Cell Biology and Physiology

  1. 2016
  2. Published

    A bovine in vitro blood-brain barrier model under oxygenglucose deprivation (OGD) condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016.

    Research output: Contribution to conferencePosterResearch

  3. Published

    Modeling the ischemic blood-brain barrier; the effects of oxygen-glucose deprivation (OGD) on endothelial cells in culture

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, Helle S. & Larsen, Birger Brodin, 19 Jun 2016.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  4. Published

    Cellular uptake of metallated cobalamins

    Tran, M. T. Q., Stürup, Stefan, Lambert, Ian Henry, Gammelgaard, Bente, Furger, E. & Alberto, R., 2016, In: Metallomics. 8, 3, p. 298-304 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Inflammatory Cytokines Stimulate Bone Morphogenetic Protein-2 Expression and Release from Pancreatic Beta Cells

    Urizar, A. I., Friberg, J., Christensen, D. P., Christensen, G. L. & Billestrup, Nils, 1 Jan 2016, In: Journal of Interferon & Cytokine Research. 36, 1, p. 20-29

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Targeting of ASH domain-containing proteins to the centrosome

    Verdier, P., Morthorst, Stine Kjær & Pedersen, Lotte Bang, 2016, Cilia. Satir, P. & Tvorup Christensen, S. (eds.). Springer, p. 15-33 19 p. (Methods in Molecular Biology, Vol. 1454).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  7. Published

    Immunofluorescence Microscopy and mRNA Analysis of Human Embryonic Stem Cells (hESCs) Including Primary Cilia Associated Signaling Pathways

    Vestergaard, M. L., Awan, A., Warzecha, C. B., Christensen, Søren Tvorup & tcg964, tcg964, 2016, Human Embryonic Stem Cell Protocols. Springer Science+Business Media, Vol. 1307. p. 123-140 (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  8. Published

    In silico analysis of the transportome in human pancreatic ductal adenocarcinoma

    Zaccagnino, A., Pilarsky, C., Tawfik, D., Sebens, S., Trauzold, A., Novak, Ivana, Schwab, A. & Kalthoff, H., 2016, In: European Biophysics Journal. 45, 7, p. 749-763 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Assessment of different 3D culture systems to study tumor phenotype and chemosensitivity in pancreatic ductal adenocarcinoma

    Zeeberg, K., Cardone, R. A., Greco, M. R., Saccomano, M., Nøhr-Nielsen, A., Alves, F., Pedersen, Stine Helene Falsig & Reshkin, S. J., 2016, In: International Journal of Oncology. 49, 1, p. 243-252 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2015
  11. Published

    Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling

    Basse, A. L., Dixen, K., Yadav, R., Tygesen, M. P., Qvortrup, Klaus, Kristiansen, Karsten, Quistorff, B., Gupta, R., Wang, J. & Hansen, Jacob B., 2015, In: BMC Genomics. 16, 19 p., 215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

    Benmerah, A., Durand, B., Giles, R. H., Harris, T., Kohl, L., Laclef, C., Meilhac, S. M., Mitchison, H. M., Pedersen, Lotte Bang, Roepman, R., Swoboda, P., Ueffing, M. & Bastin, P., 2015, In: Cilia. 4, 5, 14 p.

    Research output: Contribution to journalConference articleResearch

  13. Published

    Skeletal muscle to pancreatic β-cell cross-talk: the effect of humoral mediators liberated by muscle contraction and acute exercise on β-cell apoptosis

    Christensen, C. S., P. Christensen, D., Lundh, M., Dahllöf, M. S., Haase, T. N., Velasquez, J. M., Laye, M. J., Mandrup-Poulsen, Thomas & Solomon, T. P. J., Oct 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. E1289-E1298 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis

    Dam, C. S., Henarejos, S. A. P., Tsolakou, T., Segato, C. A., Gammelgaard, Bente, Yellol, G. S., Ruiz, J., Lambert, Ian Henry & Stürup, Stefan, 2015, In: Metallomics. 5, p. 885-895 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle

    Edge, J., Muendel, T., Pilegaard, Henriette, Hawke, E., Leikis, M., Lopez-Villalobos, N., Oliveira, R. S. F. & Bishop, D. J., 2015, In: P L o S One. 10, 12, 14 p., e0141317.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells

    Giannuzzo, A., Pedersen, Stine Helene Falsig & Novak, Ivana, 2015, In: Molecular Cancer. 14, 15 p., 203.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mechanisms Regulating Acid-Base Transporter Expression in Breast- and Pancreatic Cancer: Contributions to the Cancer Phenotype

    Gorbatenko, A., 2015, Department of Biology, Faculty of Science, University of Copenhagen. 180 p.

