Cell Biology and Physiology

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  1. 2022
  2. Published

    Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase

    Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials

    Pilmark, N. S., Oberholzer, L., Halling, Jens Frey, Kristensen, Jonas Møller, Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, Jesper Bratz, Larsen, E. L., Meinild-Lundby, A., Wojtaszewski, Jørgen F P, Pilegaard, Henriette, Poulsen, H., Pedersen, Bente Klarlund, Hansen, K. B. & Karstoft, Kristian, 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Sodium, Glucose and Dysregulated Glucagon Secretion: The Potential of Sodium Glucose Transporters

    Armour, Sarah Louise, Früh, Alexander Erwin & Knudsen, Jakob Grunnet, 2022, In: Frontiers in Pharmacology. 13, 6 p., 837664.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Structural basis of ion uptake in copper-transporting P1B-type ATPases

    Salustros, N., Gronberg, C., Abeyrathna, N. S., Lyu, Pin, Oradd, F., Wang, Kaituo, Andersson, M., Meloni, G. & Gourdon, Pontus Emanuel, 2022, In: Nature Communications. 13, 1, 11 p., 5121.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Structure and functional analysis of PIB-type ATPases

    Lyu, Pin, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 281 p.

    Research output: Book/Report › Ph.D. thesis › Research

  8. Published

    Targeted removal of mitochondrial DNA from mouse and human extrachromosomal circular DNA with CRISPR-Cas9

    Feng, Weijia, Arrey Tané, Gerard, Zole, Egija, Iv, W., Liang, Xue, Han, Peng, Mohiyuddin, M., Pilegaard, Henriette & Regenberg, Birgitte, 2022, In: Computational and Structural Biotechnology Journal. 20, p. 3059-3067 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The FASTQ+ format and PISA

    Shi, Quan, Liu, S., Kristiansen, Karsten & Liu, L., 2022, In: Bioinformatics. 38, 19, p. 4639-4642 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca2+-Independent Manner

    Schnipper, J., Kouba, S., Hague, F., Girault, A., Rybarczyk, P., Telliez, M., Guenin, S., Tebbakha, R., Sevestre, H., Ahidouch, A., Pedersen, Stine Helene Falsig & Ouadid-Ahidouch, H., 2022, In: International Journal of Molecular Sciences . 23, 14, 20 p., 7923.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The role of water coordination in the pH-dependent gating of hAQP10

    Truelsen, S. F., Missel, Julie Winkel, Gotfryd, K., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel, Lindorff-Larsen, Kresten & Hélix-Nielsen, C., 2022, In: B B A - Biomembranes. 1864, 1, 13 p., 183809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The use of paracetamol during pregnancy: A qualitative study and possible strategies for a clinical trial

    Vedel, C., Jørgensen, D. S., Kristensen, D. M., Petersen, Olav Bennike Bjørn & Greisen, Gorm, 2022, In: PLoS ONE. 17, e0271537.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Time-dependent regulation of hepatic cytochrome P450 mRNA in male liver-specific PGC-1α knockout mice

    Sundekilde, U. K., Kristensen, C. M., Olsen, M. A., Pilegaard, Henriette & Rasmussen, M. K., 2022, In: Toxicology. 469, 8 p., 153121.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Transcriptomic Profile of the Mouse Postnatal Liver Development by Single-Nucleus RNA Sequencing

    Xu, J., Hao, S., Shi, Q., Deng, Q., Jiang, Y., Guo, P., Yuan, Y., Shi, X., Shangguan, S., Zheng, H., Lai, G., Huang, Y., Wang, Y., Song, Y., Liu, Y., Wu, L., Wang, Z., Cheng, J., Wei, X., Cheng, M. & 6 others, Lai, Y., Volpe, G., Esteban, M. A., Hou, Y., Liu, C. & Liu, L., 2022, In: Frontiers in Cell and Developmental Biology. 10, 11 p., 833392.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2023
  16. Published

