Cell Biology and Physiology

  1. 2023
  2. Published

    Lymph Vessels Associate with Cancer Stem Cells from Initiation to Malignant Stages of Squamous Cell Carcinoma

    Cazzola, Anna, Calzón Lozano, D., Menne, D. H., Dávila Pedrera, R., Liu, J., Peña-Jiménez, D., Fontenete, S., Halin, C. & Perez-Moreno, Mirna, 2023, In: International Journal of Molecular Sciences. 24, 17, 20 p., 13615.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Metabolic regulation of glucagon secretion

    Armour, Sarah Louise, Stanley, J. E., Cantley, J., Dean, E. D. & Knudsen, Jakob Grunnet, 2023, In: The Journal of endocrinology. 259, 1, 15 p., e230081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Muscle PGC-1α modulates hepatic mitophagy regulation during aging

    Christensen, N. M., Jørgensen, Stine Ringholm, Buch, B. T., Gudiksen, Anders, Halling, Jens Frey & Pilegaard, Henriette, 2023, In: Experimental Gerontology. 172, 9 p., 112046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    New insights into osmobiosis and chemobiosis in tardigrades

    Hvidepil, L. K. B. & Møbjerg, Nadja, 2023, In: Frontiers in Physiology. 14, 9 p., 1274522.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pharmacological Nature of the Purinergic P2Y Receptor Subtypes That Participate in the Blood Pressure Changes Produced by ADPβS in Rats

    Silva-Velasco, R. C., Villanueva-Castillo, B., Haanes, Kristian Agmund, MaassenVanDenBrink, A. & Villalón, C. M., 2023, In: Pharmaceuticals. 16, 12, 19 p., 1683.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Primary cilia as dynamic and diverse signalling hubs in development and disease

    Mill, P., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2023, In: Nature Reviews. Genetics. 24, 21 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Progesterone distribution in the trigeminal system and its role to modulate sensory neurotransmission: influence of sex

    Maddahi, A., Warfvinge, K., Holm, A., Edvinsson, J. C. A., Reducha, Philip Victor, Kazantzi, Spyridoula, Haanes, Kristian Agmund & Edvinsson, L., 2023, In: Journal of Headache and Pain. 24, 1, 16 p., 154.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes

    Maurer, J., Zhao, X., Irmler, M., Gudiksen, Anders, Pilmark, N. S., Li, Q., Goj, T., Beckers, J., Hrabě De Angelis, M., Birkenfeld, A. L., Peter, A., Lehmann, R., Pilegaard, Henriette, Karstoft, Kristian, Xu, G. & Weigert, C., 2023, In: American Journal of Physiology: Cell Physiology. 325, 4, p. C1131-C1143 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes

    Gheibi, S., Cataldo Bascunan, Luis Rodrigo, Hamilton, Alexander, Huang, M., Kalamajski, S., Fex, M. & Mulder, H., 2023, In: Diabetes. 72, 4, p. 455-466 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Rodent behavior following a dural inflammation model with anti-CGRP migraine medication treatment

    Reducha, Philip Victor, Bömers, J. P., Edvinsson, L. & Haanes, Kristian Agmund, 2023, In: Frontiers in Neurology. 14, 13 p., 1082176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Role of H+,K+ -ATPase and pH-sensitive K2P channels in pancreatic cancer

    Deshar, Ganga, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 114 p.

    Research output: Book/ReportPh.D. thesisResearch

  13. Published

    Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson’s disease

    Ferreira, S. A., Li, Conghui, Klæstrup, I. H., Vitic, Z., Rasmussen, R. K., Kirkegaard, A., Toft, G. U., Betzer, C., Svendsen, P., Jensen, P. H., Luo, Y., Etzerodt, A., Moestrup, S. K. & Romero-Ramos, M., 2023, In: npj Parkinson's Disease. 9, 1, 21 p., 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Synergistic effects of agonists and two-pore-domain potassium channels on secretory responses of human pancreatic duct cells Capan-1

    Sørensen, Christiane Elisabeth, Trauzold, A., Christensen, Nynne, Tawfik, D., Szczepanowski, M. & Novak, Ivana, 2023, In: Pflügers Archiv - European Journal of Physiology. 475, 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    The ABA/LANCL1/2 Hormone/Receptor System Controls Adipocyte Browning and Energy Expenditure

