Functional Genomics

  1. 2017
  2. Published

    Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication

    Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Regulation of telomere metabolism by the RNA processing protein Xrn1

    Cesena, D., Cassani, C., Rizzo, E., Lisby, Michael, Bonetti, D. & Longhese, M. P., 20 Apr 2017, In: Nucleic Acids Research. 45, 7, p. 3860-3874 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Transcription-replication conflicts at chromosomal fragile sites—consequences in M phase and beyond

    Østergaard, Vibe Hallundbæk & Lisby, Michael, Mar 2017, In: Chromosoma. 126, 2, p. 213-222 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Phosphatidylserine stimulates ceramide 1-phosphate (C1P) intermembrane transfer by C1P transfer proteins

    Zhai, X., Gao, Y., Mishra, S. K., Simanshu, D. K., Boldyrev, I. A., Benson, L. M., Bergen III, H. R., Malinina, L., Mundy, J., Molotkovsky, J. G., Patel, D. J. & Brown, R. E., 10 Feb 2017, In: Journal of Biological Chemistry. 292, 6, p. 2531-2541 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast

    Toteva, T., Mason, B., Kanoh, Y., Brøgger, P., Green, D., Hansen, J. V., Masai, H. & Thon, Genevieve, 31 Jan 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 1093-1098 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Re-wiring of energy metabolism promotes viability during hyperreplication stress in E. coli

    Charbon, Godefroid, Campion, C., Chan, S. H. J., Bjørn, L., Weimann, A., da Silva, L. C. N., Jensen, P. R. & Løbner-Olesen, Anders, 27 Jan 2017, In: PLoS Genetics. 13, 1, 26 p., e1006590.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    3Rs tightly intertwined to maintain genome stability

    Lisby, Michael & Mortensen, U. H., Jan 2017, In: FEMS Yeast Research. 17, 1, 2 p., fox003.

    Research output: Contribution to journalEditorialResearch

  9. Published

    Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains

    Sebesta, M., Urulangodi, M., Stefanovie, B., Szakal, B., Pacesa, M., Lisby, Michael, Branzei, D. & Krejci, L., Jan 2017, In: Nucleic Acids Research. 45, 1, p. 215-230 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1

    Poulsen, E. G., Kampmeyer, Caroline, Kriegenburg, F., Johansen, Jens Vilstrup, Hofmann, K., Holmberg, Christian & Hartmann-Petersen, Rasmus, Jan 2017, In: Cell Stress & Chaperones. 22, 1, p. 143-154 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction

    Han, W., Li, Y., Deng, Ling, Feng, M., Peng, W., Hallstrøm, S., Zhang, J., Peng, N., Liang, Y. X., White, M. F. & She, Q., 2017, In: Nucleic Acids Research. 45, 4, p. 1983–1993 11 p., gkw1274.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Autophagy is required for gamete differentiation in the moss Physcomitrella patens

    Sanchez-Vera, V., Kenchappa, C. S., Landberg, K., Bressendorff, Simon, Schwarzbach, S., Martin, T., Mundy, J., Petersen, Morten, Thelander, M. & Sundberg, E., 2017, In: Autophagy. 13, 11, p. 1939-1951 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    CRISPR History: Discovery, Characterization, and Prosperity

    Han, W. & She, Q., 2017, CRISPR in Animals and Animal Models. Torres-Ruiz, R. & Rodriguez-Perales, S. (eds.). Elsevier, p. 1-21 20 p. (Progress in Molecular Biology and Translational Science, Vol. 152).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  14. Published

    CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b

    He, F., Vestergaard, G. A., Peng, W., She, Q. & Peng, Xu, 2017, In: Nucleic Acids Research. 45, 4, p. 1902-1913 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Chitin and stress induced protein kinase activation

    Kenchappa, C. S., Azevedo da Silva, R., Bressendorff, Simon, Stanimirovic, S., Olsen, J. V., Petersen, Morten & Mundy, J., 2017, Plant pattern recognition receptors: methods and protocols. Shan, L. & He, P. (eds.). Springer, p. 185-194 10 p. (Methods in Molecular Biology, Vol. 1578).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Chitin-induced responses in the moss Physcomitrella patens

    Bressendorff, Simon, Rasmussen, M. W., Petersen, Morten & Mundy, J., 2017, Plant pattern recognition receptors: methods and protocols. Shan, L. & He, P. (eds.). Springer, p. 317-324 8 p. (Methods in Molecular Biology, Vol. 1578).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    Control of bacterial chromosome replication by non-coding regions outside the origin

