Cell Biology and Physiology

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  1. 2020
  2. Published

    Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1

    Rolver, M. G., Elingaard-Larsen, L. O., Andersen, Anne Poder, Counillon, L. & Pedersen, Stine Helene Falsig, 2020, In: Scientific Reports. 10, 17 p., 5800.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes

    Isidor, Marie Sophie, Winther, Sally, Markussen, L. K., Basse, A. L., Quistorff, B., Nedergaard, J., Emanuelli, Brice & Hansen, Jacob B., 2020, In: FEBS Letters. 594, 7, p. 1218-1225

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

    Farooq, M., Lindbæk, L., Krogh, N., Doganli, C., Keller, C., Mönnich, M., Gonçalves, A. B., Sakthivel, S., Mang, Y., Fatima, A., Andersen, V. S., Hussain, M. S., Eiberg, H., Hansen, L., Kjaer, K. W., Gopalakrishnan, J., Pedersen, L. B., Møllgård, K., Nielsen, H., Baig, S. M. & 3 others, Tommerup, Niels, Christensen, Søren Tvorup & Larsen, Lars Allan, 2020, In: Nature Communications. 11, 16 p., 5816.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet

    Kellard, J. A., Rorsman, N. J. G., Hill, T. G., Armour, Sarah Louise, van de Bunt, M., Rorsman, P., Knudsen, Jakob Grunnet & Briant, L. J. B., 2020, In: Molecular Metabolism. 40, 13 p., 101021.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae

    Prada Luengo, Inigo, Møller, H. D., Henriksen, Rasmus Henrik Amund, Gao, Q., Larsen, C. E., Alizadeh, S., Maretty, L., Houseley, J. & Regenberg, Birgitte, 2020, In: Nucleic Acids Research. 48, 14, p. 7883-7898 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Research presented at the 14th International Symposium on Tardigrada: progress in studies on water bears

    Møbjerg, Nadja, Michalczyk, Ł., McInnes, S. J. & Christenhusz, M. J. M., 2020, In: Zoological Journal of the Linnean Society . 188, 3, p. 655-662

    Research output: Contribution to journal › Editorial › Research › peer-review

  8. Published

    Sprifermin (rhFGF18) versus vehicle induces a biphasic process of extracellular matrix remodeling in human knee OA articular cartilage ex vivo

    Reker, D., Siebuhr, A. S., Thudium, C. S., Gantzel, T., Ladel, C., Michaelis, M., Aspberg, A., Berchtold, Martin Werner, Karsdal, M. A., Gigout, A. & Bay-Jensen, A. C., 2020, In: Scientific Reports. 10, 9 p., 6011.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The Acidic Tumor Microenvironment as a Driver of Cancer

    Boedtkjer, E. & Pedersen, Stine Helene Falsig, 2020, In: Annual Review of Physiology. 82, p. 103-126

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets

    Ghiasi, S. M., Hansen, J. B., Christensen, D. P., Tyrberg, B. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences (Online). 21, 12, 15 p., 4311.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis

    Villalobo, A. & Berchtold, Martin Werner, 2020, In: International Journal of Molecular Sciences (Online). 21, 3, 42 p., 765.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    The Vacuolar H+ ATPase α3 Subunit Negatively Regulates Migration and Invasion of Human Pancreatic Ductal Adenocarcinoma Cells

    Flinck, M., Hagelund, S., Gorbatenko, A., Severin, M., Pedraz-Cuesta, E., Novak, Ivana, Stock, C. & Pedersen, Stine Helene Falsig, 2020, In: Cells. 9, 2, 22 p., 465.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The autocrine role of FGF21 in cultured adipocytes

    Justesen, S., Haugegaard, K. V., Hansen, Jacob B., Hansen, Harald S. & Andersen, B., 2020, In: The Biochemical journal. 477, 13, p. 2477-2487 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The impact of calmodulin on the cell cycle analyzed in a novel human cellular genetic system