    Actinarctus doryphorus (Tanarctidae) DNA barcodes and phylogenetic reinvestigation of Arthrotardigrada with new A. doryphorus and Echiniscoididae sequences

    Grollmann, M. M., Jørgensen, Aslak & Møbjerg, Nadja, 2023, In: Zootaxa. 5284, 2, p. 351-363 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A genome and single-nucleus cerebral cortex transcriptome atlas of the short-finned pilot whale Globicephala macrorhynchus

    Kang, H., Liu, Qun, Seim, I., Zhang, W., Li, H., Gao, H., Lin, W., Lin, M., Zhang, P., Zhang, Y., Gao, H., Wang, Y., Qin, Yating, Liu, M., Dong, L., Yang, Z., Zhang, Y., Han, L., Fan, G. & Li, S., 2023, In: Molecular Ecology Resources. 23, 5, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A single-cell atlas of West African lungfish respiratory system reveals evolutionary adaptations to terrestrialization

    Zhang, R., Liu, Q., Pan, S., Zhang, Y., Qin, Y., Du, X., Yuan, Z., Lu, Y., Song, Y., Zhang, M., Zhang, N., Ma, J., Zhang, Z., Jia, X., Wang, K., He, S., Liu, S., Ni, M., Liu, X., Xu, X. & 4 others, Yang, H., Wang, J., Seim, I. & Fan, G., 2023, In: Nature Communications. 14, 1, 15 p., 5630.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome

    G. Aslanyan, M., Doornbos, C., D. Diwan, G., Anvarian, Zeinab, Beyer, T., Junger, K., E. C. van Beersum, S., Russell, R., Ueffing, M., Ludwig, A., Boldt, K., Pedersen, Lotte Bang & Roepman, R., 2023, In: Frontiers in Cell and Developmental Biology. 11, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Amino acids and the changing face of the α-cell

    Hamilton, Alexander, Eliasson, L. & Knudsen, Jakob Grunnet, 2023, In: Peptides. 166, 7 p., 171039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    An insulin hypersecretion phenotype precedes pancreatic β cell failure in MODY3 patient-specific cells

    Hermann, F. M., Kjærgaard, M. F., Tian, C., Tiemann, Ulf, Jackson, Abigail Laura, Olsen, L. R., Kraft, M., Carlsson, P. O., Elfving, I. M., Kettunen, J. L. T., Tuomi, T., Novak, Ivana & Semb, Tor Henrik, 2023, In: Cell Stem Cell. 30, 1, p. 38-51.e8 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Aquaporin water channels affect the response of conventional anticancer therapies of 3D grown breast cancer cells

    Edamana, S., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2023, In: Biochemical and Biophysical Research Communications. 639, p. 126-133 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    BIND&MODIFY: a long-range method for single-molecule mapping of chromatin modifications in eukaryotes

    Weng, Z., Ruan, F., Chen, W., Chen, Z., Xie, Y., Luo, M., Xie, Z., Zhang, C., Wang, J., Sun, Y., Fang, Y., Guo, M., Tan, C., Chen, W., Tong, Y., Li, Y., Wang, H. & Tang, C., 2023, In: Genome Biology. 24, 1, 29 p., 61.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Chronic acidosis rewires cancer cell metabolism through PPARα signaling

    Rolver, M. G., Holland, L. K. K., Ponniah, M., Prasad, N. S., Yao, Jiayi, Schnipper, J., Kramer, S., Elingaard-Larsen, L., Pedraz-Cuesta, E., Liu, B., Pardo, L. A., Maeda, K., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 8, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Cilia and flagella

    Pedersen, Lotte Bang, Jurisch-Yaksi, N., Schmid, F. M. & Christensen, Søren Tvorup, 2023, Encyclopedia of Cell Biology, Second Edition. Bradshaw, R. A., Hart, G. W. & Stahl, P. D. (eds.). 2 ed. Oxford: Elsevier, Vol. 3. p. 164-188 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  26. Published

    Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness

    Czaplinska, D., Ialchina, Renata, Andersen, Henriette Berg, Yao, Jiayi, Stigliani, Arnaud, Dannesboe, Johs, Flinck, M., Chen, X., Mitrega, J., Gnosa, S. P., Dmytriyeva, O., Alves, F., Napp, J., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 6, p. 1210-1225 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Cultivation and sequencing of commensal bacteria of the human gut through culture-based and metagenomics analyses

    ZOU, Y., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 154 p.

