- 2022
- Published
Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system: expression, release and interactions with 5-HT1 receptors
Edvinsson, J. C. A., Maddahi, A., Christiansen, I. M., Reducha, Philip Victor, Warfvinge, K., Sheykhzade, Majid, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: The Journal of Headache and Pain. 23, 19 p., 26.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipolysis regulates major transcriptional programs in brown adipocytes
Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of tetraspanin-7 expression reduces pancreatic β-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism
McLaughlin, K., Acreman, S., Nawaz, S., Cutteridge, J., Clark, A., Knudsen, Jakob Grunnet, Denwood, G., Spigelman, A. F., Fox, J. E. M., Singh, S. P., MacDonald, P. E., Hastoy, B. & Zhang, Q., 2022, In: Diabetic Medicine. 39, 12, 13 p., e14984.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Massively targeted evaluation of therapeutic CRISPR off-targets in cells
Pan, X., Qu, K., Yuan, H., Xiang, X., Anthon, C., Pashkova, L., Liang, X., Han, P., Corsi, G. I., Xu, F., Liu, P., Zhong, J., Zhou, Y., Ma, T., Jiang, H., Liu, J., Wang, J., Jessen, N., Bolund, L., Yang, H. & 5 others, , 2022, In: Nature Communications. 13, 14 p., 4049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation
Goldhammer, N., Kim, Jiyoung, Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2022, In: Communications Biology . 5, 1, 13 p., 219.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Sequencing Approaches for the High-Throughput Identification of Full-length Poly(A) RNA Transcripts at the Single-cell Level
XIE, Z., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 88 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats
Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Paracetamol Use During Pregnancy - A Call for Precautionary Action
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2022, In: Obstetrical and Gynecological Survey. 77, 3, p. 133-134 2 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Peter Satir (1936-2022), cell biology pioneer and mentor
Sale, W. S. & Christensen, Søren Tvorup, 2022, In: Journal of Cell Science. 135, 23Research output: Contribution to journal › Comment/debate › Research
- Published
Phase I study of adjuvant immunotherapy with autologous tumor-infiltrating lymphocytes in locally advanced cervical cancer
Huang, H., Nie, C-P., Liu, X., Song, B., Yue, J., Xu, J., He, J., Li, K., Feng, Y., Wan, T., Zheng, M., Zhang, Y-N., Ye, W-J., Li, J-D., Li, Y-F., Li, J., Cao, X-P., Liu, Z., Zhang, X., Liu, Q. & 3 others, , 2022, In: Journal of Clinical Investigation. 132, 15, 15 p., e157726.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5
Merklinger, L., Bauer, J., Pedersen, Per Amstrup, Damgaard, R. B. & Morth, J. P., 2022, In: Life Science Alliance. 5, 8, 13 p., e202101309.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of an Active, Human Membrane Protein in Saccharomyces cerevisiae: Full-Length FICD
Virolainen, M. S., Søltoft, C. L., Pedersen, Per Amstrup & Ellgaard, Lars, 2022, In: International Journal of Molecular Sciences. 23, 5, 17 p., 2458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to ‘Paracetamol use in pregnancy — caution over causal inference from available data’; ‘Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy’
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., M. Andrade, A., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 3, p. 192 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Reply to ‘Paracetamol use in pregnancy — neglecting context promotes misinterpretation’
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 1 p., 386.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Role of ATP and P2X7 receptor in pancreatic cancer
Magni, Lara, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 151 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase
Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials
Pilmark, N. S., Oberholzer, L., Halling, Jens Frey, Kristensen, Jonas Møller, Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, Jesper Bratz, Larsen, E. L., Meinild-Lundby, A., Wojtaszewski, Jørgen F P, Pilegaard, Henriette, Poulsen, H., Pedersen, Bente Klarlund, Hansen, K. B. & Karstoft, Kristian, 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models
Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sodium, Glucose and Dysregulated Glucagon Secretion: The Potential of Sodium Glucose Transporters
Armour, Sarah Louise, Frueh, A. & Knudsen, Jakob Grunnet, 2022, In: Frontiers in Pharmacology. 13, 6 p., 837664.Research output: Contribution to journal › Review › Research › peer-review
- Published
Structural basis of ion uptake in copper-transporting P1B-type ATPases
Salustros, N., Gronberg, C., Abeyrathna, N. S., Lyu, Pin, Oradd, F., Wang, Kaituo, Andersson, M., Meloni, G. & Gourdon, Pontus Emanuel, 2022, In: Nature Communications. 13, 1, 11 p., 5121.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure and functional analysis of PIB-type ATPases
Lyu, Pin, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 281 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Targeted removal of mitochondrial DNA from mouse and human extrachromosomal circular DNA with CRISPR-Cas9
Feng, Weijia, Arrey Tané, Gerard, Zole, Egija, Iv, W., Liang, Xue, Han, Peng, Mohiyuddin, M., Pilegaard, Henriette & Regenberg, Birgitte, 2022, In: Computational and Structural Biotechnology Journal. 20, p. 3059-3067 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The FASTQ+ format and PISA
Shi, Quan, Liu, S., Kristiansen, Karsten & Liu, L., 2022, In: Bioinformatics. 38, 19, p. 4639-4642 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca2+-Independent Manner
Schnipper, J., Kouba, S., Hague, F., Girault, A., Rybarczyk, P., Telliez, M., Guenin, S., Tebbakha, R., Sevestre, H., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: International Journal of Molecular Sciences . 23, 14, 20 p., 7923.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of water coordination in the pH-dependent gating of hAQP10
Truelsen, S. F., Missel, Julie Winkel, Gotfryd, K., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel, Lindorff-Larsen, Kresten & Hélix-Nielsen, C., 2022, In: B B A - Biomembranes. 1864, 1, 13 p., 183809.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of paracetamol during pregnancy: A qualitative study and possible strategies for a clinical trial
Vedel, C., Jørgensen, D. S., Kristensen, D. M., Petersen, Olav Bennike Bjørn & Greisen, Gorm, 2022, In: PLoS ONE. 17, e0271537.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-dependent regulation of hepatic cytochrome P450 mRNA in male liver-specific PGC-1α knockout mice
Sundekilde, U. K., Kristensen, C. M., Olsen, M. A., Pilegaard, Henriette & Rasmussen, M. K., 2022, In: Toxicology. 469, 8 p., 153121.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic Profile of the Mouse Postnatal Liver Development by Single-Nucleus RNA Sequencing
Xu, J., Hao, S., Shi, Q., Deng, Q., Jiang, Y., Guo, P., Yuan, Y., Shi, X., Shangguan, S., Zheng, H., Lai, G., Huang, Y., Wang, Y., Song, Y., Liu, Y., Wu, L., Wang, Z., Cheng, J., Wei, X., Cheng, M. & 6 others, , 2022, In: Frontiers in Cell and Developmental Biology. 10, 11 p., 833392.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis
Shen, J. X., Couchet, M., Dufau, J., de Castro Barbosa, T., Ulbrich, M. H., Helmstädter, M., Kemas, A. M., Zandi Shafagh, R., Marques, M., Hansen, Jacob B., Mejhert, N., Langin, D., Rydén, M. & Lauschke, V. M., 2021, In: Advanced Science. 8, 16, 17 p., 2100106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Butyribacter intestini gen. nov., sp. nov., a butyric acid-producing bacterium of the family Lachnospiraceae isolated from human faeces, and reclassification of Acetivibrio ethanolgignens as Acetanaerobacter ethanolgignens gen. nov., comb. nov
Zou, Y., Xue, W., Lin, X., Lv, M., Luo, G., Dai, Y., Sun, H., Liu, S., Sun, C., Hu, T. & Xiao, L., 2021, In: Systematic and Applied Microbiology. 44, 3, 8 p., 126201.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins
Preisler, Sarah Spruce, Wiuf, A. D., Friis, M., Kjaergaard, L., Hurd, M., Becares, E. R., Nurup, C. N., Bjoerkskov, F. B., Szathmáry, Z., Gourdon, Pontus Emanuel, Callø, Kirstine, Klærke, Dan Arne, Gotfryd, K. & Pedersen, Per Amstrup, 2021, In: Current research in structural biology. 3, p. 51-71 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ALMS1 Regulates TGF-β Signaling and Morphology of Primary Cilia
Álvarez-Satta, M., Lago-Docampo, M., Bea-Mascato, B., Solarat, C., Castro-Sánchez, S., Christensen, Søren Tvorup & Valverde, D., 2021, In: Frontiers in Cell and Developmental Biology. 9, 8 p., 623829.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Expanded Gene Catalog of Mouse Gut Metagenomes
Zhu, J., Ren, H., Zhong, H., Li, Xiaoping, Zou, Y., Han, Mo, Li, M., Madsen, L., Kristiansen, Karsten & Xiao, L., 2021, In: mSphere. 6, 1, 12 p., e-01119-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes
Kim, A., Knudsen, J. G., Madara, J. C., Benrick, A., Hill, T. G., Kadir, L. A., Kellard, J. A., Mellander, L., Miranda, C., Lin, H., James, T., Suba, K., Spigelman, A. F., Wu, Y., Macdonald, P. E., Asterholm, I. W., Magnussen, T., Christensen, M., Vilsbøll, T., Salem, V. & 4 others, , 2021, In: eLife. 10, 29 p., e72919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
August Krogh's contribution to the rise of physiology during the first half the 20th century
Larsen, Erik Hviid, Hoffmann, E., Hedrick, M. S. & Wang, T., 2021, In: Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology. 256, 7 p., 110931.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
Gonçalves, A. B., Hasselbalch, S. K., Joensen, B. B., Patzke, S., Martens, P., Ohlsen, S. K., Quinodoz, M., Nikopoulos, K., Suleiman, R., Jeppesen, M. P. D., Weiss, C., Christensen, Søren Tvorup, Rivolta, C., Andersen, J. S., Farinelli, P. & Pedersen, Lotte Bang, 2021, In: eLife. 10, 34 p., e63731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine
Christensen, S. L., Rasmussen, R. H., Ernstsen, C., La Cour, S., David, A., Chaker, J., Haanes, K. A., Christensen, Søren Tvorup, Olesen, Jes & Kristensen, D. M., 2021, In: Cephalalgia. 41, 14, p. 1413-1426 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calmodulin downregulation in conditional knockout HeLa cells inhibits cell migration
Alcalde, J., Munk, M., González-Muñoz, M., Panina, S., Berchtold, Martin Werner & Villalobo, A., 2021, In: Archives of Biochemistry and Biophysics. 697, 9 p., 108680.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cervicovaginal microbiome dynamics after taking oral probiotics
Chen, Chen, Hao, L., Zhang, Z., Tian, L., Zhang, X., Zhu, J., Jie, Zhuye, Tong, X., Xiao, L., Zhang, T., Jin, X., Xu, X., Yang, H., Wang, J., Kristiansen, Karsten & Jia, H., 2021, In: Journal of Genetics and Genomics. 48, 8, p. 716-726 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization and description of Faecalibacterium butyricigenerans sp. nov. and F. longum sp. nov., isolated from human faeces
Zou, Y., Lin, X., Xue, W., Tuo, L., Chen, M., Chen, X., Sun, C., Li, F., Liu, S., Dai, Y., Kristiansen, Karsten & Xiao, L., 2021, In: Scientific Reports. 11, 13 p., 11340.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deconstructing transcriptional variations and their effects on immunomodulatory function among human mesenchymal stromal cells
Sun, C., Zhang, K., Yue, J., Meng, S. & Zhang, X., 2021, In: Stem Cell Research & Therapy. 12, 16 p., 53.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen
Rønnov-Jessen, Lone, Kim, Jiyoung, Goldhammer, N., Klitgaard, M. C., Smicius, M., Bechmann, M. B., Villadsen, René & Petersen, Ole William, 2021, In: Scientific Reports. 11, 7 p., 17232.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic Na+/H+ exchanger 1 (NHE1) - calmodulin complexes of varying stoichiometry and structure regulate Ca2+-dependent NHE1 activation
Sjøgaard-Frich, Lise Margrethe, Prestel, Andreas, Pedersen, E. S., Severin, M., Kristensen, Kristian Kølby, Olsen, Johan Gotthardt, Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2021, In: eLife. 10, 29 p., e60889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., Agostinis, P. & 2,908 others, , 2021, In: Autophagy. 17, p. 1-382 382 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
High metabolic substrate load induces mitochondrial dysfunction in rat skeletal muscle microvascular endothelial cells