    Munk, M., Alcalde, J., Lorentzen, Lasse Gøbel, Villalobo, A., Berchtold, Martin Werner & Panina, S., 2020, In: Cell Calcium. 88, 8 p., 102207.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The rapid “teabag” method for high-end purification of membrane proteins

    Hering, J., Missel, Julie Winkel, Zhang, L., Gunnarsson, A., Castaldo, M., Pedersen, Per Amstrup, Ek, M., Gourdon, Pontus Emanuel & Snijder, H. J., 2020, In: Scientific Reports. 10, 11 p., 16167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Thermotolerance experiments on active and desiccated states of Ramazzottius varieornatus emphasize that tardigrades are sensitive to high temperatures

    Neves, R. C., Hvidepil, L. K. B., Sørensen-Hygum, T. L., Stuart, R. M. & Møbjerg, Nadja, 2020, In: Scientific Reports. 10, 12 p., 94.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Update of P2Y receptor pharmacology: IUPHAR Review 27

    Jacobson, K. A., Delicado, E. G., Gachet, C., Kennedy, C., von Kügelgen, I., Li, B., Miras-Portugal, M. T., Novak, Ivana, Schöneberg, T., Perez-Sen, R., Thor, D., Wu, B., Yang, Z. & Müller, C. E., 2020, In: British Journal of Pharmacology. 177, 11, p. 2413-2433 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Volume Regulation in Epithelia

    Larsen, Erik Hviid & Hoffmann, E. K., 2020, Ion Channels and Transporters of Epitheliain Health and Disease. Hamilton, K. L. & Devor, D. C. (eds.). 2 ed. Springer, Vol. 1. p. 395-460 (Physiology in Health and Disease).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    Why Warburg Works: Lactate Controls Immune Evasion through GPR81

    Jørgensen, Kathrine Lundø, Trauelsen, Mette, Pedersen, Stine Helene Falsig & Schwartz, Thue W., 2020, In: Cell Metabolism. 31, 4, p. 666–668 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  21. Published

    Yeast recombinant production of intact human membrane proteins with long intrinsically disordered intracellular regions for structural studies

    Kassem, N., Kassem, M. M., Pedersen, Stine Helene Falsig, Pedersen, Per Amstrup & Kragelund, Birthe Brandt, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 14 p., 183272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    m6A-dependent biogenesis of circular RNAs in male germ cells

    Tang, C., Xie, Y., Yu, T., Liu, N., Wang, Z., Woolsey, R. J., Tang, Y., Zhang, X., Qin, W., Zhang, Y., Song, G., Zheng, W., Wang, J., Chen, W., Wei, X., Xie, Z., Klukovich, R., Zheng, H., Quilici, D. R. & Yan, W., 2020, In: Cell Research. 30, p. 211-228 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2019
  24. Published

    3D multicellular models to study the regulation and roles of acid-base transporters in breast cancer

    Czaplinska, D., Elingaard-Larsen, L. O., Rolver, M. G., Severin, M. & Pedersen, Stine Helene Falsig, 20 Dec 2019, In: Biochemical Society Transactions. 47, 6, p. 1689-1700 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses

    Zou, Y., Xue, W., Luo, G., Deng, Z., Qin, P., Guo, R., Sun, H., Xia, Y., Liang, S., Dai, Y., Wan, D., Jiang, R., Su, L., Feng, Q., Jie, Z., Guo, T., Xia, Z., Liu, C., Yu, J., Lin, Y. & 11 others, Tang, S., Huo, G., Xu, X., Hou, Y., Liu, X., Wang, J., Yang, H., Kristiansen, Karsten, Li, J., Jia, H. & Xiao, L., 2019, In: Nature Biotechnology. 37, 2, p. 179-185

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors

    Ísberg, Ó. G., Kim, Jiyoung, Fridriksdottir, A. J., Morsing, M., Timmermans-Wielenga, V., Rønnov-Jessen, Lone, Petersen, Ole William & Villadsen, René, 2019, In: Scientific Reports. 9, 11 p., 14843.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling

    Frikstad, K. M., Molinari, E., Thoresen, M., Ramsbottom, S. A., Hughes, F., Letteboer, S. J. F., Gilani, S., Schink, K. O., Stokke, T., Geimer, S., Pedersen, Lotte Bang, Giles, R. H., Akhmanova, A., Roepman, R., Sayer, J. A. & Patzke, S., 2019, In: Cell Reports. 28, 7, p. 1907-1922, e1-e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A novel missense variant in IDH3A causes autosomal recessive retinitis pigmentosa

    Peter, V. G., Nikopoulos, K., Quinodoz, M., Granse, L., Farinelli, P., Superti-Furga, A., Andreasson, S. & Rivolta, C., 2019, In: Ophthalmic Genetics. 40, 2, p. 177-181

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer

    Avnet, S., Baldini, N., Brisson, L., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Szabadkai, G. & Pastorekova, S., 2019, In: Frontiers in Oncology. 9, 5 p., 1332.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Assessing Cell Viability and Death in 3D Spheroid Cultures of Cancer Cells

    Rolver, M. G., Elingaard-Larsen, L. O. & Pedersen, Stine Helene Falsig, 2019, In: Journal of Visualized Experiments. 2019, 148, e59714.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Cellular signalling by primary cilia in development, organ function and disease

    Anvarian, Zeinab, Mykytyn, K., Mukhopadhyay, S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2019, In: Nature Reviews Nephrology. 15, p. 199-219

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Characterization of Hailey-Hailey Disease-mutants in presence and absence of wild type SPCA1 using Saccharomyces cerevisiae as model organism

    Muncanovic, D., Justesen, M. H., Preisler, Sarah Spruce & Pedersen, Per Amstrup, 2019, In: Scientific Reports. 9, 25 p., 12442.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Comparative myoanatomy of Tardigrada: new insights from the heterotardigrades Actinarctus doryphorus (Tanarctidae) and Echiniscoides sigismundi (Echiniscoididae)

    Persson, D. K., Halberg, Kenneth Veland, Cardoso Neves, R. A., Jørgensen, Aslak, Kristensen, Reinhardt Møbjerg & Møbjerg, Nadja, 2019, In: B M C Evolutionary Biology. 19, 14 p., 206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Comparative transcriptomics suggest unique molecular adaptations within tardigrade lineages

    Kamilari, M., Jørgensen, Aslak, Schiøtt, M. & Møbjerg, Nadja, 2019, In: B M C Genomics. 20, 19 p., 607.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells

    Grubb, Søren, Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, Kjeld, Ernst, E., Christensen, Søren Tvorup, Callø, Kirstine & tcg964, tcg964, 2019, In: Stem Cells and Development. 28, 9, p. 608-619

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Distribution of platinum between nuclear and cytosolic fractions: can subcellular fractionation be performed quantitatively?

    Dam, C. S., Lambert, Ian Henry, Gammelgaard, Bente & Stürup, Stefan, 2019, In: Journal of Pharmaceutical and Biomedical Analysis. 165, p. 82-89 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

    Tornabene, E., Helms, H. C. C., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2019, In: PLoS ONE. 14, 8, 20 p., e0221103.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Exercise physiology: future opportunities and challenges

    Han, J., Neufer, D. & Pilegaard, Henriette, 2019, In: Pflügers Archiv - European Journal of Physiology. 471, 3, p. 381 1 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  39. Published

    Extreme stress tolerance in tardigrade: with a focus on modelling cryptobiotic survival

    Sørensen-Hygum, T. L., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  40. Published

    First report of Loricifera from the North East Pacific Region, with the description of two new species

    Cardoso Neves, R. A., Kristensen, Reinhardt Møbjerg, Rohal, M., Thistle, D. & Sørensen, Martin Vinther, 2019, In: Marine Biodiversity. 49, 3, p. 1151-1168 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