    Frimodt-Møller, Jakob, Charbon, Godefroid & Løbner-Olesen, Anders, 2017, In: Current Genetics. 63, 4, p. 607-611 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Coupling transcriptional activation of CRISPR–Cas system and DNA repair genes by Csa3a in Sulfolobus islandicus

    Liu, T., Liu, Z., Ye, Q., Pan, S., Wang, X., Li, Y., Peng, W., Liang, Y., She, Q. & Peng, N., 2017, In: Nucleic Acids Research. 45, 15, p. 8978–8992 15 p., gkx612.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    DNA damage repair in Archaea

    She, Q., Feng, X. & Han, W., 2017, Biocommunication of Archaea. Witzany, G. (ed.). Springer, p. 305-318 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    Determination of protein turnover in E. coli cells during exit from persistence

    Semanjski, M., Germain-Maisonneuve, E., Gerdes, K. & Macek, B., 2017, In: F A S E B Journal. 31, S1, 1 p., 915.2.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. Published

    Discrete structural dynamics of pseudo-palindromic motifs control DNA binding of bacterial toxin-antitoxin complexes

    Brodersen, D. E., Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A. & Pedersen, C. N. S., 2017, In: F A S E B Journal. 31, S1, 1 p., 777.2.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    Elucidating the roles of MAP kinases in the moss Physcomitrella patens

    Stanimirovic, S., 2017, Department of Biology, Faculty of Science, University of Copenhagen. 230 p.

    Research output: Book/ReportPh.D. thesisResearch

  23. Published

    Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: A systematic analysis for the Global Burden of Disease Study 2016

    Wang, H., Abajobir, A. A., Abate, K. H., Abbafati, C., Abbas, K. M., Abd-Allah, F., Abera, S. F., Abraha, H. N., Abu-Raddad, L. J., Abu-Rmeileh, N. M. E., Adedeji, I. A., Adedoyin, R. A., Adetifa, I. M. O., Adetokunboh, O., Afshin, A., Aggarwal, R., Agrawal, A., Agrawal, S., Ahmad Kiadaliri, A., Ahmed, M. B. & 31 others, Aichour, A. N., Aichour, I., Aichour, M. T. E., Aiyar, S., Akanda, A. S., Akinyemiju, T. F., Akseer, N., Al-Eyadhy, A., Al Lami, F. H., Alabed, S., Alahdab, F., Al-Aly, Z., Alam, K., Alam, N., Alasfoor, D., Aldridge, R. W., Alene, K. A., Bjerregaard, P., Christensen, H., De Courten, B., Havmoeller, R., He, F., Iburg, K. M., Larsson, A., McGrath, J. J., Mengistie, M. A., Singh, Prashant, Sobngwi, E., Truelsen, Thomas Clement, Wang, Y. & GBD 2016 Mortality Collaborators, G. 2. M. C., 2017, In: The Lancet. 390, 10100, p. 1084-1150 67 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Matching NLR immune receptors to autoimmunity in camta3 mutants using antimorphic NLR alleles

    Lolle, S., Greeff, M. C., Petersen, K., Roux, M. E., Jensen, M. K., Bressendorff, Simon, Rodriguez, Eleazar, Sømark, K., Mundy, J. & Petersen, Morten, 2017, In: Cell Host & Microbe. 21, 4, p. 518-529 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB

    Fazli, M., Rybtke, Morten Levin, Steiner, E., Weidel, E., Berthelsen, J., Groizeleau, J. D. D., Bin, W., Zhi, B. Z., Yaming, Z., Kaever, V., Givskov, Michael, Hartmann, R. W., Eberl, L. & Tolker-Nielsen, Tim, 2017, In: MicrobiologyOpen. 6, 4, 13 p., e00480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The role of the Saccharomyces cerevisiae Rdh54 DNA translocase at kinetochores

    Bacinskaja, G., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  27. Published

    Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding

    Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A., Pedersen, C. N. S. & Brodersen, D. E., 2017, In: Nucleic Acids Research. 45, 5, p. 2875-2886 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Type III CRISPR/Cas system: introduction and its application for genetic manipulations

    Liu, T., Pan, S., Li, Y., Peng, N. & She, Q., 2017, The CRISPR/Cas system: emerging technology and application. Jamal, M. (ed.). Caister Academic Press, p. 1-13 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  29. Published

    Uncovering the roots of paranoid suicidal plants

    Lolle, S., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  30. 2016
  31. Published

    Back to the roots: deep view into the evolutionary history of ADP-ribosylation opened by the DNA-targeting toxin-antitoxin module DarTG

    Harms, A. & Gerdes, K., 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1020-1021 2 p.

