Functional Genomics

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  1. 2019
  2. Published

    Efflux-Pump Upregulation: From Tolerance to High-level Antibiotic Resistance?

    Frimodt-Møller, Jakob & Løbner-Olesen, Anders, 2019, In: Trends in Microbiology. 27, 4, p. 291-293

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Comparative genomics for non-O1/O139 Vibrio cholerae isolates recovered from the Yangtze River Estuary versus V. cholerae representative isolates from serogroup O1

    Gong, L., Yu, P., Zheng, H., Gu, W., He, W., Tang, Y., Wang, Y., Dong, Y., Peng, Xu, She, Q., Xie, L. & Chen, L., 2019, In: Molecular Genetics and Genomics. 294, 2, p. 417-430

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system

    Guo, T., Zheng, F., Zeng, Z., Yang, Y., Li, Q., She, Q. & Han, W., 2019, In: RNA Biology. 16, 10, p. 1513-1520

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Investigation of the Sulfolobus islandicus III-B Cmr-α CRISPR-Cas system and SMV1 anti-CRISPR activity

    Guo, T., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  6. Published

    Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus

    Guo, T., Han, W. & She, Q., 2019, In: RNA Biology. 16, 4, p. 549-556 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Comparative activity of ceftriaxone, ciprofloxacin and gentamicin as a function of bacterial growth rate probed by Escherichia coli chromosome replication in the mouse peritonitis model

    Haugan, M. S., Løbner-Olesen, Anders & Frimodt-Møller, N., 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 13 p., e-02133-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Examination of bacterial growth rate during host infection and its importance for antimicrobial treatment

    Haugan, M. S., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  9. Published

    Growth Rate of Escherichia coli During Human Urinary Tract Infection: Implications for Antibiotic Effect

    Haugan, M. S., Hertz, F. B., Charbon, Godefroid, Sahin, B., Løbner-Olesen, Anders & Frimodt-Møller, N., 2019, In: Antibiotics. 8, 3, 12 p., 92.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Synthesis of Shld Derivatives, Their Binding to the Destabilizing Domain, and Influence on Protein Accumulation in Transgenic Plants

    Jørgensen, F. P., Madsen, D., Meldal, Morten Peter, Olsen, J. V., Petersen, Morten, Granhøj, J. & Bols, Mikael, 2019, In: Journal of Medicinal Chemistry. 62, 10, p. 5191-5216 26 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Esc2 promotes telomere stability in response to DNA replication stress

    Jørgensen, S. W., Liberti, S. E., Larsen, N. B., Lisby, Michael, Mankouri, H. W. & Hickson, Ian David, 2019, In: Nucleic Acids Research. 47, 9, p. 4597-4611 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Guidelines for DNA recombination and repair studies: cellular assays of DNA repair pathways

    Klein, H. L., Bacinskaja, G., Che, J., Cheblal, A., Elango, R., Epshtein, A., Fitzgerald, D. M., Gómez-González, B., Khan, S. R., Kumar, S., Leland, B. A., Marie, L., Mei, Q., Miné-Hattab, J., Piotrowska, A., Polleys, E. J., Putnam, C. D., Radchenko, E. A., Saada, A. A., Sakofsky, C. J. & 28 others, Shim, E. Y., Stracy, M., Xia, J., Yan, Z., Yin, Y., Aguilera, A., Argueso, J. L., Freudenreich, C. H., Gasser, S. M., Gordenin, D. A., Haber, J. E., Ira, G., Jinks-Robertson, S., King, M. C., Kolodner, R. D., Kuzminov, A., Lambert, S. A. E., Lee, S. E., Miller, K. M., Mirkin, S. M., Petes, T. D., Rosenberg, S. M., Rothstein, R., Symington, L. S., Zawadzki, P., Kim, N., Lisby, Michael & Malkova, A., 2019, In: Microbial Cell Factories. 6, 1, p. 1-64

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    A Novel Fluorescence-Based Screen for Inhibitors of the Initiation of DNA Replication in Bacteria

