Cell Biology and Physiology

  1. 2014
  2. Published

    Effect of gastrointestinal protease digestion on bioactivity of marine peptides

    Jensen, I., Andersen, L. L., Ossum, C., Jakobsen, G., De Gobba, Cristian, Habeebullah, S. F. K., Johansson, I., Hoffmann, E. K., Elvevoll, E. O., Jessen, F. & Nielsen, H. H., 2014, In: Journal of Agricultural Science and Technology. B. 4, p. 74-84 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    ErbB2 upregulates the Na+,HCO3- -cotransporter NBCn1/SLC4A7 in human breast cancer cells via Akt, ERK, Src, and Krüppel-like factor 4

    Gorbatenko, A., Olesen, C. W., Mørup, N., Thiel, G., Kallunki, T., Valen, E. & Pedersen, Stine Helene Falsig, 2014, In: F A S E B Journal. 28, 1, p. 350-363 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Expression of TGF-beta superfamily growth factors, their receptors, the associated SMADs and antagonists in five isolated size-matched populations of pre-antral follicles from normal human ovaries

    Kristensen, S. G., Andersen, Kasper Langebjerg, Clement, C. A., Franks, S., Hardy, K. & tcg964, tcg964, 2014, In: Molecular Human Reproduction. 20, 4, p. 293-308 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Functions of volume-sensitive and calcium-activated chloride channels

    Hoffmann, E. K., Holm, N. B. & Lambert, Ian Henry, 2014, In: I U B M B Life. 66, 4, p. 257-267 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Identification of conserved, centrosome-targeting ASH domains in TRAPPII complex subunits and TRAPPC8

    Schou, K. B., Morthorst, Stine Kjær, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2014, In: Cilia. 3, 6, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birth weight

    Schultz, N. S., Broholm, C., Gillberg, L., Mortensen, B., Jørgensen, S. W., Schultz, H. S., Schéele, Camilla Charlotte Nielsen, Wojtaszewski, Jørgen F P, Pedersen, Bente Klarlund & Vaag, Allan, 2014, In: Diabetes. 63, 1, p. 111-121 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J Mice

    Fjære, E., Aune, U. L., Røen, K., Keenan, A. H., Ma, Tao, Borkowski, K., Kristensen, D. M. B., Novotny, G. W., Mandrup-Poulsen, Thomas, Hudson, B. D., Milligan, G., Xi, Y., Newman, J. W., Haj, F. G., Liaset, B., Kristiansen, Karsten & Madsen, L., 2014, In: The Journal of Biological Chemistry. 289, 23, p. 16032-16045 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Ion channels and transporters in the development of drug resistance in cancer cells

    Hoffmann, E. K. & Lambert, Ian Henry, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Kif7 keeps cilia tips in shape

    Pedersen, Lotte Bang & Akhmanova, A., 2014, In: Nature Cell Biology. 16, 7, p. 623-625 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair

    Schreml, S., Meier, R. J., Kirschbaum, M., Kong, S. C., Gehmert, S., Felthaus, O., Kuechler, S., Sharpe, J. R., Woeltje, K., Weiss, K. T., Albert, M., Seidl, U., Schroeder, J., Morsczeck, C., Prantl, L., Duschl, C., Pedersen, S. H. F., Gosau, M., Berneburg, M., Wolfbeis, O. S. & 2 others, Landthaler, M. & Babilas, P., 2014, In: Theranostics. 4, 7, p. 721-735 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Novel roles of the Na+/H+ exchanger NHE1 and the Na+,HCO3 - cotransporter NBCn1 in cell survival, proliferation and motility

    Thorup, G. E., 2014, Department of Biology, Faculty of Science, University of Copenhagen. 146 p.

    Research output: Book/ReportPh.D. thesisResearch

  14. Published

    Phosphorylation of rat melanopsin at Ser-381 and Ser-398 by light/dark and its importance for intrinsically photosensitive ganglion cells (ipRGCs) cellular Ca2+ signaling

    Fahrenkrug, J., Falktoft, B., Georg, B., Hannibal, Jens, Kristiansen, S. B. & Klausen, T. K., 2014, In: Journal of Biological Chemistry. 289, 51, p. 35482-35493 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Proteomic analysis of bovine blastocoel fluid and blastocyst cells

    Jensen, P. L., Grøndahl, M. L., Beck, H. C., Petersen, J., Stroebech, L., Christensen, Søren Tvorup & tcg964, tcg964, 2014, In: Systems Biology in Reproductive Medicine. 60, 3, p. 127-135 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Quantitative proteomics at different depths in human articular cartilage reveals unique patterns of protein distribution

