Cell Biology and Physiology

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  1. 1999
  2. Published

    Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR

    de Bruin, M., Miyake, K., Litman, Thomas, Robey, R. & Bates, S. E., 15 Nov 1999, In: Cancer Letters. 146, 2, p. 117-26 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

    Brangi, M., Litman, Thomas, Ciotti, M., Nishiyama, K., Kohlhagen, G., Takimoto, C., Robey, R., Pommier, Y., Fojo, T. & Bates, S. E., 1 Dec 1999, In: Cancer Research. 59, 23, p. 5938-46 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2000
  5. Published

    Calcium ion in skeletal muscle: its crucial role for muscle function, plasticity, and disease

    Berchtold, Martin Werner, Brinkmeier, H. & Müntener, M., 2000, In: Physiological Reviews. 80, 3, p. 1215-65 50 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Ceramide-induced TCR up-regulation

    Bonefeld, Charlotte Menne, Lauritsen, J. P. H., Dietrich, J., Kastrup, J., Wegener, A. M., Ødum, Niels & Geisler, Carsten, 2000, In: Journal of Immunology. 165, 6, p. 3065-72 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Effect of cytochalasins on F-actin and morphology of Ehrlich ascites tumor cells.

    Mills, J. W., Pedersen, Stine Helene Falsig, Walmod, P. S. & Hoffmann, E. K., 2000, In: Experimental Cell Research. 261, 1, p. 209-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Exercise-induced translocation of Na+-K+ pump subunits to the plasma membrane in human skeletal muscle

    Juel, C., Nielsen, Jens Jung & Bangsbo, Jens, 2000, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 278, 4, p. R1107-R1110 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  9. Published

    IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells

    Skov, S., Bonyhadi, M., Ødum, Niels & Ledbetter, J. A., 2000, In: Journal of Immunology. 164, 7, p. 3500-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Interstitial K+ in human skeletal muscle during and after dynamic graded exercise determined by microdialysis

    Juel, C., Pilegaard, Henriette, Nielsen, Jens Jung & Bangsbo, Jens, 2000, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 278, 2, p. R400-R406 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter

    Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, 4, p. 1137-46 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Low prevalence of antibodies and other plasma factors binding to CC chemokines and IL-2 in HIV-positive patients

    Meyer, C. N., Svenson, M., Schade Larsen, C., Ødum, Niels, Skinhøj, P. & Bendtzen, K., 2000, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 108, 2, p. 122-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase

    Lauritsen, J. P. H., Bonefeld, Charlotte Menne, Kastrup, J., Dietrich, J., Ødum, Niels & Geisler, Carsten, 2000, In: BBA General Subjects. 1497, 3, p. 297-307 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

    Rocchi, E., Khodjakov, A., Volk, E. L., Yang, C. H., Litman, Thomas, Bates, S. E. & Schneider, E., 29 Apr 2000, In: Biochemical and Biophysical Research Communications. 271, 1, p. 42-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)

    Litman, Thomas, Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. & Bates, S. E., Jun 2000, In: Journal of Cell Science. 113 ( Pt 11), p. 2011-21 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Characterisation of multidrug-resistant Ehrlich ascites tumour cells selected in vivo for resistance to etoposide

    Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas, Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 353-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone

    Nielsen, D., Eriksen, J., Maare, C., Litman, Thomas, Kjaersgaard, E., Plesner, T., Friche, E. & Skovsgaard, T., 1 Aug 2000, In: Biochemical Pharmacology. 60, 3, p. 363-70 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Importance of conserved α-subunit segment 709GDGVND for Mg2+ binding, phosphorylation, and energy transduction in Na,K-ATPase

    Pedersen, Per Amstrup, Jorgensen, J. R. & Jorgensen, P. L., 1 Dec 2000, In: Journal of Biological Chemistry. 275, 48, p. 37588-37595 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2001
  20. Published

    Calmodulin protects cells from death under normal growth conditions and mitogenic starvation but plays a mediating role in cell death upon B-cell receptor stimulation

    Schmalzigaug, R., Ye, Q. & Berchtold, Martin Werner, 2001, In: Immunology. 103, 3, p. 332-42 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a

    Brockdorff, J. L., Gu, H., Mustelin, T., Kaltoft, K., Geisler, Carsten, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 86-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Induction of cytotoxic CD8+CD56+ T cells from human thymocytes by interleukin-15.