    Gorbatenko, A., Søkilde, R., Sorensen, E. E., Newie, I., Persson, H., Morancho, B., Arribas, J., Litman, Thomas, Rovira, C. & Pedersen, Stine Helene Falsig, 2019, In: Scientific Reports. 9, 1, p. 1-16 3352.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Human aquaporin-5 facilitates hydrogen peroxide permeation affecting adaption to oxidative stress and cancer cell migration

    Rodrigues, C., Pimpão, C., Mósca, A. F., Coxixo, A. S., Lopes, D., Da Silva, I. V., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2019, In: Cancers. 11, 7, 17 p., 932.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Impact of arrhythmogenic calmodulin variants on small conductance Ca2+-activated K+ (SK3) channels

    Saljic, Arnela, Muthukumarasamy, K. M., la Cour, J. M., Boddum, K., Grunnet, Morten, Berchtold, Martin Werner & Jespersen, Thomas, 2019, In: Physiological Reports. 7, 19, 13 p., e14210.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Inclusion of sprints in moderate intensity continuous training leads to muscle oxidative adaptations in trained individuals

    Gunnarsson, T. G. P., Brandt, N., Fiorenza, Matteo, Hostrup, Morten, Pilegaard, Henriette & Bangsbo, Jens, 2019, In: Physiological Reports. 7, 4, 15 p., e13976.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Isolation of cancer stem cells from squamous cell carcinoma

    Fontenete, S. & Perez-Moreno, Mirna, 2019, Skin Stem Cells: Methods and Protocols. Turksen, K. (ed.). 2. ed. ed. Humana Press, p. 407-414 8 p. (Methods in Molecular Biology, Vol. 1879).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  46. Published

    Kinesins 1 and 3 Cooperate on the Same Vesicle to Transport Exocytotic Carriers

    Serra-Marques, A., Martin, M., Katrukha, E., Grigoriev, I., Liu, Q., Pedersen, Lotte Bang, Kapitein, L. & Akhmanova, A., 2019, In: Biophysical Journal. 116, 3, Suppl. 1, p. 309a 1526-Plat.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle

    Sailani, M. R., Halling, Jens Frey, Møller, H. D., Lee, H., Plomgaard, Peter Stendahl, Pilegaard, Henriette, Snyder, M. P. & Regenberg, Birgitte, 2019, In: Scientific Reports. 9, p. 1-11 3272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo

    Peña-Jimenez, D., Fontenete, S., Megias, D., Fustero-Torre, C., Graña-Castro, O., Castellana, D., Loewe, R. & Perez-Moreno, Mirna, 2019, In: EMBO Journal. 38, 19, 17 p., e101688.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin

    Hendus-Altenburger, R., Wang, X., Sjøgaard-Frich, Lise Margrethe, Pedraz Cuesta, E., Sheftic, S. R., Bendsøe, A. H., Page, R., Kragelund, Birthe Brandt, Pedersen, Stine Helene Falsig & Peti, W., 2019, In: Nature Communications. 10, 13 p., 3489.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice

    Danneskiold-Samsøe, Niels Banhos, Sonne, Si Brask, Larsen, J. M., Hansen, Ann Normann, Fjære, E., Isidor, Marie Sophie, Petersen, S., Henningsen, J., Severi, I., Sartini, L., Schobers, Y., Wolf, J., Nockhers, W. A., Wolfrum, C., Cinti, S., Sina, C., Hansen, Jacob B., Madsen, L., Brix, S. & Kristiansen, Karsten, 2019, In: Scientific Reports. 9, 13 p., 8979.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training

    Halling, Jens Frey, Jessen, H., Nøhr-Meldgaard, J., Buch, B. T., Christensen, N. M., Gudiksen, Anders, Jørgensen, Stine Ringholm, Neufer, P. D., Prats Gavalda, Clara & Pilegaard, Henriette, 2019, In: American journal of physiology. Endocrinology and metabolism. 317, 3, p. E513-E525

