Cell Biology and Physiology

  1. 2018
  2. Published

    Development and validation of an ICP-MS method for quantification of total carbon and platinum in cell samples and comparison of open-vessel and microwave-assisted acid digestion methods

    Riisom, M., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 158, p. 144-150 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Human AQP5 facilitates hydrogen peroxide permeation and improves cell resistance to oxidative stress

    Rodrigues, C., Mósca, A. F., Lopes, D., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2018, In: Free Radical Biology and Medicine. 120, Suppl. 1, p. S70 P-86.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  4. Published

    TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms

    Rosengren, T., Larsen, L. J., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Møller, L. B., 2018, In: Cellular and Molecular Life Sciences. 75, 14, p. 2663-2680 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine

    Rubino, S., Bach, M. D., Schober, A. L., Lambert, Ian Henry & Mongin, A. A., 2018, In: Frontiers in Oncology. 8, 12 p., 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Genetic Analysis of Signal Generation by the Rgt2 Glucose Sensor of Saccharomyces cerevisiae

    Scharff-Poulsen, P., Moriya, H. & Johnston, M., 1 Aug 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 8, p. 2685-2696 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

    Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, Lars Allan, Andersen, J. S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2018, In: Journal of Cell Biology. 217, 1, p. 151-161 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(II) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis

    Sørensen, B. H., Werth, P., Lambert, Ian Henry & Bednarski, P. J., 2018, In: Metallomics. 10, 2, p. 323-336 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Characterization of Taurine Transporting Systems During Acquirement of Resistance to Platinum(II)-based, Chemotherapeutic Drugs

    Sørensen, B. H., 2018, Department of Biology, Faculty of Science, University of Copenhagen. 190 p.

    Research output: Book/ReportPh.D. thesisResearch

  10. Published

    Modelling extreme desiccation tolerance in a marine tardigrade

    Sørensen-Hygum, T. L., Stuart, R. M., Jørgensen, Aslak & Møbjerg, Nadja, 2018, In: Scientific Reports. 8, 9 p., 11495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The P2X7 receptor and pannexin-1 are involved in glucose-induced autocrine regulation in β-cells

    Tozzi, M., Larsen, A. T., Lange, S. C., Giannuzzo, A., Andersen, M. N. & Novak, Ivana, 2018, In: Scientific Reports. 8, 15 p., 8926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Calmodulin as a protein linker and a regulator of adaptor/scaffold proteins

    Villalobo, A., Ishida, H., Vogel, H. J. & Berchtold, Martin Werner, 2018, In: B B A - Molecular Cell Research. 1865, 3, p. 507-521 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

    Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment

    la Cour, J. M., Gojkovic, P. W., Ambjorner, S. E. B., Bagge, J., Jensen, S. M., Panina, S. & Berchtold, Martin Werner, 2018, In: PLOS ONE. 13, 9, p. 1-13 e0204520.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2017
  16. Published

    Mutation of the planar cell polarity gene VANGL1 in adolescent idiopathic scoliosis

    Andersen, M. R., Farooq, M., Rasmussen, K. K., Kjaer, K. W., Simony, A., Christensen, Søren Tvorup & Larsen, Lars Allan, 2017, In: Spine. 42, 12, p. E702–E707 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer

    Baldini, N., de Milito, A., Feron, O., Gillies, R. J., Michiels, C., Otto, A. M., Pastoreková, S., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Supuran, C. T. & Avnet, S., 4 Jul 2017, In: Frontiers in Pharmacology. 8, 5 p., 411.

    Research output: Contribution to journalComment/debateResearch

  18. Published

    Regulation of glycolysis in brown adipocytes by HIF-1α

    Basse, A. L., Isidor, Marie Sophie, Winther, Sally, Skjoldborg, N. B., Murholm, M., Andersen, E. S., Pedersen, S. B., Wolfrum, C., Quistorff, B. & Hansen, Jacob B., 22 Jun 2017, In: Scientific Reports. 7, 15 p., 4052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Mechanisms Underlying Profibrotic Epithelial Phenotype and Epithelial-Mesenchymal Crosstalk

    Bialik, J. F., 2017, Department of Biology, Faculty of Science, University of Copenhagen. 182 p.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published

    Persistence and drug tolerance in pathogenic yeast

    Bojsen, R. K., Regenberg, Birgitte & Folkesson, A., Feb 2017, In: Current Genetics. 63, 1, p. 19-22 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle

    Brandt, N., Dethlefsen, M. M., Bangsbo, Jens & Pilegaard, Henriette, 2017, In: P L o S One. 12, 10, 21 p., e0185993.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) and transforming growth factor β (TGF-β) signaling

    Christensen, Søren Tvorup, Morthorst, Stine Kjær, Mogensen, J. B. & Pedersen, Lotte Bang, 2017, In: Cold Spring Harbor Perspectives in Biology. 9, 6, 18 p., a028167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A safflower oil based high-fat/high-sucrose diet modulates the gut microbiota and liver phospholipid profiles associated with early glucose intolerance in the absence of tissue inflammation

    Danneskiold-Samsøe, Niels Banhos, Andersen, D., Radulescu, I. D., Hansen, Ann Normann, Brejnrod, A. D., Kragh, M., Madsen, T., Nielsen, C., Josefsen, K. E., Fretté, X., Fjære, E., Madsen, L., Hellgren, L. I., Brix, S. & Kristiansen, Karsten, May 2017, In: Molecular Nutrition & Food Research. 61, 5, 11 p., 1600528.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype

    Flachs, P., Adamcova, K., Zouhar, P., Marques, C., Janovska, P., Viegas, I., Jones, J. G., Bardova, K., Svobodova, M., Hansikova, J., Kuda, O., Rossmeisl, M., Aune, U. L., Borkowska, A. G., Kristiansen, Karsten, Madsen, L. & Kopecky, J., Mar 2017, In: International Journal of Obesity. 41, 3, p. 372-380 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Normal and malignant cells exhibit differential responses to calcium electroporation

    Frandsen, S. K., Krüger, M. B., Mangalanathan, U. M., Tramm, T., Mahmood, F., Novak, Ivana & Gehl, Julie, Aug 2017, In: Cancer Research. 77, 16, p. 4389-4401 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Proof of region-specific multipotent progenitors in human breast epithelia

    Fridriksdottir, A. J., Villadsen, René, Morsing, M., Klitgaard, M. C., Kim, Jiyoung, Petersen, Ole William & Rønnov-Jessen, Lone, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. E10102–E10111

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effects of training status on PDH regulation in human skeletal muscle during exercise

    Gudiksen, Anders, Bertholdt, L., Stankiewicz, T., Tybirk, J., Plomgaard, Peter Stendahl, Bangsbo, Jens & Pilegaard, Henriette, 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 12, p. 1615-1630 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders, Bertholdt, L., Vingborg, M. B., Hansen, H. W., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E204-E214 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle

    Gudiksen, Anders & Pilegaard, Henriette, 10 Apr 2017, In: Physiological Reports. 5, 7, 15 p., e13222.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Autophagy-dependent beneficial effects of exercise

    Halling, Jens Frey & Pilegaard, Henriette, Aug 2017, In: Cold Spring Harbor Perspectives in Medicine. 7, 8, a029777.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1)

    Hendus-Altenburger, R., Lambrughi, M., Terkelsen, Thilde Bagger, Pedersen, Stine Helene Falsig, Papaleo, E., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Sep 2017, In: Cellular Signalling. 37, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

    Hopkinson, B. M., Klitgaard, M. C., Petersen, Ole William, Villadsen, René, Rønnov-Jessen, Lone & Kim, Jiyoung, 7 Feb 2017, In: OncoTarget. 8, 6, p. 10580-10593 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Sliding doors: heteromeric, volume-sensitive osmolyte channels

    Lambert, Ian Henry, 15 Nov 2017, In: The Journal of Physiology. 595, 22, p. 6807-6807 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  34. Published

    Hot spots of N2O emission move with the seasonally mobile oxic-anoxic interface in drained organic soils

    Lee, A. J., Winther, M. N., Priemé, Anders, Blunier, Thomas & Christensen, Søren Tvorup, 1 Dec 2017, In: Soil Biology & Biochemistry. 115, p. 178-186 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Implications of the Primary Cilium in Cellular Signaling and Brain Development

    Lindbæk, L., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  36. Published

    Opposite regulation of insulin sensitivity by dietary lipid versus carbohydrate excess

    Lundsgaard, Anne-Marie, Sjøberg, K. A., Høeg, L. D., Jeppesen, J., Jordy, A. B., Serup, A. K. L., Fritzen, Andreas Mæchel, Pilegaard, Henriette, Myrmel, L. S., Madsen, L., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2017, In: Diabetes. 66, 10, p. 2583-2595 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Patient-specific three-dimensional explant spheroids derived from human nasal airway epithelium: a simple methodological approach for ex vivo studies of primary ciliary dyskinesia

