Cell Biology and Physiology

  1. Published

    Evidence for a stem cell hierarchy in the adult human breast

    Villadsen, René, Fridriksdottir, A. J., Rønnov-Jessen, Lone, Gudjonsson, T., Rank, F., LaBarge, M. A., Bissell, M. J. & Petersen, Ole William, 2007, In: Journal of Cell Biology. 177, 1, p. 87-101 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Expression, regulation and function of epithelial-stromal interaction 1 (breast), EPSTI1

    Villadsen, R., Lind Nielsen, H., Rank, F., Petersen, O. W., Rønnov-Jessen, Lone & Neergaard, M. D., 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 5, p. 430-431 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  3. Published

    The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis

    Villalobo, A. & Berchtold, Martin Werner, 2020, In: International Journal of Molecular Sciences (Online). 21, 3, 42 p., 765.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Calmodulin as a protein linker and a regulator of adaptor/scaffold proteins

    Villalobo, A., Ishida, H., Vogel, H. J. & Berchtold, Martin Werner, 2018, In: B B A - Molecular Cell Research. 1865, 3, p. 507-521 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Proteins with calmodulin-like domains: structures and functional roles

    Villalobo, A., González-Muñoz, M. & Berchtold, Martin Werner, 2019, In: Cellular and Molecular Life Sciences. 76, 12, p. 2299-2328

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Acute cholesterol depletion leads to net loss of the organic osmolyte taurine in Ehrlich Lettré tumor cells

    Villumsen, Kasper Rømer, Duelund, L. & Lambert, Ian Henry, 1 Nov 2010, In: Amino Acids. 39, 5, p. 1521-36 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Production of an Active, Human Membrane Protein in Saccharomyces cerevisiae: Full-Length FICD

    Virolainen, M. S., Søltoft, C. L., Pedersen, Per Amstrup & Ellgaard, Lars, 2022, In: International Journal of Molecular Sciences. 23, 5, 17 p., 2458.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Regulation and structural aspects of the human Na+/H+ exchanger NHE1: Roles of the N-terminal region and interactions with lipids

    Vogensen, J., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  9. Published

    pXOOY: A dual-function vector for expression of membrane proteins in Saccharomyces cerevisiae and Xenopus laevis oocytes

    Vold, Victoria Amstrup, Glanville, S., Klærke, Dan Arne & Pedersen, Per Amstrup, 2023, In: PLoS ONE. 18, 2, 16 p., e0281868.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The retinoblastoma protein: multitasking to suppress tumorigenesis

    Vormer, T. L., Hansen, Jacob B. & Riele, H. T., 2015, In: Molecular & Cellular Oncology. 2, 1, 2 p., e968062-1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Molecular size and charge characterization by rheophoresis I. Theory and gel calibration

    Waldmann‐Meyer, H. & Pedersen, Per Amstrup, 1 Jan 1984, In: Electrophoresis. 5, 1, p. 18-21 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    An outbreak of human salmonellosis in Denmark caused by alfalfa sprouts

    Wegener, H. C., Baggesen, D. L. & Nielsen, S. V., 1997.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  14. Published

    Pseudomonas aeruginosa and Saccharomyces cerevisiae biofilm in flow cells

    Weiss Nielsen, M., Sternberg, C., Molin, S. & Regenberg, Birgitte, 2011, In: Journal of Visualized Experiments. 47, p. pii:2383

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    BIND&MODIFY: a long-range method for single-molecule mapping of chromatin modifications in eukaryotes

    Weng, Z., Ruan, F., Chen, W., Chen, Z., Xie, Y., Luo, M., Xie, Z., Zhang, C., Wang, J., Sun, Y., Fang, Y., Guo, M., Tan, C., Chen, W., Tong, Y., Li, Y., Wang, H. & Tang, C., 2023, In: Genome Biology. 24, 1, 29 p., 61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF)

    Willerslev-Olsen, A., Litvinov, I. V., Fredholm, S. M., Petersen, D. L., Sibbesen, N. A., Gniadecki, R., Zhang, Q., Bonefeld, Charlotte Menne, Wasik, M. A., Geisler, Carsten, Zhou, Y., Woetmann, Anders , Sasseville, D., Krejsgaard, T. & Ødum, Niels, 15 Apr 2014, In: Cell Cycle. 13, 8, p. 1306-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Further genetic localization of the transforming sequences of the p21 v-ras gene of Harvey murine sarcoma virus.

    Willumsen, Berthe Marie, Ellis, R. W., Willumsen, Berthe Marie & Lowy, D. R., 1984, In: Journal of Virology. 49, 2, p. 601-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The p21 ras C-terminus is required for transformation and membrane association.