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Possible link between FSH and RANKL release from adipocytes in men with impaired gonadal function including Klinefelter syndrome

    Mortensen, L. J., Lorenzen, M., Jørgensen, N., Andersson, A., Nielsen, J. E., Petersen, L. I., Lanske, B., Juul, Anders, Hansen, Jacob B. & Jensen, M. B., 2019, In: Bone. 123, p. 103-114

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Profibrotic epithelial phenotype: a central role for MRTF and TAZ

    Bialik, J. F., Ding, M., Speight, P., Dan, Q., Miranda, M. Z., Di Ciano-Oliveira, C., Kofler, M. M., Rotstein, O. D., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2019, In: Scientific Reports. 9, p. 1-14 4323.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Proteins with calmodulin-like domains: structures and functional roles

    Villalobo, A., González-Muñoz, M. & Berchtold, Martin Werner, 2019, In: Cellular and Molecular Life Sciences. 76, 12, p. 2299-2328

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

    Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Redundancy in regulation of lipid accumulation in skeletal muscle during prolonged fasting in obese men

    Høgild, M. L., Gudiksen, Anders, Pilegaard, Henriette, Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Jørgensen, J. O. L. & Jessen, N., 2019, In: Physiological Reports. 7, 21, 15 p., e14285.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Regulation and structural aspects of the human Na+/H+ exchanger NHE1: Roles of the N-terminal region and interactions with lipids

    Vogensen, J., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  58. Published

    Role of the P2X7 receptor in the pathogenesis of type 2 diabetes and its microvascular complications

    Solini, A. & Novak, Ivana, 2019, In: Current Opinion in Pharmacology. 47, p. 75-81 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  59. Published

    Skeletal muscle interleukin 6 in fasting and exercise-induced metabolic regulation in liver and adipose tissue

    Bertholdt, L., 2019, Department of Biology, Faculty of Science, University of Copenhagen. 179 p.

    Research output: Book/Report › Ph.D. thesis › Research

  60. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    The Na+/H+ exchanger NHE1 localizes as clusters to cryptic lamellipodia and accelerates collective epithelial cell migration

    Jensen, H. H., Pedersen, G. A., Morgen, J. J., Parsons, M., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2019, In: Journal of Physiology. 597, 3, p. 849-867

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    The SLC9A-C Mammalian Na+/H+ Exchanger Family: Molecules, Mechanisms, and Physiology

    Pedersen, Stine Helene Falsig & Counillon, L., 2019, In: Physiological Reviews. 99, 4, p. 2015-2113 99 p.

    Research output: Contribution to journal › Review › Research › peer-review

  63. 2018
  64. Published

    Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

    Møller, H. D., Mohiyuddin, M., Prada Luengo, Inigo, Sailani, M. R., Halling, Jens Frey, Plomgaard, Peter Stendahl, Maretty, L., Hansen, Anders Johannes, Snyder, M. P., Pilegaard, Henriette, Lam, H. Y. K. & Regenberg, Birgitte, 1 Dec 2018, In: Nature Communications. 9, 12 p., 1069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers

    Kjeld, T., Stride, N., Gudiksen, Anders, Hansen, E. G., Arendrup, H. C., Horstmann, P. F., Zerahn, B., Jensen, Lars Thorbjørn, Nordsborg, Nikolai Baastrup, Bejder, Jacob & Halling, Jens Frey, 19 Sep 2018, In: P L o S One. 13, 9, p. 1-13 13 p., e0201401.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Facilitating the Cellular Accumulation of Pt-Based Chemotherapeutic Drugs

    Lambert, Ian Henry & Sørensen, B. H., 1 Aug 2018, In: International Journal of Molecular Sciences . 19, 8, p. 1-19 2249.