    Research output: Contribution to journalComment/debateResearch

  32. Published

    Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Encoded mRNases

    Tian, C., Roghanian, Mohammad, Jørgensen, M. G., Sneppen, Kim, Sørensen, Michael Askvad, Gerdes, K. & Mitarai, Namiko, Jul 2016, In: Journal of Bacteriology. 198, 14, p. 1918-1926

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Life cycle characterization of Sulfolobus monocaudavirus 1, an extremophilic spindle-shaped virus with extracellular tail development

    Uldahl, K. B., Jensen, S. B., Bhoobalan, Yuvaraj, Martinez Alvarez, Laura, Papathanasiou, P. & Peng, Xu, Jun 2016, In: Journal of Virology. 90, 12, p. 5693-5699 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Configuration-dependent Presentation of Multivalent IL-15: IL-15Rα enhances the antigen-specific T cell response and anti-tumor immunity

    Hong, E., Usiskin, I. M., Bergamaschi, C., Hanlon, D. J., Edelson, R. L., Justesen, S., Pavlakis, G. N., Flavell, R. A. & Fahmy, T. M., 22 Apr 2016, In: Journal of Biological Chemistry. 291, 17, p. 8931-8950 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    "Population structure of drug-susceptible, -resistant and ESBL-producing Escherichia coli from community-acquired urinary tract infections"

    Hertz, F. B., Nielsen, J. B., Schønning, Kristian, Littauer, P., Knudsen, J. D., Løbner-Olesen, Anders & Frimodt-Møller, N., 11 Apr 2016, In: BMC Microbiology. 16, 6 p., 63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The role of HERC2 and RNF8 ubiquitin E3 ligases in the promotion of translesion DNA synthesis in the chicken DT40 cell line

    Mohiuddin, M., Kobayashi, S., Keka, I. S., Guilbaud, G., Sale, J., Narita, Takeo, Abdel-Aziz, H. I., Wang, X., Ogawa, S., Sasanuma, H., Chiu, R., Østergaard, Vibe Hallundbæk, Lisby, Michael & Takeda, S., Apr 2016, In: DNA Repair. 40, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Salmonella Typhimurium undergoes distinct genetic adaption during chronic infections of mice

    Søndberg, E. & Jelsbak, L., 2016, In: BMC Microbiology. 16, 11 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Adipokinetic hormones and their G protein-coupled receptors emerged in Lophotrochozoa

    Li, S., Hauser, Frank, Skadborg, S. K., Nielsen, S. V., Kirketerp-Møller, N. & Grimmelikhuijzen, Cornelis (Cok), 2016, In: Scientific Reports. 6, 13 p., 32789.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Alarmone (p)ppGpp regulates the transition from pathogenicity to mutualism in Photorhabdus luminescens

    Skjerning, R. B., Roghanian, Mohammad, Gerdes, K. & Clarke, D. J., 2016, In: Molecular Microbiology. 100, 4, p. 735-747 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

    Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, Henrik, Frimodt-Møller, N., Løbner-Olesen, Anders & Hansen, Paul Robert, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    An innate immunity pathway in the moss Physcomitrella patens

    Bressendorff, Simon, Azevedo da Silva, R., Kenchappa, C. S., Ponce de León, I., Olsen, J. V., Rasmussen, M. W., Erbs, G., Newman, Mari-Anne, Petersen, Morten & Mundy, J., 2016, In: The Plant Cell. 28, 6, p. 1328-1342 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Archaeal physiology: the secrets of termination

    Garrett, Roger Antony, 2016, In: Nature Microbiology. 1, 2 p., 16159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Barley plants over-expressing the NAC transcription factor gene HvNAC005 show stunting and delay in development combined with early senescence

    Christiansen, M. W., Matthewman, C., Podzimska-Sroka, D. A., O'Shea, Charlotte, Lindemose, Søren, Møllegaard, Niels Erik, Holme, I. B., Hebelstrup, K., Skriver, Karen & Gregersen, P. L., 2016, In: Journal of Experimental Botany. 67, 17, p. 5259-5273 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Cdc14 phosphatase: warning, no delay allowed for chromosome segregation!

