Cell Biology and Physiology

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  1. 2019
  2. Published

    Proteins with calmodulin-like domains: structures and functional roles

    Villalobo, A., González-Muñoz, M. & Berchtold, Martin Werner, 2019, In: Cellular and Molecular Life Sciences. 76, 12, p. 2299-2328

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Regulation and structural aspects of the human Na+/H+ exchanger NHE1: Roles of the N-terminal region and interactions with lipids

    Vogensen, J., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  4. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

    Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses

    Zou, Y., Xue, W., Luo, G., Deng, Z., Qin, P., Guo, R., Sun, H., Xia, Y., Liang, S., Dai, Y., Wan, D., Jiang, R., Su, L., Feng, Q., Jie, Z., Guo, T., Xia, Z., Liu, C., Yu, J., Lin, Y. & 11 others, Tang, S., Huo, G., Xu, X., Hou, Y., Liu, X., Wang, J., Yang, H., Kristiansen, Karsten, Li, J., Jia, H. & Xiao, L., 2019, In: Nature Biotechnology. 37, 2, p. 179-185

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors

    Ísberg, Ó. G., Kim, Jiyoung, Fridriksdottir, A. J., Morsing, M., Timmermans-Wielenga, V., Rønnov-Jessen, Lone, Petersen, Ole William & Villadsen, René, 2019, In: Scientific Reports. 9, 11 p., 14843.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2018
  9. Published

    The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

    Andersen, Anne Poder, Samsøe-Petersen, Jacob, Ørnbo, E. K., Bødtkjer, E., Moreira, José, Kveiborg, Marie & Pedersen, Stine Helene Falsig, 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Stress-induced modulation of volume-regulated anions channels in human alveolar carcinoma cells

    Bach, M. D., Sørensen, B. H. & Lambert, Ian Henry, 2018, In: Physiological Reports. 6, 19, p. 1-22 e13869.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

    Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  12. Published

    Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting

    Bertholdt, L., Gudiksen, Anders, Jessen, H. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1597-1613

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans

    Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Villesen, I., Tybirk, J., van Hall, Gerrit, Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Journal of Applied Physiology. 124, 3, p. 729-740 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Bangsbo, Jens & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 7, 12 p., e13651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle

    Brandt, N., Nielsen, L., Buch, B. T., Gudiksen, Anders, Jørgensen, Stine Ringholm, Hellsten, Ylva, Bangsbo, Jens & Pilegaard, Henriette, 1 Jan 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E1-E20 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Metformin targets brown adipose tissue in vivo and reduces oxygen consumption in vitro

    Breining, P., Jensen, J. B., Sundelin, E. I., Gormsen, L. C., Jakobsen, S., Busk, M., Rolighed, L., Bross, P., Fernandez-Guerra, P., Markussen, L. K., Rasmussen, N. E., Hansen, Jacob B., Pedersen, S. B., Richelsen, B. & Jessen, N., 2018, In: Diabetes, Obesity and Metabolism. 20, 9, p. 2264-2273

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Deconstructing the principles of ductal network formation in the pancreas

    Dahl-Jensen, Svend Bertel, Yennek, S., Flasse, L., Larsen, Hjalte List, Sever, D., Karremore, G., Novak, Ivana, Sneppen, Kim & Botton, A., 2018, In: PLOS Biology. 16, 7, 25 p., e2002842.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Impact of liver PGC-1α on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF

    Dethlefsen, M. M., Kristensen, C. M., Tondering, A. S., Lassen, S. B., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 13, p. 1-16 e13731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

    Dethlefsen, M. M., Halling, Jens Frey, Møller, H. D., Plomgaard, Peter Stendahl, Regenberg, Birgitte, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Experimental Gerontology. 111, p. 141-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Metabolic stress-dependent regulation of the mitochondrial biogenic molecular response to high-intensity exercise in human skeletal muscle

    Fiorenza, Matteo, Gunnarsson, T. P., Hostrup, Morten, Iaia, F. M., Schena, F., Pilegaard, Henriette & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 14, p. 2823-2840 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Roles of pH in control of cell proliferation

    Flinck, M., Kramer, S. H. & Pedersen, Stine Helene Falsig, 2018, In: Acta Physiologica. 223, 3, p. 1-17 e13068.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells

    Flinck, M., Kramer, S. H., Schnipper, J., Andersen, Anne Poder & Pedersen, Stine Helene Falsig, 2018, In: Cell Cycle. 17, 9, p. 1056-1067

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Human adipose glycerol flux is regulated by a pH gate in AQP10

    Gotfryd, K., Mósca, A. F., Missel, Julie Winkel, Truelsen, S. F., Wang, Kaituo, Spulber, M., Krabbe, S., Hélix-nielsen, C., Laforenza, U., Soveral, G., Pedersen, Per Amstrup & Gourdon, Pontus Emanuel, 2018, In: Nature Communications. 9, p. 1-11 4749.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Training state and fasting-induced PDH regulation in human skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Villesen, I., Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1633-1645 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Environmental Adaptations: Encystment and Cyclomorphosis

    Guidetti, R. & Møbjerg, Nadja, 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 249-271 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  28. Published

    Beta2-adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men

    Hostrup, Morten, Reitelseder, S., Jessen, Søren Kaare, Kalsen, A., Nyberg, M. P., Egelund, J., Kreiberg, M., Maag Kristensen, C., Thomassen, Martin, Pilegaard, Henriette, Backer, Vibeke, Jacobson, G. A., Holm, L. & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 17, p. 4121-4139 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2

