Cell Biology and Physiology

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  1. 2021
  2. Published

    Paracetamol use during pregnancy — a call for precautionary action

    Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2021, In: Nature Reviews Endocrinology. 17, p. 757–766 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Parathyroid hormone receptor stimulation induces human adipocyte lipolysis and browning

    Breining, P., Pedersen, S. B., Kjolby, M., Hansen, Jacob B., Jessen, N. & Richelsen, B., 2021, In: European Journal of Endocrinology. 184, 5, p. 687-697 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer

    Rolver, M. G. & Pedersen, Stine Helene Falsig, 2021, In: British Journal of Cancer. 124, p. 1-2 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  5. Published

    Recombinant production of membrane proteins in yeast

    Preisler, Sarah Spruce, Hansen, K. M., Nurup, C. N., Beich-Frandsen, M. & Pedersen, Per Amstrup, 2021, Methods in Enzymology. Pyle, A. M. & Christianson, D. W. (eds.). Academic Press, Vol. 660. p. 21-52 32 p. (Methods in Enzymology, Vol. 660).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6. Published

    Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure

    Chen, W., Weng, Z., Xie, Z., Xie, Y., Zhang, C., Chen, Z., Ruan, F., Wang, J., Sun, Y., Fang, Y., Guo, M., Tong, Y., Li, Y. & Tang, C., 2021, In: Epigenetics & Chromatin. 14, 11 p., 40.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Taxonomic Description and Genome Sequence of Christensenella intestinihominis sp. nov., a Novel Cholesterol-Lowering Bacterium Isolated From Human Gut

    Zou, Y., Xue, W., Lin, X., Hu, T., Liu, S., Sun, C., Luo, G., Lv, M., Dai, Y., Kristiansen, Karsten & Xiao, L., 2021, In: Frontiers in Microbiology. 12, 13 p., 632361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The Interplay between Dysregulated Ion Transport and Mitochondrial Architecture as a Dangerous Liaison in Cancer

    Pedersen, Stine Helene Falsig, Flinck, M. & Pardo, L. A., 2021, In: International Journal of Molecular Sciences. 22, 10, 27 p., 5209.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells

    Magni, Lara, Bouazzi, R., Heredero Olmedilla, H., Petersen, P. S. S., Tozzi, M. & Novak, Ivana, 2021, In: Cells. 10, 8, 20 p., 1928.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells

    Doray, A., Lemoine, R., Severin, M., Chadet, S., Lopez-Charcas, O., Héraud, A., Baron, C., Besson, P., Monteil, A., Pedersen, Stine Helene Falsig & Roger, S., 2021, In: Cells. 10, 7, 15 p., 1624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The heart arrhythmia-linked D130G calmodulin mutation causes premature inhibitory autophosphorylation of CaMKII

    Berchtold, Martin Werner, Munk, M., Kulej, K., Porth, I., Lorentzen, Lasse Gøbel, Panina, S., Zacharias, T., Larsen, M. R. & la Cour, J. M., 2021, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1868, 12, 9 p., 119119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

    Sun, C., Wang, H., Ma, Q., Chen, C., Yue, J., Li, B. & Zhang, X., 2021, In: Cell and Bioscience. 11, 12 p., 24.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment

    Fontenete, S., Lerche, Catharina Margrethe, Paasch, U., Perez-Moreno, Mirna, Olesen, U. H. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2020
  15. Published

    The intracellular lipid-binding domain of human Na+/H+ exchanger 1 forms a lipid-protein co-structure essential for activity

    Hendus-Altenburger, R., Vogensen, J., Pedersen, E. S., Luchini, A., Araya-Secchi, R., Bendsoe, A. H., Prasad, N. S., Prestel, Andreas, Cardenas, M., Pedraz-Cuesta, E., Arleth, Lise, Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 3 Dec 2020, In: Communications Biology . 3, 1, 18 p., 731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation

    Fontenete, S., Christensen, J., Martinez-Silgado, A., Zarzuela, E., Muñoz, J., Megias, D., Castellana, D., Loewe, R. & Perez-Moreno, Mirna, 18 Jul 2020, bioRxiv, 58 p. (bioRxiv).

