Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones. / Carstensen, Klaus; McFarlane, Ian D.; Rinehart, Kenneth L.; Hudman, Diane; Sun, Furong; Grimmelikhuijzen, Cornelis J.P.

In: Peptides, Vol. 14, No. 2, 1993, p. 131-135.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Carstensen, K, McFarlane, ID, Rinehart, KL, Hudman, D, Sun, F & Grimmelikhuijzen, CJP 1993, 'Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones', Peptides, vol. 14, no. 2, pp. 131-135. https://doi.org/10.1016/0196-9781(93)90020-H

APA

Carstensen, K., McFarlane, I. D., Rinehart, K. L., Hudman, D., Sun, F., & Grimmelikhuijzen, C. J. P. (1993). Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones. Peptides, 14(2), 131-135. https://doi.org/10.1016/0196-9781(93)90020-H

Vancouver

Carstensen K, McFarlane ID, Rinehart KL, Hudman D, Sun F, Grimmelikhuijzen CJP. Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones. Peptides. 1993;14(2):131-135. https://doi.org/10.1016/0196-9781(93)90020-H

Author

Carstensen, Klaus ; McFarlane, Ian D. ; Rinehart, Kenneth L. ; Hudman, Diane ; Sun, Furong ; Grimmelikhuijzen, Cornelis J.P. / Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones. In: Peptides. 1993 ; Vol. 14, No. 2. pp. 131-135.

Bibtex

@article{f633c5bb509f42c394ea826237c02c5d,
title = "Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones",
abstract = "Using a radioimmunoassay against the C-terminal sequence Arg-Pro-NH2 (RPamide) we have isolated the neuropeptide <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II) from extracts of the sea anemone Anthopleura elegantissima. Addition of low concentrations of Antho-RPamide II to a tentacle preparation of sea anemones inhibited the spontaneous, rhythmic contractions, suggesting that the peptide is a neurotransmitter or neuromodulator.",
keywords = "Coelenterate, Mass spectrometry, Neurohormone, Neurotransmitter, Peptide structure",
author = "Klaus Carstensen and McFarlane, {Ian D.} and Rinehart, {Kenneth L.} and Diane Hudman and Furong Sun and Grimmelikhuijzen, {Cornelis J.P.}",
note = "Funding Information: We thank Susanne Raabe and Dagmar Boshold for typing the manuscript, and the Bundesministerium f'dr Forschung und Technologie, the Deutsche Forschungsgemeinschafi (Gr 762/7-3), Fonds der Chemischen lndustrie (to C.J.P.G.), NATO (Collaborative Research Grant to C.J.P.G.), Ciba-Geigy (Award for Cooperation in Europe to I.D.M.), and the National Institute of General Medical Sciences (GM 27029, to K.L.R.) for financial support. A part of this article is based on a doctoral study by K.C. in the Faculty of Biology, University of Hamburg.",
year = "1993",
doi = "10.1016/0196-9781(93)90020-H",
language = "English",
volume = "14",
pages = "131--135",
journal = "Peptides",
issn = "0196-9781",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Isolation of <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II), a novel, biologically active neuropeptide from sea anemones

AU - Carstensen, Klaus

AU - McFarlane, Ian D.

AU - Rinehart, Kenneth L.

AU - Hudman, Diane

AU - Sun, Furong

AU - Grimmelikhuijzen, Cornelis J.P.

N1 - Funding Information: We thank Susanne Raabe and Dagmar Boshold for typing the manuscript, and the Bundesministerium f'dr Forschung und Technologie, the Deutsche Forschungsgemeinschafi (Gr 762/7-3), Fonds der Chemischen lndustrie (to C.J.P.G.), NATO (Collaborative Research Grant to C.J.P.G.), Ciba-Geigy (Award for Cooperation in Europe to I.D.M.), and the National Institute of General Medical Sciences (GM 27029, to K.L.R.) for financial support. A part of this article is based on a doctoral study by K.C. in the Faculty of Biology, University of Hamburg.

PY - 1993

Y1 - 1993

N2 - Using a radioimmunoassay against the C-terminal sequence Arg-Pro-NH2 (RPamide) we have isolated the neuropeptide <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II) from extracts of the sea anemone Anthopleura elegantissima. Addition of low concentrations of Antho-RPamide II to a tentacle preparation of sea anemones inhibited the spontaneous, rhythmic contractions, suggesting that the peptide is a neurotransmitter or neuromodulator.

AB - Using a radioimmunoassay against the C-terminal sequence Arg-Pro-NH2 (RPamide) we have isolated the neuropeptide <Glu-Asn-Phe-His-Leu-Arg-Pro-NH2 (Antho-RPamide II) from extracts of the sea anemone Anthopleura elegantissima. Addition of low concentrations of Antho-RPamide II to a tentacle preparation of sea anemones inhibited the spontaneous, rhythmic contractions, suggesting that the peptide is a neurotransmitter or neuromodulator.

KW - Coelenterate

KW - Mass spectrometry

KW - Neurohormone

KW - Neurotransmitter

KW - Peptide structure

UR - http://www.scopus.com/inward/record.url?scp=0027394813&partnerID=8YFLogxK

U2 - 10.1016/0196-9781(93)90020-H

DO - 10.1016/0196-9781(93)90020-H

M3 - Journal article

C2 - 8483793

AN - SCOPUS:0027394813

VL - 14

SP - 131

EP - 135

JO - Peptides

JF - Peptides

SN - 0196-9781

IS - 2

ER -

ID: 370739696