Hansen, Camilla Collin, Olsen, K., Pilegaard, Henriette, Bangsbo, Jens, Gliemann, Lasse & Hellsten, Ylva, 2021, In: Physiological Reports. 9, 14, 17 p., e14855.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, , 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of irreversible aquaporin-10 inhibition by organogold compounds studied by combined biophysical methods and atomistic simulations
Pimpão, C., Wragg, D., Bonsignore, R., Aikman, B., Pedersen, Per Amstrup, Leoni, S., Soveral, G. & Casini, A., 2021, In: Metallomics. 13, 9, 11 p., mfab053.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic reprogramming by driver mutation-tumor microenvironment interplay in pancreatic cancer: new therapeutic targets
Andersen, Henriette Berg, Ialchina, Renata, Pedersen, Stine Helene Falsig & Czaplinska, D., 2021, In: Cancer and Metastasis Reviews. 40, 4, p. 1093-1114 22 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome
Liu, X., Tong, X., Zhu, J., Tian, L., Jie, Z., Zou, Y., Lin, X., Liang, H., Li, W., Ju, Y., Qin, Y., Zou, L., Lu, H., Zhu, S., Jin, X., Xu, X., Yang, H., Wang, J., Zong, Y., Liu, W. & 3 others, , 2021, In: Cell Discovery. 7, 16 p., 117.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-acetylcysteine protects ovarian follicles from ischemia-reperfusion injury in xenotransplanted human ovarian tissue
Olesen, H. Ø., Pors, S. E., Jensen, L. B., Grønning, A. P., Lemser, C. E., Heimbürger, M. T. H. N., Mamsen, L. S., Getreu, N., Christensen, Søren Tvorup, tcg964, tcg964 & Kristensen, S. G., 2021, In: Human Reproduction. 36, 2, p. 429-443 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neurokinins and their receptors in the rat trigeminal system: Differential localization and release with implications for migraine pain
Edvinsson, J. C., Reducha, Philip Victor, Sheykhzade, Majid, Warfvinge, K., Haanes, Kristian Agmund & Edvinsson, L., 2021, In: Molecular Pain. 17, p. 1-11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New insights into survival strategies of tardigrades
Møbjerg, Nadja & Neves, R., 2021, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 254, 6 p., 110890.Research output: Contribution to journal › Review › Research › peer-review
- Published
New records on the rich loriciferan fauna of Trezen ar Skoden (Roscoff, France): Description of two new species of Nanaloricus and the new genus Scutiloricus
Neves, R. C., Kristensen, Reinhardt Møbjerg & Møbjerg, Nadja, 2021, In: PLoS ONE. 16, 5, 42 p., e0250403.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Occipital Horn Syndrome as a Result of Splice Site Mutations in ATP7A. No Activity of ATP7A Splice Variants Missing Exon 10 or Exon 15
Møller, L. B., Mogensen, M., Weaver, D. D. & Pedersen, Per Amstrup, 2021, In: Frontiers in Molecular Neuroscience. 14, 12 p., 532291.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Order and disorder - An integrative structure of the full-length human growth hormone receptor
Kassem, N., Araya-Secchi, R., Bugge, K., Barclay, A., Steinocher, H., Khondker, A., Wang, Y., Lenard, A. J., Bürck, J., Sahin, Cagla, Ulrich, A. S., Landreh, M., Pedersen, Martin Cramer, Rheinstädter, M. C., Pedersen, Per Amstrup, Lindorff-Larsen, Kresten, Arleth, Lise & Kragelund, Birthe Brandt, 2021, In: Science Advances. 7, 27, 20 p., eabh3805.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overproduction of Human Zip (SLC39) Zinc Transporters in Saccharomyces cerevisiae for Biophysical Characterization
Becares, E. R., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2021, In: Cells. 10, 2, 21 p., 213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Paracetamol use during pregnancy — a call for precautionary action
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2021, In: Nature Reviews Endocrinology. 17, p. 757–766 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Parathyroid hormone receptor stimulation induces human adipocyte lipolysis and browning
Breining, P., Pedersen, S. B., Kjolby, M., Hansen, Jacob B., Jessen, N. & Richelsen, B., 2021, In: European Journal of Endocrinology. 184, 5, p. 687-697 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer
