Cell Biology and Physiology

  1. Published

    Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes

    Abraham, E. H., Shrivastav, B., Salikhova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 19 May 2001, In: Blood Cells, Molecules and Diseases. 27, 1, p. 181-200 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain.

    Adari, H., Lowy, D. R., Willumsen, Berthe Marie, Der, C. J. & McCormick, F., 1988, In: Science. 240, 4851, p. 518-21 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Functional analysis of candidate ABC transporter proteins for sitosterol transport

    Albrecht, C., Elliott, J. I., Sardini, A., Litman, Thomas, Stieger, B., Meier, P. J. & Higgins, C. F., 23 Dec 2002, In: BBA General Subjects. 1567, 1-2, p. 133-42 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Calmodulin downregulation in conditional knockout HeLa cells inhibits cell migration

    Alcalde, J., Munk, M., González-Muñoz, M., Panina, S., Berchtold, Martin Werner & Villalobo, A., 2021, In: Archives of Biochemistry and Biophysics. 697, 9 p., 108680.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Spontaneous metastasis in congenic mice with transgenic breast cancer is unaffected by plasminogen gene ablation

    Almholt, K., Juncker-Jensen, A., Lærum, O. D., Johnsen, M., Rømer, J. & Lund, L. R., 2013, In: Clinical and Experimental Metastasis. 30, 3, p. 277-288 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model

    Almholt, K., Juncker-Jensen, A., Lærum, O. D., Danø, K. B., Johnsen, M., Lund, L. R. & Rømer, J., 2008, In: Molecular Cancer Therapeutics. 7, 9, p. 2758-2767 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    From embryonic stem cells to testicular germ cell cancer-- should we be concerned?

    Almstrup, Kristian, Sonne, Si Brask, Hoei-Hansen, C. E., Ottesen, A. M., Nielsen, J. E., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: International Journal of Andrology. 29, 1, p. 211-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Improved gene expression signature of testicular carcinoma in situ

    Almstrup, Kristian, Leffers, H., Lothe, R. A., Skakkebæk, Niels Erik, Sonne, Si Brask, Nielsen, J. E., Rajpert-De Meyts, E. & Skotheim, R. I., 2007, In: International Journal of Andrology. 30, 4, p. 292-303

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ

    Almstrup, Kristian, Ottesen, A. M., Sonne, Si Brask, Hoei-Hansen, C. E., Leffers, H., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2005, In: Cell and Tissue Research. 322, 1, p. 159-65 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling

    Alphonse, N., Wanford, J. J., Voak, A. A., Gay, J., Venkhaya, S., Burroughs, O., Mathew, S., Lee, T., Evans, S. L., Zhao, W., Frowde, K., Alrehaili, A., Dickenson, R. E., Munk, M., Panina, S., Mahmood, I. F., Llorian, M., Stanifer, M. L., Boulant, S., Berchtold, M. W. & 4 others, Bergeron, J. R. C., Wack, A., Lesser, C. F. & Odendall, C., 2022, In: Cell. 185, 13, p. 2354-2369.e17

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs

    Alvarez-Dominguez, J. R., Winther, Sally, Hansen, Jacob B., Lodish, H. F. & Knoll, M., 2022, In: iScience. 25, 1, 25 p., 103680.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange

    Andersen, A., Poulsen, K. A., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: American Journal of Physiology: Cell Physiology. 296, 5, p. C1227-42

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na+/H+ exchanger NHE1

    Andersen, A., Bentzen, Bo Hjorth, Salling, H., Klingberg, H., Kanneworff, M., Grunnet, Morten & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 1, p. 13-24 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    pH-Regulatory Proteins as Potential Targets in Breast Cancer

    Andersen, Anne Poder, 2016, Department of Biology, Faculty of Science, University of Copenhagen. 187 p.

    Research output: Book/ReportPh.D. thesisResearch

  15. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment

    Andersen, Anne Poder, Flinck, M., Oernbo, E. K., Pedersen, N. B., Viuff, B. M. & Pedersen, Stine Helene Falsig, 2016, In: Molecular Cancer. 15, 18 p., 45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms

    Andersen, Anne Poder, Samsøe-Petersen, Jacob, Ørnbo, E. K., Bødtkjer, E., Moreira, José, Kveiborg, Marie & Pedersen, Stine Helene Falsig, 2018, In: International Journal of Cancer. 142, 12, p. 2529-2542 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Metabolic reprogramming by driver mutation-tumor microenvironment interplay in pancreatic cancer: new therapeutic targets

    Andersen, Henriette Berg, Ialchina, Renata, Pedersen, Stine Helene Falsig & Czaplinska, D., 2021, In: Cancer and Metastasis Reviews. 40, 4, p. 1093-1114 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Mutation of the planar cell polarity gene VANGL1 in adolescent idiopathic scoliosis

