Cell Biology and Physiology

  1. 2019
  2. Published

    Skeletal muscle interleukin 6 in fasting and exercise-induced metabolic regulation in liver and adipose tissue

    Bertholdt, L., 2019, Department of Biology, Faculty of Science, University of Copenhagen. 179 p.

    Research output: Book/ReportPh.D. thesisResearch

  3. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The Na+/H+ exchanger NHE1 localizes as clusters to cryptic lamellipodia and accelerates collective epithelial cell migration

    Jensen, H. H., Pedersen, G. A., Morgen, J. J., Parsons, M., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2019, In: Journal of Physiology. 597, 3, p. 849-867

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The SLC9A-C Mammalian Na+/H+ Exchanger Family: Molecules, Mechanisms, and Physiology

    Pedersen, Stine Helene Falsig & Counillon, L., 2019, In: Physiological Reviews. 99, 4, p. 2015-2113 99 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. 2018
  7. Published

    Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

    Møller, H. D., Mohiyuddin, M., Prada Luengo, Inigo, Sailani, M. R., Halling, Jens Frey, Plomgaard, Peter Stendahl, Maretty, L., Hansen, Anders Johannes, Snyder, M. P., Pilegaard, Henriette, Lam, H. Y. K. & Regenberg, Birgitte, 1 Dec 2018, In: Nature Communications. 9, 12 p., 1069.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Training state and skeletal muscle autophagy in response to 36 h of fasting

    Dethlefsen, M. M., Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Bangsbo, Jens, van Hall, Gerrit, Plomgaard, Peter Stendahl & Pilegaard, Henriette, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1609-1619 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers

    Kjeld, T., Stride, N., Gudiksen, Anders, Hansen, E. G., Arendrup, H. C., Horstmann, P. F., Zerahn, B., Jensen, Lars Thorbjørn, Nordsborg, Nikolai Baastrup, Bejder, Jacob & Halling, Jens Frey, 19 Sep 2018, In: P L o S One. 13, 9, p. 1-13 13 p., e0201401.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Facilitating the Cellular Accumulation of Pt-Based Chemotherapeutic Drugs

    Lambert, Ian Henry & Sørensen, B. H., 1 Aug 2018, In: International Journal of Molecular Sciences . 19, 8, p. 1-19 2249.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Genetic Analysis of Signal Generation by the Rgt2 Glucose Sensor of Saccharomyces cerevisiae

    Scharff-Poulsen, P., Moriya, H. & Johnston, M., 1 Aug 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 8, p. 2685-2696 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Impact of β-adrenergic signaling in PGC-1α-mediated adaptations in mouse skeletal muscle

    Brandt, N., Nielsen, L., Buch, B. T., Gudiksen, Anders, Jørgensen, Stine Ringholm, Hellsten, Ylva, Bangsbo, Jens & Pilegaard, Henriette, 1 Jan 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E1-E20 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(II) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis

    Sørensen, B. H., Werth, P., Lambert, Ian Henry & Bednarski, P. J., 2018, In: Metallomics. 10, 2, p. 323-336 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment

    la Cour, J. M., Gojkovic, P. W., Ambjorner, S. E. B., Bagge, J., Jensen, S. M., Panina, S. & Berchtold, Martin Werner, 2018, In: PLOS ONE. 13, 9, p. 1-13 e0204520.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2

    Højfeldt, J. W., Laugesen, A., Willumsen, Berthe Marie, Damhofer, H., Hedehus, L., Tvardovskiy, A., Mohammad, F., Jensen, O. N. & Helin, K., 2018, In: Nature Structural & Molecular Biology. 25, p. 225-232 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

    Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.