    Willumsen, Berthe Marie, Christensen, A., Hubbert, N. L., Papageorge, A. G. & Lowy, D. R., 1984, In: Nature. 310, 5978, p. 583-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Novel determinants of H-Ras plasma membrane localization and transformation.

    Willumsen, Berthe Marie, Cox, A. D., Solski, P. A., Der, C. J. & Buss, J. E., 1996, In: Oncogene. 13, 9, p. 1901-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Mutational analysis of a ras catalytic domain.

    Willumsen, Berthe Marie, Papageorge, A. G., Kung, H. F., Bekesi, E., Robins, T., Johnsen, M., Vass, W. C. & Lowy, D. R., 1986, In: Molecular and Cellular Biology. 6, 7, p. 2646-54 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    In vitro selection of high-infectious, leukemogenic virus from low-infectious, non-leukemogenic type C virus from a malignant ST/a mouse cell line.

    Willumsen, Berthe Marie, 1979, In: Journal of Virology. 29, 3, p. 1213-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.

    Willumsen, Berthe Marie, Vass, W. C., Velu, T. J., Papageorge, A. G., Schiller, J. T. & Lowy, D. R., 1991, In: Molecular and Cellular Biology. 11, 12, p. 6026-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Serological identification of neoantigens on mouse fibroblasts which have undergone "spontaneous" malignant alteration in vitro.

    Willumsen, Berthe Marie, Ulrich, K. & Kieler, J., 1979, In: International Journal of Cancer. 23, 2, p. 209-16 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains.

    Willumsen, Berthe Marie, Papageorge, A. G., Hubbert, N., Bekesi, E., Kung, H. F. & Lowy, D. R., 1985, In: EMBO Journal. 4, 11, p. 2893-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

    Willumsen, Berthe Marie, Norris, K., Papageorge, A. G., Hubbert, N. L. & Lowy, D. R., 1984, In: EMBO Journal. 3, 11, p. 2581-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

    Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Loss of SHP-1 tyrosine phosphatase expression correlates with the advanced stages of cutaneous T-cell lymphoma

    Witkiewicz, A., Raghunath, P., Wasik, A., Junkins-Hopkins, J. M., Jones, D., Zhang, Q., Ødum, Niels & Wasik, M. A., 2007, In: Human Pathology. 38, 3, p. 462-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Division of labour in the yeast: Saccharomyces cerevisiae

    Wloch-Salamon, D. M., Fisher, Roberta May & Regenberg, Birgitte, Oct 2017, In: Yeast. 34, 10, p. 399-406 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins

    Woetmann, Anders , Lovato, P., Eriksen, K. W., Krejsgaard, T., Labuda, T., Zhang, Q., Mathiesen, A., Geisler, Carsten, Svejgaard, A., Wasik, M. A. & Ødum, Niels, 2007, In: Blood. 109, 8, p. 3325-32 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling

    Woetmann, Anders , Brockdorff, J., Lovato, P., Nielsen, M., Leick, V., Rieneck, K., Svejgaard, A., Geisler, Carsten & Ødum, Niels, 2002, In: Journal of Biological Chemistry. 278, 5, p. 2787-91 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Co-expression of mCysLT1 receptors and IK channels in Xenopus laevis oocytes elicits LTD4-stimulated IK current, independent of an increase in [Ca2+]i.

    Wulff, T., Hougaard, C., Klærke, Dan Arne & Hoffmann, E. K., 2004, In: BBA General Subjects. 1660, 1-2, p. 75-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Investigation of two different anoxia models by 2-dimensional gel electrophoresis

    Wulff, T., Jessen, F. & Hoffmann, E. K., 2006, In: The FASEB Journal. 5, p. A1433

    Research output: Contribution to journalConference abstract in journalResearch

  33. Published

    Comparison of two anoxia models in rainbow trout cells by a 2-DE and MS/MS-based proteome approach.

    Wulff, T., Hoffmann, E. K., Roepstorff, P. & Jessen, F., 2008, In: Proteomics. 8, 10, p. 2035-44 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Novel Sequencing Approaches for the High-Throughput Identification of Full-length Poly(A) RNA Transcripts at the Single-cell Level

    XIE, Z., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 88 p.

