Cell Biology and Physiology

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  1. 2016
  2. Published

    The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish

    Berchtold, Martin Werner, Zacharias, T., Kulej, K., Wang, K., Torggler, R., Jespersen, Thomas, Chen, J. N., Larsen, M. R. & la Cour, J. M., 2016, In: Journal of Biological Chemistry. 291, 52, p. 26636-26646 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules

    Halberg, Kenneth Veland, Rainey, S. M., Veland, I. R., Neuert, H., Dornan, A. J., Klämbt, C., Davies, S. & Dow, J. A. T., 2016, In: Nature Communications. 7, 10 p., 11266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2

    Hendus-Altenburger, R., Pedraz Cuesta, E., Olesen, C. W., Papaleo, E., Schnell, J. A., Hopper, J. T. S., Robinson, C. V., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2016, In: BMC Biology. 14, 17 p., 31.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The intraflagellar transport machinery in ciliary signaling

    Mourão, A., Christensen, Søren Tvorup & Lorentzen, E., 2016, In: Current Opinion in Structural Biology. 41, p. 98-108 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    The volume activated potassium channel KCNK5 is up-regulated in activated human T Cells, but volume regulation is impaired

    Kirkegaard, S. S., Strøm, P. D., Gammeltoft, S., Hansen, A. J. & Hoffmann, E. K., 2016, In: Cellular Physiology and Biochemistry. 38, 3, p. 883-892 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Tun formation is not a prerequisite for desiccation tolerance in the marine tidal tardigrade Echiniscoides sigismundi

    Hygum, T. L., Clausen, L. K. B., Halberg, Kenneth Veland, Jørgensen, Aslak & Møbjerg, Nadja, 2016, In: Linnean Society. Zoological Journal. 178, 4, p. 907-911 5 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  8. Published

    Volume regulation in epithelia

    Larsen, Erik Hviid & Hoffmann, E. K., 2016, Ion channels and transporters of epithelia in health and disease. Hamiltion, K. L. & Devor, D. C. (eds.). Springer, Vol. Part 1. p. 131-185 55 p. (Physiology in Health and Disease).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  9. Published

    pH-Regulatory Proteins as Potential Targets in Breast Cancer

    Andersen, Anne Poder, 2016, Department of Biology, Faculty of Science, University of Copenhagen. 187 p.

    Research output: Book/Report › Ph.D. thesis › Research

  10. 2015
  11. Published

    The in vitro blood-brain barrier model under OGD condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  12. Published

    Skeletal muscle to pancreatic β-cell cross-talk: the effect of humoral mediators liberated by muscle contraction and acute exercise on β-cell apoptosis

    Christensen, C. S., P. Christensen, D., Lundh, M., Dahllöf, M. S., Haase, T. N., Velasquez, J. M., Laye, M. J., Mandrup-Poulsen, Thomas & Solomon, T. P. J., Oct 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. E1289-E1298 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Changes in barrier properties and protein expression levels of bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 27 Aug 2015.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  14. Published

    Changes in protein expression levels, Claudin-5 localization and barrier function in bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 4 Jul 2015.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  15. Published

    Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis

    Sales, K. U., Friis, S., Konkel, J. E., Godiksen, S., Hatakeyama, M., Hansen, K. K., Rogatto, S. R., Szabo, R., Vogel, Lotte, Chen, W., Gutkind, J. S. & Bugge, T. H., 15 Jan 2015, In: Oncogene. 34, 3, p. 346-356 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    In vitro characterization of a novel C,N-cyclometalated benzimidazole Ru(II) complex: stability, intracellular distribution and binding, effects on organic osmolyte homeostasis and induction of apoptosis

    Dam, C. S., Henarejos, S. A. P., Tsolakou, T., Segato, C. A., Gammelgaard, Bente, Yellol, G. S., Ruiz, J., Lambert, Ian Henry & Stürup, Stefan, 2015, In: Metallomics. 5, p. 885-895 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

    Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)

    Sauter, D. R. P., Novak, Ivana, Pedersen, Stine Helene Falsig, Larsen, Erik Hviid & Hoffmann, E. K., 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1495-1508 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle

    Edge, J., Muendel, T., Pilegaard, Henriette, Hawke, E., Leikis, M., Lopez-Villalobos, N., Oliveira, R. S. F. & Bishop, D. J., 2015, In: P L o S One. 10, 12, 14 p., e0141317.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Antifungal properties of peptidomimetics with an arginine-[β-(2,5,7-tri-tert-butylindol-3-yl)alanine]-arginine motif against Saccharomyces cerevisiae and Zygosaccharomyces bailii