    Højfeldt, J. W., Laugesen, A., Willumsen, Berthe Marie, Damhofer, H., Hedehus, L., Tvardovskiy, A., Mohammad, F., Jensen, O. N. & Helin, K., 2018, In: Nature Structural & Molecular Biology. 25, p. 225-232 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Phylogeny and Integrative Taxonomy of Tardigrada

    Jørgensen, Aslak, Kristensen, Reinhardt Møbjerg & Møbjerg, Nadja, 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 95-114 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  31. Published

    Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers

    Kjeld, T., Stride, N., Gudiksen, Anders, Hansen, E. G., Arendrup, H. C., Horstmann, P. F., Zerahn, B., Jensen, Lars Thorbjørn, Nordsborg, Nikolai Baastrup, Bejder, Jacob & Halling, Jens Frey, 19 Sep 2018, In: P L o S One. 13, 9, p. 1-13 13 p., e0201401.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

    Klærke, Dan Arne, Tejada, M. D. L. A., Christensen, V. G., Lassen, M., Pedersen, Per Amstrup & Callø, Kirstine, 2018, In: Current Protocols in Pharmacology. 81, 1, p. e37 17 p., e37.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Skeletal Muscle Interleukin-6 Regulates Hepatic Cytochrome P450 Expression: Effects of 16-Week High-Fat Diet and Exercise

    Knudsen, Jakob Grunnet, Bertholdt, L., Gudiksen, Anders, Gerbal-Chaloin, S. & Rasmussen, M. K., 2018, In: Toxicological Sciences. 162, 1, p. 309-317 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Prior exercise training improves cold tolerance independent of indices associated with non-shivering thermogenesis

    Knuth, C. M., Peppler, W. T., Townsend, L. K., Miotto, P. M., Gudiksen, Anders & Wright, D. C., 2018, In: The Journal of Physiology. 596, 18, p. 4375-4391

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Kristensen, C. M., Olsen, M. A., Jessen, H., Brandt, N., Meldgaard, J. N. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 10, p. 1431-1447

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice

    Kristensen, C. M., Dethlefsen, M. M., Tøndering, A. S., Lassen, S. B., Meldgaard, J. N., Ringholm, S. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 15, p. 1-15 e13819.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Facilitating the Cellular Accumulation of Pt-Based Chemotherapeutic Drugs

    Lambert, Ian Henry & Sørensen, B. H., 1 Aug 2018, In: International Journal of Molecular Sciences . 19, 8, p. 1-19 2249.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Na+,HCO3--cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

    Lee, S., Axelsen, T. V., Jesse, N., Pedersen, Stine Helene Falsig, Vahl, P. & Boedtkjer, E., 2018, In: Oncogene. 37, 41, p. 5569-5584

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Muscle PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Maag Kristensen, C., Jessen, H., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Acta Physiologica. 224, 4, p. 1-17 e13158.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    GSK3 is a negative regulator of the thermogenic program in brown adipocytes

    Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

    Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2018, In: F E B S Journal. 285, 24, p. 4535-4564

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Regulation of vesicle trafficking at the primary cilium

    Morthorst, Stine Kjær, 2018, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  44. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Morphology and Functional Anatomy

    Møbjerg, Nadja, Jørgensen, Aslak, Kristensen, Reinhardt Møbjerg & Cardoso Neves, R. A., 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 57-94 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  46. Published

    CRISPR-C: circularization of genes and chromosome by CRISPR in human cells

    Møller, H. D., Lin, L., Xiang, X., Petersen, T. S., Huang, J., Yang, L., Kjeldsen, E., Jensen, U. B., Zhang, X., Liu, X., Xu, X., Wang, J., Yang, H., Church, G. M., Bolund, L., Regenberg, Birgitte & Luo, Y., 2018, In: Nucleic Acids Research. 46, 22, p. 1-13 e131.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

    Møller, H. D., Mohiyuddin, M., Prada Luengo, Inigo, Sailani, M. R., Halling, Jens Frey, Plomgaard, Peter Stendahl, Maretty, L., Hansen, Anders Johannes, Snyder, M. P., Pilegaard, Henriette, Lam, H. Y. K. & Regenberg, Birgitte, 1 Dec 2018, In: Nature Communications. 9, 12 p., 1069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    P2X receptor-ion channels in the inflammatory response in adipose tissue and pancreas-potential triggers in onset of type 2 diabetes?

    Novak, Ivana & Solini, A., 2018, In: Current Opinion in Immunology. 52, p. 1-7 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Trafficking, localization and degradation of the Na+,HCO3- Co-transporter NBCn1 in kidney and breast epithelial cells

    Olesen, C. W., Vogensen, J., Axholm, I., Severin, M., Schnipper, J., Pedersen, I. S., von Stemann, J. H., Schrøder, J. M., Christensen, D. P. & Pedersen, Stine Helene Falsig, 2018, In: Scientific Reports. 8, p. 1-16 7435.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    From channel proteins to industrial biomimetic membrane technology

    Pedersen, Per Amstrup, Bjørkskov, F. B., Alvisse, S. & Hélix-Nielsen, C., 2018, In: Faraday Discussions. 209, p. 287-301 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

    Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice

    Rasmussen, M. K., Bertholdt, L., Gudiksen, Anders, Pilegaard, Henriette & Knudsen, Jakob Grunnet, 2018, In: Toxicology Letters. 282, p. 93-99 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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