    Research output: Book/ReportPh.D. thesisResearch

  19. Published

    Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

    Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance

    Hoffmann, E. K., Sørensen, B. H., Sauter, D. R. P. & Lambert, Ian Henry, 2015, In: Channels (Austin). 9, 6, p. 380-396 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training

    Knudsen, Jakob Grunnet, Bertholdt, L., Joensen, E., Lassen, S. B., Hidalgo, J. & Pilegaard, Henriette, 2015, In: Obesity. 23, 8, p. 1616-1624 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Vasopressin regulation of sodium transport in the distal nephron and collecting duct

    Kortenoeven, M. L. A., Pedersen, N. B., Rosenbæk, L. L. & Fenton, R. A., 2015, In: American Journal of Physiology: Renal Physiology. 309, 4, p. F280-F299 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Physiological role of taurine - from organism to organelle

    Lambert, Ian Henry, Kristensen, D. M. B., Holm, J. B. & Mortensen, Ole Hartvig, 2015, In: Acta Physiologica (Print). 213, 1, p. 191-212 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Regulation of p53 in NIH3T3 mouse fibroblasts following hyperosmotic stress

    Lambert, Ian Henry, Enghoff, M. S., Brandi, M. & Hoffmann, E. K., 2015, In: Physiological Reports. 3, 6, 9 p., e12412.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Antifungal properties of peptidomimetics with an arginine-[β-(2,5,7-tri-tert-butylindol-3-yl)alanine]-arginine motif against Saccharomyces cerevisiae and Zygosaccharomyces bailii

    Larsen, C. E., Larsen, C. J., Franzyk, Henrik & Regenberg, Birgitte, 2015, In: F E M S Yeast Research. 15, 3, 8 p., fov011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Coordination of TGFβ/BMP signaling is associated with the primary cilium

    Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  27. Published

    A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

    Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

    Nadeem, A., Sanborn, J., Gettel, D. L., Ho C.S., J., Rydström, A., Ngassam, V. N., Klausen, T. K., Pedersen, Stine Helene Falsig, Lam, M., Parikh, A. N. & Svanborg, C., 2015, In: Scientific Reports. 5, 14 p., 16432.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Expression of the oncogenic, constitutive active Platelet-Derived Growth Factor Receptor alpha D842V mutant induces loss of primary cilia

    Nielsen, B. S., Schmid, F., Malinda, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., P63.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells

    Nygaard, M. B., Almstrup, Kristian, Lindbæk, L., Christensen, Søren Tvorup & Svingen, T., 2015, In: Scientific Reports. 5, 14 p., 10364 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The identification of a volume-regulated anion channel: an amazing Odyssey

    Pedersen, Stine Helene Falsig, Klausen, T. K. & Nilius, B., 2015, In: Acta Physiologica (Print). 213, 4, p. 868-881 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells

    Rasmussen, L. J. H., Mûller, H. S. H., Jørgensen, B., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2015, In: American Journal of Physiology: Cell Physiology. 308, 2, p. C101-C110 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis

    Sales, K. U., Friis, S., Konkel, J. E., Godiksen, S., Hatakeyama, M., Hansen, K. K., Rogatto, S. R., Szabo, R., Vogel, Lotte, Chen, W., Gutkind, J. S. & Bugge, T. H., 15 Jan 2015, In: Oncogene. 34, 3, p. 346-356 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Evolutionary implications of localization of the signaling scaffold protein Parafusin to both cilia and the nucleus

    Satir, B. H., Wyroba, E., Liu, L., Lethan, M., Satir, P. & Christensen, Søren Tvorup, 2015, In: Cell Biology International. 39, 2, p. 136-145 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)

