The sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombe
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
The sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombe. / Ladds, G; Rasmussen, E M; Young, T; Nielsen, O; Davey, William John; Nielsen, Olaf.
In: Molecular Microbiology, Vol. 20, No. 1, 01.04.1996, p. 35-42.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - The sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombe
AU - Ladds, G
AU - Rasmussen, E M
AU - Young, T
AU - Nielsen, O
AU - Davey, William John
AU - Nielsen, Olaf
PY - 1996/4/1
Y1 - 1996/4/1
N2 - Haploid cells of the fission yeast Schizosaccharomyces pombe exist in one of two mating types, referred to as M and P. Conjugation occurs between cells of opposite mating type and is controlled by the reciprocal action of diffusible pheromones. Loss of function of the sxa2 gene in M cells causes hypersensitivity to the P-factor mating pheromone and a reduction in mating efficiency. Here we demonstrate the secretion of an sxa2-dependent carboxypeptidase that inactivates P-factor by removal of the C-terminal leucine residue.
AB - Haploid cells of the fission yeast Schizosaccharomyces pombe exist in one of two mating types, referred to as M and P. Conjugation occurs between cells of opposite mating type and is controlled by the reciprocal action of diffusible pheromones. Loss of function of the sxa2 gene in M cells causes hypersensitivity to the P-factor mating pheromone and a reduction in mating efficiency. Here we demonstrate the secretion of an sxa2-dependent carboxypeptidase that inactivates P-factor by removal of the C-terminal leucine residue.
KW - Carboxypeptidases
KW - Gene Expression Regulation, Fungal
KW - Genes, Fungal
KW - Genes, Mating Type, Fungal
KW - Hydrogen-Ion Concentration
KW - Pheromones
KW - Schizosaccharomyces
KW - Schizosaccharomyces pombe Proteins
KW - Temperature
KW - Transcription Factors
M3 - Journal article
C2 - 8861202
VL - 20
SP - 35
EP - 42
JO - Molecular Microbiology
JF - Molecular Microbiology
SN - 0950-382X
IS - 1
ER -
ID: 33577134