    Thulesen, S., Nissen, Mogens Holst, Ødum, Niels & Röpke, C., 2001, In: Journal of Interferon & Cytokine Research. 21, 11, p. 905-11 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells

    Brender, C., Nielsen, M., Röpke, C., Nissen, M. H., Svejgaard, A., Billestrup, N., Geisler, Carsten & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 2, p. 80-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Oligonucleotide fishing for STAT6: cross-talk between IL-4 and chemokines.

    Eriksen, K. W., Nielsen, M., Kaltoft, K., Svejgaard, A., Nissen, Mogens Holst, Röpke, C. & Ødum, Niels, 2001, In: Experimental and Clinical Immunogenetics. 18, 4, p. 233-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Radically altered T cell receptor signaling in glycopeptide-specific T cell hybridoma induced by antigen with minimal differences in the glycan group

    Jensen, T., Nielsen, M., Gad, M., Hansen, P., Komba, S., Meldal, M., Ødum, Niels & Werdelin, O., 2001, In: European Journal of Immunology. 31, 11, p. 3197-206 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

    Brender, C., Nielsen, M., Kaltoft, K., Mikkelsen, G., Zhang, Q., Wasik, M., Billestrup, N. & Ødum, Niels, 2001, In: Blood. 97, 4, p. 1056-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Superantigen presentation by human retinal pigment epithelial cells to T cells is dependent on CD2-CD58 and CD18-CD54 molecule interactions.

    Jørgensen, A., Junker, N., Kaestel, C. G., Liang, Y., Wiencke, A., la Cour, M., Lui, G. M., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2001, In: Experimental Eye Research. 73, 5, p. 723-33 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion

    Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Bissell, M. J., 2001, In: Breast Cancer Research (Online Edition). 3, p. 213-217

    Research output: Contribution to journal › Review › Research

  29. Published

    The pump and leak steady-state concept with a variety of regulated leak pathways.

    Hoffmann, E. K., 2001, In: Journal of Membrane Biology. 184, 3, p. 321-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

    Robey, R. W., Medina-Pérez, W. Y., Nishiyama, K., Lahusen, T., Miyake, K., Litman, Thomas, Senderowicz, A. M., Ross, D. D. & Bates, S. E., Jan 2001, In: Clinical Cancer Research. 7, 1, p. 145-52 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Structure-function relationships of Na+, K+, ATP, or Mg2+ binding and energy transduction in Na,K-ATPase

    Jorgensen, P. L. & Pedersen, Per Amstrup, 1 May 2001, In: Biochimica et Biophysica Acta - Bioenergetics. 1505, 1, p. 57-74 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes

    Abraham, E. H., Shrivastav, B., Salikhova, A. Y., Sterling, K. M., Johnston, N., Guidotti, G., Scala, S., Litman, Thomas, Chan, K. C., Arceci, R. J., Steiglitz, K., Herscher, L. & Okunieff, P., 19 May 2001, In: Blood Cells, Molecules and Diseases. 27, 1, p. 181-200 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance

    Litman, Thomas, Druley, T. E., Stein, W. D. & Bates, S. E., Jun 2001, In: Cellular and molecular life sciences : CMLS. 58, 7, p. 931-59 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)

    Robey, R. W., Honjo, Y., van de Laar, A., Miyake, K., Regis, J. T., Litman, Thomas & Bates, S. E., 6 Jun 2001, In: BBA General Subjects. 1512, 2, p. 171-82 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Role of phylogenetically conserved amino acids in folding of Na,K-ATPase

    Jørgensen, J. R. & Pedersen, Per Amstrup, 19 Jun 2001, In: Biochemistry. 40, 24, p. 7301-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

    Ozvegy, C., Litman, Thomas, Szakács, G., Nagy, Z., Bates, S., Váradi, A. & Sarkadi, B., 6 Jul 2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 111-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells

    Honjo, Y., Hrycyna, C. A., Yan, Q. W., Medina-Pérez, W. Y., Robey, R. W., van de Laar, A., Litman, Thomas, Dean, M. & Bates, S. E., 15 Sep 2001, In: Cancer Research. 61, 18, p. 6635-6639 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Reversibility of exercise-induced translocation of Na+-K+ pump subunits to the plasma membrane in rat skeletal muscle