    Research output: Working paper › Preprint › Research

  17. Published

    The γ-hydroxybutyric acid (GHB) analogue NCS-382 is a substrate for both monocarboxylate transporters subtypes 1 and 4

    Thiesen, L., Belew, Zeinu Mussa, Griem-Krey, Nane, Pedersen, Stine Helene Falsig, Crocoll, C., Nour-Eldin, Hussam Hassan & Wellendorph, Petrine, 15 Feb 2020, In: European Journal of Pharmaceutical Sciences. 143, p. 1-9 105203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Ciliary Localization of the Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis

    Stevens, E. M., Vladar, E. K., Alanin, M. C., Christensen, Søren Tvorup, von Buchwald, Christian & Milla, C., Jan 2020, In: American Journal of Respiratory Cell and Molecular Biology. 62, 1, p. 120-123 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Analysis of caveolin in primary cilia

    Morthorst, Stine Kjær, Mogensen, J. B., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2020, Caveolae: Methods and Protocols. Blouin, C. M. (ed.). Humana Press, p. 27-41 (Methods in Molecular Biology, Vol. 2169).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  20. Published

    Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion

    Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Beta-1 and Not Beta-3 Adrenergic Receptors May Be the Primary Regulator of Human Brown Adipocyte Metabolism

    Riis-Vestergaard, M. J., Richelsen, B., Bruun, J. M., Li, W., Hansen, Jacob B. & Pedersen, S. B., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, 12 p., dgz298.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Biophysical characterization and industrial-scale production of Aquaporins: Human aquaporins in relation to lifestyle disease and identification of putative aquaporins for improved water filtration

    Krabbe, S. L., 2020, Department of Biology, Faculty of Science, University of Copenhagen. 216 p.

    Research output: Book/Report › Ph.D. thesis › Research

  23. Published

    Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival

    Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Circle-Seq: Isolation and Sequencing of Chromosome-Derived Circular DNA Elements in Cells

    Møller, H. D., 2020, DNA Electrophoresis: Methods and Protocols. Hanada, K. (ed.). Humana Press, p. 165-181 17 p. (Methods in Molecular Biology, Vol. 2119).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  25. Published

    Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner

    Buch, B. T., Halling, Jens Frey, Jørgensen, Stine Ringholm, Gudiksen, Anders, Kjøbsted, Rasmus, Olsen, M. A., Wojtaszewski, Jørgen F P & Pilegaard, Henriette, 2020, In: F A S E B Journal. 34, 6, p. 8653-8670

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends

    Serra-Marques, A., Martin, M., Katrukha, E. A., Grigoriev, I., Peeters, C. A. E., Liu, Q., Hooikaas, P. J., Yao, Y., Solianova, V., Smal, I., Pedersen, Lotte Bang, Meijering, E., Kaitein, L. C. & Akhmanova, A., 2020, In: eLife. 9, 37 p., e61302.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Description, redescription and revision of sixteen putatively closely related species of Echinoderes (Kinorhyncha: Cyclorhagida), with the proposition of a new species group - the Echinoderes dujardinii group

    Sørensen, Martin Vinther, Goetz, F. E., Herranz, Maria, Chang, C. Y., Chatterjee, T., Durucan, F., Neves, R. C., Yildiz, N. Ö., Norenburg, J. & Yamasaki, H., 2020, In: European Journal of Taxonomy. 730, p. 1-101 101 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Exercise: from physiology to bedside to physiology

