Cell Biology and Physiology

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  1. Published

    Effects of acid-adaptation on cancer cell acid-base regulation, metabolism and stemness

    Rolver, M. G., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 190 p.

    Research output: Book/Report › Ph.D. thesis › Research

  2. Published

    Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1

    Rolver, M. G., Elingaard-Larsen, L. O., Andersen, Anne Poder, Counillon, L. & Pedersen, Stine Helene Falsig, 2020, In: Scientific Reports. 10, 17 p., 5800.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Assessing Cell Viability and Death in 3D Spheroid Cultures of Cancer Cells

    Rolver, M. G., Elingaard-Larsen, L. O. & Pedersen, Stine Helene Falsig, 2019, In: Journal of Visualized Experiments. 2019, 148, e59714.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Chronic acidosis rewires cancer cell metabolism through PPARα signaling

    Rolver, M. G., Holland, L. K. K., Ponniah, M., Prasad, N. S., Yao, Jiayi, Schnipper, J., Kramer, S., Elingaard-Larsen, L., Pedraz-Cuesta, E., Liu, B., Pardo, L. A., Maeda, K., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 8, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Differential effects of EGFR ligands on endocytic sorting of the receptor

    Roepstorff, K., Grandal, M. V., Henriksen, L., Knudsen, S. L. J., Lerdrup, Mads, Grøvdal, L., Willumsen, Berthe Marie & van Deurs, B., 2009, In: Traffic - International Journal of Intracellular Transport. 10, 8, p. 1115-27 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Human AQP5 facilitates hydrogen peroxide permeation and improves cell resistance to oxidative stress

    Rodrigues, C., Mósca, A. F., Lopes, D., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2018, In: Free Radical Biology and Medicine. 120, Suppl. 1, p. S70 P-86.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  7. Published

    Human aquaporin-5 facilitates hydrogen peroxide permeation affecting adaption to oxidative stress and cancer cell migration

    Rodrigues, C., Pimpão, C., Mósca, A. F., Coxixo, A. S., Lopes, D., Da Silva, I. V., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2019, In: Cancers. 11, 7, 17 p., 932.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: sequence comparison reveals a putative recombinational enhancer element

    Roch, F. A., Hobi, R., Berchtold, Martin Werner & Kuenzle, C. C., 1997, In: Nucleic Acids Research. 25, 12, p. 2303-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

    Rocchi, E., Khodjakov, A., Volk, E. L., Yang, C. H., Litman, Thomas, Bates, S. E. & Schneider, E., 29 Apr 2000, In: Biochemical and Biophysical Research Communications. 271, 1, p. 42-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)

    Robey, R. W., Honjo, Y., van de Laar, A., Miyake, K., Regis, J. T., Litman, Thomas & Bates, S. E., 6 Jun 2001, In: BBA General Subjects. 1512, 2, p. 171-82 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

    Robey, R. W., Medina-Pérez, W. Y., Nishiyama, K., Lahusen, T., Miyake, K., Litman, Thomas, Senderowicz, A. M., Ross, D. D. & Bates, S. E., Jan 2001, In: Clinical Cancer Research. 7, 1, p. 145-52 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833

    Robey, R., Bakke, S., Stein, W., Meadows, B., Litman, Thomas, Patil, S., Smith, T., Fojo, T. & Bates, S., 1 Jan 1999, In: Blood. 93, 1, p. 306-14 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

    Jørgensen, Stine Ringholm, Gudiksen, Anders, Halling, Jens Frey, Qoqaj, A., Rasmussen, P. M., Prats Gavalda, Clara, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 3, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Development and validation of an ICP-MS method for quantification of total carbon and platinum in cell samples and comparison of open-vessel and microwave-assisted acid digestion methods

    Riisom, M., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 158, p. 144-150 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Beta-1 and Not Beta-3 Adrenergic Receptors May Be the Primary Regulator of Human Brown Adipocyte Metabolism

    Riis-Vestergaard, M. J., Richelsen, B., Bruun, J. M., Li, W., Hansen, Jacob B. & Pedersen, S. B., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, 12 p., dgz298.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Regulation of polycystin-2 trafficking to and at the primary cilium in kidney epithelial cells

    Rezi, Csenge Kata, 2024, Department of Biology, Faculty of Science, University of Copenhagen. 188 p.

    Research output: Book/Report › Ph.D. thesis › Research

  17. Published

    Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts.