    Andersen, M. R., Farooq, M., Rasmussen, K. K., Kjaer, K. W., Simony, A., Christensen, Søren Tvorup & Larsen, Lars Allan, 2017, In: Spine. 42, 12, p. E702–E707 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Hjemløse maends psykiske og sociale problemer. En undersøgelse af det københavnske herbergsklientel

    Andersen, P., Knop, J., Almdal, T., Ødum, Niels & Schulsinger, F., 1984, In: Ugeskrift for læger. 146, 14, p. 1074-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells

    Andersen, P., Pedersen, M. W., Woetmann, Anders , Villingshøj, M., Stockhausen, M., Ødum, Niels & Poulsen, H. S., 2008, In: International Journal of Cancer. 122, 2, p. 342-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells

    Andresen, Lars, Hansen, K. A., Jensen, H., Pedersen, Stine Helene Falsig, Stougaard, P., Hansen, H. R., Jurlander, J. & Skov, Søren, 2009, In: Journal of Immunology. 183, 2, p. 897-906 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Cellular signalling by primary cilia in development, organ function and disease

    Anvarian, Zeinab, Mykytyn, K., Mukhopadhyay, S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2019, In: Nature Reviews Nephrology. 15, p. 199-219

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

    Araya-Secchi, R., Bugge, K., Seiffert, P., Petry, A., Haxholm, G. W., Lindorff-Larsen, Kresten, Pedersen, Stine Helene Falsig, Arleth, Lise & Kragelund, Birthe Brandt, 2023, In: eLife. 12, 27 p., e84645.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sodium, Glucose and Dysregulated Glucagon Secretion: The Potential of Sodium Glucose Transporters

    Armour, Sarah Louise, Früh, Alexander Erwin & Knudsen, Jakob Grunnet, 2022, In: Frontiers in Pharmacology. 13, 6 p., 837664.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Metabolic regulation of glucagon secretion

    Armour, Sarah Louise, Stanley, J. E., Cantley, J., Dean, E. D. & Knudsen, Jakob Grunnet, 2023, In: The Journal of endocrinology. 259, 1, 15 p., e230081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells

    Armour, Sarah Louise, Frueh, A., Chibalina, M. V., Dou, H., Argemi Muntadas, Lidia, Hamilton, Alexander, Katzilieris Petras, Georgios, Carmeliet, P., Davies, B., Moritz, Thomas, Eliasson, L., Rorsman, P. & Knudsen, Jakob Grunnet, 2023, In: Diabetes. 72, 10, p. 1446-1459 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Functional characterization of the first missense variant in CEP78, a founder allele associated with cone-rod dystrophy, hearing loss and reduced male fertility

    Ascari, G., Peelman, F., Farinelli, P., Rosseel, T., Lambrechts, N., Wunderlich, K. A., Wagner, M., Nikopoulos, K., Martens, P., Balikova, I., Derycke, L., Holtappels, G., Krysko, O., Van Laethem, T., De Jaegere, S., Guillemyn, B., De Rycke, R., De Bleecker, J., Creytens, D., Van Dorpe, J. & 11 others, Gerris, J., Bachert, C., Neuhofer, C., Walraedt, S., Bischoff, A., Pedersen, Lotte Bang, Klopstock, T., Rivolta, C., Leroy, B. P., De Baere, E. & Coppieters, F., 2020, In: Human Mutation. 41, 5, p. 998-1011 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The different roles of aggrecan interaction domains

    Aspberg, A., 2012, In: Journal of Histochemistry and Cytochemistry. 60, 12, p. 987-996 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Isolation and differentiation of stromal vascular cells to beige/brite cells

    Aune, U. L., Ruiz, L. & Kajimura, S., 2013, In: Journal of Visualized Experiments. 73, e50191.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer

    Avnet, S., Baldini, N., Brisson, L., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Szabadkai, G. & Pastorekova, S., 2019, In: Frontiers in Oncology. 9, 5 p., 1332.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Immunoflourescence and mRNA analysis of human embryonic stem cells (hESCs) grown under feeder-free conditions

    Awan, A., Oliveri, R. S., Jensen, P. L., Christensen, Søren Tvorup & tcg964, tcg964, 1 Jan 2010, In: Methods in Molecular Biology. 584, p. 195-210 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Drug accumulation in the presence of the multidrug resistance pump: dissociation between verapamil accumulation and the action of P-glycoprotein

    Ayesh, S., Litman, Thomas & Stein, W. D., 1997, In: Receptors and Channels. 5, 3-4, p. 175-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo controlled bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown and increased IL-6 release