    Machín, F., Quevedo Rodriguez, O., Ramos-Pérez, C. & García-Luis, J., 2016, In: Current Genetics. 62, 1, p. 7-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Characterizing leader sequences of CRISPR loci

    Alkhnbashi, O., Shah, S. A., Garrett, Roger Antony, Saunders, S. J., Costa, F. & Backofen, R., 2016, In: Bioinformatics. 32, 17, p. i576-i585 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Construction and characterization of three protein-targeting expression system in Lactobacillus casei

    Lin, J., Zou, Y., Ma, C., Liang, Y., Ge, X., Chen, Z. & She, Q., 2016, In: F E M S Microbiology Letters. 363, 7, 8 p.

    Research output: Contribution to journalLetterResearchpeer-review

  47. Published

    DNA replication control is linked to genomic positioning of control regions in Escherichia coli

    Frimodt-Møller, Jakob, Charbon, Godefroid, Krogfelt, K. A. & Løbner-Olesen, Anders, 2016, In: P L o S Genetics. 12, 9, 27 p., e1006286.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Discovery and characterization of a thermostable and highly halotolerant GH5 cellulase from an Icelandic hot spring isolate

    Zarafeta, D., Kissas, D., Sayer, C., Islin, S. R., Ladoukakis, E., Isupov, M. N., Chatziioannou, A., Peng, Xu, Littlechild, J. A., Skretas, G. & Kolisis, F. N., 2016, In: P L o S One. 11, 1, 18 p., e0146454.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Diverse CRISPR-Cas responses and dramatic cellular DNA changes and cell death in pKEF9-conjugated Sulfolobus species

    Guannan, L., She, Q. & Garrett, Roger Antony, 2016, In: Nucleic Acids Research. 44, 9, p. 4233-4242 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Diverse gene functions in a soil mobilome

    Luo, W., Xu, Z., Riber, Leise, Hansen, Lars Hestbjerg & Sørensen, Søren Johannes, 2016, In: Soil Biology & Biochemistry. 101, p. 175-183 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Epidemiological factors associated with ESBL- and non ESBL-producing E. coli causing urinary tract infection in general practice

    Hertz, F. B., Schønning, K., Rasmussen, S. C., Littauer, P., Knudsen, J. D., Løbner-Olesen, Anders & Frimodt-Møller, N., 2016, In: Infectious Diseases. 48, 3, p. 241-245 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    EstDZ3: a new esterolytic enzyme exhibiting remarkable thermostability

    Zarafeta, D., Szabo, Z., Moschidi, D., Phan, Safir Hien, Chrysina, E. D., Peng, Xu, Ingham, C. J., Kolisis, F. N. & Skretas, G., 2016, In: Frontiers in Microbiology. 7, 14 p., 1779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Guidelines for the use and interpretation of assays for monitoring autophagy: 3rd edition

    Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M. & 2,447 others, Ait-Si-Ali, S., Akematsu, T., Akporiaye, E. T., Al-Rubeai, M., Albaiceta, G. M., Albanese, C., Albani, D., Albert, M. L., Aldudo, J., Algül, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E. S., Alonso, C., Altan-Bonnet, N., Altieri, D. C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A. O., Amessou, M., Amon, A., An, Z., Anania, F. A., Andersen, S. U., Andley, U. P., Andreadi, C. K., Andrieu-Abadie, N., Anel, A., Ann, D. K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A. R., Armstrong, J. L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S. S., Atkin, J. D., Attardi, L. D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M. L., Avrahami, L., Awale, S., Azad, N., Bachetti, T., Backer, J. M., Bae, D., Bae, J., Bae, O., Bae, S. H., Baehrecke, E. H., Baek, S., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bailly, Y., Balaji, K. N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Bánhegyi, G., Bao, H., Barbeau, B., Barrachina, M. D., Barreiro, E., Bartel, B., Bartolomé, A., Bassham, D. C., Bassi, M. T., Bast, R. C., Basu, A., Batista, M. T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B. L., Bayer, K. U., Beale, R., Beaulieu, J., Beck, G. R., Becker, C., Beckham, J. D., Bédard, P., Bednarski, P. J., Begley, T. J., Behl, C., Behrends, C., Behrens, G. M., Behrns, K. E., Bejarano, E., Belaid, A., Belleudi, F., Bénard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A. S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S. K., Biagosch, C., Bianchi, M. W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S. W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G. A., Blomhoff, H. K., Boada-Romero, E., Böckler, S., Boes, M., Boesze-Battaglia, K., Boise, L. H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L. M., Botti, J., Bou, G., Bouché, M., Bouchecareilh, M., Boucher, M., Boulton, M. E., Bouret, S. G., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N., Braga, V. M., Brancolini, C., Braus, G. H., Bravo-San Pedro, J. M., Brennan, L. A., Bresnick, E. H., Brest, P., Bridges, D., Bringer, M., Brini, M., Brito, G. C., Brodin, B., Brookes, P. S., Brown, E. J., Brown, K., Broxmeyer, H. E., Bruhat, A., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bryson-Richardson, R. J., Buch, S., Buchan, A. M., Budak, H., Bulavin, D. V., Bultman, S. J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R. E., Burmeister, M., Bütikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G. R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A. B., Caraglia, M., Cardinali, C., Cardoso, S. M., Carew, J. S., Carleton, L. A., Carlin, C. R., Carloni, S., Carlsson, S. R., Carmona-Gutierrez, D., Carneiro, L. A., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A. I., Ceña, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H., Chagin, A. S., Chai, C., Chakrabarti, G., Chamilos, G., Chan, E. Y., Chan, M. T., Chandra, D., Chandra, P., Chang, C., Chang, R. C., Chang, T. Y., Chatham, J. C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M. E., Cheluvappa, R., Chen, C., Chen, G., Chen, G., Chen, G., Chen, H., Chen, J. W., Chen, J., Chen, M., Chen, M., Chen, P., Chen, Q., Chen, Q., Chen, S., Chen, S., Chen, S. S., Chen, W., Chen, W., Chen, W. Q., Chen, W., Chen, X., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Z., Chen, Z., Cheng, A., Cheng, C. H., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C. H. A., Chevet, E., Chi, H. C., Chi, S., Chiacchiera, F., Chiang, H., Chiarelli, R., Chiariello, M., Chieppa, M., Chin, L., Chiong, M., Chiu, G. N., Cho, D., Cho, S., Cho, W. C., Cho, Y., Cho, Y., Choi, A. M., Choi, E., Choi, E., Choi, J., Choi, M. 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S., Zhang, D. D., Zhang, F., Zhang, G., Zhang, G., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, J., Zhang, J., Zhang, J., Zhang, J., Zhang, J., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, M., Zhang, X., Zhang, X. D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhao, M., Zhao, W., Zhao, X., Zhao, Y. G., Zhao, Y., Zhao, Y., Zhao, Y., Zhao, Z., Zhao, Z. J., Zheng, D., Zheng, X., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, G., Zhou, G., Zhou, H., Zhou, S., Zhou, X., Zhu, H., Zhu, H., Zhu, W., Zhu, W., Zhu, X., Zhu, Y., Zhuang, S., Zhuang, X., Ziparo, E., Zois, C. E., Zoladek, T., Zong, W., Zorzano, A. & Zughaier, S. M., 2016, In: Autophagy. 12, 1, p. 1-222 222 p.

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    Harnessing type I and type III CRISPR-Cas systems for genome editing

    Li, Y., Pan, S., Zhang, Y., Ren, M., Feng, M., Peng, N., Chen, L., Liang, Y. X. & She, Q., 2016, In: Nucleic Acids Research. 44, 4, 12 p., e34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Hypothesis: type I toxin - antitoxin genes enter the persistence field-a feedback mechanism explaining membrane homoeostasis

    Gerdes, K., 2016, In: Royal Society of London. Philosophical Transactions B. Biological Sciences. 371, 1707, 9 p., 20160189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Isolation and characterization of the first Xylanolytic hyperthermophilic euryarchaeon Thermococcus sp strain 2319x1 and its unusual multidomain glycosidase

    Gavrilov, S. N., Stracke, C., Jensen, K., Menzel, P., Kallnik, V., Slesarev, A., Sokolova, T., Zayulina, K., Bräsen, C., Bonch-Osmolovskaya, E. A., Peng, Xu, Kublanov, I. V. & Siebers, B., 2016, In: Frontiers in Microbiology. 7, 17 p., 552.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Isolation of a novel protein, P12-from adult Drosophila melanogaster that inhibits deoxyribonucleoside and protein kinase activities and activates 3'-5'-exonuclease activity

    Christiansen, L. S., Zanten, G. V., Berenstein, D., Lauridsen, M., Kjærulff, S., Søndergaard, Leif & Munch-Petersen, B., 2016, In: Nucleosides, Nucleotides and Nucleic Acids. 35, 10-12, p. 699-706 8 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  58. Published

    MYB75 phosphorylation by MPK4 is required for light-induced anthocyanin accumulation in arabidopsis

