoffmann, E. K. & Satir, P., 2006, In: The FASEB Journal. 20, p. A437

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

    Rocchi, E., Khodjakov, A., Volk, E. L., Yang, C. H., Litman, Thomas, Bates, S. E. & Schneider, E., 29 Apr 2000, In: Biochemical and Biophysical Research Communications. 271, 1, p. 42-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

    Araya-Secchi, R., Bugge, K., Seiffert, P., Petry, A., Haxholm, G. W., Lindorff-Larsen, Kresten, Pedersen, Stine Helene Falsig, Arleth, Lise & Kragelund, Birthe Brandt, 2023, In: eLife. 12, 27 p., e84645.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The pump and leak steady-state concept with a variety of regulated leak pathways.

    Hoffmann, E. K., 2001, In: Journal of Membrane Biology. 184, 3, p. 321-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The rapid “teabag” method for high-end purification of membrane proteins

    Hering, J., Missel, Julie Winkel, Zhang, L., Gunnarsson, A., Castaldo, M., Pedersen, Per Amstrup, Ek, M., Gourdon, Pontus Emanuel & Snijder, H. J., 2020, In: Scientific Reports. 10, 11 p., 16167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The relation between T-cell expression of LFA-1 and immunological memory

    Hviid, Lars, Ødum, Niels & Theander, Thor Grundtvig, 1993, In: Immunology. 78, 2, p. 237-43 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The retinoblastoma protein: multitasking to suppress tumorigenesis

    Vormer, T. L., Hansen, Jacob B. & Riele, H. T., 2015, In: Molecular & Cellular Oncology. 2, 1, 2 p., e968062-1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The role of Glu327 of the a-subunit in coordinating Na + and K+ in binding and occlusion in Na,K-ATPase

    Rasmussen, J. H., Pedersen, Per Amstrup, Xielsen, J. M., Lanfermeijer, F. C. & Jorgcnsen, P. L., 1 Dec 1997, In: FASEB Journal. 11, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The role of TMEM16A (ANO1) and TMEM16F (ANO6) in cell migration

    Jacobsen, K. S., Zeeberg, K., Sauter, D. R. P., Poulsen, K. A., Hoffmann, E. K. & Schwab, A., 2013, In: Pflügers Archiv - European Journal of Physiology. 465, 12, p. 1753-1762 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The role of half-transporters in multidrug resistance

    Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, Dec 2001, In: Journal of Bioenergetics and Biomembranes. 33, 6, p. 503-11 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The role of volume-sensitive ion transport systems in regulation of epithelial transport

    Hoffmann, E. K., Schettino, T. & Marshall, W. S., 2007, In: Comparative Biochemistry and Physiology A. 148, 1, p. 29-43 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The role of water coordination in the pH-dependent gating of hAQP10

    Truelsen, S. F., Missel, Julie Winkel, Gotfryd, K., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel, Lindorff-Larsen, Kresten & Hélix-Nielsen, C., 2022, In: B B A - Biomembranes. 1864, 1, 13 p., 183809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The use of paracetamol during pregnancy: A qualitative study and possible strategies for a clinical trial

    Vedel, C., Jørgensen, D. S., Kristensen, D. M., Petersen, Olav Bennike Bjørn & Greisen, Gorm, 2022, In: PLoS ONE. 17, e0271537.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The volume activated potassium channel KCNK5 is up-regulated in activated human T Cells, but volume regulation is impaired

    Kirkegaard, S. S., Strøm, P. D., Gammeltoft, S., Hansen, A. J. & Hoffmann, E. K., 2016, In: Cellular Physiology and Biochemistry. 38, 3, p. 883-892 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4

    Thiesen, L., Belew, Zeinu Mussa, Griem-Krey, Nane, Pedersen, Stine Helene Falsig, Crocoll, C., Nour-Eldin, Hussam Hassan & Wellendorph, Petrine, 15 Feb 2020, In: European Journal of Pharmaceutical Sciences. 143, p. 1-9 105203.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Thermotolerance experiments on active and desiccated states of Ramazzottius varieornatus emphasize that tardigrades are sensitive to high temperatures

    Neves, R. C., Hvidepil, L. K. B., Sørensen-Hygum, T. L., Stuart, R. M. & Møbjerg, Nadja, 2020, In: Scientific Reports. 10, 12 p., 94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

