Des insulines pour orchestrer la croissance

Research output: Contribution to journal › Review › Research › peer-review

Standard

Des insulines pour orchestrer la croissance. / Boone, Emilie; Boulan, Laura; Andersen, Ditte S; Romero, Nuria; Léopold, Pierre; Colombani, Julien.

In: Medecine Sciences, Vol. 33, No. 6-7, 11.10.2017, p. 637-641.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Boone, E, Boulan, L, Andersen, DS, Romero, N, Léopold, P & Colombani, J 2017, 'Des insulines pour orchestrer la croissance', Medecine Sciences, vol. 33, no. 6-7, pp. 637-641. https://doi.org/10.1051/medsci/20173306021

APA

Boone, E., Boulan, L., Andersen, D. S., Romero, N., Léopold, P., & Colombani, J. (2017). Des insulines pour orchestrer la croissance. Medecine Sciences, 33(6-7), 637-641. https://doi.org/10.1051/medsci/20173306021

Vancouver

Boone E, Boulan L, Andersen DS, Romero N, Léopold P, Colombani J. Des insulines pour orchestrer la croissance. Medecine Sciences. 2017 Oct 11;33(6-7):637-641. https://doi.org/10.1051/medsci/20173306021

Author

Boone, Emilie ; Boulan, Laura ; Andersen, Ditte S ; Romero, Nuria ; Léopold, Pierre ; Colombani, Julien. / Des insulines pour orchestrer la croissance. In: Medecine Sciences. 2017 ; Vol. 33, No. 6-7. pp. 637-641.

Bibtex

@article{85a07acf0f7944acbb50852f0a4e5444,
title = "Des insulines pour orchestrer la croissance",
abstract = "Body size is an intrinsic property of living organisms that is intimately linked to the developmental program to produce fit individuals with proper proportions. Final size is the result of both genetic determinants and sophisticated mechanisms adapting size to available resources. Even though organs grow according to autonomous programs, some coordination mechanisms ensure that the different body parts adjust their growth with the rest of the body. In Drosophila, Dilp8, a hormone of the Insulin/Relaxin family is a key player in this inter-organs coordination and is required together with its receptor Lgr3 to limit developmental variability. Recently, the transcriptional co-activator Yki (homologue of YAP/TAZ factors in mammals) was shown to regulate dilp8 expression and contribute to the coordination of organ growth in Drosophila.",
keywords = "Animals, Drosophila Proteins/genetics, Drosophila melanogaster/genetics, Gene Expression Regulation, Developmental/drug effects, Growth and Development/drug effects, Humans, Insulins/genetics, Intercellular Signaling Peptides and Proteins/genetics, Signal Transduction/drug effects",
author = "Emilie Boone and Laura Boulan and Andersen, {Ditte S} and Nuria Romero and Pierre L{\'e}opold and Julien Colombani",
note = "{\textcopyright} 2017 m{\'e}decine/sciences – Inserm.",
year = "2017",
month = oct,
day = "11",
doi = "10.1051/medsci/20173306021",
language = "Fransk",
volume = "33",
pages = "637--641",
journal = "Medecine Sciences",
issn = "0767-0974",
publisher = "E D P Sciences",
number = "6-7",

}

RIS

TY - JOUR

T1 - Des insulines pour orchestrer la croissance

AU - Boone, Emilie

AU - Boulan, Laura

AU - Andersen, Ditte S

AU - Romero, Nuria

AU - Léopold, Pierre

AU - Colombani, Julien

N1 - © 2017 médecine/sciences – Inserm.

PY - 2017/10/11

Y1 - 2017/10/11

N2 - Body size is an intrinsic property of living organisms that is intimately linked to the developmental program to produce fit individuals with proper proportions. Final size is the result of both genetic determinants and sophisticated mechanisms adapting size to available resources. Even though organs grow according to autonomous programs, some coordination mechanisms ensure that the different body parts adjust their growth with the rest of the body. In Drosophila, Dilp8, a hormone of the Insulin/Relaxin family is a key player in this inter-organs coordination and is required together with its receptor Lgr3 to limit developmental variability. Recently, the transcriptional co-activator Yki (homologue of YAP/TAZ factors in mammals) was shown to regulate dilp8 expression and contribute to the coordination of organ growth in Drosophila.

AB - Body size is an intrinsic property of living organisms that is intimately linked to the developmental program to produce fit individuals with proper proportions. Final size is the result of both genetic determinants and sophisticated mechanisms adapting size to available resources. Even though organs grow according to autonomous programs, some coordination mechanisms ensure that the different body parts adjust their growth with the rest of the body. In Drosophila, Dilp8, a hormone of the Insulin/Relaxin family is a key player in this inter-organs coordination and is required together with its receptor Lgr3 to limit developmental variability. Recently, the transcriptional co-activator Yki (homologue of YAP/TAZ factors in mammals) was shown to regulate dilp8 expression and contribute to the coordination of organ growth in Drosophila.

KW - Animals

KW - Drosophila Proteins/genetics

KW - Drosophila melanogaster/genetics

KW - Gene Expression Regulation, Developmental/drug effects

KW - Growth and Development/drug effects

KW - Humans

KW - Insulins/genetics

KW - Intercellular Signaling Peptides and Proteins/genetics

KW - Signal Transduction/drug effects

U2 - 10.1051/medsci/20173306021

DO - 10.1051/medsci/20173306021

M3 - Review

C2 - 28990566

VL - 33

SP - 637

EP - 641

JO - Medecine Sciences

JF - Medecine Sciences

SN - 0767-0974

IS - 6-7

ER -

ID: 213243376