    Sauter, D. R. P., Novak, Ivana, Pedersen, Stine Helene Falsig, Larsen, Erik Hviid & Hoffmann, E. K., 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1495-1508 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Kinesin-3 motor protein KIF13B localizes to centrosomes and primary cilia and regulates ciliary length and signaling

    Schou, K. B., Mogensen, J. B., Aleliunaite, A., Morthorst, Stine Kjær, Veland, I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., O3.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  38. Published

    Ins and outs of GPCR signaling in primary cilia

    Schou, K. B., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2015, In: E M B O Reports. 16, 9, p. 1099-1113 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor

    Schultz, H. S., Nitze, L. M., Zeuthen, L. H., Keller, P., Gruhler, A., Pass, J., Chen, J., Guo, L., Fleetwood, A. J., Hamilton, J. A., Berchtold, Martin Werner & Panina, S., 2015, In: Journal of Immunology. 194, 7, p. 3169-3179 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

    Sigurðsson, H. H., Olesen, C. W., Dybboe, R., Lauritzen, G. & Pedersen, Stine Helene Falsig, 2015, In: Molecular Cancer Research. 13, 1, p. 63-77 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    CSPP-L and EB3 localize to centriolar satellites and are required for satellite-dependent recruitment of ciliopathy proteins to the centrosome

    Sternemalm, J., Geimer, S., Aarnes, E. K., Frikstad, K. M., Stokke, T., Pedersen, Lotte Bang & Patzke, S., 2015, In: Cilia. 4, Suppl. 1, 1 p., P76.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    Integrin β1, osmosensing, and chemoresistance in mouse ehrlich carcinoma cells

    Sørensen, B. H., Rasmussen, L. J. H., Broberg, B. S., Klausen, T. K., Sauter, D. R. P., Lambert, Ian Henry, Aspberg, A. & Hoffmann, E. K., 2015, In: Cellular Physiology and Biochemistry. 36, 1, p. 111-132 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Changes in barrier properties and protein expression levels of bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 27 Aug 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  44. Published

    Changes in protein expression levels, Claudin-5 localization and barrier function in bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 4 Jul 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  45. Published

    The in vitro blood-brain barrier model under OGD condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  46. Published

    The retinoblastoma protein: multitasking to suppress tumorigenesis

    Vormer, T. L., Hansen, Jacob B. & Riele, H. T., 2015, In: Molecular & Cellular Oncology. 2, 1, 2 p., e968062-1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2014
  48. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer

    Berchtold, Martin Werner & Villalobo, A., 2014, In: B B A - Molecular Cell Research. 1843, 2, p. 398-435 38 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Phosphorylation of rat melanopsin at Ser-381 and Ser-398 by light/dark and its importance for intrinsically photosensitive ganglion cells (ipRGCs) cellular Ca2+ signaling

    Fahrenkrug, J., Falktoft, B., Georg, B., Hannibal, Jens, Kristiansen, S. B. & Klausen, T. K., 2014, In: Journal of Biological Chemistry. 289, 51, p. 35482-35493 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J Mice

    Fjære, E., Aune, U. L., Røen, K., Keenan, A. H., Ma, Tao, Borkowski, K., Kristensen, D. M. B., Novotny, G. W., Mandrup-Poulsen, Thomas, Hudson, B. D., Milligan, G., Xi, Y., Newman, J. W., Haj, F. G., Liaset, B., Kristiansen, Karsten & Madsen, L., 2014, In: The Journal of Biological Chemistry. 289, 23, p. 16032-16045 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Urokinase plasminogen activator is a central regulator of macrophage three-dimensional invasion, matrix degradation, and adhesion

    Fleetwood, A. J., Achuthan, A., Schultz, H. S., Nansen, A., Almholt, K., Usher, P. & Hamilton, J. A., 2014, In: Journal of Immunology. 192, 8, p. 3540-3547 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides

    Fredholm, S., Gjerdrum, Lise Mette Rahbek, Willerslev-Olsen, A., Petersen, D. L., Nielsen, I. Ø., Kauczok, C., Wobser, M., Ralfkiaer, U., Bonefeld, Charlotte Menne, Wasik, M. A., Krejsgaard, T., Geisler, Carsten, Ralfkiaer, E., Gniadecki, R., Woetmann, Anders & Ødum, Niels, 2014, In: Anticancer Research. 34, 10, p. 5277-5286 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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