    Spinelli, S., Cossu, V., Passalacqua, M., Hansen, Jacob B., Guida, L., Magnone, M., Sambuceti, G., Marini, C., Sturla, L. & Zocchi, E., 2023, In: International Journal of Molecular Sciences. 24, 4, 27 p., 3489.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The enormous repetitive Antarctic krill genome reveals environmental adaptations and population insights

    Shao, C., Sun, S., Liu, K., Wang, J., Li, S., Liu, Q., Deagle, B. E., Seim, I., Biscontin, A., Wang, Q., Liu, X., Kawaguchi, S., Liu, Y., Jarman, S., Wang, Y., Wang, H. Y., Huang, G., Hu, J., Feng, B., De Pittà, C. & 29 others, Liu, S., Wang, R., Ma, K., Ying, Y., Sales, G., Sun, T., Wang, X., Zhang, Y., Zhao, Y., Pan, S., Hao, X., Wang, Y., Xu, J., Yue, B., Sun, Y., Zhang, H., Xu, M., Liu, Y., Jia, X., Zhu, J., Liu, S., Ruan, J., KU, thw266, Yang, H., Xu, X., Wang, J., Zhao, X., Meyer, B. & Fan, G., 2023, In: Cell. 186, 6, p. 1279-1294.e19 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

    Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

    Araya-Secchi, R., Bugge, K., Seiffert, P., Petry, A., Haxholm, G. W., Lindorff-Larsen, Kresten, Pedersen, Stine Helene Falsig, Arleth, Lise & Kragelund, Birthe Brandt, 2023, In: eLife. 12, 27 p., e84645.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Transient accumulation and bidirectional movement of KIF13B in primary cilia

    Juhl, A. D., Anvarian, Zeinab, Kuhns, S., Berges, J., Andersen, J. S., Wüstner, D. & Pedersen, Lotte Bang, 2023, In: Journal of Cell Science. 136, 5, 8 p., jcs259257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Variation of extrachromosomal circular DNA in cancer cell lines

    dos Santos, Carl Henrik Rung, Hansen, Lasse Bøllehuus, Rojas Triana, Monica, Johansen, A. Z., Perez-Moreno, Mirna & Regenberg, Birgitte, 2023, In: Computational and Structural Biotechnology Journal. 21, p. 4207-4214 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Xenobiotic Exposure and Migraine-Associated Signaling: A Multimethod Experimental Study Exploring Cellular Assays in Combination with Ex Vivo and In Vivo Mouse Models

    Rasmussen, Rikke Holm, Christensen, S. L., Callø, Kirstine, Nielsen, B. S., Rehfeld, A., Taylor-Clark, T. E., Haanes, Kristian Agmund, Taboureau, O., Audouze, K., Klærke, Dan Arne, Olesen, Jes & Kristensen, D. M., 2023, In: Environmental Health Perspectives. 131, 11, 14 p., 117003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    pXOOY: A dual-function vector for expression of membrane proteins in Saccharomyces cerevisiae and Xenopus laevis oocytes

    Vold, Victoria Amstrup, Glanville, S., Klærke, Dan Arne & Pedersen, Per Amstrup, 2023, In: PLoS ONE. 18, 2, 16 p., e0281868.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2022
  25. Published

    3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines

    Frikstad, K. M., Schink, K. O., Gilani, S., Pedersen, Lotte Bang & Patzke, S., 2022, In: Bio-protocol. 12, 6, 14 p., 4360.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Ex vivo Release of Calcitonin Gene-Related Peptide from the Trigeminovascular System in Rodents

    Rasmussen, R. H., Jansen-Olesen, I., Kristensen, D. M. & Christensen, S. L., 2022, In: Journal of Visualized Experiments. 183, 19 p., e63723.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    In Vitro Characterization of a Threonine-Ligated Molybdenyl-Sulfide Cluster as a Putative Cyanide Poisoning Antidote: Intracellular Distribution, Effects on Organic Osmolyte Homeostasis, and Induction of Cell Death

    Gretarsdottir, J. M., Lambert, Ian Henry, Stürup, Stefan & Suman, S. G., 2022, In: ACS Pharmacology and Translational Science. 5, 10, p. 907–918

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Setaphyes algarvensis sp. nov., the first description of an allomalorhagid mud dragon (Kinorhyncha: Allomalorhagida) from Portugal (Eastern Atlantic Ocean)

    Gonzalez-Casarrubios, A., Cepeda, D., Pardos, F., Neves, R. C. & Sanchez, N., 2022, In: European Journal of Taxonomy. 821, p. 150-165 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A Bacterial Genome and Culture Collection of Gut Microbial in Weanling Piglet