Rolver, M. G. & Pedersen, Stine Helene Falsig, 2021, In: British Journal of Cancer. 124, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Recombinant production of membrane proteins in yeast
Preisler, Sarah Spruce, Hansen, K. M., Nurup, C. N., Beich-Frandsen, M. & Pedersen, Per Amstrup, 2021, Methods in Enzymology. Pyle, A. M. & Christianson, D. W. (eds.). Academic Press, Vol. 660. p. 21-52 32 p. (Methods in Enzymology, Vol. 660).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure
Chen, W., Weng, Z., Xie, Z., Xie, Y., Zhang, C., Chen, Z., Ruan, F., Wang, J., Sun, Y., Fang, Y., Guo, M., Tong, Y., Li, Y. & Tang, C., 2021, In: Epigenetics & Chromatin. 14, 11 p., 40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Taxonomic Description and Genome Sequence of Christensenella intestinihominis sp. nov., a Novel Cholesterol-Lowering Bacterium Isolated From Human Gut
Zou, Y., Xue, W., Lin, X., Hu, T., Liu, S., Sun, C., Luo, G., Lv, M., Dai, Y., Kristiansen, Karsten & Xiao, L., 2021, In: Frontiers in Microbiology. 12, 13 p., 632361.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer
Pedersen, Stine Helene Falsig, Flinck, M. & Pardo, L. A., 2021, In: International Journal of Molecular Sciences. 22, 10, 27 p., 5209.Research output: Contribution to journal › Review › Research › peer-review
- Published
The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells
Magni, Lara, Bouazzi, R., Heredero Olmedilla, H., Petersen, P. S. S., Tozzi, M. & Novak, Ivana, 2021, In: Cells. 10, 8, 20 p., 1928.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells
Doray, A., Lemoine, R., Severin, M., Chadet, S., Lopez-Charcas, O., Héraud, A., Baron, C., Besson, P., Monteil, A., Pedersen, Stine Helene Falsig & Roger, S., 2021, In: Cells. 10, 7, 15 p., 1624.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The heart arrhythmia-linked D130G calmodulin mutation causes premature inhibitory autophosphorylation of CaMKII
Berchtold, Martin Werner, Munk, M., Kulej, K., Porth, I., Lorentzen, Lasse Gøbel, Panina, S., Zacharias, T., Larsen, M. R. & la Cour, J. M., 2021, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1868, 12, 9 p., 119119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells
Sun, C., Wang, H., Ma, Q., Chen, C., Yue, J., Li, B. & Zhang, X., 2021, In: Cell and Bioscience. 11, 12 p., 24.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment
Fontenete, S., Lerche, Catharina Margrethe, Paasch, U., Perez-Moreno, Mirna, Olesen, U. H. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity
Hendus-Altenburger, R., Vogensen, J., Pedersen, E. S., Luchini, A., Araya-Secchi, R., Bendsoe, A. H., Prasad, N. S., Prestel, Andreas, Cardenas, M., Pedraz-Cuesta, E., Arleth, Lise, Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 3 Dec 2020, In: Communications Biology . 3, 1, 18 p., 731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation
Fontenete, S., Christensen, J., Martinez-Silgado, A., Zarzuela, E., Muñoz, J., Megias, D., Castellana, D., Loewe, R. & Perez-Moreno, Mirna, 18 Jul 2020, bioRxiv, 58 p. (bioRxiv).Research output: Working paper › Preprint › Research
- Published
The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4
Thiesen, L., Belew, Zeinu Mussa, Griem-Krey, Nane, Pedersen, Stine Helene Falsig, Crocoll, C., Nour-Eldin, Hussam Hassan & Wellendorph, Petrine, 15 Feb 2020, In: European Journal of Pharmaceutical Sciences. 143, p. 1-9 105203.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ciliary Localization of the Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis
Stevens, E. M., Vladar, E. K., Alanin, M. C., Christensen, Søren Tvorup, von Buchwald, Christian & Milla, C., Jan 2020, In: American Journal of Respiratory Cell and Molecular Biology. 62, 1, p. 120-123 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of caveolin in primary cilia
Morthorst, Stine Kjær, Mogensen, J. B., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2020, Caveolae: Methods and Protocols. Blouin, C. M. (ed.). Humana Press, p. 27-41 (Methods in Molecular Biology, Vol. 2169).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion
Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-1 and Not Beta-3 Adrenergic Receptors May Be the Primary Regulator of Human Brown Adipocyte Metabolism
Riis-Vestergaard, M. J., Richelsen, B., Bruun, J. M., Li, W., Hansen, Jacob B. & Pedersen, S. B., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, 12 p., dgz298.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biophysical characterization and industrial-scale production of Aquaporins: Human aquaporins in relation to lifestyle disease and identification of putative aquaporins for improved water filtration
Krabbe, S. L., 2020, Department of Biology, Faculty of Science, University of Copenhagen. 216 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival
Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circle-Seq: Isolation and Sequencing of Chromosome-Derived Circular DNA Elements in Cells
Møller, H. D., 2020, DNA Electrophoresis: Methods and Protocols. Hanada, K. (ed.). Humana Press, p. 165-181 17 p. (Methods in Molecular Biology, Vol. 2119).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner
Buch, B. T., Halling, Jens Frey, Jørgensen, Stine Ringholm, Gudiksen, Anders, Kjøbsted, Rasmus, Olsen, M. A., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2020, In: F A S E B Journal. 34, 6, p. 8653-8670Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends
Serra-Marques, A., Martin, M., Katrukha, E. A., Grigoriev, I., Peeters, C. A. E., Liu, Q., Hooikaas, P. J., Yao, Y., Solianova, V., Smal, I., Pedersen, Lotte Bang, Meijering, E., Kaitein, L. C. & Akhmanova, A., 2020, In: eLife. 9, 37 p., e61302.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Description, redescription and revision of sixteen putatively closely related species of Echinoderes (Kinorhyncha: Cyclorhagida), with the proposition of a new species group - the Echinoderes dujardinii group
Sørensen, Martin Vinther, Goetz, F. E., Herranz, Maria, Chang, C. Y., Chatterjee, T., Durucan, F., Neves, R. C., Yildiz, N. Ö., Norenburg, J. & Yamasaki, H., 2020, In: European Journal of Taxonomy. 730, p. 1-101 101 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of insulin on natriuretic peptide gene expression in porcine heart
Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise: from physiology to bedside to physiology
Han, J., Neufer, D. & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 135Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Fibroblasts direct differentiation of human breast epithelial progenitors
Morsing, M., Kim, Jiyoung, Villadsen, René, Goldhammer, N., Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2020, In: Breast Cancer Research. 22, 16 p., 102.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional characterization of the first missense variant in CEP78, a founder allele associated with cone-rod dystrophy, hearing loss and reduced male fertility
Ascari, G., Peelman, F., Farinelli, P., Rosseel, T., Lambrechts, N., Wunderlich, K. A., Wagner, M., Nikopoulos, K., Martens, P., Balikova, I., Derycke, L., Holtappels, G., Krysko, O., Van Laethem, T., De Jaegere, S., Guillemyn, B., De Rycke, R., De Bleecker, J., Creytens, D., Van Dorpe, J. & 11 others, , 2020, In: Human Mutation. 41, 5, p. 998-1011 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fundamentals of Bicarbonate Secretion in Epithelia
Novak, Ivana & Praetorius, J., 2020, Basic Epithelial Ion TransportPrinciples and Function: Ion Channels and Transporters of Epitheliain Health and Disease. Hamilton, K. L. & Devor, D. C. (eds.). 2. ed. Springer, Vol. 1. p. 461-541 (Physiology in Health and Disease).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Hepatic PGC-1α is not essential for fasting-induced cytochrome p450 regulation in mouse liver
Thøgersen, R., Maag Kristensen, C., Olsen, M. A., Bertram, H. C., Pilegaard, Henriette & Rasmussen, M. K., 2020, In: Biochemical Pharmacology. 172, 7 p., 113736.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution
Björkman, A., Johansen, S. L., Lin, L., Schertzer, M., Kanellis, D. C., Katsori, A., Christensen, Søren Tvorup, Luo, Y., Andersen, J. S., Elsässer, S. J., Londono-Vallejo, A., Bartek, J. & Schou, K. B., 2020, In: Genes & Development. 34, 15-16, p. 1065-1074 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of skeletal muscle IL-6 on subcutaneous and visceral adipose tissue metabolism immediately after high- and moderate-intensity exercises