    Larsen, C. E., Larsen, C. J., Franzyk, Henrik & Regenberg, Birgitte, 2015, In: F E M S Yeast Research. 15, 3, 8 p., fov011.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    CSPP-L and EB3 localize to centriolar satellites and are required for satellite-dependent recruitment of ciliopathy proteins to the centrosome

    Sternemalm, J., Geimer, S., Aarnes, E. K., Frikstad, K. M., Stokke, T., Pedersen, Lotte Bang & Patzke, S., 2015, In: Cilia. 4, Suppl. 1, 1 p., P76.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells

    Nygaard, M. B., Almstrup, Kristian, Lindbæk, L., Christensen, Søren Tvorup & Svingen, T., 2015, In: Scientific Reports. 5, 14 p., 10364 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor

    Schultz, H. S., Nitze, L. M., Zeuthen, L. H., Keller, P., Gruhler, A., Pass, J., Chen, J., Guo, L., Fleetwood, A. J., Hamilton, J. A., Berchtold, Martin Werner & Panina, S., 2015, In: Journal of Immunology. 194, 7, p. 3169-3179 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

    Sigurðsson, H. H., Olesen, C. W., Dybboe, R., Lauritzen, G. & Pedersen, Stine Helene Falsig, 2015, In: Molecular Cancer Research. 13, 1, p. 63-77 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Coordination of TGFβ/BMP signaling is associated with the primary cilium

    Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  26. Published

    Evolutionary implications of localization of the signaling scaffold protein Parafusin to both cilia and the nucleus

    Satir, B. H., Wyroba, E., Liu, L., Lethan, M., Satir, P. & Christensen, Søren Tvorup, 2015, In: Cell Biology International. 39, 2, p. 136-145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Expression of the oncogenic, constitutive active Platelet-Derived Growth Factor Receptor alpha D842V mutant induces loss of primary cilia

    Nielsen, B. S., Schmid, F., Malinda, R., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., P63.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  28. Published

    Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling

    Basse, A. L., Dixen, K., Yadav, R., Tygesen, M. P., Qvortrup, Klaus, Kristiansen, Karsten, Quistorff, B., Gupta, R., Wang, J. & Hansen, Jacob B., 2015, In: BMC Genomics. 16, 19 p., 215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Ins and outs of GPCR signaling in primary cilia

    Schou, K. B., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2015, In: E M B O Reports. 16, 9, p. 1099-1113 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Integrin β1, osmosensing, and chemoresistance in mouse ehrlich carcinoma cells

    Sørensen, B. H., Rasmussen, L. J. H., Broberg, B. S., Klausen, T. K., Sauter, D. R. P., Lambert, Ian Henry, Aspberg, A. & Hoffmann, E. K., 2015, In: Cellular Physiology and Biochemistry. 36, 1, p. 111-132 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

    Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Kinesin-3 motor protein KIF13B localizes to centrosomes and primary cilia and regulates ciliary length and signaling

    Schou, K. B., Mogensen, J. B., Aleliunaite, A., Morthorst, Stine Kjær, Veland, I., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Cilia. 4, Suppl. 1, 1 p., O3.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  33. Published

    Mechanisms Regulating Acid-Base Transporter Expression in Breast- and Pancreatic Cancer: Contributions to the Cancer Phenotype

    Gorbatenko, A., 2015, Department of Biology, Faculty of Science, University of Copenhagen. 180 p.

    Research output: Book/Report › Ph.D. thesis › Research

  34. Published

    Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells

    Rasmussen, L. J. H., Mûller, H. S. H., Jørgensen, B., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2015, In: American Journal of Physiology: Cell Physiology. 308, 2, p. C101-C110 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Physiological role of taurine - from organism to organelle

    Lambert, Ian Henry, Kristensen, D. M. B., Holm, J. B. & Mortensen, Ole Hartvig, 2015, In: Acta Physiologica (Print). 213, 1, p. 191-212 22 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

    Nadeem, A., Sanborn, J., Gettel, D. L., Ho C.S., J., Rydström, A., Ngassam, V. N., Klausen, T. K., Pedersen, Stine Helene Falsig, Lam, M., Parikh, A. N. & Svanborg, C., 2015, In: Scientific Reports. 5, 14 p., 16432.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Regulation of p53 in NIH3T3 mouse fibroblasts following hyperosmotic stress