    Juel, C., Grunnet, Louise Groth, Holse, M., Kenworthy, S., Sommer, V. & Wulff, T., Nov 2001, In: Pflügers Archiv - European Journal of Physiology. 443, 2, p. 212-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation

    Nielsen, D., Maare, C., Eriksen, J., Litman, Thomas & Skovsgaard, T., 15 Nov 2001, In: International Journal of Radiation Oncology, Biology, Physics. 51, 4, p. 1050-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The role of half-transporters in multidrug resistance

    Bates, S. E., Robey, R., Miyake, K., Rao, K., Ross, D. D. & Litman, Thomas, Dec 2001, In: Journal of Bioenergetics and Biomembranes. 33, 6, p. 503-11 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2002
  42. Published

    Control of Cl- transport in the operculum epithelium of Fundulus heteroclitus: long- and short-term salinity adaptation.

    Hoffmann, E. K., Hoffmann, E., Lang, F. & Zadunaisky, J. A., 2002, In: BBA General Subjects. 1566, 1-2, p. 129-39 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-β1-mediated conversion of fibroblasts to myofibroblasts

    Rønnov-Jessen, Lone, Villadsen, René, Edwards, J. C. & Petersen, Ole William, 2002, In: American Journal of Pathology. 161, 2, p. 471-480 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

    Bonefeld, Charlotte Menne, Møller Sørensen, T., Siersma, Volkert Dirk, von Essen, Marina Rode, Ødum, Niels & Geisler, Carsten, 2002, In: European Journal of Immunology. 32, 3, p. 616-26 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Human retinal pigment epithelial cells inhibit proliferation and IL2R expression of activated T cells.

    Kaestel, C. G., Jørgensen, A., Nielsen, M., Eriksen, K. W., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Experimental Eye Research. 74, 5, p. 627-37 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    IL-15 induces unspecific effector functions in human peptide-specific CD8+ T-cell cultures.

    Lyngstrand, S. T., Würtzen, P. A., Ødum, Niels, Nissen, Mogens Holst & Röpke, C., 2002, In: Scandinavian Journal of Immunology. 56, 6, p. 602-10 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer

    Nielsen, H. L., Rønnov-Jessen, Lone, Villadsen, René & Petersen, Ole William, 2002, In: Genomics. 79, 5, p. 703-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling

    Dietrich, J., Bonefeld, Charlotte Menne, Lauritsen, J. P. H., von Essen, Marina Rode, Rasmussen, B. A., Ødum, Niels & Geisler, Carsten, 2002, In: Journal of Immunology. 168, 11, p. 5434-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Mechanisms of activation of NHE by cell shrinkage and by calyculin A in Ehrlich ascites tumor cells.

    Pedersen, Stine Helene Falsig, Varming, C., Christensen, Søren Tvorup & Hoffmann, E. K., 2002, In: Journal of Membrane Biology. 189, 1, p. 67-81 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

    Zhang, Q., Raghunath, P. N., Xue, L., Majewski, M., Carpentieri, D. F., Ødum, Niels, Morris, S., Skorski, T. & Wasik, M. A., 2002, In: Journal of Immunology. 168, 1, p. 466-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Possible interrelationship between changes in F-actin and myosin II, protein phosphorylation, and cell volume regulation in Ehrlich ascites tumor cells.

    Pedersen, S. F. & Hoffmann, E. K., 2002, In: Experimental Cell Research. 277, 1, p. 57-73 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling

    Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts.

    Pedersen, Stine Helene Falsig, Beisner, K. H., Willumsen, Berthe Marie, Lambert, Ian Henry & Hoffmann, E. K., 2002, In: Journal of Physiology. 541, Pt 3, p. 779-96 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.

    Carton, I., Trouet, D., Hermans, D., Barth, H., Aktories, K., Droogmans, G., Jorgensen, N. K., Hoffmann, E. K., Nilius, B. & Eggermont, J., 2002, In: American Journal of Physiology: Cell Physiology. 283, 1, p. C115-C125

    Research output: Contribution to journal › Journal article › Research › peer-review

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