    Müller, C., Khabut, A., Dudhia, J., Reinholt, F. P., Aspberg, A., Heinegard, D. & Önnerfjord, P., 2014, In: Matrix Biology. 40, p. 34-45 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Regulation and roles of bicarbonate transporters in cancer

    Gorbatenko, A., Olesen, C. W., Bødtkjer, E. & Pedersen, Stine Helene Falsig, 2014, In: Frontiers in Physiology. 5, 15 p., 130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    STAT3 activation and infiltration of eosinophil granulocytes in mycosis fungoides

    Fredholm, S., Gjerdrum, Lise Mette Rahbek, Willerslev-Olsen, A., Petersen, D. L., Nielsen, I. Ø., Kauczok, C., Wobser, M., Ralfkiaer, U., Bonefeld, Charlotte Menne, Wasik, M. A., Krejsgaard, T., Geisler, Carsten, Ralfkiaer, E., Gniadecki, R., Woetmann, Anders & Ødum, Niels, 2014, In: Anticancer Research. 34, 10, p. 5277-5286 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

    Klausen, T. K., Janssens, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig & Nilius, B., 2014, In: Cell Calcium. 55, 1, p. 38-47 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structual Dynamics and Function of the Na+/H+ Exchanger 1

    Hendus-Altenburger, R., 2014, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  21. Published

    Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers

    Hendus-Altenburger, R., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2014, Current Topics in Membranes: Exchangers. Bevensee, M. O. (ed.). Elsevier, Vol. 73. p. 69-148 80 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer

    Berchtold, Martin Werner & Villalobo, A., 2014, In: B B A - Molecular Cell Research. 1843, 2, p. 398-435 38 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis

    Kypri, E., Christodoulou, A., Maimaris, G., Lethan, M., Markaki, M., Lysandrou, C., Lederer, C., Tavernarakis, N., Geimer, S., Pedersen, Lotte Bang & Santama, N., 2014, In: Cellular and molecular life sciences : CMLS. 71, 3, p. 517-538 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Urokinase plasminogen activator is a central regulator of macrophage three-dimensional invasion, matrix degradation, and adhesion

    Fleetwood, A. J., Achuthan, A., Schultz, H. S., Nansen, A., Almholt, K., Usher, P. & Hamilton, J. A., 2014, In: Journal of Immunology. 192, 8, p. 3540-3547 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas

    Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells

    Kongsbak-Wismann, Martin, von Essen, Marina Rode, Boding, L., Levring, T. B., Schjerling, Peter, Lauritsen, J. P. H., Woetmann, Anders , Ødum, Niels, Bonefeld, Charlotte Menne & Geisler, Carsten, 2014, In: PLOS ONE. 9, 5, p. 1-12 13 p., e96695.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    mTOR ensures increased release and reduced uptake of the organic osmolyte taurine under hypoosmotic conditions in mouse fibroblasts

    Lambert, Ian Henry, Jensen, J. V. & Pedersen, Per Amstrup, 2014, In: American Journal of Physiology: Cell Physiology. 306, 11, p. C1028-C1040 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2013
  29. Published

    Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase

    Larsen, B. R., Steffensen, S. D. R., Nielsen, N. V. L., Friis, S., Godiksen, S., Lange, Jette Bornholdt, Soendergaard, C., Nonboe, Annika Weile, Andersen, M. N., Poulsen, Steen Seier, Szabo, R., Bugge, T. H., Lin, C., Skovbjerg, H., Jensen, J. K. & Vogel, Lotte, 1 Apr 2013, In: Experimental Cell Research. 319, 6, p. 918-929 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A Matriptase-Prostasin Reciprocal Zymogen Activation Complex with Unique Features: PROSTASIN AS A NON-ENZYMATIC CO-FACTOR FOR MATRIPTASE ACTIVATION

    Friis, S., Uzzun Sales, K., Godiksen, S., Peters, D. E., Lin, C., Vogel, Lotte & Bugge, T. H., 2013, In: The Journal of Biological Chemistry. 288, 26, p. 19028-19039 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    A unifying mechanism for Cancer cell death through ion channel activation by HAMLET