    Li, S., Wang, W., Gao, J., Yin, K., Wang, R., Wang, C., Petersen, Morten, Mundy, J. & Qiu, J., 2016, In: The Plant Cell. 28, 11, p. 2866-2883 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Major and minor crRNA annealing sites facilitate low stringency DNA protospacer binding prior to Type I-A CRISPR-Cas interference in Sulfolobus

    Mousaei, M., Deng, Ling, She, Q. & Garrett, Roger Antony, 2016, In: R N A Biology. 13, 11, p. 1166-1173 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Making sense of plant autoimmunity and "negative regulators'

    Rodriguez, Eleazar, Ghoul, H. E., Mundy, J. & Petersen, Morten, 2016, In: F E B S Journal. 283, 8, p. 1385-1391 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Mechanisms of bacterial persistence during stress and antibiotic exposure

    Harms, A., Maisonneuve, E. & Gerdes, K., 2016, In: Science. 354, 6318, 10 p., aaf4268.

    Research output: Contribution to journalReviewResearchpeer-review

  62. Published

    Microbiology: pumping persisters

    Gerdes, K. & Semsey, S., 2016, In: Nature. 534, 7605, p. 41-42 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  63. Published

    Mining Hot Springs for Biodiversity and Novel Enzymes

    Islin, S. R., 2016, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  64. Published

    Modulation of backbone flexibility for effective dissociation of antibacterial and hemolytic activity in cyclic peptides

    Oddo, A., Thomsen, T. T., Britt, H. M., Løbner-Olesen, Anders, Thulstrup, Peter Waaben, Sanderson, J. M. & Hansen, Paul Robert, 2016, In: ACS Medicinal Chemistry Letters. 7, 8, p. 741-745 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance

    Pinela da Silva, S. C., Altmannova, V., Luke-Glaser, S., Henriksen, P., Gallina, I., Yang, X., Choudhary, Chunaram, Luke, B., Krejci, L. & Lisby, Michael, 2016, In: Genes & Development. 30, 6, p. 700-717 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Multiple DNA binding proteins contribute to timing of chromosome replication in E. coli

    Riber, Leise, Frimodt-Møller, Jakob, Charbon, Godefroid & Løbner-Olesen, Anders, 2016, In: Frontiers in Molecular Biosciences. 3, 9 p., 29.

    Research output: Contribution to journalReviewResearchpeer-review

  67. Published

    Multiple consecutive initiation of replication producing novel brush-like intermediates at the termini of linear viral dsDNA genomes with hairpin ends.

    Martinez Alvarez, Laura, Bell, S. D. & Peng, Xu, 2016, In: Nucleic Acids Research. 44, 18, p. 8799-8809 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Novel viral genomes identified from six metagenomes reveal wide distribution of archaeal viruses and high viral diversity in terrestrial hot springs

    Islin, S. R., Menzel, P., Krogh, Anders, Young, M. & Peng, Xu, 2016, In: Environmental Microbiology. 18, 3, p. 863-874 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Nucleation and spreading of a heterochromatic domain in fission yeast

    Obersriebnig, M. J., Pallesen, E. M. H., Sneppen, Kim, Trusina, Ala & Thon, Genevieve, 2016, In: Nature Communications. 7, 11 p., 11518.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Pro-recombination role of Srs2 protein requires SUMO (small ubiquitin-like modifier) but is independent of PCNA (proliferating cell nuclear antigen) interaction

    Kolesar, P., Altmannova, V., Pinela da Silva, S. C., Lisby, Michael & Krejci, L., 2016, In: Journal of Biological Chemistry. 291, 14, p. 7594-7607 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Protein Kinase Signalling in the Moss Physcomitrella patens

    Azevedo de Silva, R., 2016, Department of Biology, Faculty of Science, University of Copenhagen. 109 p.