    Lambert, Ian Henry, Enghoff, M. S., Brandi, M. & Hoffmann, E. K., 2015, In: Physiological Reports. 3, 6, 9 p., e12412.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance

    Hoffmann, E. K., Sørensen, B. H., Sauter, D. R. P. & Lambert, Ian Henry, 2015, In: Channels (Austin). 9, 6, p. 380-396 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Skeletal muscle interleukin-6 regulates metabolic factors in iWAT during HFD and exercise training

    Knudsen, Jakob Grunnet, Bertholdt, L., Joensen, E., Lassen, S. B., Hidalgo, J. & Pilegaard, Henriette, 2015, In: Obesity. 23, 8, p. 1616-1624 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells

    Giannuzzo, A., Pedersen, Stine Helene Falsig & Novak, Ivana, 2015, In: Molecular Cancer. 14, 15 p., 203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The identification of a volume-regulated anion channel: an amazing Odyssey

    Pedersen, Stine Helene Falsig, Klausen, T. K. & Nilius, B., 2015, In: Acta Physiologica (Print). 213, 4, p. 868-881 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

    Benmerah, A., Durand, B., Giles, R. H., Harris, T., Kohl, L., Laclef, C., Meilhac, S. M., Mitchison, H. M., Pedersen, Lotte Bang, Roepman, R., Swoboda, P., Ueffing, M. & Bastin, P., 2015, In: Cilia. 4, 5, 14 p.

    Research output: Contribution to journal › Conference article › Research

  45. Published

    The retinoblastoma protein: multitasking to suppress tumorigenesis

    Vormer, T. L., Hansen, Jacob B. & Riele, H. T., 2015, In: Molecular & Cellular Oncology. 2, 1, 2 p., e968062-1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Vasopressin regulation of sodium transport in the distal nephron and collecting duct

    Kortenoeven, M. L. A., Pedersen, N. B., Rosenbæk, L. L. & Fenton, R. A., 2015, In: American Journal of Physiology: Renal Physiology. 309, 4, p. F280-F299 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2014
  48. Published

    B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with Dasatinib in cutaneous T-cell lymphoma (CTCL)

    Petersen, D. L., Krejsgaard, T., Berthelsen, J., Fredholm, S., Willerslev-Olsen, A., Sibbesen, N. A., Bonefeld, Charlotte Menne, Andersen, M. H., Francavilla, C., Olsen, Jesper Velgaard, Hu, T., Zhang, M., Wasik, M. A., Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 12 Jun 2014, In: Leukemia. 28, p. 2109-12 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF)

    Willerslev-Olsen, A., Litvinov, I. V., Fredholm, S. M., Petersen, D. L., Sibbesen, N. A., Gniadecki, R., Zhang, Q., Bonefeld, Charlotte Menne, Wasik, M. A., Geisler, Carsten, Zhou, Y., Woetmann, Anders , Sasseville, D., Krejsgaard, T. & Ødum, Niels, 15 Apr 2014, In: Cell Cycle. 13, 8, p. 1306-12 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    A divergent calponin homology (NN–CH) domain defines a novel family: implications for evolution of ciliary IFT complex B proteins

    Schou, K. B., Andersen, J. S. & Pedersen, Lotte Bang, 2014, In: Bioinformatics. 30, 7, p. 899-902 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  51. Published

    ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis

    Goggolidou, P., L. Stevens, J., Agueci, F., Keynton, J., Wheway, G., T. Grimes, D., H. Patel, S., Hilton, H., Morthorst, S. K., DiPaolo, A., J. Williams, D., Sanderson, J., V. Khoronenkova, S., Powles-Glover, N., Ermakov, A., T. Esapa, C., Romero, R., L. Dianov, G., Briscoe, J., A. Johnson, C. & 2 others, Pedersen, Lotte Bang & P. Norris, D., 2014, In: Development. 141, p. 3966-3977 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential

    Kong, S. C., Giannuzzo, A., Novak, Ivana & Pedersen, Stine Helene Falsig, 2014, In: Biochemistry and Cell Biology. 92, 6, p. 449-459 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  53. Published

    Acquired cisplatin resistance in human ovarian A2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate

    Sørensen, B. H., Thorsteinsdottir, U. A. & Lambert, Ian Henry, 2014, In: American Journal of Physiology: Cell Physiology. 307, 12, p. C1071-C1080 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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