    Research output: Book/Report › Ph.D. thesis › Research

  28. Published

    Dynamic localization of the Na+-HCO3- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia

    Severin, M., Pedersen, E. L., Borre, M. T., Axholm, I., Christiansen, F. B., Ponniah, M., Czaplinska, D., Larsen, T., Pardo, L. A. & Pedersen, Stine Helene Falsig, 2023, In: Journal of Cell Science. 136, 7, 20 p., jcs260687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Editorial: Signaling by primary cilia in development and disease

    Kim, S. E., Nechipurenko, I. & Christensen, Søren Tvorup, 2023, In: Frontiers in Cell and Developmental Biology. 11, 3 p., 1186367.

    Research output: Contribution to journal › Editorial › Research › peer-review

  30. Published

    Effects of acid-adaptation on cancer cell acid-base regulation, metabolism and stemness

    Rolver, M. G., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 190 p.

    Research output: Book/Report › Ph.D. thesis › Research

  31. Published

    Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison

    Panou, D. A., Pedersen, Stine Helene Falsig, Kristensen, Mie & Nielsen, Hanne Mørck, 2023, In: Frontiers in Drug Delivery. 3, 16 p., 1221628.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Expression of genes and enzymes involved in ovarian steroidogenesis in relation to human follicular development

    Zheng, M., tcg964, tcg964, Rasmussen, F. R., Cadenas, J., Christensen, Søren Tvorup & Mamsen, L. S., 2023, In: Frontiers in Endocrinology. 14, 17 p., 1268248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Full activation of thermogenesis in brown adipocytes requires Basigin action

    Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism

    Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes

    Rönn, T., Ofori, J. K., Perfilyev, A., Hamilton, Alexander, Pircs, K., Eichelmann, F., Garcia-Calzon, S., Karagiannopoulos, A., Stenlund, H., Wendt, A., Volkov, P., Schulze, M. B., Mulder, H., Eliasson, L., Ruhrmann, S., Bacos, K. & Ling, C., 2023, In: Nature Communications. 14, 1, 21 p., 8040.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Genome-wide characterization of extrachromosomal circular DNA in gastric cancer and its potential role in carcinogenesis and cancer progression

    Jiang, X., Pan, Xiaoguang, Li, W., Han, Peng, Yu, J., Li, J., Zhang, H., Lv, W., Zhang, Y., He, Y. & Xiang, X., 2023, In: Cellular and Molecular Life Sciences. 80, 7, 18 p., 191.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells

    Armour, Sarah Louise, Frueh, A., Chibalina, M. V., Dou, H., Argemi Muntadas, Lidia, Hamilton, Alexander, Katzilieris Petras, Georgios, Carmeliet, P., Davies, B., Moritz, Thomas, Eliasson, L., Rorsman, P. & Knudsen, Jakob Grunnet, 2023, In: Diabetes. 72, 10, p. 1446-1459 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Hepatic PGC-1α has minor regulatory effect on the liver transcriptome and metabolome during high fat high fructose diet and exercise training

    Rasmussen, M. K., Thøgersen, R., Horsbøl Lindholm, P., Bertram, H. C. & Pilegaard, Henriette, 2023, In: Gene. 851, 14 p., 147039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Heterogeneous vasomotor responses in segments from Göttingen Minipigs coronary, cerebral, and mesenteric artery: A comparative study

    Nielsen, Anette Sams, Haanes, Kristian Agmund, Holm, A., Kazantzi, Spyridoula, Mikkelsen, L. F., Edvinsson, L., Brain, S. & Sheykhzade, Majid, 2023, In: Vascular Pharmacology. 153, 107231.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    How protons pave the way to aggressive cancers