    Research output: Contribution to journal › Review › Research › peer-review

  68. Published

    Genetic Analysis of Signal Generation by the Rgt2 Glucose Sensor of Saccharomyces cerevisiae

    Scharff-Poulsen, P., Moriya, H. & Johnston, M., 1 Aug 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 8, p. 2685-2696 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle

    Brandt, N., Nielsen, L., Buch, B. T., Gudiksen, Anders, Jørgensen, Stine Ringholm, Hellsten, Ylva, Bangsbo, Jens & Pilegaard, Henriette, 1 Jan 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E1-E20 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(II) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis

    Sørensen, B. H., Werth, P., Lambert, Ian Henry & Bednarski, P. J., 2018, In: Metallomics. 10, 2, p. 323-336 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment

    la Cour, J. M., Gojkovic, P. W., Ambjorner, S. E. B., Bagge, J., Jensen, S. M., Panina, S. & Berchtold, Martin Werner, 2018, In: PLOS ONE. 13, 9, p. 1-13 e0204520.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2

    Højfeldt, J. W., Laugesen, A., Willumsen, Berthe Marie, Damhofer, H., Hedehus, L., Tvardovskiy, A., Mohammad, F., Jensen, O. N. & Helin, K., 2018, In: Nature Structural & Molecular Biology. 25, p. 225-232 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

    Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  74. Published

    Beta2-adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men

    Hostrup, Morten, Reitelseder, S., Jessen, Søren Kaare, Kalsen, A., Nyberg, M. P., Egelund, J., Kreiberg, M., Maag Kristensen, C., Thomassen, Martin, Pilegaard, Henriette, Backer, Vibeke, Jacobson, G. A., Holm, L. & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 17, p. 4121-4139 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    CRISPR-C: circularization of genes and chromosome by CRISPR in human cells

    Møller, H. D., Lin, L., Xiang, X., Petersen, T. S., Huang, J., Yang, L., Kjeldsen, E., Jensen, U. B., Zhang, X., Liu, X., Xu, X., Wang, J., Yang, H., Church, G. M., Bolund, L., Regenberg, Birgitte & Luo, Y., 2018, In: Nucleic Acids Research. 46, 22, p. 1-13 e131.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Calmodulin as a protein linker and a regulator of adaptor/scaffold proteins

    Villalobo, A., Ishida, H., Vogel, H. J. & Berchtold, Martin Werner, 2018, In: B B A - Molecular Cell Research. 1865, 3, p. 507-521 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  78. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Characterization of Taurine Transporting Systems During Acquirement of Resistance to Platinum(II)-based, Chemotherapeutic Drugs

    Sørensen, B. H., 2018, Department of Biology, Faculty of Science, University of Copenhagen. 190 p.

    Research output: Book/Report › Ph.D. thesis › Research

  80. Published

    Deconstructing the principles of ductal network formation in the pancreas

    Dahl-Jensen, Svend Bertel, Yennek, S., Flasse, L., Larsen, Hjalte List, Sever, D., Karremore, G., Novak, Ivana, Sneppen, Kim & Botton, A., 2018, In: PLOS Biology. 16, 7, 25 p., e2002842.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Development and validation of an ICP-MS method for quantification of total carbon and platinum in cell samples and comparison of open-vessel and microwave-assisted acid digestion methods

    Riisom, M., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 158, p. 144-150 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine

    Rubino, S., Bach, M. D., Schober, A. L., Lambert, Ian Henry & Mongin, A. A., 2018, In: Frontiers in Oncology. 8, 12 p., 142.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Environmental Adaptations: Encystment and Cyclomorphosis

    Guidetti, R. & Møbjerg, Nadja, 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 249-271 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  84. Published

    Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Bangsbo, Jens & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 7, 12 p., e13651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    From channel proteins to industrial biomimetic membrane technology

    Pedersen, Per Amstrup, Bjørkskov, F. B., Alvisse, S. & Hélix-Nielsen, C., 2018, In: Faraday Discussions. 209, p. 287-301 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    GSK3 is a negative regulator of the thermogenic program in brown adipocytes

    Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Human AQP5 facilitates hydrogen peroxide permeation and improves cell resistance to oxidative stress

