- 2001
- Published
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)
Robey, R. W., Honjo, Y., van de Laar, A., Miyake, K., Regis, J. T., Litman, Thomas & Bates, S. E., 6 Jun 2001, In: BBA General Subjects. 1512, 2, p. 171-82 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., Jun 2001, In: Cellular and molecular life sciences : CMLS. 58, 7, p. 931-59 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes
Abraham, E. H., Shrivastav, B., Salikhova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 19 May 2001, In: Blood Cells, Molecules and Diseases. 27, 1, p. 181-200 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-function relationships of Na+, K+, ATP, or Mg2+ binding and energy transduction in Na,K-ATPase
Jorgensen, P. L. & Pedersen, Per Amstrup, 1 May 2001, In: Biochimica et Biophysica Acta - Bioenergetics. 1505, 1, p. 57-74 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells
Robey, R. W., Medina-Pérez, W. Y., Nishiyama, K., Lahusen, T., Miyake, K., Litman, Thomas, Senderowicz, A. M., Ross, D. D. & Bates, S. E., Jan 2001, In: Clinical Cancer Research. 7, 1, p. 145-52 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calmodulin protects cells from death under normal growth conditions and mitogenic starvation but plays a mediating role in cell death upon B-cell receptor stimulation
Schmalzigaug, R., Ye, Q. & Berchtold, Martin Werner, 2001, In: Immunology. 103, 3, p. 332-42 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a
Brockdorff, J. L., Gu, H., Mustelin, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 86-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of cytotoxic CD8+CD56+ T cells from human thymocytes by interleukin-15.
Thulesen, S., Nissen, Mogens Holst, Ødum, Niels & Röpke, C., 2001, In: Journal of Interferon & Cytokine Research. 21, 11, p. 905-11 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells
Brender, C., Nielsen, M., Röpke, C., Nissen, M. H., Svejgaard, A., Billestrup, N., Geisler, Carsten & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 80-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.
Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radically altered T cell receptor signaling in glycopeptide-specific T cell hybridoma induced by antigen with minimal differences in the glycan group
Jensen, T., Nielsen, M., Gad, M., Hansen, P., Komba, S., Meldal, M., Ødum, Niels & Werdelin, O., 2001, In: European Journal of Immunology. 31, 11, p. 3197-206 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma
Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.
Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion
Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Bissell, M. J., 2001, In: Breast Cancer Research (Online Edition). 3, p. 213-217Research output: Contribution to journal › Review › Research
- Published
The pump and leak steady-state concept with a variety of regulated leak pathways.
Hoffmann, E. K., 2001, In: Journal of Membrane Biology. 184, 3, p. 321-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Importance of conserved α-subunit segment 709GDGVND for Mg2+ binding, phosphorylation, and energy transduction in Na,K-ATPase
Pedersen, Per Amstrup, Jorgensen, J. R. & Jorgensen, P. L., 1 Dec 2000, In: Journal of Biological Chemistry. 275, 48, p. 37588-37595 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation of multidrug-resistant Ehrlich ascites tumour cells selected in vivo for resistance to etoposide
Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas, Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 353-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone
Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 363-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
Litman, Thomas, Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. & Bates, S. E., Jun 2000, In: Journal of Cell Science. 113 ( Pt 11), p. 2011-21 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane
Rocchi, E., Khodjakov, A., Volk, E. L., Yang, C. H., Litman, Thomas, Bates, S. E. & Schneider, E., 29 Apr 2000, In: Biochemical and Biophysical Research Communications. 271, 1, p. 42-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease
Berchtold, Martin Werner, Brinkmeier, H. & Müntener, M., 2000, In: Physiological Reviews. 80, 3, p. 1215-65 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ceramide-induced TCR up-regulation
Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of cytochalasins on F-actin and morphology of Ehrlich ascites tumor cells.