    Research output: Contribution to journalComment/debateResearchpeer-review

  17. Published

    Beta2-adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men

    Hostrup, Morten, Reitelseder, S., Jessen, Søren Kaare, Kalsen, A., Nyberg, M. P., Egelund, J., Kreiberg, M., Maag Kristensen, C., Thomassen, Martin, Pilegaard, Henriette, Backer, Vibeke, Jacobson, G. A., Holm, L. & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 17, p. 4121-4139 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

    Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    CRISPR-C: circularization of genes and chromosome by CRISPR in human cells

    Møller, H. D., Lin, L., Xiang, X., Petersen, T. S., Huang, J., Yang, L., Kjeldsen, E., Jensen, U. B., Zhang, X., Liu, X., Xu, X., Wang, J., Yang, H., Church, G. M., Bolund, L., Regenberg, Birgitte & Luo, Y., 2018, In: Nucleic Acids Research. 46, 22, p. 1-13 e131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Calmodulin as a protein linker and a regulator of adaptor/scaffold proteins

    Villalobo, A., Ishida, H., Vogel, H. J. & Berchtold, Martin Werner, 2018, In: B B A - Molecular Cell Research. 1865, 3, p. 507-521 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Characterization of Taurine Transporting Systems During Acquirement of Resistance to Platinum(II)-based, Chemotherapeutic Drugs

    Sørensen, B. H., 2018, Department of Biology, Faculty of Science, University of Copenhagen. 190 p.

    Research output: Book/ReportPh.D. thesisResearch

  23. Published

    Deconstructing the principles of ductal network formation in the pancreas

    Dahl-Jensen, Svend Bertel, Yennek, S., Flasse, L., Larsen, Hjalte List, Sever, D., Karremore, G., Novak, Ivana, Sneppen, Kim & Botton, A., 2018, In: PLOS Biology. 16, 7, 25 p., e2002842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Development and validation of an ICP-MS method for quantification of total carbon and platinum in cell samples and comparison of open-vessel and microwave-assisted acid digestion methods

    Riisom, M., Gammelgaard, Bente, Lambert, Ian Henry & Stürup, Stefan, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 158, p. 144-150 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine

    Rubino, S., Bach, M. D., Schober, A. L., Lambert, Ian Henry & Mongin, A. A., 2018, In: Frontiers in Oncology. 8, 12 p., 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Environmental Adaptations: Encystment and Cyclomorphosis

    Guidetti, R. & Møbjerg, Nadja, 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 249-271 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  27. Published

    Exercise and exercise training-induced increase in autophagy markers in human skeletal muscle

    Brandt, N., Gunnarsson, T. G. P., Bangsbo, Jens & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 7, 12 p., e13651.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    From channel proteins to industrial biomimetic membrane technology

    Pedersen, Per Amstrup, Bjørkskov, F. B., Alvisse, S. & Hélix-Nielsen, C., 2018, In: Faraday Discussions. 209, p. 287-301 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    GSK3 is a negative regulator of the thermogenic program in brown adipocytes

    Markussen, L. K., Winther, Sally, Wicksteed, B. & Hansen, Jacob B., 2018, In: Scientific Reports. 8, p. 1-12 3469.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Human AQP5 facilitates hydrogen peroxide permeation and improves cell resistance to oxidative stress

    Rodrigues, C., Mósca, A. F., Lopes, D., Pedersen, Per Amstrup, Antunes, F. & Soveral, G., 2018, In: Free Radical Biology and Medicine. 120, Suppl. 1, p. S70 P-86.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Human adipose glycerol flux is regulated by a pH gate in AQP10

    Gotfryd, K., Mósca, A. F., Missel, Julie Winkel, Truelsen, S. F., Wang, Kaituo, Spulber, M., Krabbe, S., Hélix-nielsen, C., Laforenza, U., Soveral, G., Pedersen, Per Amstrup & Gourdon, Pontus Emanuel, 2018, In: Nature Communications. 9, p. 1-11 4749.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

    Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, Lars Allan, Andersen, J. S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2018, In: Journal of Cell Biology. 217, 1, p. 151-161 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice

    Rasmussen, M. K., Bertholdt, L., Gudiksen, Anders, Pilegaard, Henriette & Knudsen, Jakob Grunnet, 2018, In: Toxicology Letters. 282, p. 93-99 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Impact of liver PGC-1α on exercise and exercise training-induced regulation of hepatic autophagy and mitophagy in mice on HFF

    Dethlefsen, M. M., Kristensen, C. M., Tondering, A. S., Lassen, S. B., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 13, p. 1-16 e13731.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting

    Bertholdt, L., Gudiksen, Anders, Jessen, H. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 11, p. 1597-1613