    Rodrigues, C., Mósca, A. F., Lopes, D., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2018, In: Free Radical Biology and Medicine. 120, Suppl. 1, p. S70 P-86.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  88. Published

    Human adipose glycerol flux is regulated by a pH gate in AQP10

    Gotfryd, K., Mósca, A. F., Missel, Julie Winkel, Truelsen, S. F., Wang, Kaituo, Spulber, M., Krabbe, S., Hélix-nielsen, C., Laforenza, U., Soveral, G., Pedersen, Per Amstrup & Gourdon, Pontus Emanuel, 2018, In: Nature Communications. 9, p. 1-11 4749.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

    Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, Lars Allan, Andersen, J. S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2018, In: Journal of Cell Biology. 217, 1, p. 151-161 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice

    Rasmussen, M. K., Bertholdt, L., Gudiksen, Anders, Pilegaard, Henriette & Knudsen, Jakob Grunnet, 2018, In: Toxicology Letters. 282, p. 93-99 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Impact of liver PGC-1α on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF

    Dethlefsen, M. M., Kristensen, C. M., Tondering, A. S., Lassen, S. B., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 13, p. 1-16 e13731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting

    Bertholdt, L., Gudiksen, Anders, Jessen, H. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1597-1613

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans

    Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Villesen, I., Tybirk, J., van Hall, Gerrit, Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Journal of Applied Physiology. 124, 3, p. 729-740 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Metabolic stress-dependent regulation of the mitochondrial biogenic molecular response to high-intensity exercise in human skeletal muscle

    Fiorenza, Matteo, Gunnarsson, T. P., Hostrup, Morten, Iaia, F. M., Schena, F., Pilegaard, Henriette & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 14, p. 2823-2840 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Metformin targets brown adipose tissue in vivo and reduces oxygen consumption in vitro

    Breining, P., Jensen, J. B., Sundelin, E. I., Gormsen, L. C., Jakobsen, S., Busk, M., Rolighed, L., Bross, P., Fernandez-Guerra, P., Markussen, L. K., Rasmussen, N. E., Hansen, Jacob B., Pedersen, S. B., Richelsen, B. & Jessen, N., 2018, In: Diabetes, Obesity and Metabolism. 20, 9, p. 2264-2273

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Modelling extreme desiccation tolerance in a marine tardigrade

    Sørensen-Hygum, T. L., Stuart, R. M., Jørgensen, Aslak & Møbjerg, Nadja, 2018, In: Scientific Reports. 8, 9 p., 11495.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Morphology and Functional Anatomy

    Møbjerg, Nadja, Jørgensen, Aslak, Kristensen, Reinhardt Møbjerg & Cardoso Neves, R. A., 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 57-94 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  98. Published

    Muscle PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Maag Kristensen, C., Jessen, H., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Acta Physiologica. 224, 4, p. 1-17 e13158.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Na+,HCO3--cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

    Lee, S., Axelsen, T. V., Jesse, N., Pedersen, Stine Helene Falsig, Vahl, P. & Boedtkjer, E., 2018, In: Oncogene. 37, 41, p. 5569-5584

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    P2X receptor-ion channels in the inflammatory response in adipose tissue and pancreas-potential triggers in onset of type 2 diabetes?

    Novak, Ivana & Solini, A., 2018, In: Current Opinion in Immunology. 52, p. 1-7 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  101. Published

    PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Kristensen, C. M., Olsen, M. A., Jessen, H., Brandt, N., Meldgaard, J. N. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 10, p. 1431-1447

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice

    Kristensen, C. M., Dethlefsen, M. M., Tøndering, A. S., Lassen, S. B., Meldgaard, J. N., Ringholm, S. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 15, p. 1-15 e13819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Phylogeny and Integrative Taxonomy of Tardigrada

    Jørgensen, Aslak, Kristensen, Reinhardt Møbjerg & Møbjerg, Nadja, 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 95-114 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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