    Bach, E., Nielsen, R. R., Vendelbo, M., Møller, A. B., Jessen, N., Buhl, M., Hafstrøm, T. K., Holm, L., Pedersen, S. B., Pilegaard, Henriette, Biensøe, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Diabetes. 62, 12, p. 4023-4029

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Stress-induced modulation of volume-regulated anions channels in human alveolar carcinoma cells

    Bach, M. D., Sørensen, B. H. & Lambert, Ian Henry, 2018, In: Physiological Reports. 6, 19, p. 1-22 e13869.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The effect of the Danish Heart Society's blood pressure campaign in 1975 as seen from general practice (Danish)

    Backer, P., Kamper Jorgensen, F., Kragstrup, Jakob & Pedersen, Per Amstrup, 1976, In: Ugeskrift for Laeger. 138, 8, p. 495-499 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    O-glycan initiation directs distinct biological pathways and controls epithelial differentiation

    Bagdonaite, Ieva , Pallesen, E. M. H., Ye, Z., Vakhrushev, Sergey, Marinova, I. N., Nielsen, Mathias Alexander Ingemann, Kramer, S. H., Pedersen, Stine Helene Falsig, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2020, In: EMBO Reports. 21, 6, 17 p., e48885.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Evidence of steady-state fibroblast subtypes in the normal human breast as cells-of-origin for perturbed-state fibroblasts in breast cancer

    Bagger, M. M., Sjölund, J., Kim, Jiyoung, Kohler, Katharina Theresa, Villadsen, René, Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Pietras, K., Rønnov-Jessen, Lone & Petersen, Ole William, 2024, In: Breast Cancer Research. 26, 1, 19 p., 11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

    Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.

    Research output: Contribution to journalComment/debateResearchpeer-review

  40. Published

    15N NMR relaxation studies of calcium-loaded parvalbumin show tight dynamics compared to those of other EF-hand proteins

    Baldellon, C., Alattia, J. R., Strub, M. P., Pauls, T., Berchtold, Martin Werner, Cavé, A. & Padilla, A., 1998, In: Biochemistry. 37, 28, p. 9964-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer

    Baldini, N., de Milito, A., Feron, O., Gillies, R. J., Michiels, C., Otto, A. M., Pastoreková, S., Pedersen, Stine Helene Falsig, Porporato, P. E., Sonveaux, P., Supuran, C. T. & Avnet, S., 4 Jul 2017, In: Frontiers in Pharmacology. 8, 5 p., 411.

    Research output: Contribution to journalComment/debateResearch

  42. Published

    Metabolism and microenvironment in cancer plasticity

    Baldini, N., Sonveaux, P., De Milito, A., Supuran, C. T., Otto, A. M., Stock, C. M., Pedersen, Stine Helene Falsig, Favicchio, R. & Avnet, S., 2016, In: Cancer & Metabolism. 4, Supplement 1, 7 p., 1.

    Research output: Contribution to journalComment/debateResearch

  43. Published

    Regulation of glycolysis in brown adipocytes by HIF-1α

    Basse, A. L., Isidor, Marie Sophie, Winther, Sally, Skjoldborg, N. B., Murholm, M., Andersen, E. S., Pedersen, S. B., Wolfrum, C., Quistorff, B. & Hansen, Jacob B., 22 Jun 2017, In: Scientific Reports. 7, 15 p., 4052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling

    Basse, A. L., Dixen, K., Yadav, R., Tygesen, M. P., Qvortrup, Klaus, Kristiansen, Karsten, Quistorff, B., Gupta, R., Wang, J. & Hansen, Jacob B., 2015, In: BMC Genomics. 16, 19 p., 215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The role of half-transporters in multidrug resistance

    Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, Dec 2001, In: Journal of Bioenergetics and Biomembranes. 33, 6, p. 503-11 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Reply to ‘Paracetamol use in pregnancy — caution over causal inference from available data’; ‘Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy’

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., M. Andrade, A., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 3, p. 192 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  47. Published

    Paracetamol use during pregnancy — a call for precautionary action

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2021, In: Nature Reviews Endocrinology. 17, p. 757–766 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Reply to ‘Paracetamol use in pregnancy — neglecting context promotes misinterpretation’

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 1 p., 386.

    Research output: Contribution to journalLetterResearchpeer-review

  49. Published

    Paracetamol Use During Pregnancy - A Call for Precautionary Action

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2022, In: Obstetrical and Gynecological Survey. 77, 3, p. 133-134 2 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Overproduction of Human Zip (SLC39) Zinc Transporters in Saccharomyces cerevisiae for Biophysical Characterization

    Becares, E. R., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2021, In: Cells. 10, 2, 21 p., 213.

    Research output: Contribution to journalJournal articleResearchpeer-review

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