    Han, J., Neufer, D. & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 135

    Research output: Contribution to journal › Editorial › Research › peer-review

  30. Published

    Fibroblasts direct differentiation of human breast epithelial progenitors

    Morsing, M., Kim, Jiyoung, Villadsen, René, Goldhammer, N., Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2020, In: Breast Cancer Research. 22, 16 p., 102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Functional characterization of the first missense variant in CEP78, a founder allele associated with cone-rod dystrophy, hearing loss and reduced male fertility

    Ascari, G., Peelman, F., Farinelli, P., Rosseel, T., Lambrechts, N., Wunderlich, K. A., Wagner, M., Nikopoulos, K., Martens, P., Balikova, I., Derycke, L., Holtappels, G., Krysko, O., Van Laethem, T., De Jaegere, S., Guillemyn, B., De Rycke, R., De Bleecker, J., Creytens, D., Van Dorpe, J. & 11 others, Gerris, J., Bachert, C., Neuhofer, C., Walraedt, S., Bischoff, A., Pedersen, Lotte Bang, Klopstock, T., Rivolta, C., Leroy, B. P., De Baere, E. & Coppieters, F., 2020, In: Human Mutation. 41, 5, p. 998-1011 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Fundamentals of Bicarbonate Secretion in Epithelia

    Novak, Ivana & Praetorius, J., 2020, Basic Epithelial Ion TransportPrinciples and Function: Ion Channels and Transporters of Epitheliain Health and Disease. Hamilton, K. L. & Devor, D. C. (eds.). 2. ed. Springer, Vol. 1. p. 461-541 (Physiology in Health and Disease).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  33. Published

    Hepatic PGC-1α is not essential for fasting-induced cytochrome p450 regulation in mouse liver

    Thøgersen, R., Maag Kristensen, C., Olsen, M. A., Bertram, H. C., Pilegaard, Henriette & Rasmussen, M. K., 2020, In: Biochemical Pharmacology. 172, 7 p., 113736.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

    Björkman, A., Johansen, S. L., Lin, L., Schertzer, M., Kanellis, D. C., Katsori, A., Christensen, Søren Tvorup, Luo, Y., Andersen, J. S., Elsässer, S. J., Londono-Vallejo, A., Bartek, J. & Schou, K. B., 2020, In: Genes & Development. 34, 15-16, p. 1065-1074 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Impact of skeletal muscle IL-6 on subcutaneous and visceral adipose tissue metabolism immediately after high- and moderate-intensity exercises

    Bertholdt, L., Gudiksen, Anders, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2020, In: Pflügers Archiv - European Journal of Physiology. 472, 2, p. 217-233 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Impact of the histone deacetylase inhibitor trichostatin A on active uptake, volume-sensitive release of taurine, and cell fate in human ovarian cancer cells

    Lambert, Ian Henry, Nielsen, D. & Stürup, Stefan, 2020, In: American journal of physiology. Cell physiology. 318, 3, p. C581-C597

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

    Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2x2 factorial, randomised, crossover study in human individuals

    Hjelholt, A. J., Charidemou, E., Griffin, J. L., Pedersen, S. B., Gudiksen, Anders, Pilegaard, Henriette, Jessen, N., Møller, N. & Jørgensen, J. O. L., 2020, In: Diabetologia. 63, 12, p. 2641-2653 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    New insights into the limited thermotolerance of anhydrobiotic tardigrades

    Cardoso Neves, R. A., Stuart, R. M. & Møbjerg, Nadja, 2020, In: Communicative & Integrative Biology. 13, 1, p. 140-146

    Research output: Contribution to journal › Letter › Research › peer-review

  40. Published

    O-glycan initiation directs distinct biological pathways and controls epithelial differentiation

    Bagdonaite, Ieva , Pallesen, E. M. H., Ye, Z., Vakhrushev, Sergey, Marinova, I. N., Nielsen, Mathias Alexander Ingemann, Kramer, S. H., Pedersen, Stine Helene Falsig, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2020, In: EMBO Reports. 21, 6, 17 p., e48885.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Ongoing revision of Echiniscoididae (Heterotardigrada: Echiniscoidea), with the description of a new interstitial species and genus with unique anal structures