    Storm, P., Klausen, T. K., Trulsson, M., Ho CS, J., Dosnon, M., Westergren, T., Chao, Y., Rydström, A., Yang, H., Pedersen, Stine Helene Falsig & Svanborg, C., 2013, In: P L o S One. 8, 3, 18 p., e58578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex

    la Cour, J. M., Schindler, A. J., Berchtold, Martin Werner & Schekman, R., 2013, In: P L o S One. 8, 9, 8 p., e75309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Analysis of microtubule plus-end-tracking proteins in cilia

    Larsen, J., Grigoriev, I., Akhmanova, A. & Pedersen, Lotte Bang, 2013, Cilia, Part A. Marshall, W. F. (ed.). Elsevier, p. 105-122 18 p. (Methods in Enzymology, Vol. 524).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  34. Published

    Analysis of primary cilia in directional cell migration in fibroblasts

    Christensen, Søren Tvorup, Veland, I., Schwab, A., Cammer, M. & Satir, P., 2013, In: Methods in Enzymology. 525, p. 45-58 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Cell volume regulation in epithelial physiology and cancer

    Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Novak, Ivana, 2013, In: Frontiers in Physiology. 4, 12 p., 233.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    CrossTalk proposal: cell volume changes are an essential step in the cell death machinery

    Lang, F. & Hoffmann, E. K., 2013, In: Journal of Physiology. 591, 24, p. 6119-6121 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  38. Published

    Differential effects of decoy receptor- and antibody-mediated tumour necrosis factor blockage on FoxP3 expression in responsive arthritis patients

    Ryder, L. R., Ryder, L. P., Bartels, E. M., Woetmann, Anders , Madsen, H. O., Ødum, Niels, Danneskiold-Samsøe, B., Ribel-Madsen, S. & Bliddal, Henning, 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 121, 4, p. 337-347 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo controlled bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown and increased IL-6 release

    Bach, E., Nielsen, R. R., Vendelbo, M., Møller, A. B., Jessen, N., Buhl, M., Hafstrøm, T. K., Holm, L., Pedersen, S. B., Pilegaard, Henriette, Biensøe, R. S., Jørgensen, J. O. L. & Møller, N., 2013, In: Diabetes. 62, 12, p. 4023-4029

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

    Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

    Ly, D. L., Waheed, F., Lodyga, M., Speight, P., Masszi, A., Nakano, H., Hersom, M. N. S., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2013, In: American Journal of Physiology: Cell Physiology. 304, 2, p. C115-C127 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Intake of farmed Atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

    Midtbø, L. K., Ibrahim, M. M., Myrmel, L. S., Aune, U. L., Alvheim, A. R., Liland, N. S., Torstensen, B. E., Rosenlund, G., Liaset, B., Brattelid, T., Kristiansen, Karsten & Madsen, L., 2013, In: P L o S One. 8, 1, 11 p., e53094.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential

    Pedersen, Stine Helene Falsig & Stock, C., 2013, In: Cancer Research. 73, 6, p. 1658-1661 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Isolation and differentiation of stromal vascular cells to beige/brite cells

    Aune, U. L., Ruiz, L. & Kajimura, S., 2013, In: Journal of Visualized Experiments. 73, e50191.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    KCNK5 in Physiology and Pathophysiology: Focus on Cell Volume Control

    Kirkegaard, S. S., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 120 p.

    Research output: Book/ReportPh.D. thesisResearch

  47. Published

    KCNK5 is functionally down-regulated upon long-term hypotonicity in Ehrlich ascites tumor cells

    Kirkegaard, S. S., Wulff, T., Gammeltoft, S. & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 32, 5, p. 1238-1246 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Primary Cilia, Signaling Networks and Cell Migration

    Veland, I. R., 2013, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  50. Published

    Proteomic analysis of human blastocoel fluid and blastocyst cells

    Jensen, P., Beck, H. C., Petersen, J., Hreinsson, J., Wånggren, K., Laursen, S. B., Sørensen, P. D., Christensen, Søren Tvorup & tcg964, tcg964, 2013, In: Stem Cells and Development. 22, 7, p. 1126-1135 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Quantifying changes in the cellular thiol-disulfide status during differentiation of B cells into antibody-secreting plasma cells

    Hansen, R. R. E., Otsu, M., Braakman, I. & Winther, Jakob R., 2013, In: International Journal of Cell Biology. 2013, 10 p., 898563.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Rebuttal from Florian Lang and Else K. Hoffmann

    Lang, F. & Hoffmann, E. K., 2013, In: Journal of Physiology. 591, 24, p. 6127 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

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