    Rentsch, M. L., Ossum, C. G., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: Pflügers Archiv: European Journal of Physiology. 454, 4, p. 649-62 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effects of chemical anoxia on NHE1, p38 MAPK, p53, Akt and ERM proteins in NIH3T3 fibroblasts: evidence for a role of NHE1 upstream of p38 MAPK

    Rentsch, M. L., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: The FASEB Journal. 5, p. A1158

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Sprifermin (rhFGF18) versus vehicle induces a biphasic process of extracellular matrix remodeling in human knee OA articular cartilage ex vivo

    Reker, D., Siebuhr, A. S., Thudium, C. S., Gantzel, T., Ladel, C., Michaelis, M., Aspberg, A., Berchtold, Martin Werner, Karsdal, M. A., Gigout, A. & Bay-Jensen, A. C., 2020, In: Scientific Reports. 10, 9 p., 6011.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism

    Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Clonal yeast biofilms can reap competitive advantages through cell differentiation without being obligatorily multicellular

    Regenberg, Birgitte, Hanghøj, Kristian Ebbesen, Andersen, K. S. & Boomsma, Jacobus J., 2016, In: Royal Society of London. Proceedings B. Biological Sciences. 283, 1842, 8 p., 20161303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. E-pub ahead of print

    The impact of the migraine treatment onabotulinumtoxinA on inflammatory and pain responses: Insights from an animal model

    Reducha, Philip Victor, Bömers, J. P., Edvinsson, L. & Haanes, Kristian Agmund, 2024, (E-pub ahead of print) In: Headache.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Could Experimental Inflammation Provide Better Understanding of Migraines?

    Reducha, Philip Victor, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: Cells. 11, 15, 17 p., 2444.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Rodent behavior following a dural inflammation model with anti-CGRP migraine medication treatment

    Reducha, Philip Victor, Bömers, J. P., Edvinsson, L. & Haanes, Kristian Agmund, 2023, In: Frontiers in Neurology. 14, 13 p., 1082176.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Xenobiotic Exposure and Migraine-Associated Signaling: A Multimethod Experimental Study Exploring Cellular Assays in Combination with Ex Vivo and In Vivo Mouse Models

    Rasmussen, Rikke Holm, Christensen, S. L., Callø, Kirstine, Nielsen, B. S., Rehfeld, A., Taylor-Clark, T. E., Haanes, Kristian Agmund, Taboureau, O., Audouze, K., Klærke, Dan Arne, Olesen, Jes & Kristensen, D. M., 2023, In: Environmental Health Perspectives. 131, 11, 14 p., 117003.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Ex vivo Release of Calcitonin Gene-Related Peptide from the Trigeminovascular System in Rodents

    Rasmussen, R. H., Jansen-Olesen, I., Kristensen, D. M. & Christensen, S. L., 2022, In: Journal of Visualized Experiments. 183, 19 p., e63723.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Hepatic PGC-1α has minor regulatory effect on the liver transcriptome and metabolome during high fat high fructose diet and exercise training

    Rasmussen, M. K., Thøgersen, R., Horsbøl Lindholm, P., Bertram, H. C. & Pilegaard, Henriette, 2023, In: Gene. 851, 14 p., 147039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice

    Rasmussen, M. K., Bertholdt, L., Gudiksen, Anders, Pilegaard, Henriette & Knudsen, Jakob Grunnet, 2018, In: Toxicology Letters. 282, p. 93-99 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications

    Rasmussen, M., Alexander, R. T., Darborg, B. V., Møbjerg, Nadja, Hoffmann, E. K., Kapus , A. & Pedersen, Stine Helene Falsig, 2008, In: American Journal of Physiology: Cell Physiology. 294, 1, p. C197-C212 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells

    Rasmussen, L. J. H., Mûller, H. S. H., Jørgensen, B., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2015, In: American Journal of Physiology: Cell Physiology. 308, 2, p. C101-C110 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Mechanisms of gemcitabine-resistance in pancreatic cancer cells

    Rasmussen, L. J. H., Ossum, C. G., Tvingsholm, S., Lambert, Ian Henry & Hoffmann, E. K., 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1321-1322 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  32. Published

    Prolactin and oestrogen synergistically regulate gene expression and proliferation of breast cancer cells

    Rasmussen, L. M., Frederiksen, K. S., Din, N., Galsgaard, E., Christensen, L., Berchtold, Martin Werner & Panina, S., 16 Aug 2010, In: Endocrine - Related Cancer. 17, 3, p. 809-822

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

    Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    High yield fermentation of pig α1β1 Na,K-ATPase in Saccharomyces cerevisiae

    Rasmussen, J. H., Pedersen, Per Amstrup & Jorgensen, P. L., 1 Jan 1997, In: Annals of the New York Academy of Sciences. 834, p. 469-471 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The role of Glu327 of the a-subunit in coordinating Na + and K+ in binding and occlusion in Na,K-ATPase

    Rasmussen, J. H., Pedersen, Per Amstrup, Xielsen, J. M., Lanfermeijer, F. C. & Jorgcnsen, P. L., 1 Dec 1997, In: FASEB Journal. 11, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen

    Rasmussen, A. B., Zocca, M., Bonefeld, Charlotte Menne, von Essen, Marina Rode, Lauritsen, J. P., Tomra, S., Ødum, Niels & Geisler, Carsten, 2004, In: Scandinavian Journal of Immunology. 59, 2, p. 220-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

    Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Litman, Thomas, Woetmann, Anders , Glue, C., Røpke, M. A., Skov, Lone & Ødum, Niels, 2011, In: Blood. 118, 22, p. 5891-5900 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Environmental DNA metabarcoding of Danish soil samples reveals new insight into the hidden diversity of eutardigrades in Denmark

    Pust, F. L., Frøslev, Tobias Guldberg, Kristensen, Reinhardt Møbjerg & Møbjerg, Nadja, 2024, In: Zoological Journal of the Linnean Society. 200, 1, p. 20-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Recombinant production of membrane proteins in yeast

    Preisler, Sarah Spruce, Hansen, K. M., Nurup, C. N., Beich-Frandsen, M. & Pedersen, Per Amstrup, 2021, Methods in Enzymology. Pyle, A. M. & Christianson, D. W. (eds.). Academic Press, Vol. 660. p. 21-52 32 p. (Methods in Enzymology, Vol. 660).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  40. Published

    Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins

    Preisler, Sarah Spruce, Wiuf, A. D., Friis, M., Kjaergaard, L., Hurd, M., Becares, E. R., Nurup, C. N., Bjoerkskov, F. B., Szathmáry, Z., Gourdon, Pontus Emanuel, Callø, Kirstine, Klærke, Dan Arne, Gotfryd, K. & Pedersen, Per Amstrup, 2021, In: Current research in structural biology. 3, p. 51-71 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae

    Prada Luengo, Inigo, Møller, H. D., Henriksen, Rasmus Henrik Amund, Gao, Q., Larsen, C. E., Alizadeh, S., Maretty, L., Houseley, J. & Regenberg, Birgitte, 2020, In: Nucleic Acids Research. 48, 14, p. 7883-7898 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Plasma volume in acute hypoxia: comparison of a carbon monoxide rebreathing method and dye dilution with Evans' blue

    Poulsen, T. D., Klausen, T., Richalet, J. P., Kanstrup, I. L., Fogh-Andersen, N. & Olsen, N. V., Apr 1998, In: European Journal of Applied Physiology and Occupational Physiology. 77, 5, p. 457-61 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Deregulation of apoptotic volume decrease and ionic movements in multidrug-resistant tumor cells: role of chloride channels

    Poulsen, K. A., Andersen, E. C., Hansen, C. F., Klausen, T. K., Hougaard, C., Lambert, Ian Henry & Hoffmann, E. K., 2010, In: American Journal of Physiology: Cell Physiology. 298, 1, p. C14-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    NEW ASPECTS OF AVD AND PUTATIVE ROLES OF NOVEL CHLORIDE CHANNELS

    Poulsen, K. A., Grubb, S., Klausen, T. K., Larsen, Erik Hviid & Hoffmann, E. K., 2009, In: Journal of Physiological Sciences. Suppl. 1, p. 392-392

    Research output: Contribution to journal › Conference abstract in journal › Research

  45. Published

    Reply to "Letter to the editor: ‘AVD1, AVDT, AVD2 in cisplatin-induced apoptosis: differences between WT EATC and MDR EATC resting on differing expression levels of type-1 porin/VDAC in cell membranes?'"

    Poulsen, K. A. & Hoffmann, E. K., 2010, In: American Journal of Physiology: Cell Physiology. 298, 5, p. C1277 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  46. Published

    Role of phospholipase A2 in the induction of drip loss in porcine muscle.

    Poulsen, K. A., Young, J. F., Theil, P., Kolko, Miriam, Oksbjerg, N. & Lambert, Ian Henry, 2007, In: Journal of Agricultural and Food Chemistry. 55, 5, p. 1970-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells

    Poulsen, K. A., Litman, Thomas, Eriksen, J., Mollerup, J. & Lambert, Ian Henry, Jun 2002, In: Amino Acids. 22, 4, p. 333-50 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Induction of group VIA phospholipase A2 activity during in vitro ischemia in C2C12 myotubes is associated with changes in the level of its splice variants.

    Poulsen, K. A., Pedersen, Stine Helene Falsig, Kolko, M. & Lambert, Ian Henry, 2007, In: American Journal of Physiology: Cell Physiology. 293, 5, p. C1605-15

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma

    Porter, S., Span, P. N., Sweep, F. C. G. J., Tjan-Heijnen, V. C. G., Pennington, C. J., Pedersen, T. X., Johnsen, M., Lund, L. R., Rømer, J. & Edwards, D. R., 2006, In: International Journal of Cancer. 118, 5, p. 1241-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans

    Plomgaard, Peter Stendahl, Hansen, J. S., Townsend, L. K., Gudiksen, Anders, Secher, Niels H., Clemmesen, J. O., Støving, R. K., Goetze, Jens P. , Wright, D. C. & Pilegaard, Henriette, 2022, In: Frontiers in Endocrinology. 13, 1037948.

    Research output: Contribution to journal › Journal article › Research › peer-review

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