    Møbjerg, Nadja, Jørgensen, Aslak & Kristensen, Reinhardt Møbjerg, 2020, In: Zoological Journal of the Linnean Society . 188, 3, p. 663-680 18 p., zlz122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    PGC-1α-mediated regulation of mitochondrial function and physiological implications

    Halling, Jens Frey & Pilegaard, Henriette, 2020, In: Applied Physiology, Nutrition and Metabolism. 45, 9, p. 927-936 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration

    Tozzi, M., Hansen, Jacob B. & Novak, Ivana, 2020, In: Acta Physiologica. 228, 2, 18 p., e13360.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Proton Pump Inhibitors Reduce Pancreatic Adenocarcinoma Progression by Selectively Targeting H+, K+-ATPases in Pancreatic Cancer and Stellate Cells

    Tozzi, M., Sørensen, Christiane Elisabeth, Magni, Lara, Christensen, Nynne, Bouazzi, R., Buch, C. M., Stefanini, M., Duranti, C., Arcangeli, A. & Novak, Ivana, 2020, In: Cancers. 12, 3, 22 p., 640.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Purification and initial characterization of Plasmodium falciparum K+ channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae

    Molbaek, K., Tejada, M., Ricke, C. H., Scharff-Poulsen, P., Ellekvist, P., Helix-Nielsen, C., Kumar, N., Klærke, Dan Arne & Pedersen, Per Amstrup, 2020, In: Microbial Cell Factories. 19, 1, 183.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Purinergic Signaling in Pancreas - From Physiology to Therapeutic Strategies in Pancreatic Cancer

    Novak, Ivana, Yu, Haoran, Magni, Lara & Deshar, Ganga, 2020, In: International Journal of Molecular Sciences (Online). 21, 22, 21 p., 8781.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1

    Rolver, M. G., Elingaard-Larsen, L. O., Andersen, Anne Poder, Counillon, L. & Pedersen, Stine Helene Falsig, 2020, In: Scientific Reports. 10, 17 p., 5800.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes

    Isidor, Marie Sophie, Winther, Sally, Markussen, L. K., Basse, A. L., Quistorff, B., Nedergaard, J., Emanuelli, Brice & Hansen, Jacob B., 2020, In: FEBS Letters. 594, 7, p. 1218-1225

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

    Farooq, M., Lindbæk, L., Krogh, N., Doganli, C., Keller, C., Mönnich, M., Gonçalves, A. B., Sakthivel, S., Mang, Y., Fatima, A., Andersen, V. S., Hussain, M. S., Eiberg, H., Hansen, L., Kjaer, K. W., Gopalakrishnan, J., Pedersen, L. B., Møllgård, K., Nielsen, H., Baig, S. M. & 3 others, Tommerup, Niels, Christensen, Søren Tvorup & Larsen, Lars Allan, 2020, In: Nature Communications. 11, 16 p., 5816.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet

    Kellard, J. A., Rorsman, N. J. G., Hill, T. G., Armour, Sarah Louise, van de Bunt, M., Rorsman, P., Knudsen, Jakob Grunnet & Briant, L. J. B., 2020, In: Molecular Metabolism. 40, 13 p., 101021.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae

    Prada Luengo, Inigo, Møller, H. D., Henriksen, Rasmus Henrik Amund, Gao, Q., Larsen, C. E., Alizadeh, S., Maretty, L., Houseley, J. & Regenberg, Birgitte, 2020, In: Nucleic Acids Research. 48, 14, p. 7883-7898 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Research presented at the 14th International Symposium on Tardigrada: progress in studies on water bears

    Møbjerg, Nadja, Michalczyk, Ł., McInnes, S. J. & Christenhusz, M. J. M., 2020, In: Zoological Journal of the Linnean Society . 188, 3, p. 655-662

    Research output: Contribution to journal › Editorial › Research › peer-review

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