    Swietach, P., Boedtkjer, E. & Pedersen, Stine Helene Falsig, 2023, In: Nature Reviews Cancer. 23, p. 825-841 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Human epidermal growth factor receptor 2 status in urothelial bladder carcinoma: Frequency, genomic patterns and clinical significance

    Yu, T., Tao, H., Lv, W., Liang, N., Cui, X., Sui, X., Pan, Y., Wu, S., Xiang, C., Li, Y., Zeng, Y., Li, Conghui, Wang, F., Han, Peng, Wang, W., Yu, G. & Lin, C., 2023, In: Clinical and Translational Discovery. 3, 5, 4 p., e245.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  42. Published

    Identification and functional analysis of circulating extrachromosomal circular DNA in schizophrenia implicate its negative effect on the disorder

    Xiang, X., Pan, Xiaoguang, Lv, W., Chen, S., Li, J., Zhang, H., Liao, Y., Yu, J., Li, J., Dang, Y., You, Z., Wang, L., Chen, W., Han, Peng & Tang, J., 2023, In: Clinical and Translational Medicine. 13, 11, 7 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  43. Published

    Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

    Jørgensen, Stine Ringholm, Gudiksen, Anders, Halling, Jens Frey, Qoqaj, A., Rasmussen, P. M., Prats Gavalda, Clara, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 3, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Increased exosomal Calmodulin in the urine of patients with diabetic kidney disease (DKD) may be derived from either CALM1, CALM2, CALM3 or from more than one of these genes

    Berchtold, Martin Werner, 2023, In: Clinica Chimica Acta. 548, 2 p., 117515.

    Research output: Contribution to journal › Letter › Research › peer-review

  45. Published

    Interactions between microenvironmental acidity and PDAC driver mutations studied in 3D organotypic culture

    Ialchina, Renata, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 261 p.

    Research output: Book/Report › Ph.D. thesis › Research

  46. Published

    Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4

    Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Alves, Eliana Carolina Goncalves, Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Lymph Vessels Associate with Cancer Stem Cells from Initiation to Malignant Stages of Squamous Cell Carcinoma

    Cazzola, Anna, Calzón Lozano, D., Menne, D. H., Dávila Pedrera, R., Liu, J., Peña-Jiménez, D., Fontenete, S., Halin, C. & Perez-Moreno, Mirna, 2023, In: International Journal of Molecular Sciences. 24, 17, 20 p., 13615.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Metabolic regulation of glucagon secretion

    Armour, Sarah Louise, Stanley, J. E., Cantley, J., Dean, E. D. & Knudsen, Jakob Grunnet, 2023, In: The Journal of endocrinology. 259, 1, 15 p., e230081.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Muscle PGC-1α modulates hepatic mitophagy regulation during aging

    Christensen, N. M., Jørgensen, Stine Ringholm, Buch, B. T., Gudiksen, Anders, Halling, Jens Frey & Pilegaard, Henriette, 2023, In: Experimental Gerontology. 172, 9 p., 112046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    New insights into osmobiosis and chemobiosis in tardigrades

    Hvidepil, L. K. B. & Møbjerg, Nadja, 2023, In: Frontiers in Physiology. 14, 9 p., 1274522.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Pharmacological Nature of the Purinergic P2Y Receptor Subtypes That Participate in the Blood Pressure Changes Produced by ADPβS in Rats

    Silva-Velasco, R. C., Villanueva-Castillo, B., Haanes, Kristian Agmund, MaassenVanDenBrink, A. & Villalón, C. M., 2023, In: Pharmaceuticals. 16, 12, 19 p., 1683.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Primary cilia as dynamic and diverse signalling hubs in development and disease

    Mill, P., Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2023, In: Nature Reviews. Genetics. 24, 21 p.

    Research output: Contribution to journal › Review › Research › peer-review

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