    Sun, C., Wang, H., Ma, Q., Chen, C., Yue, J., Li, B. & Zhang, X., 2021, In: Cell and Bioscience. 11, 12 p., 24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Time-dependent regulation of hepatic cytochrome P450 mRNA in male liver-specific PGC-1α knockout mice

    Sundekilde, U. K., Kristensen, C. M., Olsen, M. A., Pilegaard, Henriette & Rasmussen, M. K., 2022, In: Toxicology. 469, 8 p., 153121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Trafficking, localization and degradation of the Na+,HCO3- Co-transporter NBCn1 in kidney and breast epithelial cells

    Olesen, C. W., Vogensen, J., Axholm, I., Severin, M., Schnipper, J., Pedersen, I. S., von Stemann, J. H., Schrøder, J. M., Christensen, D. P. & Pedersen, Stine Helene Falsig, 2018, In: Scientific Reports. 8, p. 1-16 7435.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Training state and fasting-induced PDH regulation in human skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Villesen, I., Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1633-1645 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors

    Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, K., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2004, In: Clinical Cancer Research. 10, 24, p. 8521-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Transcriptomic Profile of the Mouse Postnatal Liver Development by Single-Nucleus RNA Sequencing

    Xu, J., Hao, S., Shi, Q., Deng, Q., Jiang, Y., Guo, P., Yuan, Y., Shi, X., Shangguan, S., Zheng, H., Lai, G., Huang, Y., Wang, Y., Song, Y., Liu, Y., Wu, L., Wang, Z., Cheng, J., Wei, X., Cheng, M. & 6 others, Lai, Y., Volpe, G., Esteban, M. A., Hou, Y., Liu, C. & Liu, L., 2022, In: Frontiers in Cell and Developmental Biology. 10, 11 p., 833392.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains.

    Willumsen, Berthe Marie, Papageorge, A. G., Hubbert, N., Bekesi, E., Kung, H. F. & Lowy, D. R., 1985, In: EMBO Journal. 4, 11, p. 2893-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Transient accumulation and bidirectional movement of KIF13B in primary cilia

    Juhl, A. D., Anvarian, Zeinab, Kuhns, S., Berges, J., Andersen, J. S., Wüstner, D. & Pedersen, Lotte Bang, 2023, In: Journal of Cell Science. 136, 5, 8 p., jcs259257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Transient receptor potential channels in mechanosensing and cell volume regulation.

    Pedersen, Stine Helene Falsig & Nilius, B., 2007, In: Methods in Enzymology. 428, p. 183-207 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Translational frontiers: insight from lymphatics in skin regeneration

    Jiang, Y. & Perez-Moreno, Mirna, 2024, In: Frontiers in Physiology. 15, 8 p., 1347558.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster

    Novotny, G. W., Sonne, Si Brask, Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Kjems, J. & Leffers, H., 2007, In: Cell Death and Differentiation. 14, 4, p. 879-82 3 p.

    Research output: Contribution to journalLetterResearch

  45. Published

    Transmembrane transporter proteins: Capturing transport in motion

    Loland, Claus Juul, Wellendorph, Petrine, Pedersen, Stine Helene Falsig & Gether, Ulrik, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 2, p. 203-205 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  46. Published

    Tubulin transport in cilia: how many tubulin cargo-binding sites per IFT particle? (retrospective on DOI 10.1002/bies.201400007)

    Pedersen, Lotte Bang, 2017, In: BioEssays. 39, 1, 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  47. Published

    Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment

    Fontenete, S., Lerche, Catharina Margrethe, Paasch, U., Perez-Moreno, Mirna, Olesen, U. H. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity

    Kim, Jiyoung, Villadsen, René, Sørlie, T., Fogh, L., Grønlund, S. Z., Fridriksdóttir, A. J. R., Kuhn, I., Rank, F., Wielenga, V. T., Solvang, H., Edwards, P. A. W., Børresen-Dale, A., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6124-6129 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer

    Pedersen, A., Mendes Lopes de Melo, J., Mørup, N., Tritsaris, Katerina & Pedersen, Stine Helene Falsig, 2017, In: BMC Cancer. 17, 15 p., 542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Tun formation is not a prerequisite for desiccation tolerance in the marine tidal tardigrade Echiniscoides sigismundi

    Hygum, T. L., Clausen, L. K. B., Halberg, Kenneth Veland, Jørgensen, Aslak & Møbjerg, Nadja, 2016, In: Linnean Society. Zoological Journal. 178, 4, p. 907-911 5 p.

    Research output: Contribution to journalConference articleResearchpeer-review