    Research output: Book/ReportPh.D. thesisResearch

  72. Published

    Recognition of extremophilic archaeal viruses by eukaryotic cells: a promising nanoplatform from the third domain of life

    Uldahl, K. B., Wu, L., Hall, A., Papathanasiou, P., Peng, Xu & Moghimi, S. M., 2016, In: Scientific Reports. 6, 37966.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Regulating retrotransposon activity through the use of alternative transcription start sites

    Persson, J., Steglich, B., Smialowska, A., Boyd, M., Lange, Jette Bornholdt, Andersson, Robin, Schurra, C., Arcangioli, B., Sandelin, Albin Gustav, Nielsen, Olaf & Ekwall, K., 2016, In: E M B O Reports. 17, 5, p. 753-768 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP

    Sheppard, C., Blombach, F., Belsom, A., Schulz, S., Daviter, T., Smollett, K., Mahieu, E., Erdmann, S., Tinnefeld, P., Garrett, Roger Antony, Grohmann, D., Rappsilber, J. & Werner, F., 2016, In: Nature Communications. 7, 13 p., 13595.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    SUMO-dependent relocalization of eroded telomeres to nuclear pore complexes controls telomere recombination

    Churikov, D., Charifi, F., Eckert-Boulet, N. V., Pinela da Silva, S. C., Simon, M., Lisby, Michael & Géli, V., 2016, In: Cell Reports. 15, 6, p. 1242-1253 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination

    Pinela da Silva, S. C., Altmannova, V., Eckert-Boulet, N. V., Kolesar, P., Gallina, I., Hang, L., Chun, I., Arneric, M., Zhao, X., Buron, L. D., Mortensen, U. H., Krejci, L. & Lisby, Michael, 2016, In: D N A Repair. 42, p. 11-25 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Secretion of alpha-hemolysin by Escherichia coil disrupts tight junctions in ulcerative colitis patients

    Mirsepasi-Lauridsen, H. C., Du, Z., Struve, C., Charbon, Godefroid, Karczewski, J., Krogfelt, K. A., Petersen, A. M. & Wells, J. M., 2016, In: Clinical and Translational Gastroenterology. 7, 9 p., e149.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Stability of Hyperthermophilic Proteins: Post-translational modification and other factors

    Stiefler-Jensen, D., 2016, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  79. Published

    Structural analysis of sumoylated proteins in Schizosaccharomyces pombe : with a special focus on the DNA binding protein Sap1

    Jørgensen, M. L. M., 2016, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  80. Published

    Synchronization of S phase in Schizosaccharomyces pombe cells by transient exposure to M-factor pheromone

    Nielsen, Olaf, 2016, In: Cold Spring Harbor Protocols. 2016, 9, p. 768-772 5 p.

    Research output: Contribution to journalJournal articleResearch

  81. Published

    TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

    Moudry, P., Watanabe, K., Wolanin, K. M., Bartkova, J., Wassing, I. E., Watanabe, S., Strauss, R., Pedersen, R. T., Østergaard, Vibe Hallundbæk, Lisby, Michael, Andújar-Sánchez, M., Maya-Mendoza, A., Esashi, F., Lukas, Jiri & Bartek, J., 2016, In: The Journal of Cell Biology. 212, 3, p. 281-288 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    The apt/6-methylpurine counterselection system and its applications in genetic studies of the hyperthermophilic archaeon Sulfolobus islandicus

    Zhang, C., She, Q., Bi, H. & Whitaker, R. J., 2016, In: Applied and Environmental Microbiology. 82, 10, p. 3070-3081 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    The lantibiotic NAI-107 efficiently rescues Drosophila melanogaster from infection with methicillin-resistant Staphylococcus aureus USA300

    Thomsen, T. T., Mojsoska, B., Cruz, J. C. S., Donadio, S., Jenssen, H., Løbner-Olesen, Anders & Rewitz, Kim, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 9, p. 5427-5436 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    The transcriptional regulator GalR self-assembles to form highly regular tubular structures

    Agerschou, E. D., Christiansen, G., Schafer, N. P., Madsen, D. J., Brodersen, D. E., Semsey, S. & Otzen, D. E., 2016, In: Scientific Reports. 6, 13 p., 27672 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    TopBP1 makes the final call for repair on the verge of cell division

    Østergaard, Vibe Hallundbæk & Lisby, Michael, 2016, In: Molecular & Cellular Oncology. 3, 2, 3 p., e1093066.

    Research output: Contribution to journalReviewResearchpeer-review

  86. Published

    TopBP1-mediated DNA processing during mitosis

    Gallina, I., Christiansen, S. K., Pedersen, R. T., Lisby, Michael & Østergaard, Vibe Hallundbæk, 2016, In: Cell Cycle. 15, 2, p. 176-183 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Transcriptome changes in STSV2-infected Sulfolobus islandicus REY15A undergoing continuous CRISPR spacer acquisition

    León Sobrino, C., Kot, W. P. & Garrett, Roger Antony, 2016, In: Molecular Microbiology. 99, 4, p. 719-728 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Uropathogenic Escherichia coli metabolite-dependent quiescence and persistence may explain antibiotic tolerance during urinary tract infection