Mills, J. W., Pedersen, Stine Helene Falsig, Walmod, P. S. & Hoffmann, E. K., 2000, In: Experimental Cell Research. 261, 1, p. 209-19 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise-induced translocation of Na+-K+ pump subunits to the plasma membrane in human skeletal muscle
Juel, C., Nielsen, Jens Jung & Bangsbo, Jens, 2000, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 278, 4, p. R1107-R1110 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells
Skov, S., Bonyhadi, M., Ødum, Niels & Ledbetter, J. A., 2000, In: Journal of Immunology. 164, 7, p. 3500-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interstitial K+ in human skeletal muscle during and after dynamic graded exercise determined by microdialysis
Juel, C., Pilegaard, Henriette, Nielsen, Jens Jung & Bangsbo, Jens, 2000, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 278, 2, p. R400-R406 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter
Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, 4, p. 1137-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients
Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase
Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Kastrup, J., Dietrich, J., Ødum, Niels & Geisler, Carsten, 2000, In: BBA General Subjects. 1497, 3, p. 297-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
Brangi, M., Litman, Thomas, Ciotti, M., Nishiyama, K., Kohlhagen, G., Takimoto, C., Robey, R., Pommier, Y., Fojo, T. & Bates, S. E., 1 Dec 1999, In: Cancer Research. 59, 23, p. 5938-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR
de Bruin, M., Miyake, K., Litman, Thomas, Robey, R. & Bates, S. E., 15 Nov 1999, In: Cancer Letters. 146, 2, p. 117-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cutting edge: Expression of the NF of activated T cells in eosinophils: Regulation by IL-4 and IL-5
Jinquan, T., Quan, S., Jacobi, H. H., Reimert, C. M., Millner, A., Hansen, J. B., Thygesen, C., Ryder, L. P., Madsen, H. O., Malling, H. J. & Poulsen, Lars K., 1 Jul 1999, In: Journal of Immunology. 163, 1, p. 21-24 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833
Robey, R., Bakke, S., Stein, W., Meadows, B., Litman, Thomas, Patil, S., Smith, T., Fojo, T. & Bates, S., 1 Jan 1999, In: Blood. 93, 1, p. 306-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes
Miyake, K., Mickley, L., Litman, Thomas, Zhan, Z., Robey, R., Cristensen, B., Brangi, M., Greenberger, L., Dean, M., Fojo, T. & Bates, S. E., 1 Jan 1999, In: Cancer Research. 59, 1, p. 8-13 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels
Jensen, B. S., Ødum, Niels, Jorgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 19, p. 10917-21 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels
Jensen, B. S., Ødum, Niels, Jørgensen, N. K., Christophersen, P. & Olesen, Søren-Peter, 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, p. 10917-10921Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid tyrosine phosphorylation of Lck following ligation of the tumor-associated cell surface molecule A6H
Labuda, T., Gerwien, J., Ødum, Niels & Dohlsten, M., 1999, In: International Immunology. 11, 3, p. 427-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remodeling of the AB site of rat parvalbumin and oncomodulin into a canonical EF-hand
Cox, J. A., Durussel, I., Scott, D. J. & Berchtold, Martin Werner, 1999, In: European Journal of Biochemistry. 264, 3, p. 790-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CC-chemokine receptor 5 (CCR5) is a marker of, but not essential for the development of human Th1 cells
Ødum, Niels, Bregenholt, S., Eriksen, K. W., Skov, S., Ryder, L. P., Bendtzen, K., Van Neerven, R. J., Svejgaard, A. & Garred, Peter, 1999, In: HLA. 54, 6, p. 572-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Effects of hyperventilation and hypocapnic/normocapnic hypoxemia on renal function and lithium clearance in humans
Christensen, H., Klausen, T., Fogh-Andersen, N., Plum, I., Kanstrup, I. L., Hansen, Jesper Melchior & Olsen, N. V., Dec 1998, In: Anesthesiology. 89, 6, p. 1389-400 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-function relationships of E1-E2 transitions and cation binding in Na,K-pump protein
Jorgensen, P. L., Nielsen, J. M., Rasmussen, J. H. & Pedersen, Per Amstrup, 10 Jun 1998, In: Biochimica et Biophysica Acta - Bioenergetics. 1365, 1-2, p. 65-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma volume in acute hypoxia: comparison of a carbon monoxide rebreathing method and dye dilution with Evans' blue
Poulsen, T. D., Klausen, T., Richalet, J. P., Kanstrup, I. L., Fogh-Andersen, N. & Olsen, N. V., Apr 1998, In: European Journal of Applied Physiology and Occupational Physiology. 77, 5, p. 457-61 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morphology of the Nephron in the mesonephros of Bufo bufo (Amphibia, Anura, Bufonidae)
Møbjerg, Nadja, Larsen, Erik Hviid & Jespersen, Å., 1 Jan 1998, In: Acta Zoologica. 79, 1, p. 31-50 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
15N NMR relaxation studies of calcium-loaded parvalbumin show tight dynamics compared to those of other EF-hand proteins
Baldellon, C., Alattia, J. R., Strub, M. P., Pauls, T., Berchtold, Martin Werner, Cavé, A. & Padilla, A., 1998, In: Biochemistry. 37, 28, p. 9964-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of Stat-3 is involved in the induction of apoptosis after ligation of major histocompatibility complex class I molecules on human Jurkat T cells
Skov, S., Nielsen, M., Bregenholt, S., Ødum, Niels & Claesson, Mogens Helweg, 1998, In: Blood. 91, 10, p. 3566-73 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of dacC, which encodes a new low-molecular-weight penicillin-binding protein in Bacillus subtilis.
Pedersen, Lotte Bang, Murray, T., Popham, D. L. & Setlow, P., 1998, In: Journal of Bacteriology. 180, 18, p. 4967-73 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differentiation and cancer in the mammary gland: shedding light on an old dichotomy
Petersen, Ole William, Rønnov-Jessen, Lone, Weaver, V. M. & Bissell, M. J., 1998, In: Advances in Cancer Research. 75, p. 135-61 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High affinity calmodulin target sequence in the signalling molecule PI 3-kinase
Fischer, R., Julsgart, J. & Berchtold, Martin Werner, 1998, In: FEBS Letters. 425, 1, p. 175-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin 2 and 15 activate Stat3alpha in human T lymphocytes
Nielsen, M., Svendsen, Mette Nordahl, Svejgaard, A. & Ødum, Niels, 1998, In: Cytokine. 10, 10, p. 735-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane
Geisler, Carsten, Dietrich, J., Nielsen, B. L., Kastrup, J., Lauritsen, J. P. H., Ødum, Niels & Bartels, Mette Damkjær, 1998, In: Journal of Biological Chemistry. 273, 33, p. 21316-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer
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Cell volume regulation in epithelial physiology and cancer
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Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells
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GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion
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Acid–base transporters in the context of tumor heterogeneity
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