    Dong, B., Lin, X., Jing, X., Hu, T., Zhou, J., Chen, J., Xiao, L., Wang, B., Chen, Z., Liu, J., Hu, Y., Liu, G., Liu, S., Liu, J., Wei, W. & Zou, Y., 2022, In: Microbiology Spectrum. 10, 1, 13 p., e02417-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling

    Alphonse, N., Wanford, J. J., Voak, A. A., Gay, J., Venkhaya, S., Burroughs, O., Mathew, S., Lee, T., Evans, S. L., Zhao, W., Frowde, K., Alrehaili, A., Dickenson, R. E., Munk, M., Panina, S., Mahmood, I. F., Llorian, M., Stanifer, M. L., Boulant, S., Berchtold, M. W. & 4 others, Bergeron, J. R. C., Wack, A., Lesser, C. F. & Odendall, C., 2022, In: Cell. 185, 13, p. 2354-2369.e17

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    ATP signaling in pancreatic cancer: the P2X7 receptor

    Magni, Lara, Bouazzi, R., Christensen, Nynne, Tozzi, M., Poulsen, M., Johansen, J., Pless, Stephan & Novak, Ivana, 2022, In: Acta Physiologica. 236, S725, p. 661-661

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  32. Published

    Acid Adaptation Promotes TRPC1 Plasma Membrane Localization Leading to Pancreatic Ductal Adenocarcinoma Cell Proliferation and Migration through Ca2+ Entry and Interaction with PI3K/CaM

    Schnipper, J., Kouba, S., Hague, F., Girault, A., Telliez, M., Guenin, S., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: Cancers. 14, 19, 27 p., 4946.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Ameliorating effects of lifelong physical activity on healthy aging and mitochondrial function in human white adipose tissue

    Gudiksen, Anders, Qoqaj, A., Jørgensen, Stine Ringholm, Wojtaszewski, Jørgen F P, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2022, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 77, 6, p. 1101-1111 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs

    Alvarez-Dominguez, J. R., Winther, Sally, Hansen, Jacob B., Lodish, H. F. & Knoll, M., 2022, In: iScience. 25, 1, 25 p., 103680.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling

    Morthorst, Stine Kjær, Nielsen, C., Farinelli, P., Anvarian, Zeinab, Rasmussen, C. B. R., Serra-Marques, A., Grigoriev, I., Altelaar, M., Fürstenberg, N., Ludwig, A., Akhmanova, A., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2022, In: Journal of Cell Science. 135, 12, 10 p., jcs259471.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Beta2-agonist increases skeletal muscle interleukin 6 production and release in response to resistance exercise in men

    Hostrup, Morten, Knudsen, Jakob Grunnet, Maag Kristensen, C., Jessen, Søren Kaare, Pilegaard, Henriette & Bangsbo, Jens, 2022, In: Scandinavian Journal of Medicine & Science in Sports. 32, 7, p. 1099-1108 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cell transcriptomic atlas of the non-human primate Macaca fascicularis

    Han, L., Wei, X., Liu, C., Volpe, G., Zhuang, Z., Zou, X., Wang, Z., Pan, T., Yuan, Y., Zhang, X., Fan, P., Guo, P., Lai, Y., Lei, Y., Liu, X., Yu, F., Shangguan, S., Lai, G., Deng, Q., Liu, Y. & 57 others, Wu, L., Shi, Quan, Yu, H., Huang, Y., Cheng, M., Xu, J., Liu, Y., Wang, M., Wang, C., Zhang, Y., Xie, D., Yang, Y., Yu, Y., Zheng, H., Wei, Y., Huang, F., Lei, J., Huang, W., Zhu, Z., Lu, H., Wang, B., Wei, X., Chen, F., Yang, T., Du, W., Chen, J., Xu, S., An, J., Ward, C., Wang, Z., Pei, Z., Wong, C., Liu, X., Zhang, H., Liu, M., Qin, B., Schambach, A., Isern, J., Feng, L., Liu, Y., Guo, X., Liu, Z., Sun, Q., Maxwell, P. H., Barker, N., Muñoz-Cánoves, P., Gu, Y., Mulder, J., Uhlen, M., Tan, T., Liu, S., Yang, H., Wang, J., Hou, Y., Xu, X., Esteban, M. A. & Liu, L., 2022, In: Nature. 604, p. 723-731

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor

    La Cour, S. H., Juhler, K., Kogelman, L. J. A., Olesen, Jes, Klærke, Dan Arne, Kristensen, D. M. & Jansen-Olesen, I., 2022, In: Journal of Headache and Pain. 23, 12 p., 59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Could Experimental Inflammation Provide Better Understanding of Migraines?