    Research output: Book/ReportPh.D. thesisResearch

  35. Published

    Identification and functional analysis of circulating extrachromosomal circular DNA in schizophrenia implicate its negative effect on the disorder

    Xiang, X., Pan, Xiaoguang, Lv, W., Chen, S., Li, J., Zhang, H., Liao, Y., Yu, J., Li, J., Dang, Y., You, Z., Wang, L., Chen, W., Han, Peng & Tang, J., 2023, In: Clinical and Translational Medicine. 13, 11, 7 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  36. Published

    Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers

    Xie, Y., Ruan, F., Li, Y., Luo, M., Zhang, C., Chen, Z., Xie, Z., Weng, Z., Chen, W., Chen, W., Fang, Y., Sun, Y., Guo, M., Wang, J., Xu, S., Wang, H. & Tang, C., 2024, In: eLife. 12, 20 p., RP87868.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Transcriptomic Profile of the Mouse Postnatal Liver Development by Single-Nucleus RNA Sequencing

    Xu, J., Hao, S., Shi, Q., Deng, Q., Jiang, Y., Guo, P., Yuan, Y., Shi, X., Shangguan, S., Zheng, H., Lai, G., Huang, Y., Wang, Y., Song, Y., Liu, Y., Wu, L., Wang, Z., Cheng, J., Wei, X., Cheng, M. & 6 others, Lai, Y., Volpe, G., Esteban, M. A., Hou, Y., Liu, C. & Liu, L., 2022, In: Frontiers in Cell and Developmental Biology. 10, 11 p., 833392.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival

    Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Expression of calmodulin and calmodulin binding proteins in rat fibroblasts stably transfected with protein kinase C and oncogenes

    Ye, Q., Wei, Y., Fischer, R., Borner, C. & Berchtold, Martin Werner, 1997, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1359, 1, p. 89-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Structure and expression of the chicken calmodulin I gene

    Ye, Q. & Berchtold, Martin Werner, 1997, In: Gene. 194, 1, p. 63-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Human epidermal growth factor receptor 2 status in urothelial bladder carcinoma: Frequency, genomic patterns and clinical significance

    Yu, T., Tao, H., Lv, W., Liang, N., Cui, X., Sui, X., Pan, Y., Wu, S., Xiang, C., Li, Y., Zeng, Y., Li, Conghui, Wang, F., Han, Peng, Wang, W., Yu, G. & Lin, C., 2023, In: Clinical and Translational Discovery. 3, 5, 4 p., e245.

    Research output: Contribution to journalComment/debateResearchpeer-review

  42. Published

    Cultivation and sequencing of commensal bacteria of the human gut through culture-based and metagenomics analyses

    ZOU, Y., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 154 p.

    Research output: Book/ReportPh.D. thesisResearch

  43. Published

    In silico analysis of the transportome in human pancreatic ductal adenocarcinoma

    Zaccagnino, A., Pilarsky, C., Tawfik, D., Sebens, S., Trauzold, A., Novak, Ivana, Schwab, A. & Kalthoff, H., 2016, In: European Biophysics Journal. 45, 7, p. 749-763 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    PRIMA-1Met/APR-246 induces apoptosis and tumor growth delay in small cell lung cancer expressing mutant p53

    Zandi, R., Selivanova, G., Christensen, C. L., Gerds, Thomas Alexander, Willumsen, Berthe Marie & Poulsen, H. S., 1 May 2011, In: Clinical Cancer Research. 17, 9, p. 2830-2841 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Assessment of different 3D culture systems to study tumor phenotype and chemosensitivity in pancreatic ductal adenocarcinoma

    Zeeberg, K., Cardone, R. A., Greco, M. R., Saccomano, M., Nøhr-Nielsen, A., Alves, F., Pedersen, Stine Helene Falsig & Reshkin, S. J., 2016, In: International Journal of Oncology. 49, 1, p. 243-252 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

    Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Isolation and Crystallization of the D156C Form of Optogenetic ChR2

    Zhang, L., Wang, Kaituo, Ning, S., Pedersen, Per Amstrup, Duelli, A. S. & Gourdon, Pontus Emanuel, 2022, In: Cells. 11, 5, 11 p., 895.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter

    Zhang, Q., Raghunath, P. N., Vonderheid, E., Ødum, Niels & Wasik, M. A., 2000, In: American Journal of Pathology. 157, 4, p. 1137-46 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

    Zhang, Q., Raghunath, P. N., Xue, L., Majewski, M., Carpentieri, D. F., Ødum, Niels, Morris, S., Skorski, T. & Wasik, M. A., 2002, In: Journal of Immunology. 168, 1, p. 466-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

    Zhang, Q., Wang, H. Y., Woetmann, Anders , Raghunath, P. N., Ødum, Niels & Wasik, M. A., 2006, In: Blood. 108, 3, p. 1058-64 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review