    Klitgaard, R. N. & Løbner-Olesen, Anders, 2019, In: Current Drug Discovery Technologies. 16, 3, p. 272-277

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Phylogenomics Provides New Insights into Gains and Losses of Selenoproteins among Archaeplastida

    Liang, H., Wei, T., Xu, Y., Li, L., Sahu, S. K., Wang, H., Li, H., Fu, X., Zhang, G., Melkonian, M., Liu, X., Wang, S. & Liu, Huan, 2019, In: International Journal of Molecular Sciences (Online). 20, 12, 14 p., 3020.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Schinus terebinthifolia leaf lectin (SteLL) has anti-infective action and modulates the response of Staphylococcus aureus-infected macrophages

    Lima, I. M. D. S. F., Zagmignan, A., Santos, D. M., Maia, H. S., Silva, L. D. S., Cutrim, B. D. S., Vieira, S. L., Filho, C. M. B., de Sousa, E. M., Napoleão, T. H., Krogfelt, K. A., Løbner-Olesen, Anders, Paiva, P. M. G. & da Silva, L. C. N., 2019, In: Scientific Reports. 9, 14 p., 18159.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A novel type III CRISPR-Cas system in Lactobacilli: Molecular mechanisms and its application potential

    Lin, Jinzhong, 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  17. Published

    Structure-Activity Study of an All-D Antimicrobial Octapeptide D2D

    Lone, A., Thomsen, T. T., Nielsen, J. E., Thulstrup, Peter Waaben, Klitgaard, R. N., Løbner-Olesen, Anders, Lund, R., Jenssen, H. & Hansen, Paul Robert, 2019, In: Molecules. 24, 24, 17 p., 4571.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Regulation of Ribonucleotide Reductase and Screening for Species-Specific Inhibitors in Fission Yeast

    Løvschal, K. V., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  19. Published

    Predicted highly derived class 1 CRISPR-Cas system in Haloarchaea containing diverged Cas5 and Cas7 homologs but no CRISPR array

    Makarova, K. S., Karamycheva, S., Shah, S. A., Vestergaard, G. A., Garrett, Roger Antony & Koonin, E. V., 2019, In: FEMS Microbiology Letters. 366, 7, 5 p., fnz079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain

    Manav, M. C., Turnbull, K. J., Jurėnas, D., Garcia-Pino, A., Gerdes, K. & Brodersen, D. E., 2019, In: Structure. 27, 11, p. 1675-1685, e1-e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

    Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, Guillermo, 2019, In: Nature Communications. 10, 14 p., 4302.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase

    Nielsen, S. V., Turnbull, K. J., Roghanian, Mohammad, Bærentsen, R., Semanjski, M., Brodersen, D. E., Macek, B. & Gerdes, K., 2019, In: mBio. 10, 3, 16 p., e-01138-19.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A seed motif for target RNA capture enables efficient immune defence by a type III-B CRISPR-Cas system

    Pan, S., Li, Q., Deng, Ling, Jiang, S., Jin, X., Peng, N., Liang, Y., She, Q. & Li, Y., 2019, In: RNA Biology. 16, 9, p. 1166-1178

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Stable maintenance of the rudivirus SIRV3 in a carrier state in Sulfolobus islandicus despite activation of the CRISPR-Cas immune response by a second virus SMV1

    Papathanasiou, P., Erdmann, S., Leon-Sobrino, C., Sharma, K., Urlaub, H., Garrett, Roger Antony & Peng, Xu, 2019, In: RNA Biology. 16, 4, p. 557-565

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The PCNA interaction motifs revisited: thinking outside the PIP-box

    Prestel, Andreas, Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter & Kragelund, Birthe Brandt, 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex

    Qian, H., Yu, H., Li, P., Zhu, E., Yao, Q., Tai, C., Deng, Z., Gerdes, K., He, X., Gan, J. & Ou, H., 2019, In: Nucleic Acids Research. 47, 14, p. 7690-7702

    Research output: Contribution to journal › Journal article › Research › peer-review

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