Bertholdt, L., Gudiksen, Anders, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 217-233 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of the histone deacetylase inhibitor trichostatin A on active uptake, volume-sensitive release of taurine, and cell fate in human ovarian cancer cells
Lambert, Ian Henry, Nielsen, D. & Stürup, Stefan, 2020, In: American journal of physiology. Cell physiology. 318, 3, p. C581-C597Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise
Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, , 2020, In: Molecular Metabolism. 40, 17 p., 101028.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2x2 factorial, randomised, crossover study in human individuals
Hjelholt, A. J., Charidemou, E., Griffin, J. L., Pedersen, S. B., Gudiksen, Anders, Pilegaard, Henriette, Jessen, N., Møller, N. & Jørgensen, J. O. L., 2020, In: Diabetologia. 63, 12, p. 2641-2653 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New insights into the limited thermotolerance of anhydrobiotic tardigrades
Cardoso Neves, R. A., Stuart, R. M. & Møbjerg, Nadja, 2020, In: Communicative & Integrative Biology. 13, 1, p. 140-146Research output: Contribution to journal › Letter › Research › peer-review
- Published
O-glycan initiation directs distinct biological pathways and controls epithelial differentiation
Bagdonaite, Ieva , Pallesen, E. M. H., Ye, Z., Vakhrushev, Sergey, Marinova, I. N., Nielsen, Mathias Alexander Ingemann, Kramer, S. H., Pedersen, Stine Helene Falsig, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2020, In: EMBO Reports. 21, 6, 17 p., e48885.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ongoing revision of Echiniscoididae (Heterotardigrada: Echiniscoidea), with the description of a new interstitial species and genus with unique anal structures
Møbjerg, Nadja, Jørgensen, Aslak & Kristensen, Reinhardt Møbjerg, 2020, In: Zoological Journal of the Linnean Society . 188, 3, p. 663-680 18 p., zlz122.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PGC-1α-mediated regulation of mitochondrial function and physiological implications
Halling, Jens Frey & Pilegaard, Henriette, 2020, In: Applied Physiology, Nutrition and Metabolism. 45, 9, p. 927-936 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration
Tozzi, M., Hansen, Jacob B. & Novak, Ivana, 2020, In: Acta Physiologica. 228, 2, 18 p., e13360.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proton Pump Inhibitors Reduce Pancreatic Adenocarcinoma Progression by Selectively Targeting H+, K+-ATPases in Pancreatic Cancer and Stellate Cells
Tozzi, M., Sørensen, Christiane Elisabeth, Magni, Lara, Christensen, Nynne, Bouazzi, R., Buch, C. M., Stefanini, M., Duranti, C., Arcangeli, A. & Novak, Ivana, 2020, In: Cancers. 12, 3, 22 p., 640.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Purification and initial characterization of Plasmodium falciparum K+ channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae
Molbaek, K., Tejada, M., Ricke, C. H., Scharff-Poulsen, P., Ellekvist, P., Helix-Nielsen, C., Kumar, N., Klærke, Dan Arne & Pedersen, Per Amstrup, 2020, In: Microbial Cell Factories. 19, 1, 183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Purinergic Signaling in Pancreas - From Physiology to Therapeutic Strategies in Pancreatic Cancer
Novak, Ivana, Yu, Haoran, Magni, Lara & Deshar, Ganga, 2020, In: International Journal of Molecular Sciences (Online). 21, 22, 21 p., 8781.Research output: Contribution to journal › Review › Research › peer-review
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Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer
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Cell volume regulation in epithelial physiology and cancer
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
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GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion
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