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans

    Bertholdt, L., Gudiksen, Anders, Stankiewicz, T., Villesen, I., Tybirk, J., van Hall, Gerrit, Bangsbo, Jens, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2018, In: Journal of Applied Physiology. 124, 3, p. 729-740 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Metabolic stress-dependent regulation of the mitochondrial biogenic molecular response to high-intensity exercise in human skeletal muscle

    Fiorenza, Matteo, Gunnarsson, T. P., Hostrup, Morten, Iaia, F. M., Schena, F., Pilegaard, Henriette & Bangsbo, Jens, 2018, In: Journal of Physiology. 596, 14, p. 2823-2840 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Metformin targets brown adipose tissue in vivo and reduces oxygen consumption in vitro

    Breining, P., Jensen, J. B., Sundelin, E. I., Gormsen, L. C., Jakobsen, S., Busk, M., Rolighed, L., Bross, P., Fernandez-Guerra, P., Markussen, L. K., Rasmussen, N. E., Hansen, Jacob B., Pedersen, S. B., Richelsen, B. & Jessen, N., 2018, In: Diabetes, Obesity and Metabolism. 20, 9, p. 2264-2273

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Modelling extreme desiccation tolerance in a marine tardigrade

    Sørensen-Hygum, T. L., Stuart, R. M., Jørgensen, Aslak & Møbjerg, Nadja, 2018, In: Scientific Reports. 8, 9 p., 11495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Morphology and Functional Anatomy

    Møbjerg, Nadja, Jørgensen, Aslak, Kristensen, Reinhardt Møbjerg & Cardoso Neves, R. A., 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 57-94 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  41. Published

    Muscle PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Maag Kristensen, C., Jessen, H., Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Acta Physiologica. 224, 4, p. 1-17 e13158.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Na+,HCO3--cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

    Lee, S., Axelsen, T. V., Jesse, N., Pedersen, Stine Helene Falsig, Vahl, P. & Boedtkjer, E., 2018, In: Oncogene. 37, 41, p. 5569-5584

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    P2X receptor-ion channels in the inflammatory response in adipose tissue and pancreas-potential triggers in onset of type 2 diabetes?

    Novak, Ivana & Solini, A., 2018, In: Current Opinion in Immunology. 52, p. 1-7 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    PGC-1α in exercise and fasting-induced regulation of hepatic UPR in mice

    Kristensen, C. M., Olsen, M. A., Jessen, H., Brandt, N., Meldgaard, J. N. & Pilegaard, Henriette, 2018, In: Pflügers Archiv - European Journal of Physiology. 470, 10, p. 1431-1447

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    PGC-1α in hepatic UPR during high-fat high-fructose diet and exercise training in mice

    Kristensen, C. M., Dethlefsen, M. M., Tøndering, A. S., Lassen, S. B., Meldgaard, J. N., Ringholm, S. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 15, p. 1-15 e13819.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Phylogeny and Integrative Taxonomy of Tardigrada

    Jørgensen, Aslak, Kristensen, Reinhardt Møbjerg & Møbjerg, Nadja, 2018, Water Bears: The Biology of Tardigrades. Schill, R. O. (ed.). Springer, p. 95-114 (Zoological Monographs, Vol. 2).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  47. Published

    Prior exercise training improves cold tolerance independent of indices associated with non-shivering thermogenesis

    Knuth, C. M., Peppler, W. T., Townsend, L. K., Miotto, P. M., Gudiksen, Anders & Wright, D. C., 2018, In: The Journal of Physiology. 596, 18, p. 4375-4391

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

    Klærke, Dan Arne, Tejada, M. D. L. A., Christensen, V. G., Lassen, M., Pedersen, Per Amstrup & Callø, Kirstine, 2018, In: Current Protocols in Pharmacology. 81, 1, p. e37 17 p., e37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

    Dethlefsen, M. M., Halling, Jens Frey, Møller, H. D., Plomgaard, Peter Stendahl, Regenberg, Birgitte, Jørgensen, Stine Ringholm & Pilegaard, Henriette, 2018, In: Experimental Gerontology. 111, p. 141-153

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

    Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2018, In: F E B S Journal. 285, 24, p. 4535-4564

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Regulation of vesicle trafficking at the primary cilium

    Morthorst, Stine Kjær, 2018, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  52. Published

    Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

    Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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