    Marthin, J. K., Stevens, E. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Nielsen, Kim G., 23 Mar 2017, In: Cilia. 6, 9 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism

    Miranda, M. Z., Bialik, J. F., Speight, P., Dan, Q., Yeung, T., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2017, In: Journal of Biological Chemistry. 292, 36, p. 14902-14920 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer

    Pedersen, A., Mendes Lopes de Melo, J., Mørup, N., Tritsaris, Katerina & Pedersen, Stine Helene Falsig, 2017, In: BMC Cancer. 17, 15 p., 542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Tubulin transport in cilia: how many tubulin cargo-binding sites per IFT particle? (retrospective on DOI 10.1002/bies.201400007)

    Pedersen, Lotte Bang, 2017, In: BioEssays. 39, 1, 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  41. Published

    Alternating pH landscapes shape epithelial cancer initiation and progression: focus on pancreatic cancer

    Pedersen, Stine Helene Falsig, Novak, Ivana, Alves, F., Schwab, A. & Pardo, L. A., Jun 2017, In: BioEssays. 39, 6, 10 p., 1600253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism

    Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, Marie Sophie, Markussen, L. K., Viuff, B. M., Lambert, Ian Henry, Hansen, Jacob B. & Pedersen, Stine Helene Falsig, 12 Oct 2017, In: Scientific Reports. 7, 1, 13 p., 13101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling.

    Schou, K. B., Mogensen, J. B., Morthorst, Stine Kjær, Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 30 Jan 2017, In: Nature Communications. 8, 15 p., 14177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

    Skjørringe, T., Pedersen, Per Amstrup, Thorborg, S. S., Nissen, P., Gourdon, Pontus Emanuel & Møller, L. B., 7 Apr 2017, In: Scientific Reports. 7, 18 p., 757.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression

    Sonne, Si Brask, Yadav, R., Yin, G., Dalgaard, M. D., Myrmel, L. S., Gupta, R., Wang, J., Madsen, L., Kajimura, S. & Kristiansen, Karsten, 2017, In: Adipocyte. 6, 2, p. 124-133 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Roles of pH and the Na+/H+ exchanger NHE1 in cancer: from cell biology and animal models to an emerging translational perspective?

    Stock, C. & Pedersen, Stine Helene Falsig, Apr 2017, In: Seminars in Cancer Biology. 43, p. 5-16 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Ion channels in control of pancreatic stellate cell migration

    Storck, H., Hild, B., Schimmelpfennig, S., Sargin, S., Nielsen, N., Zaccagnino, A., Budde, T., Novak, Ivana, Kalthoff, H. & Schwab, A., 3 Jan 2017, In: OncoTarget. 8, 1, p. 769-784 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Mitigating Cyanide Poisoning

    Suman, S. G., Gretarsdottir, J. M., Lambert, Ian Henry & Stürup, Stefan, Jul 2017, p. S261-S261.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  49. Published

    Single-Channel Recordings of K+ Channels Expressed in Saccharomyces Cerevisiae

    Tejada, M. D. L. A., Molbaek, K., Cazimi, H., Ellekvist, P., Callø, Kirstine, Nielsen, C. H., Pedersen, Per Amstrup & Klærke, Dan Arne, 2017, In: Biophysical Journal. 112, 3, Suppl. 1, p. 406A 1 p., 2002-Pos Board B322.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    Purinergic receptors in adipose tissue as potential targets in metabolic disorders

    Tozzi, M. & Novak, Ivana, 24 Nov 2017, In: Frontiers in Pharmacology. 8, 8 p., 878.

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Human embryonic stem cell derived cardiomyocytes self-arrange with areas of different subtypes during differentiation

    Vestergaard, M. L., Grubb, Søren, Rasmussen, K. K., Anderson-Jenkins, Z. L., Grunnet-Lauridsen, K., Callø, Kirstine, Clausen, C., Christensen, Søren Tvorup, Møllgård, Kjeld & tcg964, tcg964, 1 Nov 2017, In: Stem Cells and Development. 26, 21, p. 1566-1577 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Division of labour in the yeast: Saccharomyces cerevisiae

    Wloch-Salamon, D. M., Fisher, Roberta May & Regenberg, Birgitte, Oct 2017, In: Yeast. 34, 10, p. 399-406 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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