    Leatham-Jensen, M. P., Mokszycki, M. E., Rowley, D. C., Deering, R., Camberg, J. L., Sokurenko, E. V., Tchesnokova, V. L., Frimodt-Møller, Jakob, Krogfelt, K. A., Nielsen, K. L., Frimodt-Møller, N., Sun, G. & Cohen, P. S., 2016, In: mSphere. 1, 1, 22 p., e00055-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation

    Winther, K. S., Tree, J. J., Tollervey, D. & Gerdes, K., 2016, In: Nucleic Acids Research. 44, 20, p. 9860-9871 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Viruses of the Archaea

    Prangishvili, D., Basta, T., Garrett, Roger Antony & Krupovic, M., 2016, In: eLS. 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  91. 2015
  92. Published

    Immunogenic and protective efficacy of recombinant protein GtxA-N against Gallibacterium anatis challenge in chickens

    Pedersen, I. J., Pors, S. E., Skjerning, R. B., Nielsen, Søren Saxmose & Bojesen, Anders Miki, Oct 2015, In: Avian pathology : journal of the W.V.P.A. 44, 5, p. 386-391 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Coupled positive and negative feedbacks produce diverse gene expression patterns in colonies

    Mitarai, Namiko, Jensen, Mogens Høgh & Semsey, S., 7 Apr 2015, In: mBio (Print). 6, 2, e00059-15 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition

    Liu, T., Li, Y., Wang, X., Ye, Q., Li, H., Liang, Y., She, Q. & Peng, N., 30 Jan 2015, In: Nucleic Acids Research. 43, 2, p. 1044-1055 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Adenylylation of gyrase and topo IV by FicT toxins disrupts bacterial DNA topology

    Harms, A., Stanger, F. V., Scheu, P. D., de Jong, I. G., Goepfert, A., Glatter, T., Gerdes, K., Schirmer, T. & Dehio, C., 2015, In: Cell Reports. 12, 9, p. 1497-1507 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    An IPTG-inducible derivative of the fission yeast nmt promoter

    Kjærulff, S. & Nielsen, Olaf, 2015, In: Yeast. 32, p. 469-478 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference

    Peng, W., Feng, M., Feng, X., Liang, Y. X. & She, Q., 2015, In: Nucleic Acids Research. 43, 1, p. 406-417 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    An updated evolutionary classification of CRISPR-Cas systems

    Makarova, K. S., Wolf, Y. I., Alkhnbashi, O. S., Costa, F., Shah, S. A., Saunders, S. J., Barrangou, R., Brouns, S. J. J., Charpentier, E., Haft, D. H., Horvath, P., Moineau, S., Mojica, F. J. M., Terns, R. M., Terns, M. P., White, M. F., Yakunin, A. F., Garrett, R. A., van der Oost, J., Backofen, R. & 1 others, Koonin, E. V., 2015, In: Nature Reviews. Microbiology. 13, 11, p. 722-736 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Archaeal extrachromosomal genetic elements

    Wang, H., Peng, N., Shah, S. A., Huang, L. & She, Q., 2015, In: Microbiology and Molecular Biology Reviews. 79, 1, p. 117-152 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Archaeal viruses of the sulfolobales: isolation, infection, and CRISPR spacer acquisition

    Erdmann, S. & Garrett, Roger Antony, 2015, CRISPR: methods and protocols. Lundgren, M., Charpentier, E. & Fineran, P. C. (eds.). Springer, p. 223-232 10 p. (Methods in Molecular Biology, Vol. 1311).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  101. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    CRISPR-Cas adaptive immune systems of the sulfolobales: unravelling their complexity and diversity

    Garrett, Roger Antony, Shah, S. A., Erdmann, S., Guannan, L., Mousaei, M., León Sobrino, C., Peng, W., Islin, S. R., Deng, Ling, Vestergaard, G., Peng, Xu & She, Q., 2015, In: Life. 5, 1, p. 783-817 35 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Cell age dependent concentration of Escherichia coli divisome proteins analyzed with ImageJ and ObjectJ

    Vischer, N. O. E., Verheul, J., Postma, M., van Saparoea, B. V. D. B., Galli, E., Natale, P., Gerdes, K., Luirink, J., Vollmer, W., Vicente, M. & den Blaauwen, T., 2015, In: Frontiers in Microbiology. 6, 18 p., 586.

    Research output: Contribution to journalJournal articleResearchpeer-review

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