    Reducha, Philip Victor, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: Cells. 11, 15, 17 p., 2444.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Differential expression of the three independent CaM genes coding for an identical protein: Potential relevance of distinct mRNA stability by different codon usage

    Munk, M., Villalobo, E., Villalobo, A. & Berchtold, Martin Werner, 2022, In: Cell Calcium. 107, 20 p., 102656.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Differential expression profiling of heat stressed tardigrades reveals major shift in the transcriptome

    Neves, R. C., Møbjerg, A., Kodama, M., Ramos Madrigal, Jazmin, Gilbert, M Thomas P & Møbjerg, Nadja, 2022, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 267, 7 p., 111169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Distribution of protoporphyrin IX in erythrocytes in a case of acquired erythropoietic protoporphyria

    Heerfordt, I. M., Fontenete, S., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 37, 3 p., 102629.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Dual action of the cannabinoid receptor 1 ligand arachidonyl-2′-chloroethylamide on calcitonin gene-related peptide release

    Christiansen, I. M., Edvinsson, J. C. A., Reducha, Philip Victor, Edvinsson, L. & Haanes, Kristian Agmund, 2022, In: Journal of Headache and Pain. 23, 11 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature

    Kohler, Katharina Theresa, Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René & Kim, Jiyoung, 2022, In: npj Breast Cancer. 8, 1, 12 p., 81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effect of perfluoroalkyl exposure in pregnancy and infancy on intrauterine and childhood growth and anthropometry. Sub study from COPSAC2010 birth cohort

    Sevelsted, A., Gürdeniz, G., Rago, D., Pedersen, C. T., Lasky-Su, J. A., Checa, A., Zhang, P., Wheelock, C. E., Normann, S. S., Kristensen, D. M., Rasmussen, Morten Arendt, Schullehner, J., Sdougkou, K., Martin, J. W., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2022, In: EBioMedicine. 83, 12 p., 104236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Entanglement in a qubit-qubit-tardigrade system

    Lee, K. S., Tan, Y. P., Nguyen, L. H., Budoyo, R. P., Park, K. H., Hufnagel, C., Yap, Y. S., Møbjerg, Nadja, Vedral, V., Paterek, T. & Dumke, R., 2022, In: New Journal of Physics. 24, 13 p., 123024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Extreme freeze-tolerance in cryophilic tardigrades relies on controlled ice formation but does not involve significant change in transcription: [Corrigendum]

    Møbjerg, A., Kodama, M., Ramos Madrigal, Jazmin, Neves, R. C., Jørgensen, Aslak, Schiøtt, M., Gilbert, M Thomas P & Møbjerg, Nadja, 2022, In: Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology. 271, 8 p., 111245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans

    Plomgaard, Peter Stendahl, Hansen, J. S., Townsend, L. K., Gudiksen, Anders, Secher, Niels H., Clemmesen, J. O., Støving, R. K., Goetze, Jens P. , Wright, D. C. & Pilegaard, Henriette, 2022, In: Frontiers in Endocrinology. 13, 1037948.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression

    Elingaard-Larsen, L. O., Rolver, M. G., Sørensen, E. E. & Pedersen, Stine Helene Falsig, 2022, From Malignant Transformation to Metastasis: Ion Transport in Tumor Biology. Stock, C. & Pardo, L. A. (eds.). Springer, p. 1-38 38 p. (Reviews of Physiology, Biochemistry and Pharmacology, Vol. 182).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  50. Published

    Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism

    Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Hypothesis: Metformin is a potential reproductive toxicant

    Tavlo, M., Skakkebæk, Niels Erik, Mathiesen, Elisabeth, Kristensen, D. M., Kjær, Kurt H., Andersson, A. & Lindahl-Jacobsen, R., 2022, In: Frontiers in Endocrinology. 13, 8 p., 1000872.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Isolation and Crystallization of the D156C Form of Optogenetic ChR2

    Zhang, L., Wang, Kaituo, Ning, S., Pedersen, Per Amstrup, Duelli, A. S. & Gourdon, Pontus Emanuel, 2022, In: Cells. 11, 5, 11 p., 895.

    Research output: Contribution to journalJournal articleResearchpeer-review

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